Role of a neural cell adhesion molecule found in cerebrospinal fluid as a potential biomarker for epilepsy

Neurochemical Research

Volumn 37, Issue 4, 2012, Pages 819-825

  Wang, Wei ^a   Wang, Liang ^b   Luo, Jing ^b   Xi, Zhiqin ^b   Wang, Xuefeng ^b   Chen, Guojun ^b   Chu, Lan ^a  

^a GUIZHOU MEDICAL UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Biomarker; Cerebrospinal fluid; ELISA; Epilepsy; NCAM 1; Serum

Indexed keywords

BIOLOGICAL MARKER; NERVE CELL ADHESION MOLECULE;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CONTROLLED STUDY; DISEASE CLASSIFICATION; DRUG EFFECTIVE EPILEPSY; DRUG REFRACTORY EPILEPSY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPILEPSY; FEMALE; FIRST DIAGNOSIS EPILEPSY; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN CEREBROSPINAL FLUID LEVEL; SCHOOL CHILD;

ADOLESCENT; ADULT; AGED; ANTIGENS, CD56; BIOLOGICAL MARKERS; CHILD; EPILEPSY; FEMALE; HUMANS; MALE; MIDDLE AGED; YOUNG ADULT;

EID: 84862894176     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-011-0677-x     Document Type: Article

References (47)

1. Löscher W, Klotz U, Zimprich F et al (2009) The clinical impact of pharmacogenetics on the treatment of epilepsy. Epilepsia 50:1-23
2. Sander JW, Shorvon SD (1996) Epidemiology of the epilepsies. J Neurol Neurosurg Psychiatr 61:433-443 (Pubitemid 26394897)
3. Liu CC, Pardalos PM, Chaovalitwongse WA et al (2008) Quantitative complexity analysis in multi-channel intracranial EEG recordings form epilepsy brains. J Comb Optim 15:276-286
4. Hui AC, Kwan P, Leung TW et al (2007) Diagnostic value and safety of long-term video-EEG monitoring. Hong Kong Med J 13:228-230 (Pubitemid 46911669)
5. Jack CR Jr (1996) Magnetic resonance imaging in epilepsy. Mayo Clin Proc 71:695-711 (Pubitemid 126765410)
6. Choi JY, Kim SJ, Hong SB et al (2003) Extratemporal hypometabolism on FDG PET in temporal lobe epilepsy as a predictor of seizure outcome after temporal lobectomy. Eur J Nucl Med Mol Imaging 30:581-587 (Pubitemid 36559837)
7. Deblaere K, Backes WH, Hofman P et al (2002) Developing a comprehensive presurgical functional MRI protocol for patients with intractable temporal lobe epilepsy: a pilot study. Neuroradiology 44:667-673 (Pubitemid 36075929)
8. Smith D, Defalla BA, Chadwick DW et al (1999) The misdiagnosis of epilepsy and the management of refractory epilepsy in a specialist clinic. QJM-INT J Med 92:15-23 (Pubitemid 29034096)
9. Benbadis S (2009) The differential diagnosis of epilepsy: a critical review. Epilepsy Behav 15:15-21
10. Wang L, Pan Y, Xiao Z et al (2010) Tetranectin is a potential biomarker in cerebrospinal fluid and serum of patients with epilepsy. Clin Chim Acta 411:581-583
11. Xiao Z, Shen L, Wang L, Wang X et al (2010) Talin 2 concentrations in cerebrospinal fluid in patients with epilepsy. Clin Biochem 43:1129-1132
12. Xiao F, Chen D, Lu Y, Wang X et al (2009) Proteomic analysis of cerebrospinal fluid from patients with idiopathic temporal lobe epilepsy. Brain Res 1255:180-189
13. Lin T, Wang X, Zeng Y et al (2008) The expression of NCAM-140 kDa in temporal lobe neocortex of patients with intractable epilepsy: the relation between the plasticity of temporal lobe neocortex and in tractable epilepsy. Zhong Feng Yu Shen Jing Ji Bing Za Zhi 25:305-308
14. Gnanapavan S, Grant D, Illes-Toth E et al (2010) Neural cell adhesion molecule-description of a CSF ELISA method and evidence of reduced levels in selected neurological disorders. J Neuroimmunol 225:118-122
15. Massaro AR, De Pascalis D, Carnevale A et al (2009) The neural cell adhesion molecule (NCAM) present in the cerebrospinal fluid of multiple sclerosis patients is unsialylated. Eur Rev Med Pharmacol Sci 13:397-399
16. Massaro AR (2002) The role of NCAM in remyelination. Neurol Sci 22:429-435 (Pubitemid 34436805)
17. Vawter MP, Frye MA, Hemperly JJ et al (2000) Elevated concentration of N-CAM VASE isoforms in schizophrenia. J Psychiatr Res 34:25-34 (Pubitemid 30006938)
18. Vawter MP (2000) Dysregulation of the neural cell adhesion molecule and neuropsychiatric disorders. Eur J Pharmacol 405:385-395
19. Poltorak M, Frye MA, Wright R et al (1996) Increased neural cell adhesion molecule in the CSF of patients with mood disorder. J Neurochem 66:1532-1538 (Pubitemid 26090556)
20. van Kammen DP, Poltorak M, Kelley ME et al (1998) Further studies of elevated cerebrospinal fluid neuronal cell adhesion molecule in schizophrenia. Biol Psychiatr 43:680-686 (Pubitemid 28222389)
21. Seino M (2006) Classification criteria of epileptic seizures and syndromes. Epilepsy Res 70(Suppl 1):S27-S33
22. Cunningham BA, Hemperly JJ, Murray BA et al (1987) Neural cell adhesion molecule: structure, immunoglobulin-like domains, cell surface modulation, and alternative RNA splicing. Science 236:799-806 (Pubitemid 17071152)
23. Rønn LC, Hartz BP, Bock E et al (1998) The neural cell adhesion molecule (NCAM) in development and plasticity of the nervous system. Exp Gerontol 33:853-864 (Pubitemid 29019339)
24. Rønn LC, Berezin V, Bock E et al (2000) The neural cell adhesion molecule in synaptic plasticity and ageing. Int J Dev Neurosci 18:193-199 (Pubitemid 30129193)
25. Berezin V, Bock E, Poulsen FM et al (2000) The neural cell adhesion molecule. Curr Opin Drug Discov Dev 3:605-609
26. Bock E, Edvardsen K, Gibson A et al (1987) Characterization of soluble forms of NCAM. FEBS Lett 225:33-36
27. Krog L, Olsen M, Dalseg AM et al (1992) Characterization of soluble neural cell adhesion molecule in rat brain, CSF, and plasma. J Neurochem 59:838-847
28. Fogar P, Basso D, Pasquali C et al (1997) Neural cell adhesion molecule (N-CAM) in gastrointestinal neoplasias. Anticancer Res 17:1227-1230
29. Kameda K, Shimada H, Ishikawa T et al (1999) Expression of highly polysialylated neural cell adhesion molecule in pancreatic cancer neural invasive lesion. Cancer Lett 137:201-207 (Pubitemid 29179464)
30. Sasaki H, Yoshida K, Ikeda E et al (1998) Expression of the neural cell adhesion molecule in astrocytic tumors: an inverse correlation with malignancy. Cancer 82:1921-1931 (Pubitemid 28208649)
31. Tezel E, Kawase Y, Takeda S et al (2001) Expression of neural cell adhesion molecule in pancreatic cancer. Pancreas 22:122-125 (Pubitemid 32179165)
32. Novotny JR, Nückel H, Dührsen U et al (2006) Correlation between expression of CD56/NCAM and severe leukostasis in hyperleukocytic acute myelomonocytic leukaemia. Eur J Haematol 76:299-308 (Pubitemid 43362938)
33. Campodónico PB, de Kier Joffé ED, Urtreger AJ et al (2010) The neural cell adhesion molecule is involved in the metastatic capacity in a murine model of lung cancer. Mol Carcinog 49:386-397
34. Jaques G, Auerbach B, Pritsch M et al (1993) Evaluation of serum neural cell adhesion molecule as a new tumor marker in small cell lung cancer. Cancer 72:418-425 (Pubitemid 23193447)
35. Lehmann JM, Riethmüller G, Johnson JP et al (1989) MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily. Proc Natl Acad Sci USA 86:9891-9895 (Pubitemid 20030740)
36. Shi Y, Liu R, Zhang S et al (2011) Neural cell adhesion molecule potentiates invasion and metastasis of melanoma cells through CAMP-dependent protein kinase and phosphatidylinositol 3-kinase pathways. Int J Biochem Cell Biol 43:682-690
37. Todaro L, Christiansen S, Varela M et al (2007) Alteration of serum and tumoral neural cell adhesion molecule (NCAM) isoforms in patients with brain tumors. J Neurooncol 83:135-144 (Pubitemid 46784986)
38. Zottowska A, Stepński J, Lewko B et al (2001) Neural cell adhesion molecule in breast, colon and lung carcinomas. Arch Immunol Ther Exp (Warsz) 49:171-174
39. Lynch DF Jr, Hassen W, Clements MA et al (1997) Serum levels of endothelial and neural cell adhesion molecules in prostate cancer. Prostate 32:214-220 (Pubitemid 27337956)
40. Fox GB, Kjøller C, Murphy KJ et al (2001) The modulations of NCAM polysialylation state that follow transient global ischemia are brief on neurons but enduring on glia. J Neuropathol Exp Neurol 60:132-140 (Pubitemid 32172416)
41. Rønn LC, Dissing S, Holm A et al (2002) Increased intracellular calcium is required for neurite outgrowth induced by a synthetic peptide ligand of NCAM. FEBS Lett 518:60-66 (Pubitemid 34454964)
42. Gomez TM, Spitzer NC (1999) In vivo regulation of axon extension and pathfinding by growth-cone calcium transients. Nature 397:350-355
43. Sato K, Iwai M, Zhang WR et al (2003) Highly polysialylated neural cell adhesion molecule (PSA-NCAM) positive cells are increased and change localization in rat hippocampus by exposure to repeated kindled seizures. Acta Neurochir Suppl 86:575-579
44. Duveau V, Fritschy JM (2010) PSA-NCAM-dependent GDNF signaling limits neurodegeneration and epileptogenesis in temporal lobe epilepsy. Eur J Neurosci 32:89-98
45. Kiryushko D, Kofoed T, Skladchikova G et al (2003) A synthetic peptide ligand of neural cell adhesion molecule (NCAM), C3d, promotes neuritogenesis and synaptogenesis and modulates pre-synaptic function in primary cultures of rat hippocampal neurons. J Biol Chem 278:12325-12334 (Pubitemid 36800216)
46. Rigau V, Morin M, Rousset MC et al (2007) Angiogenesis is associated with blood-brain barrier permeability in temporal lobe epilepsy. Brain 130:1942-1956 (Pubitemid 47343810)
47. Oby E, Janigro D (2006) The blood-brain barrier and epilepsy. Epilepsia 47:1761-1774 (Pubitemid 44730046)