Effects of DL-3-n-Butylphthalide on vascular dementia and angiogenesis

Neurochemical Research

Volumn 37, Issue 5, 2012, Pages 911-919

  Zhang, Lihong ^a,b   Lü, Lanhai ^c   Chan, W M ^a   Huang, Yin ^d   Wai, Maria S M ^a   Yew, David T ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b HEBEI MEDICAL UNIVERSITY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

^d Central Institute of Pharmaceutical Research   (China)

Author keywords

Angiogenesis; Culture; DL 3 n Butylphthalide (NBP); Morris water maze; Rats; Vascular dementia

Indexed keywords

3 BUTYLPHTHALIDE; FIBROBLAST GROWTH FACTOR 2; HYDROGEN PEROXIDE; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CELL ASSAY; CELL CULTURE; CELL SURVIVAL; CHORIOALLANTOIS; COMMON CAROTID ARTERY; CONTROLLED STUDY; DRUG MECHANISM; IN VITRO STUDY; IN VIVO STUDY; LEARNING; MALE; MAZE TEST; MEMORY CONSOLIDATION; MULTIINFARCT DEMENTIA; NERVE TRANSECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPATIAL LEARNING; TASK PERFORMANCE;

ANIMALS; BENZOFURANS; CELL LINE, TUMOR; CHICK EMBRYO; DEMENTIA, VASCULAR; DRUGS, CHINESE HERBAL; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MAZE LEARNING; NEOVASCULARIZATION, PHYSIOLOGIC; NEUROPROTECTIVE AGENTS; RATS; RATS, INBRED SHR; RATS, INBRED WKY;

ANIMALIA; APIUM GRAVEOLENS VAR. DULCE; RATTUS;

EID: 84862890396     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-011-0663-3     Document Type: Article

References (34)

1. Gironi M, Bianchi A, Russo A, Alberoni M, Ceresa L, Angelini A, Cursano C, Mariani E, Nemni R, Kullmann C, Farina E, Martinelli Boneschi F (2011) Oxidative imbalance in different neurodegenerative diseases with memory impairment. Neurodegener Dis 8:129-137
2. Gorelick PB, Scuteri A, Black SE, Decarli C, Greenberg SM, Iadecola C, Launer LJ, Laurent S, Lopez OL, Nyenhuis D, Petersen RC, Schneider JA, Tzourio C, Arnett DK, Bennett DA, Chui HC, Higashida RT, Lindquist R, Nilsson PM, Roman GC, Sellke FW, Seshadri S; American Heart Association Stroke Council, Council on Epidemiology and Prevention, Council on Cardiovascular Nursing, Council on Cardiovascular Radiology and Intervention, and Council on Cardiovascular Surgery and Anesthesia (2011) Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke 42:2672-2713
3. Román GC (2008) The epidemiology of vascular dementia. Handb Clin Neurol 89:639-658
4. Harrison DG, Gongora MC (2009) Oxidative stress and hypertension. Med Clin North Am 93:621-635
5. Bennetta S, Grantb MM, Aldreda S (2009) Oxidative stress in vascular dementia and Alzheimer's disease: a common pathology. J Alzheimers Dis 17:245-257
6. Zini I, Tomasi A, Grimaldi R, Vannini V, Agnati LF (1992) Detection of free radicals during brain ischemia and reperfusion by spin trapping and microdialysis. Neurosci Lett 138:279-282
7. Li L, Zhang B, Tao Y, Wang Y, Wei H, Zhao J, Huang R, Pei Z (2009) DL-3-n-butylphthalide protects endothelial cells against oxidative/nitrosative stress, mitochondrial damage and subsequent cell death after oxygen glucose deprivation in vitro. Brain Res 1290:91-101
8. Bell RD, Zlokovic BV (2009) Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease. Acta Neuropathol 118:103-113
9. Deng WB, Feng YP (1997) Effect of DL-3-N-Butylphthalide on brain edema in rats subjected to focal cerebral ischemia. Chin Med Sci J 12:102-106
10. Huang JZ, Chen YZ, Su M, Zheng HF, Yang YP, Chen J, Liu CF (2010) Dl-3-n-Butylphthalide prevents oxidative damage and reduces mitochondrial dysfunction in an MPP+-induced cellular model of Parkinson's disease. Neurosci Lett 475:89-94
11. Xiong N, Huang J, Chen C, Zhao Y, Zhang Z, Jia M, Zhang Z, Hou L, Yang H, Cao X, Liang Z, Zhang Y, Sun S, Lin Z, Wang T (2011) Dl-3-n-butylphthalide, a natural antioxidant, protects dopamine neurons in rotenone models for Parkinson's disease. Neurobiol Aging. doi:10.1016/j.neurobiolaging.2011.03.007
12. Li J, Li Y, Ogle M, Zhou X, Song M, Yu SP, Wei L (2010) DL-3-n-butylphthalide prevents neuronal cell death after focal cerebral ischemia in mice via the JNK pathway. Brain Res 1359:216-226
13. Peng Y, Xu SF, Chen G, Wang L, Feng Y, Wang X (2007) I-3-n-Butylphthalide improves cognitive impairment induced by chronic cerebral hypoperfusion in rats. J Pharmacol Exp Ther 321:902-910 (Pubitemid 46762705)
14. Zhang T, Jia WP, Sun XJ (2010) 3-n-Butylphthalide (NBP) reduces apoptosis and enhances vascular endothelial growth factor (VEGF) up-regulation in diabetic rats. Neurol Res 32:1-7
15. Chong Z, Feng Y (1998) Protective effects of dl-3-n-butylphthalide on changes of regional cerebral blood flow and blood-brain barrier damage following experimental subarachnoid hemorrhage. Chin Med J (Engl) 111:858-860 (Pubitemid 28425596)
16. Li QF, Kong SY, Deji QZ, He L, Zhou D (2008) Effects of dl-3-n-butylphthalide on expression of VEGF and bFGF in rat brain with permanent focal cerebral ischemia. Sichuan Da Xue Xue Bao Yi Xue Ban 39:84-88
17. Bromley-Brits K, Deng Y, Song WH (2011) Morris water maze test for learning and memory deficits in Alzheimer's disease model mice. J Vis Exp 53:2920
18. Kirchner LM, Schmidt SP, Gruber BS (1996) Quantitation of angiogenesis in the chick chorioallantoic membrane model using fractal analysis. Microvasc Res 51:2-14 (Pubitemid 26061912)
19. Watanabe H, Ni JW, Sakai Y, Matsumoto K, Murakami Y, Tohda M (1996) Permanent occlusion of bilateral internal carotid arteries produces cognitive deficits in two learning behavior tasks. Nihon Shinkei Seishin Yakurigaku Zasshi 16:19-24 (Pubitemid 26119208)
20. Murakami Y, Tanaka E, Sakai Y, Matsumoto K, Li HB, Watanabe H (1997) Tacrine improves working memory deficit caused by permanent occlusion of bilateral common carotid arteries in rats. Jpn J Pharmacol 75:443-446 (Pubitemid 28020079)
21. Morris R (1984) Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci Methods 11(1): 47-60 (Pubitemid 14088970)
22. Zeng G, Tang T, Wu HJ, You WH, Luo JK, Lin Y, Liang QH, Li XQ, Huang X, Yang QD (2010) Salvianolic acid B protects SHSY5Y neuroblastoma cells from 1-methyl-4-phenylpyridiniuminduced apoptosis. Biol Pharm Bull 33:1337-1342
23. Majesky MW (1996) A little VEGF goes a long way. Therapeutic angiogenesis by direct injection of vascular endothelial growth factor-encoding plasmid DNA. Circulation 94:3062-3064 (Pubitemid 26427464)
24. Hopkins SP, Bulgrin JP, Sims RL, Bowman B, Donovan DL, Schmidt SP (1998) Controlled delivery of vascular endothelial growth factor promotes neovascularization and maintains limb function in a rabbit model of ischemia. J Vasc Surg 27:886-894
25. Wei P, Yu FQ, Chen XL, Tao SX, Han CS, Liu YX (2004) VEGF, bFGF and their receptors at the fetal-maternal interface of the rhesus monkey. Placenta 25:184-196 (Pubitemid 38258174)
26. Przybylski M (2009) A review of the current research on the role of bFGF and VEGF in angiogenesis. J Wound Care 18:516-519
27. Webber MJ, Tongers J, Newcomb CJ, Marquardt KT, Bauersachs J, Losordo DW, Stupp SI (2011) Supramolecular nanostructures that mimic VEGF as a strategy for ischemic tissue repair. Proc Natl Acad Sci USA 108:13438-13443
28. Zhang T, Yan W, Li Q, Fu J, Liu K, Jia W, Sun X, Liu X (2011) 3-n-butylphthalide (NBP) attenuated neuronal autophagy and amyloid-beta expression in diabetic mice subjected to brain ischemia. Neurol Res 33:396-404
29. Wei T, Ni Y, Hou J, Chen C, Zhao B, Xin W (2000) Hydrogen peroxide-induced oxidative damage and apoptosis in cerebellar granule cells: protection by Ginkgo biloba extract. Pharmacol Res 41:427-433
30. Xin W, Wei T, Chen C, Ni Y, Zhao B, Hou J (2000) Mechanisms of apoptosis in rat cerebellar granule cells induced by hydroxyl radicals and the effects of EGb761 and its constituents. Toxicology 148:103-110 (Pubitemid 30621349)
31. Shi C, Yao Z, Xu J, Yew DT (2009) Effects of Ginko Extract (EGb761) on oxidative damage under different conditions of serum supply. J Bioenerg Biomembr 41:61-69
32. Shi C, Zhao L, Zhu B, Li Q, Yew DT, Yao Z, Xu J (2009) Dosage effects of EGb761 on hydrogen peroxide-induced cell death in SH-SY5Y cells. Chem Biol Interact 180:389-397
33. Shi C, Wu F, Yew DT, Xu J, Zhu Y (2010) Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SHSY5Y cells. Apoptosis 15:715-727
34. Lestage P, Lockhart B, Roger A (2002) In vivo exploration of cerebral ischemia: use of neuroprotective agents in animal studies. Terapie 57:554-563