Static autoregulation is intact early after severe unilateral brain injury in a neonatal swine model

Neurosurgery

Volumn 71, Issue 1, 2012, Pages 138-145

  Mytar, Jennifer ^a   Kibler, Kathleen K ^b   Easley, R Blaine ^b   Smielewski, Peter ^c   Czosnyka, Marek ^b   Andropoulos, Dean B ^b   Brady, Ken M ^b  

^a Touro University California   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

Autoregulation; Neurotrauma; Pediatric

Indexed keywords

GLUCOSE; HEMOGLOBIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL GAS; ARTICLE; AUTOREGULATION; BLOOD OXYGEN TENSION; BLOOD PH; BODY TEMPERATURE; BRAIN EDEMA; BRAIN HERNIA; BRAIN PERFUSION; CONTROLLED STUDY; DISEASE SEVERITY; EXPERIMENTAL PIG; FEMALE; GLUCOSE BLOOD LEVEL; HEMISPHERE; HEMOGLOBIN BLOOD LEVEL; HYPOTENSION; INTRACRANIAL PRESSURE; LASER DOPPLER FLOWMETRY; MALE; MEAN ARTERIAL PRESSURE; NEWBORN; NONHUMAN; OXYGEN TENSION; PERFUSION PRESSURE; PH; PRIORITY JOURNAL; SHAM PROCEDURE; TRAUMATIC BRAIN INJURY;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; BLOOD FLOW VELOCITY; BRAIN INJURIES; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; FUNCTIONAL LATERALITY; HOMEOSTASIS; HYPOTENSION; INTRACRANIAL PRESSURE; LASER-DOPPLER FLOWMETRY; SEVERITY OF ILLNESS INDEX; SWINE; TIME FACTORS;

EID: 84862835691     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/NEU.0b013e318251795a     Document Type: Article

References (21)

1. Adelson PD, Bratton SL, Carney NA, et al. Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 8. Cerebral perfusion pressure. Pediatr Crit Care Med. 2003;4(3 suppl): S31-S33.
2. Czosnyka M, Smielewski P, Kirkpatrick P, Laing RJ, Menon D, Pickard JD. Continuous assessment of the cerebral vasomotor reactivity in head injury. Neurosurgery. 1997;41(1):11-17; discussion 17-19.
3. Steiner LA, Czosnyka M, Piechnik SK, et al. Continuous monitoring of cerebrovascular pressure reactivity allows determination of optimal cerebral perfusion pressure in patients with traumatic brain injury. Crit Care Med. 2002;30(4):733-738. (Pubitemid 34297786)
4. Bratton SL, Chestnut RM, Ghajar J, et al. Guidelines for the management of severe traumatic brain injury. IX. Cerebral perfusion thresholds. J Neurotrauma. 2007;24(suppl 1):S59-S64.
5. Czosnyka M, Smielewski P, Kirkpatrick P, Menon DK, Pickard JD. Monitoring of cerebral autoregulation in head-injured patients. Stroke. 1996;27(10):1829-1834. (Pubitemid 26332515)
6. Brady KM, Shaffner DH, Lee JK, et al. Continuous monitoring of cerebrovascular pressure reactivity after traumatic brain injury in children. Pediatrics. 2009;124(6): e1205-e1212.
7. Rangel-Castilla L, Gasco J, Nauta HJ, Okonkwo DO, Robertson CS. Cerebral pressure autoregulation in traumatic brain injury. Neurosurg Focus. 2008; 25(4):E7.
8. Forbes ML, Hendrich KS, Kochanek PM, et al. Assessment of cerebral blood flow and CO2 reactivity after controlled cortical impact by perfusion magnetic resonance imaging using arterial spin-labeling in rats. J Cereb Blood Flow Metab. 1997;17(8):865-874. (Pubitemid 27377641)
9. Armstead WM, Kiessling JW, Kofke WA, Vavilala MS. Impaired cerebral blood flow autoregulation during posttraumatic arterial hypotension after fluid percussion brain injury is prevented by phenylephrine in female but exacerbated in male piglets by extracellular signal-related kinase mitogen-activated protein kinase upregulation. Crit Care Med. 2010;38(9):1868-1874.
10. Brady KM, Lee JK, Kibler KK, et al. Continuous time-domain analysis of cerebrovascular autoregulation using near-infrared spectroscopy. Stroke. 2007;38 (10):2818-2825. (Pubitemid 47494023)
11. Brady KM, Lee JK, Kibler KK, Easley RB, Koehler RC, Shaffner DH. Continuous measurement of autoregulation by spontaneous fluctuations in cerebral perfusion pressure: comparison of 3 methods. Stroke. 2008;39(9):2531-2537.
12. Engelborghs K, Haseldonckx M, Van Reempts J, et al. Impaired autoregulation of cerebral blood flow in an experimental model of traumatic brain injury. J Neurotrauma. 2000;17(8):667-677.
13. Freeman SS, Udomphorn Y, Armstead WM, Fisk DM, Vavilala MS. Young age as a risk factor for impaired cerebral autoregulation after moderate to severe pediatric traumatic brain injury. Anesthesiology. 2008;108(4):588-595. (Pubitemid 351440578)
14. Lang EW, Yip K, Griffith J, Lagopoulos J, Mudaliar Y, Dorsch NW. Hemispheric asymmetry and temporal profiles of cerebral pressure autoregulation in head injury. J Clin Neurosci. 2003;10(6):670-673. (Pubitemid 37408627)
15. Brady KM, Lee JK, Kibler KK, et al. The lower limit of cerebral blood flow autoregulation is increased with elevated intracranial pressure. Anesth Analg. 2009; 108(4):1278-1283.
16. Cremer OL, van Dijk GW, Amelink GJ, de Smet AM, Moons KG, Kalkman CJ. Cerebral hemodynamic responses to blood pressure manipulation in severely head-injured patients in the presence or absence of intracranial hypertension. Anesth Analg. 2004;99(4):1211-1217, table of contents. (Pubitemid 39287420)
17. Chieregato A, Tanfani A, Compagnone C, et al. Global cerebral blood flow and CPP after severe head injury: a xenon-CT study. Intensive Care Med. 2007;33(5): 856-862. (Pubitemid 46675333)
18. Lassen NA. Cerebral blood flow and oxygen consumption in man. Physiol Rev. 1959;39(2):183-238.
19. Chieregato A, Tanfani A, Compagnone C, Pascarella R, Targa L, Fainardi E. Cerebral blood flow in traumatic contusions is predominantly reduced after an induced acute elevation of cerebral perfusion pressure. Neurosurgery. 2007;60(1): 115-123; discussion 123.
20. Schmidt EA, Czosnyka M, Smielewski P, Piechnik SK, Pickard JD. Asymmetry of cerebral autoregulation following head injury. Acta Neurochir Suppl. 2002;81: 133-134.
21. Schmidt EA, Czosnyka M, Steiner LA, et al. Asymmetry of pressure autoregulation after traumatic brain injury. J Neurosurg. 2003;99(6):991-998. (Pubitemid 44717394)