S-Nitrosylation of mitogen activated protein kinase phosphatase-1 suppresses radiation-induced apoptosis

Cancer Letters

Volumn 314, Issue 2, 2012, Pages 137-146

  Guan, Weiping ^a   Sha, Jibin ^b   Chen, Xiaojuan ^c   Xing, Yaling ^c   Yan, Jinqi ^d   Wang, Zhaoqing ^c  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b XI'AN JIAOTONG UNIVERSITY   (China)

^c BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^d BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

Head and neck cancer; MKP 1; Radiotherapy; S nitrosylation

Indexed keywords

CYSTEINE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; DUSP1 PROTEIN, HUMAN; DUSP1 PROTEIN, MOUSE; INDUCIBLE NITRIC OXIDE SYNTHASE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL; CANCER RADIOTHERAPY; CANCER RESISTANCE; COCULTURE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME STABILITY; GENETIC TRANSFECTION; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; HUMAN TISSUE; IRRADIATION; MACROPHAGE ACTIVATION; MOUSE; NITROSYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOSENSITIVITY; TUMOR MICROENVIRONMENT; ANIMAL; CELL LINE; GAMMA RADIATION; GENETICS; METABOLISM; PHYSIOLOGY; RADIATION DOSE; RADIATION EXPOSURE; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; CELL LINE; CELL LINE, TUMOR; DUAL SPECIFICITY PHOSPHATASE 1; GAMMA RAYS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICE; NITRIC OXIDE SYNTHASE TYPE II; RADIATION TOLERANCE;

EID: 84862833072     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2011.09.022     Document Type: Article

References (36)

1. J.S. Stamler, S. Lamas, F.C. Fang, Nitrosylation. The prototypic redoxbased signaling mechanism, Cell 106 (2001) 675-683.
2. J.S. Stamler, O. Jaraki, J. Osborne, D.I. Simon, J. Keaney, J. Vita, D. Singel, C.R. Valeri, J. Loscalzo, Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin, Proc. Natl. Acad. Sci. USA 89 (1992) 7674-7677.
3. J.S. Stamler, D.I. Simon, J.A. Osborne, M.E. Mullins, O. Jaraki, T. Michel, D.J. Singel, J. Loscalzo, S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds, Proc. Natl. Acad. Sci. USA 89 (1992) 444-448.
4. C. Nathan, Q.W. Xie, Nitric oxide synthases: roles, tolls, and controls, Cell 78 (1994) 915-918.
5. H. Sun, C.H. Charles, L.F. Lau, N.K. Tonks, MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo, Cell 75 (1993) 487-493.
6. M. Camps, A. Nichols, S. Arkinstall, Dual specificity phosphatases: a gene family for control of MAP kinase function, Faseb J. 14 (2000) 6- 16.
7. T. Boutros, E. Chevet, P. Metrakos, Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: roles in cell growth, death, and cancer, Pharmacol. Rev. 60 (2008) 261-310.
8. A. Alonso, J. Sasin, N. Bottini, I. Friedberg, I. Friedberg, A. Osterman, A. Godzik, T. Hunter, J. Dixon, T. Mustelin, Protein tyrosine phosphatases in the human genome, Cell 117 (2004) 699-711.
9. H. Kamata, S. Honda, S. Maeda, L. Chang, H. Hirata, M. Karin, Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases, Cell 120 (2005) 649-661.
10. J.M. Brondello, J. Pouyssegur, F.R. McKenzie, Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylation, Science 286 (1999) 2514-2517.
11. Y.W. Lin, J.L. Yang, Cooperation of ERK and SCFSkp2 for MKP-1 destruction provides a positive feedback regulation of proliferating signaling, J. Biol. Chem. 281 (2006) 915-926.
12. G.S. Wu, Role of mitogen-activated protein kinase phosphatases (MKPs) in cancer, Cancer Metastasis Rev. 26 (2007) 579-585.
13. Z. Wang, J. Xu, J.Y. Zhou, Y. Liu, G.S. Wu, Mitogen-activated protein kinase phosphatase-1 is required for cisplatin resistance, Cancer Res. 66 (2006) 8870-8877.
14. J. Wang, J.Y. Zhou, G.S. Wu, ERK-dependent MKP-1-mediated cisplatin resistance in human ovarian cancer cells, Cancer Res. 67 (2007) 11933-11941.
15. Z. Wang, N. Cao, D. Nantajit, M. Fan, Y. Liu, J.J. Li, Mitogen-activated protein kinase phosphatase-1 represses c-Jun NH2-terminal kinasemediated apoptosis via NF-kappaB regulation, J. Biol. Chem. 283 (2008) 21011-21023.
16. H.Y. Wang, Z. Cheng, C.C. Malbon, Overexpression of mitogenactivated protein kinase phosphatases MKP1, MKP2 in human breast cancer, Cancer Lett. 191 (2003) 229-237.
17. M. Loda, P. Capodieci, R. Mishra, H. Yao, C. Corless, W. Grigioni, Y. Wang, C. Magi-Galluzzi, P.J. Stork, Expression of mitogen-activated protein kinase phosphatase-1 in the early phases of human epithelial carcinogenesis, Am. J. Pathol. 149 (1996) 1553-1564.
18. C. Denkert, W.D. Schmitt, S. Berger, A. Reles, S. Pest, A. Siegert, W. Lichtenegger, M. Dietel, S. Hauptmann, Expression of mitogenactivated protein kinase phosphatase-1 (MKP-1) in primary human ovarian carcinoma, Int. J. Cancer 102 (2002) 507-513.
19. B. Fitzpatrick, M. Mehibel, R.L. Cowen, I.J. Stratford, iNOS as a therapeutic target for treatment of human tumors, Nitric Oxide 19 (2008) 217-224.
20. S.M. Keyse, E.A. Emslie, Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase, Nature 359 (1992) 644-647.
21. C.C. Franklin, S. Srikanth, A.S. Kraft, Conditional expression of mitogen-activated protein kinase phosphatase-1, MKP-1, is cytoprotective against UV-induced apoptosis, Proc. Natl. Acad. Sci. USA 95 (1998) 3014-3019.
22. S. Chattopadhyay, R. Machado-Pinilla, C. Manguan-Garcia, C. Belda-Iniesta, C. Moratilla, P. Cejas, J.A. Fresno-Vara, J. de Castro-Carpeno, E. Casado, M. Nistal, M. Gonzalez-Baron, R. Perona, MKP1/CL100 controls tumor growth and sensitivity to cisplatin in non-smallcell lung cancer, Oncogene 25 (2006) 3335-3345.
23. J. Wang, D.P. Yin, Y.X. Liu, R. Baer, Y. Yin, Dual specificity phosphatase 1/CL100 is a direct transcriptional target of E2F-1 in the apoptotic response to oxidative stress, Cancer Res. 67 (2007) 6737-6744.
24. J. Li, M. Gorospe, D. Hutter, J. Barnes, S.M. Keyse, Y. Liu, Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation, Mol. Cell Biol. 21 (2001) 8213-8224.
25. K. Sandau, B. Brune, The dual role of S-nitrosoglutathione (GSNO) during thymocyte apoptosis, Cell. Signal. 8 (1996) 173-177.
26. D. Bordo, P. Bork, The rhodanese/Cdc25 phosphatase superfamily. Sequence-structure-function relations, EMBO Rep. 3 (2002) 741- 746.
27. C.H. Charles, A.S. Abler, L.F. Lau, cDNA sequence of a growth factorinducible immediate early gene and characterization of its encoded protein, Oncogene 7 (1992) 187-190.
28. T. Noguchi, R. Metz, L. Chen, M.G. Mattei, D. Carrasco, R. Bravo, Structure, mapping, and expression of erp, a growth factor-inducible gene encoding a nontransmembrane protein tyrosine phosphatase, and effect of ERP on cell growth, Mol. Cell Biol. 13 (1993) 5195- 5205.
29. K. Kondoh, K. Sunadome, E. Nishida, Notch signaling suppresses p38 MAPK activity via induction of MKP-1 in myogenesis, J. Biol. Chem. 282 (2007) 3058-3065.
30. J. Yaglom, C. O'Callaghan-Sunol, V. Gabai, M.Y. Sherman, Inactivation of dual-specificity phosphatases is involved in the regulation of extracellular signal-regulated kinases by heat shock and hsp72, Mol. Cell Biol. 23 (2003) 3813-3824.
31. G.W. Small, Y.Y. Shi, L.S. Higgins, R.Z. Orlowski, Mitogen-activated protein kinase phosphatase-1 is a mediator of breast cancer chemoresistance, Cancer Res. 67 (2007) 4459-4466.
32. F. Li, P. Sonveaux, Z.N. Rabbani, S. Liu, B. Yan, Q. Huang, Z. Vujaskovic, M.W. Dewhirst, C.Y. Li, Regulation of HIF-1alpha stability through Snitrosylation, Mol. Cell 26 (2007) 63-74.
33. A. Nemec, Z. Pavlica, M. Petelin, D.A. Crossley, M. Sentjurc, A. Jerin, D. Erzen, I. Zdovc, T. Hitti, U. Skaleric, Systemic use of selective iNOS inhibitor 1400W or non-selective NOS inhibitor l-NAME differently affects systemic nitric oxide formation after oral Porphyromonas gingivalis inoculation in mice, Arch. Oral Biol. 55 (2010) 509-514.
34. K.H. Lim, B.B. Ancrile, D.F. Kashatus, C.M. Counter, Tumour maintenance is mediated by eNOS, Nature 452 (2008) 646-649.
35. M.D. Fesinmeyer, V. Mehta, D. Blough, L. Tock, S.D. Ramsey, Effect of radiotherapy interruptions on survival in medicare enrollees with local and regional head-and-neck cancer, Int. J. Radiat. Oncol. Biol. Phys. 78 (2010) 675-681.
36. A. Argiris, D.E. Heron, R.P. Smith, S. Kim, M.K. Gibson, S.Y. Lai, B.F. Branstetter, D.M. Posluszny, L. Wang, R.R. Seethala, S. Dacic, W. Gooding, J.R. Grandis, J.T. Johnson, R.L. Ferris, Induction docetaxel, cisplatin, and cetuximab followed by concurrent radiotherapy, cisplatin, and cetuximab and maintenance cetuximab in patients with locally advanced head and neck cancer, J. Clin. Oncol. 28 (2010) 5294-5300.