Supersaturation tracking for the development, optimization and control of crystallization processes

Chemical Engineering Research and Design

Volumn 88, Issue 8, 2010, Pages 1108-1119

  Barrett, Mark ^a   McNamara, Mairtin ^a   Hao, HongXun ^a   Barrett, Paul ^b   Glennon, Brian ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

ATR FTIR; Crystallization; FBRM; Feedback control; Scale up; Supersaturation

Indexed keywords

ACTIVE PHARMACEUTICAL INGREDIENTS; ATR-FTIR; BATCH CRYSTALLIZATION; BENZOIC ACID; COOLING CRYSTALLIZATION; CYCLE TIME; DESIGN AND OPTIMIZATION; DRIVING FORCES; IN-SITU; NUCLEATION AND GROWTH KINETICS; OPTIMIZATION AND CONTROL; PHYSICAL MECHANISM; PROCESS CONTROL STRATEGIES; PROCESS UNDERSTANDING; SCALE-UP; SOLUTE SOLUBILITY;

AGGLOMERATION; CRYSTALLIZATION; DISSOLUTION; DRUG PRODUCTS; FEEDBACK CONTROL; GROWTH KINETICS; OPTIMIZATION; SUPERSATURATION;

PROCESS CONTROL;

EID: 77955359115     PISSN: 02638762     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cherd.2010.02.010     Document Type: Article

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