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Volumn 77, Issue , 2012, Pages 105-111

In-situ monitoring and characterization of plug flow crystallizers

Author keywords

Crystallization; Multiphase flow; Particulate processes; Pharmaceuticals; Process analytical technology; Static mixer

Indexed keywords

ANALYTICAL TECHNOLOGY; ANTI-SOLVENTS; AQUEOUS ETHANOL SOLUTIONS; ATR FTIR; BATCH OPERATION; BENZOIC ACID; CHORD LENGTHS; CONCENTRATION MONITORING; FEED CONCENTRATION; FLOW CELLS; IN-SITU; IN-SITU MONITORING; MIXING EFFICIENCY; MIXING TIME; PARTICULATE PROCESS; PLUG FLOW; PROCESS ANALYTICAL TECHNOLOGY; PRODUCT SIZES; RELATIVE FLOW; STATIC MIXERS; TUBULAR REACTORS; VORTEX MIXERS;

EID: 84862898861     PISSN: 00092509     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ces.2012.02.013     Document Type: Article
Times cited : (65)

References (18)
  • 1
    • 77952016461 scopus 로고    scopus 로고
    • Continuous plug flow crystallization of pharmaceutical compounds
    • Alvarez A.J., Myerson A. Continuous plug flow crystallization of pharmaceutical compounds. Cryst. Growth Des. 2010, 10:2219-2228.
    • (2010) Cryst. Growth Des. , vol.10 , pp. 2219-2228
    • Alvarez, A.J.1    Myerson, A.2
  • 2
    • 49549106798 scopus 로고    scopus 로고
    • Reactive Crystallization Method to Improve Particle Size
    • U.S. Patent 6,558,435, May 6.
    • Am Ende, D.J., Crawford, T.C., Weston, N.P., 2003. Reactive Crystallization Method to Improve Particle Size. U.S. Patent 6,558,435, May 6.
    • (2003)
    • Am Ende, D.J.1    Crawford, T.C.2    Weston, N.P.3
  • 3
    • 77955359115 scopus 로고    scopus 로고
    • Supersaturation tracking for the development, optimization and control of crystallization processes
    • Barrett M., McNamara M., Hao H., Barrett P., Glennon B. Supersaturation tracking for the development, optimization and control of crystallization processes. Chem. Eng. Res. Des. 2010, 88:1108-1119.
    • (2010) Chem. Eng. Res. Des. , vol.88 , pp. 1108-1119
    • Barrett, M.1    McNamara, M.2    Hao, H.3    Barrett, P.4    Glennon, B.5
  • 4
    • 0034745813 scopus 로고    scopus 로고
    • Kinetics identification of salicylic acid precipitation through experiments in a batch stirred vessel and a T-mixer
    • Blandin A.F., Mangin D., Vallet V., Klein J.P., Bossoutrot J.M. Kinetics identification of salicylic acid precipitation through experiments in a batch stirred vessel and a T-mixer. Chem. Eng. J. 2001, 81:91-100.
    • (2001) Chem. Eng. J. , vol.81 , pp. 91-100
    • Blandin, A.F.1    Mangin, D.2    Vallet, V.3    Klein, J.P.4    Bossoutrot, J.M.5
  • 5
    • 0040284062 scopus 로고    scopus 로고
    • Dual Jet Crystallizer Apparatus
    • U.S. Patent 5,578,279, November 26.
    • Dauer, R., Mokrauer, J.E., McKeel, W.J., 1996. Dual Jet Crystallizer Apparatus. U.S. Patent 5,578,279, November 26.
    • (1996)
    • Dauer, R.1    Mokrauer, J.E.2    McKeel, W.J.3
  • 6
    • 0141513754 scopus 로고    scopus 로고
    • Investigation of impinging jet crystallization with a calcium. Oxalate model system
    • Hacherl J.M., Paul E.L., Buettner H.M. Investigation of impinging jet crystallization with a calcium. Oxalate model system. AIChE J. 2003, 49:2352-2362.
    • (2003) AIChE J. , vol.49 , pp. 2352-2362
    • Hacherl, J.M.1    Paul, E.L.2    Buettner, H.M.3
  • 7
    • 0141848427 scopus 로고    scopus 로고
    • Chemical processing and micromixing in confined impinging jets
    • Johnson B.K., Prud'Homme R.K. Chemical processing and micromixing in confined impinging jets. AIChE J. 2003, 49:2264-2282.
    • (2003) AIChE J. , vol.49 , pp. 2264-2282
    • Johnson, B.K.1    Prud'Homme, R.K.2
  • 8
    • 47849131955 scopus 로고    scopus 로고
    • Experimental characterization and multi-scale modeling of mixing in static mixers
    • Brozio
    • Lindenberg C., Schöll J., Vicum L., Mazzotti M., Brozio Experimental characterization and multi-scale modeling of mixing in static mixers. Chem. Eng. Sci. 2008, 63:4135-4148.
    • (2008) Chem. Eng. Sci. , vol.63 , pp. 4135-4148
    • Lindenberg, C.1    Schöll, J.2    Vicum, L.3    Mazzotti, M.4
  • 9
    • 84862899481 scopus 로고    scopus 로고
    • Optimizing the Precipitation of Organic Compounds
    • PhD Thesis, Swiss Federal Institute of Technology, Zurich.
    • Lindenberg, C., 2009. Optimizing the Precipitation of Organic Compounds. PhD Thesis, Swiss Federal Institute of Technology, Zurich.
    • (2009)
    • Lindenberg, C.1
  • 10
    • 68949098389 scopus 로고    scopus 로고
    • Experimental characterization and multi-scale modeling of mixing in static mixers. Part 2. Effect of viscosity and scale-up
    • Lindenberg C., Mazzotti M. Experimental characterization and multi-scale modeling of mixing in static mixers. Part 2. Effect of viscosity and scale-up. Chem. Eng. Sci. 2009, 64(20):4286-4294.
    • (2009) Chem. Eng. Sci. , vol.64 , Issue.20 , pp. 4286-4294
    • Lindenberg, C.1    Mazzotti, M.2
  • 11
    • 49549123484 scopus 로고    scopus 로고
    • Sonic Impinging Jet Apparatus and Process
    • US Patent 6,302,958, October 16.
    • Linrud, M.D., Kim, S., Wei, C., 2001. Sonic Impinging Jet Apparatus and Process. US Patent 6,302,958, October 16.
    • (2001)
    • Linrud, M.D.1    Kim, S.2    Wei, C.3
  • 12
    • 43049174741 scopus 로고    scopus 로고
    • Mixing in a multi-inlet vortex mixer (MIVM) for flash nano-precipitation
    • Liu Y., Cheng C.Y., Liu Y., Prud'homme R.K., Fox R.O. Mixing in a multi-inlet vortex mixer (MIVM) for flash nano-precipitation. Chem. Eng. Sci. 2008, 63:2829-2842.
    • (2008) Chem. Eng. Sci. , vol.63 , pp. 2829-2842
    • Liu, Y.1    Cheng, C.Y.2    Liu, Y.3    Prud'homme, R.K.4    Fox, R.O.5
  • 13
    • 0030199439 scopus 로고    scopus 로고
    • Micromixing effects in a two-impinging-jets precipitator
    • Mahajan A.J., Kirwan D.J. Micromixing effects in a two-impinging-jets precipitator. AIChE J. 1996, 42:1801-1814.
    • (1996) AIChE J. , vol.42 , pp. 1801-1814
    • Mahajan, A.J.1    Kirwan, D.J.2
  • 14
    • 33646360561 scopus 로고    scopus 로고
    • Design and scale-up of chemical reactors for nanoparticle precipitation
    • Marchisio D.L., Rivautella L., Barresi A.A. Design and scale-up of chemical reactors for nanoparticle precipitation. AIChE J. 2006, 52:1877-1887.
    • (2006) AIChE J. , vol.52 , pp. 1877-1887
    • Marchisio, D.L.1    Rivautella, L.2    Barresi, A.A.3
  • 15
    • 0039692357 scopus 로고
    • A Crystallization Method to Improve Structure and Size
    • European Patent 91305432.6.
    • Middler, M.J., Liu, P.D., Paul, E.L., Futran, M., Whittington, E.F., 1991. A Crystallization Method to Improve Structure and Size. European Patent 91305432.6.
    • (1991)
    • Middler, M.J.1    Liu, P.D.2    Paul, E.L.3    Futran, M.4    Whittington, E.F.5
  • 18
    • 0038488800 scopus 로고    scopus 로고
    • Reaction crystallization kinetics of benzoic acid
    • Ståhl M., Åslund B.L., Rasmuson Å.C. Reaction crystallization kinetics of benzoic acid. AIChE J. 2001, 47:1544-1560.
    • (2001) AIChE J. , vol.47 , pp. 1544-1560
    • Ståhl, M.1    Åslund, B.L.2    Rasmuson Å, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.