Pathogenesis of coxsackievirus B3-induced myocarditis: Role of macrophage migration inhibitory factor

Chinese Medical Journal

Volumn 125, Issue 1, 2012, Pages 50-55

  Yu, Xiao Hua ^a   Li, Shuang Jie ^b   Chen, Rui Zhen ^c   Yang, Ying Zhen ^c   Zhang, Ping ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

^b HUNAN CHILDREN'S HOSPITAL   (China)

^c FUDAN UNIVERSITY   (China)

Author keywords

Coxsackievirus B3; Inflammation; Interleukin 1 ; Macrophage migration inhibitory factor; Myocarditis; Tumor necrosis factor

Indexed keywords

CYTOKINE; INTERLEUKIN 1BETA; MACROPHAGE MIGRATION INHIBITION FACTOR; MESSENGER RNA; NEUTRALIZING ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; COXSACKIEVIRUS B3 INDUCED MYOCARDITIS; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART MUSCLE; HEART WEIGHT; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INOCULATION; MACROPHAGE MIGRATION INHIBITION; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL RATE; VIRUS MYOCARDITIS;

ANIMALS; COXSACKIEVIRUS INFECTIONS; ENTEROVIRUS B, HUMAN; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1BETA; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MALE; MICE; MICE, INBRED BALB C; MYOCARDITIS; MYOCARDIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84862935448     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2012.01.010     Document Type: Article

References (28)

1. Kandolf R, Hofschneider PH. Viral heart disease. Springer Semin Immunopathol 1989; 11: 1-13.
2. Calabrese F, Thiene G. Myocarditis and inflammatory cardiomyopathy: microbiological and molecular biological aspects. Cardiovasc Res 2003: 60: 11-25.
3. Dennert R, Crijns HJ, Heymans S. Acute viral myocarditis. Eur Heart J 2008; 29: 2073-2082.
4. Kearney MT, Cotton JM, Richardson PJ, Shah AM. Viral myocarditis and dilated cardiomyopathy: mechanisms, manifestations, and management. Postgrad Med J 2001; 77: 4-10.
5. Santos LL, Morand EF. Macrophage migration inhibitory factor: a key cytokine in RA, SLE and atherosclerosis. Clin Chim Acta 2009; 399: 1-7.
6. Bloom BR, Bennett B. Mechanism of a reaction in vitro associated with delayed-type hypersensitivity. Science 1966; 153: 80-82.
7. Nishihira J, Mitsuyama K. Overview of the role of macrophage migration inhibitory factor (MIF) in inflammatory bowel disease. Curr Pharm Des 2009; 15: 2104-2109.
8. Calandra T, Roger T. Macrophage migration inhibitory factor: a regulator of innate immunity. Nat Rev Immunol 2003; 3: 791-800.
9. Javeed A, Zhao Y, Zhao Y. Macrophage-migration inhibitory factor: role in inflammatory diseases and graft rejection. Inflamm Res 2008; 57: 45-50.
10. Flaster H, Bernhagen J, Calandra T, Bucala R. The macrophage migration inhibitory factor-glucocorticoid dyad: regulation of inflammation and immunity. Mol Endocrinol 2007; 21: 1267-1280.
11. Kim HR, Park MK, Cho ML, Yoon CH, Lee SH, Park SH, et al. Macrophage migration inhibitory factor upregulates angiogenic factors and correlates with clinical measures in rheumatoid arthritis. J Rheumatol 2007; 34: 927-936.
12. Hoi AY, Hickey MJ, Hall P, Yamana J, O'Sullivan KM, Santos LL, et al. Macrophage migration inhibitory factor deficiency attenuates macrophage recruitment, glomerulonephritis, and lethality in mrl/lpr mice. J Immunol 2006; 177: 5687-5696.
13. Ishiguro Y, Ohkawara T, Sakuraba H, Yamagata K, Hiraga H, Yamaguchi S, et al. Macrophage migration inhibitory factor has a proinflammatory activity via the p38 pathway in glucocorticoid-resistant ulcerative colitis. Clin Immunol 2006; 120: 335-341.
14. Burger-Kentischer A, Gobel H, Kleemann R, Zernecke A, Bucala R, Leng L, et al. Reduction of the aortic inflammatory response in spontaneous atherosclerosis by blockade of macrophage migration inhibitory factor (MIF). J Atherosclerosis 2006; 184: 28-38.
15. Calandra T, Echtenacher B, Roy DL, Pugin J, Metz CN, Hultner LH, et al. Protection from septic shock by neutralization of macrophage migration inhibitory factor. Nat Med 2000; 6: 164-170.
16. Matsui Y, Okamoto H, Jia N, Akino M, Uede T, Kitabatake A, et al. Blockade of macrophage migration inhibitory factor ameliorates experimental autoimmune myocarditis. J Mol Cel Cardiol 2004; 37: 557-566.
17. Zhao L, Li S, Ge J, Sun A, Zou Y, Zhang S. Temporal changes in stem cells in the circulation and myocardium of mice with Coxsackie virus B3-induced myocarditis. Mcrovasc Res 2008; 75: 358-366.
18. Zhang ZC, Li SJ, Yang YZ, Chen RZ, Ge JB, Chen HZ. Mcroarray analysis of extracellular matrix genes expression in myocardium of mouse with Coxsackie virus B3 myocarditis. Chin Med J 2004; 117: 1228-1231.
19. Cheung C, Marchant D, Walker EK, Luo Z, Zhang J, Yanagawa B, et al. Ablation of matrix metalloproteinase-9 increases severity of viral myocarditis in mice. Circulation 2008; 117: 1574-1582.
20. Kishimoto C, Kawamata H, Sakai S, Shinohara H, Ochiai H. Enhanced production of macrophage inflammatory protein 2 (MIP-2) by in vitro and in vivo infections with encephalomyocarditis virus and modulation of myocarditis with an antibody against MIP-2. J Virol 2001; 75: 1294-1300.
21. Kawai C. From myocarditis to cardiomyopathy: mechanisms of inflammation and cell death. Circulation 1999; 99: 1091-1100.
22. Wong BL, Zhu SL, Huang XR, Ma J, Xia HH, Bucala R, et al. Essential role for macrophage migration inhibitory factor in gastritis induced by Helicobacter pylori. Am J Pathol 2009; 174: 1319-1328.
23. Liu PP, Mason JW. Advances in the understanding of myocarditis. Circulation 2001; 104: 1076-1082.
24. Matsumori A, Yamada T, Suzuki H, Matoba Y, Sasayama S. Increased circulating cytokines in patients with myocarditis and cardiomyopathy. Br Heart J 1994; 72: 561-566.
25. Huber SA, Sartini D. Roles of tumor necrosis factor alpha (TNF-a) and the p55 TNF receptor in CD1d induction and coxsackievirus B3-induced myocarditis. J Virol 2005; 79: 2659-2665.
26. Seko Y, Takahashi N, Yagita H, Okumura K, Yazaki Y Expression of cytokine mRNAs in murine hearts with acute myocarditis caused by coxsackievirus b3. J Pathol 1997; 183: 105-108.
27. Gadjeva M, Nagashima J, Zaidi T, Mtchell RA, Pier GB. Inhibition of macrophage migration inhibitory factor ameliorates ocular Pseudomonas aeruginosa-induced keratitis. PLoS Pathog 2010; 6: e1000826.
28. Lan HY, Yang N, Nikolic-Paterson DJ, Yu XQ, Mu W, Isbel NM, et al. Expression of macrophage migration inhibitory factor in human glomerulonephritis. Kidney Int 2000; 57: 499-509.