Characterization of Streptomyces padanus JAU4234, a producer of actinomycin X2, fungichromin, and a new polyene macrolide antibiotic

Applied and Environmental Microbiology

Volumn 78, Issue 2, 2012, Pages 589-592

  Xiong, Zhi Qiang ^b   Zhang, Zhi Ping ^a   Li, Jiang Huai ^a   Wei, Sai Jin ^a   Tu, Guo Quan ^a  

^a JIANGXI AGRICULTURAL UNIVERSITY   (China)

^b INSTITUTE OF PLANT PHYSIOLOGY AND ECOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-FUNGAL ACTIVITY; CLINICAL APPLICATION; JIANGXI PROVINCE; POLYENE MACROLIDE;

BACTERIA;

ANTIBIOTICS;

ACTINOMYCIN X; ANTIFUNGAL AGENT; BACTERIAL DNA; DACTINOMYCIN; DRUG DERIVATIVE; FUNGICHROMIN; MACROLIDE; POLYENE; RIBOSOME DNA; RNA 16S;

AGROCHEMICAL; ANTIBIOTICS; ANTIMICROBIAL ACTIVITY; BACTERIUM; BIOLOGICAL PRODUCTION; MEDICINE; PEPTIDE; SOIL MICROORGANISM;

ARTICLE; CHEMISTRY; CHINA; CLASSIFICATION; CLUSTER ANALYSIS; DNA SEQUENCE; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYLOGENY; STREPTOMYCES;

ANTIFUNGAL AGENTS; CHINA; CLUSTER ANALYSIS; DACTINOMYCIN; DNA, BACTERIAL; DNA, RIBOSOMAL; MACROLIDES; MOLECULAR SEQUENCE DATA; PHYLOGENY; POLYENES; RNA, RIBOSOMAL, 16S; SEQUENCE ANALYSIS, DNA; SOIL MICROBIOLOGY; STREPTOMYCES;

CHINA; JIANGXI;

STREPTOMYCES PADANUS;

EID: 84862916430     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.06561-11     Document Type: Article

References (18)

1. Bentley SD, et al. 2002. Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature 417:141-147.
2. Bérdy J. 2005. Bioactive microbial metabolites. J. Antibiot. 58:1-26.
3. Cope AC, Johnson HE. 1958. Fungichromin. Determination of the structure of the pentaene chromophore. J. Am. Chem. Soc. 80:1504-1506.
4. Frey Tirri B, Bitzer J, Geudelin B, Drewe J. 2010. Safety, tolerability and pharmacokinetics of intravaginal pentamycin. Chemotherapy 56: 190-196.
5. 13carbon-labeled octanoate into fungichromin by Streptomyces cellulosae. J. Am. Chem. Soc. 108:3833-3834.
6. Kumarasamy KK, Toleman MA, Walsh TR. 2010. Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. Lancet Infect. Dis. 10: 597-602.
7. 2-producer. Appl. Microbiol. Biotechnol. 72:145-154.
8. Mirau PA, Shafer RH. 1982. High-resolution proton nuclear magnetic resonance analysis of conformational properties of biosynthetic actinomycin analogues. Biochemistry 21:2622-2626.
9. Mulks MH, Nair MG, Putnam AR. 1990. In vitro antibacterial activity of faeriefungin, a new broad-spectrum polyene macrolide antibiotic. Antimicrob. Agents Chemother. 34:1762-1765.
10. Noguchi H, et al. 1988. Biosynthesis and full NMR assignment of fungichromin, a polyene antibiotic fromStreptomyces cellulose. J. Am. Chem. Soc. 110:2938-2945.
11. Rahman H, et al. 2010. Novel anti-infective compounds from marine bacteria. Mar. Drugs 8:498-518.
12. Shih HD, et al. 2003. Fungichromin: a substance from Streptomyces padanus with inhibitory effects on Rhizoctonia solani. J. Agric. Food Chem. 51:95-99.
13. Shimizu M, Igarashi Y, Furumai T, Onaka H, Kunoh H. 2004. Identication of endophytic Streptomyces sp. R-5 and analysis of its antimicrobial metabolites. J. Gen. Plant Pathol. 70:66-68.
14. Sun Y, et al. 2003. A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin. Chem. Biol. 10:431-441.
15. Sun Y, et al. 2002. 'Streptomyces nanchangensis', a producer of the insec-ticidal polyether antibiotic nanchangmycin and the antiparasitic macrolide meilingmycin, containsmultiple polyketide gene clusters. Microbiology 148:361-371.
16. Sun Y, Zhou X, Tu G, Deng Z. 2003. Identication of a gene cluster encodingmeilingmycin biosynthesis amongmultiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226. Arch. Microbiol. 180:101-107.
17. Umezawa S, Tanaka Y, Ooka M, Shiotsu S. 1958. A new antifungal antibiotic, pentamycin. J. Antibiot. 11:26-29.
18. Zhang C, et al. 2008. Isolation, structure, and antibacterial activity of philipimycin, a thiazolyl peptide discovered from Actinoplanes philippinensis MA7347. J. Am. Chem. Soc. 130:12102-12110.