Nanostructured titanium: The ideal material for improving orthopedic implant efficacy?

Nanomedicine

Volumn 7, Issue 6, 2012, Pages 791-793

  Durmus, Naside Gozde ^a   Webster, Thomas J ^a,b  

^a Brown University   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

antibacterial; nanotopography; orthopedic implants; osteoblast function; titanium

Indexed keywords

GENTAMICIN; NANOMATERIAL; TITANIUM;

BACTERIAL CELL; HUMAN; NANOFABRICATION; NANOTECHNOLOGY; NANOTOPOGRAPHY; NONHUMAN; ORTHOPEDIC PROSTHESIS; OSTEOBLAST; PRIORITY JOURNAL; REVIEW;

BONE DEVELOPMENT; HUMANS; NANOSTRUCTURES; NANOTECHNOLOGY; ORTHOPEDICS; OSTEOBLASTS; PROSTHESES AND IMPLANTS; SURFACE PROPERTIES; TITANIUM;

EID: 84862876636     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.12.53     Document Type: Review

References (19)

1. Webster TJ, Siegel RW, Bizios R. Osteoblast adhesion on nanophase ceramics. Biomaterials 20(13), 1221-1227 (1999).
2. Smith R. Bone Health and Osteoporosis: A Report of the Surgeon General. US Department of Health and Human Services, Public Health Service, Office of the Surgeon General. Rockville, MD, USA, 68-70 (2004).
3. Tran N, Webster TJ. Nanotechnology for bone materials. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 1(3), 336-351 (2009).
4. Lentino JR. Prosthetic joint infections: bane of orthopedists, challenge for infectious disease specialists. Clin. Infect. Dis. 36(9), 1157-1161 (2003).
5. Balasundaram G, Webster TJ. A perspective on nanophase materials for orthopedic implant applications. J. Mater. Chem. 16(38), 3737-3745 (2006).
6. Variola F, Vetrone F, Richert L et al. Improving biocompatibitity of implantable metals by nanoscale modification of surfaces: an overview of strategies, fabrication methods, and challenges. Small 5(9), 996-1006 (2009).
7. Nanci A, Wuest JD, Peru L et al. Chemical modification of titanium surfaces for covalent attachment of biological molecules. J. Biomed. Mater. Res. 40(2), 324-335 (1998).
8. Raimondo T, Puckett S, Webster TJ. Greater osteoblast and endothelial cell adhesion on nanostructured polyethylene and titanium. Int. J. Nanomedicine 5, 647-652 (2010).
9. Webster TJ, Ejiofor JU. Increased osteoblast adhesion on nanophase metals: Ti, Ti6Al4V and CoCrMo. Biomaterials 25(19), 4731-4739 (2004).
10. Yao C, Perla V, Mckenzie J, Slamovich EB, Webster TJ. Anodized Ti and Ti6Al4V possessing nanometer surface features enhances osteoblast adhesion. J. Biomed. Nano. 1(1), 68-73 (2005).
11. Ercan B, Webster TJ. The effect of biphasic electrical stimulation on osteoblast function at anodized nanotubular titanium surfaces. Biomaterials 31(13), 3684-3693 (2010).
12. Oh S, Brammer KS, Li YSJ et al. Stem cell fate dictated solely by altered nanotube dimension. Proc. Natl Acad. Sci. USA 106(7), 2130-2135 (2009).
13. Rajyalakshmi A, Ercan B, Balasubramanian K, Webster TJ. Reduced adhesion of macrophages on anodized titanium with select nanotube surface features. Int. J. Nanomedicine 6, 1765-1771 (2011).
14. Bjursten LM, Rasmusson L, Oh S, Smith GC, Brammer KS, Jin S. Titanium dioxide nanotubes enhance bone bonding in vivo. J. Biomed. Mater. Res. Part A 92A(3), 1218-1224 (2010).
15. Puckett SD. Select Nanofabricated Titanium Materials for Enhancing Bone and Skin Growth of Intraosseous Transcutaneous Amputation Prostheses. Brown University, RI, USA (2010).
16. Puckett SD, Taylor E, Raimondo T, Webster TJ. The relationship between the nanostructure of titanium surfaces and bacterial attachment. Biomaterials 31(4), 706-713 (2010).
17. Ercan B, Kummer KM, Tarquinio KM, Webster TJ. Decreased Staphylococcus aureus biofilm growth on anodized nanotubular titanium and the effect of electrical stimulation. Acta Biomaterialia 7(7), 3003-3012 (2011).
18. Popat KC, Eltgroth M, Latempa TJ, Grimes CA, Desai TA. Decreased Staphylococcus epidermis adhesion and increased osteoblast functionality on antibiotic-loaded titania nanotubes. Biomaterials 28(32), 4880-4888 (2007).
19. Zhao LZ, Wang HR, Huo KF et al. Antibacterial nano-structured titania coating incorporated with silver nanoparticles. Biomaterials 32(24), 5706-5716 (2011).