Identification of cancer stem cell-related micrornas in hepatocellular carcinoma

Methods in Molecular Biology

Volumn 826, Issue , 2012, Pages 163-175

  Ji, Junfang ^a   Wang, Xin Wei ^a  

^a Laboratory of Human Carcinogenesis   (United States)

Author keywords

EpCAM; Fluorescence activated cell sorting; Hepatic cancer stem cells; Hepatocellular carcinoma; MicroRNA microarray; MicroRNAs; Quantitative reverse transcription polymerase chain reaction; Spheroid assay; Transfection; Tumorigenicity assay

Indexed keywords

CELL ADHESION MOLECULE; MICRORNA; TUMOR ANTIGEN; TUMOR ASSOCIATED ANTIGEN GA733; TUMOR-ASSOCIATED ANTIGEN GA733;

ANIMAL; ARTICLE; CANCER STEM CELL; CARCINOGEN TESTING; DNA MICROARRAY; FLOW CYTOMETRY; GENETIC TRANSFECTION; GENETICS; HUMAN; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; MOUSE; MOUSE MUTANT; MULTICELLULAR SPHEROID; NONOBESE DIABETIC MOUSE; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

ANIMALS; ANTIGENS, NEOPLASM; CARCINOGENICITY TESTS; CARCINOMA, HEPATOCELLULAR; CELL ADHESION MOLECULES; CELL LINE, TUMOR; FLOW CYTOMETRY; HUMANS; LIVER NEOPLASMS; MICE; MICE, INBRED NOD; MICE, SCID; MICRORNAS; NEOPLASTIC STEM CELLS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPHEROIDS, CELLULAR; TRANSFECTION;

EID: 84862909343     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-468-1_14     Document Type: Article

References (31)

1. Gupta PB, Chaffer CL, and Weinberg RA (2009) Cancer stem cells:mirage or reality? Nat. Med 15 : 1010-1012
2. Al Hajj M, Wicha MS, Benito-Hernandez A et al (2003) Prospective identifi cation of tumorigenic breast cancer cells. Proc. Natl. Acad. Sci USA 100 : 3983-3988 (Pubitemid 36418143)
3. Singh SK, Hawkins C, Clarke ID et al (2004) Identifi cation of human brain tumour initiating cells. Nature 432 : 396-401 (Pubitemid 39551674)
4. Bonnet D. and Dick JE (1997) Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat. Med. 3 : 730-737 (Pubitemid 27298715)
5. Ricci-Vitiani L, Lombardi DG, Pilozzi E et al (2007) Identifi cation and expansion of human colon-cancer-initiating cells. Nature 445 : 111-115 (Pubitemid 46067311)
6. O'Brien CA, Pollett A, Gallinger S et al (2007) A human colon cancer cell capable of initiating tumour growth in immunodefi cient mice. Nature 445 : 106-110 (Pubitemid 46067310)
7. Yamashita T, Ji J, Budhu A et al (2009) EpCAMpositive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features. Gastroenterology 136 : 1012-1024
8. Parkin DM, Bray F, Ferlay J et al (2005) Global cancer statistics, 2002. CA Cancer J. Clin 55 : 74-108
9. Yang ZF, Ho DW, Ng MN et al (2008) Signifi cance of CD90(+) Cancer Stem Cells in Human Liver Cancer. Cancer Cell 13 : 153-166 (Pubitemid 351163165)
10. Ma S, Chan KW, Hu L et al (2007) Identifi cation and characterization of tumorigenic liver cancer stem/progenitor cells. Gastroenterology 132 : 2542-2556 (Pubitemid 46890873)
11. Yamashita T, Forgues M, Wang W et al (2008) EpCAM and alpha-fetoprotein expression defi nes novel prognostic subtypes of hepatocellular carcinoma. Cancer Res. 68 : 1451-1461 (Pubitemid 351346853)
12. Lagos-Quintana M, Rauhut R, Lendeckel W et al (2001) Identifi cation of novel genes coding for small expressed RNAs. Science 294 : 853-858 (Pubitemid 33032103)
13. Lau NC, Lim LP, Weinstein EG et al (2001) An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294 : 858-862 (Pubitemid 33032104)
14. Ji J, Yamashita T, Budhu A et al (2009) Identifi cation of microRNA-181 by genomewide screening as a critical player in EpCAMpositive hepatic cancer stem cells. Hepatology 50 : 472-480
15. Ji J, Shi J, Budhu A et al (2009) MicroRNA expression, survival, and response to interferon in liver cancer. N. Engl. J Med 361 : 1437-1447
16. Ji J. and Wang X.W (2009) New kids on the block:Diagnostic and prognostic microRNAs in hepatocellular carcinoma. Cancer Biol Ther. 8:1686-1693
17. Budhu A, Jia HL, Forgues M et al (2008) Identifi cation of metastasis-related microRNAs in hepatocellular carcinoma. Hepatology 47 : 897-907 (Pubitemid 351449681)
18. Lu J, Getz G, Miska EA et al (2005) MicroRNA expression profi les classify human cancers. Nature 435 : 834-838 (Pubitemid 40839735)
19. Croce CM. and Calin GA (2005) miRNAs, cancer, and stem cell division. Cell 122 : 6-7 (Pubitemid 40977933)
20. Rogler CE, Levoci L, Ader T et al (2009) MicroRNA-23b cluster microRNAs regulate transforming growth factor-beta/bone morphogenetic protein signaling and liver stem cell differentiation by targeting Smads. Hepatology 50 : 575-584
21. Hatfi eld SD, Shcherbata HR, Fischer KA et al (2005) Stem cell division is regulated by the microRNA pathway. Nature 435 : 974-978 (Pubitemid 40896325)
22. Bernstein E, Kim SY, Carmell MA et al (2003) Dicer is essential for mouse development. Nat. Genet. 35 : 215-217
23. Strauss WM, Chen C, Lee CT et al (2006) Nonrestrictive developmental regulation of microRNA gene expression. Mamm. Genome 17 : 833-840 (Pubitemid 44232580)
24. Suh MR, Lee Y, Kim JY et al (2004) Human embryonic stem cells express a unique set of microRNAs. Dev. Biol. 270 : 488-498 (Pubitemid 38748567)
25. Chen CZ, Li L, Lodish HF et al (2004) MicroRNAs modulate hematopoietic lineage differentiation. Science 303: 83-86 (Pubitemid 38055775)
26. Schratt GM, Tuebing F, Nigh EA et al (2006) A brain-specifi c microRNA regulates dendritic spine development. Nature 439: 283-289 (Pubitemid 43128846)
27. Yi R, Poy MN, Stoffel M et al (2008) A skin microRNA promotes differentiation by repressing 'stemness'. Nature 452: 225-229
28. Kota J, Chivukula RR, O'donnell KA et al z(2009) Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 137: 1005-1017
29. Liu CG, Calin GA, Meloon B et al (2004) An oligonucleotide microchip for genomewide microRNA profiling in human and mouse tissues. Proc Natl Acad Sci USA 101: 9740-9744 (Pubitemid 38869306)
30. Voorhoeve PM, le Sage C, Schrier M et al (2006) A genetic screen implicates miRNA- 372 and miRNA-373 as oncogenes in testicular germ cell tumors. Cell 124: 1169-1181
31. Krutzfeldt J, Rajewsky N, Braich R et al (2005) Silencing of microRNAs in vivo with 'antagomirs'. Nature 438: 685-689