Safety of coronary reactivity testing in women with no obstructive coronary artery disease: Results from the NHLBI-sponsored WISE (Women's Ischemia Syndrome Evaluation) study

JACC: Cardiovascular Interventions

Volumn 5, Issue 6, 2012, Pages 646-653

  Wei, Janet ^a   Mehta, Puja K ^a   Johnson, B Delia ^b   Samuels, Bruce ^a   Kar, Saibal ^a   Anderson, R David ^c   Azarbal, Babak ^a   Petersen, John ^c   Sharaf, Barry ^d   Handberg, Eileen ^c   Shufelt, Chrisandra ^a   Kothawade, Kamlesh ^a   Sopko, George ^e   Lerman, Amir ^f   Shaw, Leslee ^g   Kelsey, Sheryl F ^b   Pepine, Carl J ^c   Merz, C Noel Bairey ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF FLORIDA   (United States)

^d BROWN UNIVERSITY   (United States)

^e NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^f MAYO CLINIC   (United States)

^g EMORY UNIVERSITY   (United States)

Author keywords

coronary reactivity; endothelial dysfunction; microvascular dysfunction

Indexed keywords

ACETYLCHOLINE; ADENOSINE; GLYCERYL TRINITRATE;

ADULT; AIR EMBOLISM; ARTICLE; BLOOD VESSEL REACTIVITY; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORONARY ARTERY DISSECTION; CORONARY ARTERY SPASM; DEEP VEIN THROMBOSIS; DISEASE COURSE; FEMALE; FOLLOW UP; HEART ARRHYTHMIA; HEART FAILURE; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HOSPITALIZATION; HUMAN; HYPOTENSION; LEFT CORONARY ARTERY; MAJOR CLINICAL STUDY; MICROANGIOPATHY; MICROEMBOLISM; PRIORITY JOURNAL; STROKE;

ACETYLCHOLINE; ADENOSINE; ADULT; BLOOD FLOW VELOCITY; CORONARY ANGIOGRAPHY; CORONARY CIRCULATION; CORONARY VESSELS; FEMALE; HEART FAILURE; HOSPITALIZATION; HUMANS; LASER-DOPPLER FLOWMETRY; MICROCIRCULATION; MIDDLE AGED; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; NITROGLYCERIN; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RISK ASSESSMENT; RISK FACTORS; STROKE; UNITED STATES; VASODILATOR AGENTS;

EID: 84862863305     PISSN: 19368798     EISSN: 18767605     Source Type: Journal    
DOI: 10.1016/j.jcin.2012.01.023     Document Type: Article

References (41)

1. Jespersen L, Hvelplund A, Abildstrom SZ, et al. Stable angina pectoris with no obstructive coronary artery disease is associated with increased risks of major adverse cardiovascular events. Eur Heart J 2012;33:734-44.
2. Anderson RD, Pepine CJ. Gender differences in the treatment for acute myocardial infarction: bias or biology? Circulation 2007;115:823-6. (Pubitemid 46294721)
3. Reis SE, Holubkov R, Conrad Smith AJ, et al. Coronary microvascular dysfunction is highly prevalent in women with chest pain in the absence of coronary artery disease: results from the NHLBI WISE study. Am Heart J 2001;141:735-41. (Pubitemid 32378481)
4. Shaw LJ, Bugiardini R, Merz CN. Women and ischemic heart disease: evolving knowledge. J Am Coll Cardiol 2009;54:1561-75.
5. Reynolds HR, Srichai MB, Iqbal SN, et al. Mechanisms of myocardial infarction in women without angiographically obstructive coronary artery disease. Circulation 2011;124:1414-25.
6. Carpiuc KT, Wingard DL, Kritz-Silverstein D, Barrett-Connor E. The association of angina pectoris with heart disease mortality among men and women by diabetes status: the Rancho Bernardo study. J Womens Health (Larchmt) 2010;19:1433-9.
7. Hemingway H, Langenberg C, Damant J, Frost C, Pyörälä K, Barrett-Connor E. Prevalence of angina in women versus men: a systematic review and meta-analysis of international variations across 31 countries. Circulation 2008;117:1526-36. (Pubitemid 351440641)
8. Johnson BD, Shaw LJ, Pepine CJ, et al. Persistent chest pain predicts cardiovascular events in women without obstructive coronary artery disease: results from the NIH-NHLBI-sponsored Women's Ischaemia Syndrome Evaluation (WISE) study. Eur Heart J 2006;27:1408-15.
9. von Mering GO, Arant CB, Wessel TR, et al. Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute- Sponsored Women's Ischemia Syndrome Evaluation (WISE). Circulation 2004;109:722-5. (Pubitemid 38222890)
10. Gulati M, Cooper-DeHoff RM, McClure C, et al. Adverse cardiovascular outcomes in women with nonobstructive coronary artery disease: a report from the Women's Ischemia Syndrome Evaluation Study and the St James Women Take Heart Project. Arch Intern Med 2009;169: 843-50.
11. Lanza GA, Buffon A, Sestito A, et al. Relation between stress-induced myocardial perfusion defects on cardiovascular magnetic resonance and coronary microvascular dysfunction in patients with cardiac syndrome X. J Am Coll Cardiol 2008;51:466-72.
12. Halcox JP, Schenke WH, Zalos G, et al. Prognostic value of coronary vascular endothelial dysfunction. Circulation 2002;106:653-8. (Pubitemid 34851922)
13. Schächinger V, Britten MB, Zeiher AM. Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation 2000;101:1899-906. (Pubitemid 30225269)
14. Suwaidi JA, Hamasaki S, Higano ST, Nishimura RA, Holmes DR Jr., Lerman A. Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction. Circulation 2000;101:948-54. (Pubitemid 30131694)
15. Ong P, Athanasiadis A, Hill S, Vogelsberg H, Voehringer M, Sechtem U. Coronary artery spasm as a frequent cause of acute coronary syndrome: the CASPAR (Coronary Artery Spasm in Patients With Acute Coronary Syndrome) study. J Am Coll Cardiol 2008;52:523-7.
16. Wakabayashi K, Suzuki H, Honda Y, et al. Provoked coronary spasm predicts adverse outcome in patients with acute myocardial infarction: a novel predictor of prognosis after acute myocardial infarction. J Am Coll Cardiol 2008;52:518-22.
17. Sovari AA, Cesario D, Kocheril AG, Brugada R. Multiple episodes of ventricular tachycardia induced by silent coronary vasospasm. J Interv Card Electrophysiol 2008;21:223-6.
18. MacAlpin RN. Cardiac arrest and sudden unexpected death in variant angina: complications of coronary spasm that can occur in the absence of severe organic coronary stenosis. Am Heart J 1993;125:1011-7. (Pubitemid 23117332)
19. Pepine CJ, Anderson RD, Sharaf BL, et al. Coronary microvascular reactivity to adenosine predicts adverse outcome in women evaluated for suspected ischemia results from the National Heart, Lung and Blood Institute WISE (Women's Ischemia Syndrome Evaluation) study. J Am Coll Cardiol 2010;55:2825-32.
20. Bonetti PO, Barsness GW, Keelan PC, et al. Enhanced external counterpulsation improves endothelial function in patients with symptomatic coronary artery disease. J Am Coll Cardiol 2003;41:1761-8. (Pubitemid 36584250)
21. Modena MG, Bonetti L, Coppi F, Bursi F, Rossi R. Prognostic role of reversible endothelial dysfunction in hypertensive postmenopausal women. J Am Coll Cardiol 2002;40:505-10. (Pubitemid 34833167)
22. Yasue H, Mizuno Y, Harada E, et al. Effects of a 3-hydroxy-3- methylglutaryl coenzyme A reductase inhibitor, fluvastatin, on coronary spasm after withdrawal of calcium-channel blockers. J Am Coll Cardiol 2008;51:1742-8. (Pubitemid 351608498)
23. Pauly DF, Johnson BD, Anderson RD, et al. In women with symptoms of cardiac ischemia, nonobstructive coronary arteries, and microvascular dysfunction, angiotensin-converting enzyme inhibition is associated with improved microvascular function: a double-blind randomized study from the National Heart, Lung and Blood Institute Women's Ischemia Syndrome Evaluation (WISE). Am Heart J 2011;162:678-84.
24. Lerman A, Zeiher AM. Endothelial function: cardiac events. Circulation 2005;111:363-8. (Pubitemid 40165345)
25. Bairey Merz CN, Shaw LJ, Reis SE, et al. Insights from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) study: part II: gender differences in presentation, diagnosis, and outcome with regard to gender-based pathophysiology of atherosclerosis and macrovascular and microvascular coronary disease. J Am Coll Cardiol 2006;47:S21-9.
26. Scanlon PJ, Faxon DP, Audet AM, et al. ACC/AHA guidelines for coronary angiography: a report of the American College of Cardiology/ American Heart Association Task Force on Practice Guidelines, (Committee on Coronary Angiography). J Am Coll Cardiol 1999; 33:1756-824.
27. Kennedy JW. Complications associated with cardiac catheterization and angiography. Cathet Cardiovasc Diagn 1982;8:5-11. (Pubitemid 12106612)
28. Mehta PK, Goykhman P, Thomson LE, et al. Ranolazine improves angina in women with evidence of myocardial ischemia but no obstructive coronary artery disease. J Am Coll Cardiol Img 2011;4: 514-22.
29. Bugiardini R, Bairey Merz CN. Angina with "normal" coronary arteries: a changing philosophy. JAMA 2005;293:477-84.
30. Abebe W, Makujina SR, Mustafa SJ. Adenosine receptor-mediated relaxation of porcine coronary artery in presence and absence of endothelium. Am J Physiol 1994;266:H2018-25.
31. Scanlon PJ, Faxon DP, Audet AM, et al. ACC/AHA guidelines for coronary angiography: executive summary and recommendations. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Coronary Angiography). Circulation 1999;99:2345-57.
32. Doucette JW, Corl PD, Payne HM, et al. Validation of a Doppler guide wire for intravascular measurement of coronary artery flow velocity. Circulation 1992;85:1899-911.
33. Bach RG, Kern MJ. Practical coronary physiology. Clinical application of the Doppler flow velocity guide wire. Cardiol Clin 1997;15:77-99. (Pubitemid 27106419)
34. Qian J, Ge J, Baumgart D, et al. Safety of intracoronary Doppler flow measurement. Am Heart J 2000;140:502-10.
35. Mechem C, Kern MJ, Aguirre F, Cauley M, Stonner T. Safety and outcome of angioplasty guidewire Doppler instrumentation in patients with normal or mildly diseased coronary arteries (abstr). Circulation 1992; 86:I323.
36. Rieber J, Jung P, Schiele TM, et al. Safety of FFR-based treatment strategies: the Munich experience. Z Kardiol 2002;91 Suppl 3:115-9. (Pubitemid 34811954)
37. Jeremias A, Whitbourn RJ, Filardo SD, et al. Adequacy of intracoronary versus intravenous adenosine-induced maximal coronary hyperemia for fractional flow reserve measurements. Am Heart J 2000; 140:651-7.
38. De Bruyne B, Pijls NH, Barbato E, et al. Intracoronary and intravenous adenosine 5′-triphosphate, adenosine, papaverine, and contrast medium to assess fractional flow reserve in humans. Circulation 2003;107:1877-83. (Pubitemid 36444128)
39. Wilson RF, Wyche K, Christensen BV, Zimmer S, Laxson DD. Effects of adenosine on human coronary arterial circulation. Circulation 1990;82:1595-606. (Pubitemid 20367962)
40. Sueda S, Oshita A, Nomoto T, et al. Recommendations for performing acetylcholine tests safely: STOP Dangerous Complications Induced by Acetylcholine Tests (STOP DCIAT). J Cardiol 2008;51:131-4. (Pubitemid 351690468)
41. Lüscher TF, Pieper M, Tendera M, et al. A randomized placebocontrolled study on the effect of nifedipine on coronary endothelial function and plaque formation in patients with coronary artery disease: the ENCORE II study. Eur Heart J 2009;30:1590-7.