Lutein and zeaxanthin supplementation reduces H 2O 2-induced oxidative damage in human lens epithelial cells

Molecular Vision

Volumn 17, Issue , 2011, Pages 3180-3190

  Gao, Shasha ^a,b   Qin, Tingyu ^b   Liu, Zhenzhen ^a,b   Caceres, Maria Andrea ^b   Ronchi, Carlos F ^b   Oliver Chen, C Y ^b   Yeum, Kyung Jin ^b   Taylor, Allen ^b   Blumberg, Jeffery B ^b   Liu, Yizhi ^a   Shang, Fu ^b  

^a SUN YAT SEN UNIVERSITY   (China)

^b TUFTS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DINITROPHENYLHYDRAZINE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ALPHA TOCOPHEROL; CARBONYL DERIVATIVE; DNA; GLUTATHIONE; GLUTATHIONE DISULFIDE; HYDROGEN PEROXIDE; LIPID; MALONALDEHYDE; XANTHOPHYLL; ZEAXANTHIN;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL VIABILITY; COMET ASSAY; CONTROLLED STUDY; DIET SUPPLEMENTATION; DNA DAMAGE; EPITHELIUM CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INCUBATION TIME; LENS EPITHELIUM; LIPID OXIDATION; LIPID PEROXIDATION; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; WESTERN BLOTTING;

ALPHA-TOCOPHEROL; BLOTTING, WESTERN; CATARACT; CELL SURVIVAL; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMET ASSAY; DIETARY SUPPLEMENTS; DNA DAMAGE; EPITHELIAL CELLS; GLUTATHIONE; HUMANS; HYDROGEN PEROXIDE; LENS, CRYSTALLINE; LIPID PEROXIDATION; LUTEIN; MALONDIALDEHYDE; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEIN CARBONYLATION; XANTHOPHYLLS;

EID: 84862907747     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Resnikoff S, Pascolini D, Etya'ale D, Kocur I, Pararajasegaram R, Pokharel GP, Mariotti SP. Global data on visual impairment in the year 2002. Bull World Health Organ 2004; 82:844-51. [PMID: 15640920]
2. Stark WJ, Sommer A, Smith RE. Changing trends in intraocular lens implantation. Arch Ophthalmol 1989; 107:1441-4. [PMID: 2803089]
3. Mares-Perlman JA, Brady WE, Klein BE, Klein R, Palta M, Bowen P, Stacewicz-Sapuntzakis M. Serum carotenoids and tocopherols and severity of nuclear and cortical opacities. Invest Ophthalmol Vis Sci 1995; 36:276-88. [PMID: 7843899]
4. Moeller SM, Voland R, Tinker L, Blodi BA, Klein ML, Gehrs KM, Johnson EJ, Snodderly DM, Wallace RB, Chappell RJ, Parekh N, Ritenbaugh C, Mares JA. Associations between age-related nuclear cataract and lutein and zeaxanthin in the diet and serum in the Carotenoids in the Age-Related Eye Disease Study, an Ancillary Study of the Women's Health Initiative. Arch Ophthalmol 2008; 126:354-64. [PMID: 18332316]
5. Chiu CJ, Taylor A. Nutritional antioxidants and age-related cataract and maculopathy. Exp Eye Res 2007; 84:229-45. [PMID: 16879819]
6. Vu HT, Robman L, Hodge A, McCarty CA, Taylor HR. Lutein and zeaxanthin and the risk of cataract: the Melbourne visual impairment project. Invest Ophthalmol Vis Sci 2006; 47:3783-6. [PMID: 16936087]
7. Christen WG, Liu S, Glynn RJ, Gaziano JM, Buring JE. Dietary carotenoids, vitamins C and E, and risk of cataract in women: a prospective study. Arch Ophthalmol 2008; 126:102-9. [PMID: 18195226]
8. Chasan-Taber L, Willett WC, Seddon JM, Stampfer MJ, Rosner B, Colditz GA, Speizer FE, Hankinson SE. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999; 70:509-16. [PMID: 10500020]
9. Chiu CJ, Taylor A. Nutritional antioxidants, dietary carbohydrates, and age-related maculopathy and cataract. In, Bendich A, Deckelbaum RJ, editors. Preventive Nutrition: The comprehensive guide for health professionals. 4 ed. 2010, Humana Press. p. 501-44.
10. Yeum KJ, Taylor A, Tang G, Russell RM. Measurement of carotenoids, retinoids, and tocopherols in human lenses. Invest Ophthalmol Vis Sci 1995; 36:2756-61. [PMID: 7499098]
11. Yeum KJ, Shang FM, Schalch WM, Russell RM, Taylor A. Fatsoluble nutrient concentrations in different layers of human cataractous lens. Curr Eye Res 1999; 19:502-5. [PMID: 10550792]
12. Spector A. Oxidative stress-induced cataract: mechanism of action. FASEB J 1995; 9:1173-82. [PMID: 7672510]
13. Beebe DC, Holekamp NM, Shui YB. Oxidative damage and the prevention of age-related cataracts. Ophthalmic Res 2010; 44:155-65. [PMID: 20829639]
14. Truscott RJ. Age-related nuclear cataract-oxidation is the key. Exp Eye Res 2005; 80:709-25. [PMID: 15862178]
15. Varma SD, Devamanoharan PS, Morris SM. Prevention of cataracts by nutritional and metabolic antioxidants. Crit Rev Food Sci Nutr 1995; 35:111-29. [PMID: 7748471]
16. Spector A, Wang GM, Wang RR, Li WC, Kleiman NJ. A brief photochemically induced oxidative insult causes irreversible lens damage and cataract. II. Mechanism of action. Exp Eye Res 1995; 60:483-93. [PMID: 7615014]
17. Spector A, Wang GM, Wang RR, Li WC, Kuszak JR. A brief photochemically induced oxidative insult causes irreversible lens damage and cataract. I. Transparency and epithelial cell layer. Exp Eye Res 1995; 60:471-81. [PMID: 7615013]
18. Gupta SK, Trivedi D, Srivastava S, Joshi S, Halder N, Verma SD. Lycopene attenuates oxidative stress induced experimental cataract development: an in vitro and in vivo study. Nutrition 2003; 19:794-9. [PMID: 12921892]
19. Li L, Duker JS, Yoshida Y, Niki E, Rasmussen H, Russell RM, Yeum KJ. Oxidative stress and antioxidant status in older adults with early cataract. Eye (Lond) 2009; 23:1464-8. [PMID: 18806766]
20. Yeum KJ, Aldini G, Chung HY, Krinsky NI, Russell RM. The activities of antioxidant nutrients in human plasma depend on the localization of attacking radical species. J Nutr 2003; 133:2688-91. [PMID: 12888659]
21. Kim SR, Nakanishi K, Itagaki Y, Sparrow JR. Photooxidation of A2-PE, a photoreceptor outer segment fluorophore, and protection by lutein and zeaxanthin. Exp Eye Res 2006; 82:828-39. [PMID: 16364293]
22. Csukas S, Costarides A, Riley MV, Green K. Hydrogen peroxide in the rabbit anterior chamber: effects on glutathione, and catalase effects on peroxide kinetics. Curr Eye Res 1987; 6:1395-402. [PMID: 3427989]
23. Spector A, Garner WH. Hydrogen peroxide and human cataract. Exp Eye Res 1981; 33:673-81. [PMID: 7318962]
24. Bhuyan KC, Bhuyan DK, Podos SM. Lipid peroxidation in cataract of the human. Life Sci 1986; 38:1463-71. [PMID: 3702587]
25. Zigler JS Jr, Huang QL, Du XY. Oxidative modification of lens crystallins by H2O2 and chelated iron. Free Radic Biol Med 1989; 7:499-505. [PMID: 2558979]
26. Shang F, Lu M, Dudek E, Reddan J, Taylor A. Vitamin C and vitamin E restore the resistance of GSH-depleted lens cells to H2O2. Free Radic Biol Med 2003; 34:521-30. [PMID: 12614841]
27. Bruno M, Moore T, Nesnow S, Ge Y. Protein carbonyl formation in response to propiconazole-induced oxidative stress. J Proteome Res 2009; 8:2070-8. [PMID: 19714882]
28. Fukunaga K, Yoshida M, Nakazono N. A simple, rapid, highly sensitive and reproducible quantification method for plasma malondialdehyde by high-performance liquid chromatography. Biomed Chromatogr 1998; 12:300-3. [PMID: 9787903]
29. Harvey PR, Ilson RG, Strasberg SM. The simultaneous determination of oxidized and reduced glutathiones in liver tissue by ion pairing reverse phase high performance liquid chromatography with a coulometric electrochemical detector. Clin Chim Acta 1989; 180:203-12. [PMID: 2743574]
30. Singh NP, McCoy MT, Tice RR, Schneider EL. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 1988; 175:184-91. [PMID: 3345800]
31. Tice RR, Andrews PW, Hirai O, Singh NP. The single cell gel (SCG) assay: an electrophoretic technique for the detection of DNA damage in individual cells. Adv Exp Med Biol 1991; 283:157-64. [PMID: 2068983]
32. Collins AR. The comet assay for DNA damage and repair: principles, applications, and limitations. Mol Biotechnol 2004; 26:249-61. [PMID: 15004294]
33. Braz MG, Favero Salvadori DM. Influence of endogenous and synthetic female sex hormones on human blood cells in vitro studied with comet assay. Toxicol In Vitro 2007; 21:972-6. [PMID: 17412554]
34. Hu Y, Xu Z. Effects of lutein on the growth and migration of bovine lens epithelial cells in vitro. J Huazhong Univ Sci Technolog Med Sci 2008; 28:360-3. [PMID: 18563343]
35. Spector A, Ma W, Wang RR. The aqueous humor is capable of generating and degrading H2O2. Invest Ophthalmol Vis Sci 1998; 39:1188-97. [PMID: 9620079]
36. Ramachandran S, Morris SM, Devamanoharan P, Henein M, Varma SD. Radio-isotopic determination of hydrogen peroxide in aqueous humor and urine. Exp Eye Res 1991; 53:503-6. [PMID: 1936185]
37. Devamanoharan PS, Ramachandran S, Varma SD. hydrogen peroxide in the eye lens: radioisotopic determination. Curr Eye Res 1991; 10:831-8. [PMID: 1790713]
38. Dudek EJ, Shang F, Taylor AH. (2)O(2)-mediated oxidative stress activates NF-kappa B in lens epithelial cells. Free Radic Biol Med 2001; 31:651-8. [PMID: 11522450]
39. Davies MJ, Truscott RJ. Photo-oxidation of proteins and its role in cataractogenesis. J Photochem Photobiol B 2001; 63:114-25. [PMID: 11684458]
40. Harding JJ. Viewing molecular mechanisms of ageing through a lens. Ageing Res Rev 2002; 1:465-79. [PMID: 12067598]
41. Beckman KB, Ames BN. The free radical theory of aging matures. Physiol Rev 1998; 78:547-81. [PMID: 9562038]
42. Spector A, Wang GM, Wang RR, Garner WH, Moll H. The prevention of cataract caused by oxidative stress in cultured rat lenses. I. H2O2 and photochemically induced cataract. Curr Eye Res 1993; 12:163-79. [PMID: 8383589]
43. Bates CJ, Chen SJ, Macdonald A, Holden R. Quantitation of vitamin E and a carotenoid pigment in cataractous human lenses, and the effect of a dietary supplement. Internationale Zeitschrift fur Vitamin-und Ernahrungsforschung 1996; 66:316-21. [PMID: 8979159]
44. Krinsky NI, Landrum JT, Bone RA. Biologic mechanisms of the protective role of lutein and zeaxanthin in the eye. Annu Rev Nutr 2003; 23:171-201. [PMID: 12626691]
45. Bone RA, Landrum JT. Dose-dependent response of serum lutein and macular pigment optical density to supplementation with lutein esters. Arch Biochem Biophys 2010; 504:50-5. [PMID: 20599660]
46. Calvin HI, von Hagen S, Hess JL, Patel SA, Fu SC. Lens GSH depletion and electrolyte changes preceding cataracts induced by buthionine sulfoximine in suckling mice. Exp Eye Res 1992; 54:621-6. [PMID: 1623947]
47. Giblin FJ. Glutathione: a vital lens antioxidant. J Ocul Pharmacol Ther 2000; 16:121-35. [PMID: 10803423]
48. Rikans LE, Moore DR. Effect of aging on aqueous-phase antioxidants in tissues of male Fischer rats. Biochim Biophys Acta 1988; 966:269-75. [PMID: 3416012]
49. Chen TS, Richie JP Jr, Lang CA. Life span profiles of glutathione and acetaminophen detoxification. Drug Metab Dispos 1990; 18:882-7. [PMID: 1981532]
50. Yu NT, DeNagel DC, Pruett PL, Kuck JF Jr. Disulfide bond formation in the eye lens. Proc Natl Acad Sci USA 1985; 82:7965-8. [PMID: 3865209]
51. Lou MF. Thiol regulation in the lens. J Ocul Pharmacol Ther 2000; 16:137-48. [PMID: 10803424]
52. Masaki H, Okano Y, Ochiai Y, Obayashi K, Akamatsu H, Sakurai H. alpha-tocopherol increases the intracellular glutathione level in HaCaT keratinocytes. Free Radic Res 2002; 36:705-9. [PMID: 12180196]
53. Costagliola C, Iuliano G, Menzione M, Rinaldi E, Vito P, Auricchio G. Effect of vitamin E on glutathione content in red blood cells, aqueous humor and lens of humans and other species. Exp Eye Res 1986; 43:905-14. [PMID: 3817031]