New topoisomerases inhibitors: Synthesis of rutaecarpine derivatives and their inhibitory activity against topoisomerases

Archives of Pharmacal Research

Volumn 35, Issue 5, 2012, Pages 785-789

  Kim, Seung Ill ^a   Lee, Seung Ho ^a   Lee, Eung Seok ^a   Lee, Chong Soon ^a   Jahng, Yurngdong ^a  

^a Yeungnam University   (South Korea)

Author keywords

Indoloquinazoline alkaloid; Rutaecarpine; Topoisomerase I; Topoisomerase II

Indexed keywords

10 BROMORUTAECARPINE; 3 CHLORORUTAECARPINE; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE INHIBITOR; RUTAECARPINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG STRUCTURE; ENZYME INHIBITION; SYNTHESIS;

CELL LINE, TUMOR; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; HUMANS; INDOLE ALKALOIDS; QUINAZOLINES; RUTACEAE; TOPOISOMERASE I INHIBITORS; TOPOISOMERASE II INHIBITORS;

EID: 84862870086     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-012-0504-1     Document Type: Article

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