Effects of the combination of metyrapone and oxazepam on cocaine craving and cocaine taking: A double-blind, randomized, placebo-controlled pilot study

Journal of Psychopharmacology

Volumn 26, Issue 7, 2012, Pages 973-981

  Kablinger, Anita S ^a   Lindner, Marie A ^b   Casso, Stephanie ^c   Hefti, Franz ^d   Demuth, George ^e   Fox, Barbara S ^d   McNair, Lindsay A ^f   McCarthy, Bruce G ^g   Goeders, Nicholas E ^d,h  

^a VIRGINIA TECH CARILION SCHOOL OF MEDICINE   (United States)

^b BioAdvance   (United States)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d Embera NeuroTherapeutics Inc   (United States)

^e Stat Tech Services   (United States)

^f Equipoise Consulting LLC   (United States)

^g MERCK RESEARCH LABORATORIES   (United States)

^h LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Benzodiazepine; cocaine; cortisol; craving; HPA axis; metyrapone; oxazepam; stress

Indexed keywords

BENZOYLECGONINE; METYRAPONE; OXAZEPAM; PLACEBO;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COCAINE DEPENDENCE; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; DIARRHEA; DIZZINESS; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG INDUCED HEADACHE; DRUG MEGADOSE; DRUG SAFETY; DRUG TOLERABILITY; DRUG USE; DRUG WITHDRAWAL; EPISTAXIS; FATIGUE; FEMALE; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYPESTHESIA; INCREASED APPETITE; INSOMNIA; IRRITABILITY; LOW DRUG DOSE; MALE; NAUSEA; PILOT STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; SINUSITIS; SOMNOLENCE; THORAX PAIN; TOOTH PAIN; TREATMENT OUTCOME; UPPER ABDOMINAL PAIN; URINARY TRACT INFECTION; VOMITING; WITHDRAWAL SYNDROME; XEROSTOMIA;

ADULT; COCAINE; COCAINE-RELATED DISORDERS; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; ENZYME INHIBITORS; FEMALE; GABA AGONISTS; HUMANS; LOUISIANA; MALE; METYRAPONE; MIDDLE AGED; OXAZEPAM; PATIENT COMPLIANCE; PATIENT DROPOUTS; PILOT PROJECTS; RECURRENCE; STEROID 11-BETA-HYDROXYLASE; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 84862878936     PISSN: 02698811     EISSN: 14617285     Source Type: Journal    
DOI: 10.1177/0269881111430745     Document Type: Article

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