Neuronal hypoxia induces Hsp40-mediated nuclear import of type 3 deiodinase as an adaptive mechanism to reduce cellular metabolism

Journal of Neuroscience

Volumn 32, Issue 25, 2012, Pages 8491-8500

  Jo, Sungro ^a   Kalló, Imre ^b,c   Bardóczi, Zsuzsanna ^b   e Drigo, Rafael Arrojo ^a   Zeöld, Anikó ^b   Liposits, Zsolt ^b,c   Oliva, Anthony ^b   Lemmon, Vance P ^a   Bixby, John L ^a   Gereben, Balázs ^b   Bianco, Antonio C ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^c PÁZMÁNY PÉTER CATHOLIC UNIVERSITY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOTAXIN; ENZYME; HEAT SHOCK PROTEIN 40; THYROID HORMONE RECEPTOR; TYPE 3 DEIODINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CELL HYPOXIA; CELL NUCLEUS; CONTROLLED STUDY; DENTATE HILUS; ELECTRON MICROSCOPY; ENDOPLASMIC RETICULUM; ENZYME GLYCOSYLATION; GENETIC TRANSCRIPTION; GLYCOLYSIS; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MALE; NERVE CELL; NONHUMAN; NUCLEAR IMPORT; PRIORITY JOURNAL; PYRAMIDAL TRACT; RAT; REAL TIME POLYMERASE CHAIN REACTION; THYROID HORMONE METABOLISM;

ANIMALS; BRAIN ISCHEMIA; CELL HYPOXIA; CELL NUCLEUS; CELLS, CULTURED; DNA; ENDOPLASMIC RETICULUM; GLYCOSYLATION; HIPPOCAMPUS; HSP40 HEAT-SHOCK PROTEINS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IODIDE PEROXIDASE; MALE; MICROSCOPY, ELECTRON; MIDDLE CEREBRAL ARTERY; NEURONS; OXYGEN CONSUMPTION; POLYMERASE CHAIN REACTION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, THYROID HORMONE; SIGNAL TRANSDUCTION; THYROID HORMONES;

EID: 84862888248     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.6514-11.2012     Document Type: Article

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