Assembly of aptamer switch probes and photosensitizer on gold nanorods for targeted photothermal and photodynamic cancer therapy

ACS Nano

Volumn 6, Issue 6, 2012, Pages 5070-5077

  Wang, Jian ^a,b   Zhu, Guizhi ^a,c   You, Mingxu ^a   Song, Erqun ^a,b   Shukoor, Mohammed Ibrahim ^a   Zhang, Kejing ^a   Altman, Meghan B ^a   Chen, Yan ^a,c   Zhu, Zhi ^a,c   Huang, Cheng Zhi ^b   Tan, Weihong ^a,c  

^a University of Florida ^*  (United States)

^b SOUTHWEST UNIVERSITY   (China)

^c HUNAN UNIVERSITY   (China)

Author keywords

aptamer switch probe; cancer therapy; gold nanorods; photosensitizer

Indexed keywords

APTAMERS; CANCER CELLS; CANCER THERAPY; CELL DESTRUCTION; CHLORIN E6; GOLD NANOROD; GOLD SURFACES; HIGH SPECIFICITY; LIGHT IRRADIATIONS; MULTI-MODAL; PHOTO-THERMAL; PHOTOSENSITIZER MOLECULE; PHOTOTHERMAL EFFECTS; PHOTOTHERMAL THERAPY; SINGLET OXYGEN; THERAPEUTIC EFFECTS; THERAPEUTIC EFFICIENCY;

CELLS; MOLECULES; NANORODS; ONCOLOGY; PHOTODYNAMIC THERAPY; PLASMONS; PROBES;

PHOTOSENSITIZERS;

CHLORIN E6; GOLD; NANOTUBE; PEPTIDE APTAMER; PHOTOSENSITIZING AGENT; PORPHYRIN;

ANIMAL; ARTICLE; CHEMISTRY; DRUG DELIVERY SYSTEM; EXPERIMENTAL NEOPLASM; HYPERTHERMIC THERAPY; METHODOLOGY; MOUSE; PATHOLOGY; PHOTOCHEMOTHERAPY; TREATMENT OUTCOME; TUMOR CELL LINE;

ANIMALS; APTAMERS, PEPTIDE; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; GOLD; HYPERTHERMIA, INDUCED; MICE; NANOTUBES; NEOPLASMS, EXPERIMENTAL; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PORPHYRINS; TREATMENT OUTCOME;

EID: 84862840610     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn300694v     Document Type: Article

References (37)

1. Kuo, W.-S.; Chang, C.-N.; Chang, Y.-T.; Yang, M.-H.; Chien, Y.-H.; Chen, S.-J.; Yeh, C.-S. Gold Nanorods in Photodynamic Therapy, as Hyperthermia Agents, and in Near-Infrared Optical Imaging Angew. Chem., Int. Ed. 2010, 49, 2711-2715
2. Kah, J. C. Y.; Wan, R. C. Y.; Wong, K. Y.; Mhaisalkar, S.; Sheppard, C. J. R.; Olivo, M. Combinatorial Treatment of Photothermal Therapy Using Gold Nanoshells with Conventional Photodynamic Therapy to Improve Treatment Efficacy: An In Vitro Study Laser Surg. Med. 2008, 40, 584-589
3. Jang, B.; Park, J.-Y.; Tung, C.-H.; Kim, I.-H.; Choi, Y. Gold Nanorod-Photosensitizer Complex for Near-Infrared Fluorescence Imaging and Photodynamic/Photothermal Therapy in Vivo ACS Nano 2011, 5, 1086-1094
4. Barth, B. M.; Altnoǧlu, E. I.; Shanmugavelandy, S. S.; Kaiser, J. M.; Crespo-Gonzalez, D.; DiVittore, N. A.; McGovern, C.; Goff, T. M.; Keasey, N. R.; Adair, J. H. et al. Targeted Indocyanine-Green-Loaded Calcium Phosphosilicate Nanoparticles for in Vivo Photodynamic Therapy of Leukemia ACS Nano 2011, 26, 5325-5337
5. Oseroff, A. R.; Ohuoha, D.; Hasan, T.; Bommer, J. C.; Yarmush, M. L. Antibody-Targeted Photolysis: Selective Photodestruction of Human T-Cell Leukemia Cells Using Monoclonal Antibody-Chlorin e6 Conjugates Proc. Natl. Acad. Sci. U. S. A. 1986, 83, 8744-8748
6. Huang, Y.-F.; Sefah, K.; Bamrungsap, S.; Chang, H.-T.; Tan, W. Selective Photothermal Therapy for Mixed Cancer Cells Using Aptamer-Conjugated Nanorods Langmuir 2008, 24, 11860-11865
7. Huang, Y.-F.; Chang, H.-T.; Tan, W. Cancer Cell Targeting Using Multiple Aptamers Conjugated on Nanorods Anal. Chem. 2008, 80, 567-572
8. Koo, H.; Huh, M. S.; Sun, I.-C.; Yuk, S. H.; Choi, K.; Kim, K.; Kwon, I. C. In Vivo Targeted Delivery of Nanoparticles for Theranosis Acc. Chem. Res. 2011, 44, 1018-1028
9. Wang, H.; Yang, R.; Yang, L.; Tan, W. Nucleic Acid Conjugated Nanomaterials for Enhanced Molecular Recognition ACS Nano 2009, 3, 2451-2460
10. Kong, R.-M.; Zhang, X.-B.; Chen, Z.; Tan, W. Aptamer-Assembled Nanomaterials for Biosensing and Biomedical Applications Small 2011, 7, 2428-2436
11. Wang, J.; Zhang, P.; Li, J. Y.; Chen, L. Q.; Huang, C. Z.; Li, Y. F. Adenosine-Aptamer Recognition-Induced Assembly of Gold Nanorods and a Highly Sensitive Plasmon Resonance Coupling Assay of Adenosine in the Brain of Model SD Rat Analyst 2010, 135, 2826-2831
12. Song, S.; Wang, L.; Li, J.; Zhao, J.; Fan, C. Aptamer-Based Biosensors Trends Anal. Chem. 2008, 27, 108-117
13. Zhen, S. J.; Chen, L. Q.; Xiao, S. J.; Li, Y. F.; Hu, P. P.; Zhan, L.; Peng, L.; Song, E. Q.; Huang, C. Z. Carbon Nanotubes as a Low Background Signal Platform for a Molecular Aptamer Beacon on the Basis of Long-Range Resonance Energy Transfer Anal. Chem. 2010, 82, 8432-8437
14. Fang, X.; Tan, W. Aptamers Generated from Cell-SELEX for Molecular Medicine: A Chemical Biology Approach Acc. Chem. Res. 2010, 43, 48-57
15. Tang, Z.; Shangguan, D.; Wang, K.; Shi, H.; Sefah, K.; Mallikratchy, P.; Chen, H. W.; Li, Y.; Tan, W. Selection of Aptamers for Molecular Recognition and Characterization of Cancer Cells Anal. Chem. 2007, 79, 4900-4907
16. Sefah, K.; Tang, Z.; Shangguan, D.; Chen, H.; Lopez-Colon, D.; Li, Y.; Parekh, P.; Martin, J.; Meng, L.; Phillips, J. A. et al. Molecular Recognition of Acute Myeloid Leukemia Using Aptamers Leukemia 2009, 23, 235-244
17. Chen, X.; Huang, Y.; Tan, W. Using Aptamer-Nanoparticle Conjugates for Cancer Cells Detection J. Biomed. Nanotechnol. 2008, 4, 400-409
18. Tan, W.; Wang, H.; Chen, Y.; Zhang, X.; Zhu, H.; Yang, C.; Yang, R.; Liu, C. Molecular Aptamers for Drug Delivery Trends Biotechnol. 2011, 29, 634-640
19. Wang, K.; You, M.; Chen, Y.; Han, D.; Zhu, Z.; Huang, J.; Williams, K.; Yang, C. J.; Tan, W. Self-Assembly of a Bifunctional DNA Carrier for Drug Delivery Angew. Chem., Int. Ed. 2011, 50, 6098-6101
20. Wu, Z.; Tang, L.-J.; Zhang, X.-B.; Jiang, J.-H.; Tan, W. Aptamer-Modified Nanodrug Delivery Systems ACS Nano 2011, 5, 7696-7699
21. Chang, M.; Yang, C.-S.; Huang, D.-M. Aptamer-Conjugated DNA Icosahedral Nanoparticles As a Carrier of Doxorubicin for Cancer Therapy ACS Nano 2011, 5, 6156-6163
22. Kim, D.; Jeong, Y. Y.; Jon, S. A Drug-Loaded Aptamer-Gold Nanoparticle Bioconjugate for Combined CT Imaging and Therapy of Prostate Cancer ACS Nano 2010, 4, 3689-3696
23. Tang, Z.; Zhu, Z.; Mallikaratchy, P.; Yang, R.; Sefah, K.; Tan, W. Aptamer-Target Binding Triggered Molecular Mediation of Singlet Oxygen Generation Chem. Asian J. 2010, 5, 783-786
24. Shieh, Y.-A.; Yang, S.-J.; Wei, M.-F.; Shieh, M.-J. Aptamer-Based Tumor-Targeted Drug Delivery for Photodynamic Therapy ACS Nano 2010, 4, 1433-1442
25. Barth, B. M.; I. Altinoǧlu, E.; Shanmugavelandy, S. S.; Kaiser, J. M.; Crespo-Gonzalez, D.; DiVittore, N. A.; McGovern, C.; Goff, T. M.; Keasey, N. R.; Adair, J. H. et al. Targeted Indocyanine-Green-Loaded Calcium Phosphosilicate Nanoparticles for in Vivo Photodynamic Therapy of Leukemia ACS Nano 2011, 5, 5325-5337
26. Chari, R. V. J. Targeted Cancer Therapy: Conferring Specificity to Cytotoxic Drugs Acc. Chem. Res. 2008, 41, 98-107
27. Chin, W. W. L.; Heng, P. W. S.; Olivo, M. Chlorin e6-Polyvinylpyrrolidone Mediated Photosensitization is Effective Against Human Non-Small Cell Lung Carcinoma Compared to Small Cell Lung Carcinoma Xenografts BMC Pharm. 2007, 7, 15
28. Shi, H.; He, X.; Wang, K.; Wu, X.; Ye, X.; Guo, Q.; Tan, W.; Qing, Z.; Yang, X.; Zhou, B. Activatable Aptamer Probe for Contrast-Enhanced in Vivo Cancer Imaging Based on Cell Membrane Protein-Triggered Conformation Alteration Proc. Natl. Acad. Sci. U. S. A. 2011, 108, 3900-3905
29. Tang, Z.; Mallikaratchy, P.; Yang, R.; Kim, Y.; Zhu, Z.; Wang, H.; Tan, W. Aptamer Switch Probe Based on Intramolecular Displacement J. Am. Chem. Soc. 2008, 130, 11268-11269
30. Alkilany, A. M.; Thompson, L. B.; Boulos, S. P.; Sisco, P. N.; Murphy, C. J. Gold Nanorods: Their Potential for Photothermal Therapeutics and Drug Delivery, Tempered by the Complexity of Their Biological Interactions Adv. Drug Delivery Rev. 2012, 64, 190-199
31. Wang, J.; Li, Y. F.; Huang, C. Z. Identification of Iodine-Induced Morphological Transformation of Gold Nanorods J. Phys. Chem. C 2008, 112, 11691-11695
32. Huang, P.; Li, Z.; Lin, J.; Yang, D.; Gao, G.; Xu, C.; Bao, L.; Zhang, C.; Wang, K.; Song, H. et al. Photosensitizer-Conjugated Magnetic Nanoparticles for in Vivo Vimultaneous Magnetofluorescent Imaging and Targeting Therapy Biomaterials 2011, 32, 3447-3458
33. Shangguan, D.; Li, Y.; Tang, Z.; Cao, Z. C.; Chen, H. W.; Mallikaratchy, P.; Sefah, K.; Yang, C. J.; Tan, W. Aptamers Evolved from Live Cells as Effective Molecular Probes for Cancer Study Proc. Natl. Acad. Sci. U. S. A. 2006, 103, 11838-11843
34. Xiao, Z.; Shangguan, D.; Cao, Z.; Fang, X.; Tan, W. Cell-Specific Internalization Study of an Aptamer from Whole Cell Selection Chem.-Eur. J. 2008, 14, 1769-1775
35. Zhu, Z.; Tang, Z.; Phillips, J. A.; Yang, R.; Wang, H.; Tan, W. Regulation of Singlet Oxygen Generation Using Single-Walled Carbon Nanotubes J. Am. Chem. Soc. 2008, 130, 10856-10857
36. Jang, B.; Kim, Y. S.; Choi, Y. Effects of Gold Nanorod Concentration on the Depth-Related Temperature Increase during Hyperthermic Ablation Small 2010, 7, 265-270
37. Luo, Y.-L.; Shiao, Y.-S.; Huang, Y.-F. Release of Photoactivatable Drugs from Plasmonic Nanoparticles for Targeted Cancer Therapy ACS Nano 2011, 5, 7796-7804