-
1
-
-
0343503018
-
High prevalence of the thermolabile methylenetetrahydrofolate reductase variant in Mexico: A country with a very high prevalence of neural tube defects
-
DOI 10.1006/mgme.1999.2939
-
Mutchinick OM, López MA, Luna L, Waxman J, Babinsky VE, Ryvemce Collaborative Group: High prevalence of the thermolabile methylenetetrahydrofolate reductase variant in Mexico: a country with a very high prevalence of neural tube defects. Mol Genet Metab 1999; 68: 461-467. (Pubitemid 30043552)
-
(1999)
Molecular Genetics and Metabolism
, vol.68
, Issue.4
, pp. 461-467
-
-
Mutchinick, O.M.1
Lopez, M.A.2
Luna, L.3
Waxman, J.4
Babinsky, V.E.5
Berlanga, O.M.6
Carrillo, M.L.7
Cuevas, M.8
Diaz, C.9
Jimenez, C.10
Lopez, S.11
Macias, M.A.12
Perez, J.13
Valdes, J.M.14
-
2
-
-
55449092833
-
Association of homocysteinemia with high concentrations of serum insulin and uric acid in Brazilian subjects with metabolic syndrome genotyped for C677T polymorphism in the methylenetetrahydrofolate reductase gene
-
Uehara SK, Rosa G: Association of homocysteinemia with high concentrations of serum insulin and uric acid in Brazilian subjects with metabolic syndrome genotyped for C677T polymorphism in the methylenetetrahydrofolate reductase gene. Nutr Res 2008; 28: 760-766.
-
(2008)
Nutr Res
, vol.28
, pp. 760-766
-
-
Uehara, S.K.1
Rosa, G.2
-
3
-
-
0029049553
-
A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
-
Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG, Boers GJH, den Heijer M, Kluijtmans LAJ, van den Heuvel LP, Rozen R: A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 1995; 10: 111-113.
-
(1995)
Nat Genet
, vol.10
, pp. 111-113
-
-
Frosst, P.1
Blom, H.J.2
Milos, R.3
Goyette, P.4
Sheppard, C.A.5
Matthews, R.G.6
Boers, G.J.H.7
Den Heijer, M.8
Kluijtmans, L.A.J.9
Van Den Heuvel, L.P.10
Rozen, R.11
-
4
-
-
0030476385
-
Common mutation in methylenetetrahydrofolate reductase: Correlation with homocysteine metabolism and late-onset vascular disease
-
Deloughery TG, Evans A, Sadeghi A, Mc- Williams J, Henner WD, Taylor LM, Press RD: Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine metabolism and late-onset vascular disease. Circulation 1996; 94: 3074-3078. (Pubitemid 26427468)
-
(1996)
Circulation
, vol.94
, Issue.12
, pp. 3074-3078
-
-
Deloughery, T.G.1
Evans, A.2
Sadeghi, A.3
McWilliams, J.4
Henner, W.D.5
Taylor Jr., L.M.6
Press, R.D.7
-
5
-
-
0029738540
-
The common 'thermolabile' variant of methylene tetrahydrofolate reductase is a major determinant of mild hyperhomocysteinaemia
-
Harmon DL, Woodside JV, Yarnell JW, McMaster D, Young I, McCrum E, Gey K, Whitehead A, Evans AE: The common 'thermolabile'variant of methylenetetrahydrofolate reductase is a major determinant of mild hyperhomocysteinaemia. Q J Med 1996; 89: 571-577. (Pubitemid 26278868)
-
(1996)
QJM - Monthly Journal of the Association of Physicians
, vol.89
, Issue.8
, pp. 571-577
-
-
Harmon, D.L.1
Woodside, J.V.2
Yarnell, J.W.G.3
McMaster, D.4
Young, I.S.5
McCrum, E.E.6
Gey, K.F.7
Whitehead, A.S.8
Evans, A.E.9
-
6
-
-
0030027668
-
Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations
-
Jacques PF, Bostom AG, Williams RR, Ellison RC, Eckfeldt JH, Rosenberg IH, Selhub J, Rozen R: Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation1996; 93: 7-9. (Pubitemid 26006560)
-
(1996)
Circulation
, vol.93
, Issue.1
, pp. 7-9
-
-
Jacques, P.F.1
Bostom, A.G.2
Williams, R.R.3
Ellison, R.C.4
Eckfeldt, J.H.5
Rosenberg, I.H.6
Selhub, J.7
Rozen, R.8
-
7
-
-
0029806746
-
Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians
-
Ma J, Stampfer MJ, Hennekens CH, Frosst P, Selhub J, Horsford J, Malinow MR, Willett WC, Rozen R: Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians. Circulation 1996; 94:2410-2416. (Pubitemid 26403566)
-
(1996)
Circulation
, vol.94
, Issue.10
, pp. 2410-2416
-
-
Ma, J.1
Stampfer, M.J.2
Hennekens, C.H.3
Frosst, P.4
Selhub, J.5
Horsford, J.6
Rene, M.M.7
Willett, W.C.8
Rozen, R.9
-
8
-
-
0030975769
-
The effects of folic acid supplementation on plasma total homocysteine are modulated by multivitamin use and methylenetetrahydrofolate reductase genotypes
-
Malinow MR, Nieto FJ, Kruger WD, Duell PB, Hess DL, Gluckman RA, Block PC, Holzgang CR, Anderson PH, Seltzer D, Upson B, Lin QR: The effects of folic acid supplementation on plasma total homocysteine are modulated by multivitamin use and methylenetetrahydrofolate reductase genotypes. Arterioscler Thromb Vasc Biol 1997; 17:1157-1162. (Pubitemid 27260337)
-
(1997)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.17
, Issue.6
, pp. 1157-1162
-
-
Malinow, M.R.1
Nieto, F.J.2
Kruger, W.D.3
Duell, P.B.4
Hess, D.L.5
Gluckman, R.A.6
Block, P.C.7
Holzgang, C.R.8
Anderson, P.H.9
Seltzer, D.10
Upson, B.11
Lin, Q.R.12
-
9
-
-
0030811670
-
Myocardial infarction in young women in relation to plasma total homocysteine, folate, and a common variant in the methylenetetrahydrofolate reductase gene
-
Schwartz SM, Siscovick DS, Malinow MR, Rosendaal FR, Beverly RK, Hess DL, Psaty BM, longstreth WT Jr, Koepsell TD, Raghunathan TE, Reitsma PH: Myocardial infarction in young women in relation to plasma total homocysteine, folate, and a common variant in the methylenetetrahydrofolate reductase gene. Circulation 1997; 96: 412-417. (Pubitemid 27329413)
-
(1997)
Circulation
, vol.96
, Issue.2
, pp. 412-417
-
-
Schwartz, S.M.1
Siscovick, D.S.2
Malinow, M.R.3
Rosendaal, F.R.4
Beverly, R.K.5
Hess, D.L.6
Psaty, B.M.7
Longstreth Jr., W.T.8
Koepsell, T.D.9
Raghunathan, T.E.10
Reitsma, P.H.11
-
10
-
-
0030612756
-
The 677cT mutation in the methylenetetrahydrofolate reductase gene: Associations with plasma total homocysteine levels and risk of coronary atherosclerotic disease
-
DOI 10.1016/S0021-9150(97)00084-1, PII S0021915097000841
-
Verhoef P, Kok FJ, Kluijtmans LA, Blom HJ, Refsum H, Ueland PM, Kruyssen DACM: The 677CT mutation in the methylenetetrahydrofolate reductase gene: associations with plasma total homocysteine levels and risk of coronary atherosclerotic disease. Atherosclerosis 1997; 132: 105-113. (Pubitemid 27306745)
-
(1997)
Atherosclerosis
, vol.132
, Issue.1
, pp. 105-113
-
-
Verhoef, P.1
Kok, F.J.2
Kluijtmans, L.A.J.3
Blom, H.J.4
Refsum, H.5
Ueland, P.M.6
Kruyssen, D.A.C.M.7
-
11
-
-
0030845376
-
Methylenetetrahydrofolate reductase (MTHFR) mutation, homocyst(e)ine, and coronary artery disease [7] (multiple letters)
-
Wilcken DEL, Wang XL, Wilcken B: Methylenetetrahydrofolate reductase (MTHFR) mutation, homocyst(e)ine, and coronary artery disease. Circulation 1997; 96: 2738-2740. (Pubitemid 27451376)
-
(1997)
Circulation
, vol.96
, Issue.8
, pp. 2738-2740
-
-
Wilcken, D.E.L.1
Xing, L.W.2
Wilcken, B.3
Ma, J.4
Hennekens, C.H.5
Stampfer, M.6
-
12
-
-
0022471265
-
Protein-bound homocyst(e)ine. A possible risk factor for coronary artery disease
-
Kang SS, Wong PWK, Cook HY, Norusis M, Messer JV: Protein-bound homocysteine: a possible risk factor for coronary artery disease. J Clin Invest 1986; 77: 1482-1486. (Pubitemid 16047091)
-
(1986)
Journal of Clinical Investigation
, vol.77
, Issue.5
, pp. 1482-1486
-
-
Kang, S.-S.1
Wong, P.W.K.2
Cook, H.Y.3
-
13
-
-
0031831064
-
Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine and other risk factors for vascular disease
-
DOI 10.1016/S0021-9150(98)00079-3, PII S0021915098000793
-
Motti C, Gnasso A, Bernardini S, Massoud R, Pastore A, Rampa P, Federici G, Cortese C: Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine and other risk factors for vascular disease. Atherosclerosis 1998; 139: 377-383. (Pubitemid 28361823)
-
(1998)
Atherosclerosis
, vol.139
, Issue.2
, pp. 377-383
-
-
Motti, C.1
Gnasso, A.2
Bernardini, S.3
Massoud, R.4
Pastore, A.5
Rampa, P.6
Federici, G.7
Cortese, C.8
-
14
-
-
0001530462
-
Hyperuricemia and gout
-
Scriver CR, Beaudet AL, Sly WS, Valle D (eds): New York, McGraw-Hill
-
Beckler MA, Roessler BJ: Hyperuricemia and gout; in Scriver CR, Beaudet AL, Sly WS, Valle D (eds): The Metabolic Basis of Inherited Disease. New York, McGraw-Hill, 1995, pp 1655-1677.
-
(1995)
The Metabolic Basis of Inherited Disease
, pp. 1655-1677
-
-
Beckler, M.A.1
Roessler, B.J.2
-
15
-
-
0033928273
-
The C677T mutation in the methylene tetrahydrofolate reductase gene increases serum uric in elderly men
-
Zuo M, Nishio H, Lee MJ, Maejima K, Mimura S, Sumino K: The C677T mutation in the methylene tetrahydrofolate reductase gene increases serum uric acid in elderly men. J Hum Genet 2000; 45: 257-262. (Pubitemid 30482989)
-
(2000)
Journal of Human Genetics
, vol.45
, Issue.4
, pp. 257-262
-
-
Zuo, M.1
Nishio, H.2
Lee, M.J.3
Maejima, K.4
Mimura, S.5
Sumino, K.6
-
16
-
-
2342628517
-
The C677 mutation in methylene tetrahydrofolate reductase gene: Correlation with uric acid and cardiovascular risk factors in elderly Korean men
-
Hong YS, Lee MJ, Kim KH, Lee SH, Lee YH, Kim BG, Jeong B, Yoon HR, Nishio H, Kim JY: The C677 mutation in methylene tetrahydrofolate reductase gene: correlation with uric acid and cardiovascular risk factors in elderly Korean men. J Korean Med Sci 2004; 19: 209-213. (Pubitemid 38591793)
-
(2004)
Journal of Korean Medical Science
, vol.19
, Issue.2
, pp. 209-213
-
-
Hong, Y.S.1
Lee, M.J.2
Kim, K.H.3
Lee, S.H.4
Lee, Y.H.5
Kim, B.G.6
Jeong, B.7
Yoon, H.R.8
Nishio, H.9
Kim, J.Y.10
-
17
-
-
84862791063
-
Polymorphisms of methylenetetrahydrofolate reductase C677T and hyperuricemia in males
-
Yao H, Ding LL, Wang XM, Xu FL: Polymorphisms of methylenetetrahydrofolate reductase C677T and hyperuricemia in males. Ai Bian Ji Bian Tu Bian 2007; 19: 50-52.
-
(2007)
Ai Bian Ji Bian Tu Bian
, vol.19
, pp. 50-52
-
-
Yao, H.1
Ding, L.L.2
Wang, X.M.3
Xu, F.L.4
-
18
-
-
34447514242
-
Association of methylenetetrahydrofolate reductase (C677T) polymorphism with hyperuricemia
-
Golbahar J, Aminzadeh MA, Al-Shboul QM, Kassab S, Rezaian GR: Association of methylenetetrahydrofolate reductase (C677T) polymorphism with hyperuricemia. Nutr Metab Cardiovasc Dis 2006; 17: 462-467.
-
(2006)
Nutr Metab Cardiovasc Dis
, vol.17
, pp. 462-467
-
-
Golbahar, J.1
Aminzadeh, M.A.2
Al-Shboul, Q.M.3
Kassab, S.4
Rezaian, G.R.5
-
19
-
-
84862822528
-
The association of methylenetetrahydrofolate reductase (MTHFR) gene C677T mutation with hyperuricemia
-
Shi HY, Dong YH, Nan HT, Qian WW, Qian RL: The association of methylenetetrahydrofolate reductase (MTHFR) gene C677T mutation with hyperuricemia. Chin J Diabetes 2006; 14: 178-181.
-
(2006)
Chin J Diabetes
, vol.14
, pp. 178-181
-
-
Shi, H.Y.1
Dong, Y.H.2
Nan, H.T.3
Qian, W.W.4
Qian, R.L.5
-
20
-
-
29644439699
-
Polymorphism of methylenetetrahydrofolate reductase gene (C677T MTHFR) is not a confounding factor of the relationship between serum uric acid level and the prevalence of hypertension in Japanese men
-
DOI 10.1253/circj.70.83
-
Lwin H, Yokoyama T, Yoshiike N, Saito K, Yamamoto A, Date C, Tanaka H: Polymorphism of methylenetetrahydrofolate reductase gene (C677T MTHFR) is not a confounding factor of the relationship between serum uric acid level and the prevalence of hypertension in Japanese men. Circ J 2006; 70: 83-87. (Pubitemid 43021239)
-
(2006)
Circulation Journal
, vol.70
, Issue.1
, pp. 83-87
-
-
Lwin, H.1
Yokoyama, T.2
Yoshiike, N.3
Saito, K.4
Yamamoto, A.5
Date, C.6
Tanaka, H.7
-
21
-
-
44449158176
-
Definition and classification of hyperuricemia
-
Yamamoto T: Definition and classification of hyperuricemia. Nippon Rinsho 2008; 66:636-640.
-
(2008)
Nippon Rinsho
, vol.66
, pp. 636-640
-
-
Yamamoto, T.1
-
22
-
-
0029655527
-
Nutritional ecogenetics: Homocysteine- related arteriosclerotic vascular disease, neural tube defects, and folic acid
-
Motulsky AG: Nutritional ecogenetics: homocysteine- related arteriosclerotic vascular disease, neural tube defects, and folic acid. Am J Hum Genet 1996; 58: 17-20.
-
(1996)
Am J Hum Genet
, vol.58
, pp. 17-20
-
-
Motulsky, A.G.1
-
23
-
-
41049093347
-
The combination of estimates from different experiments
-
Cochran WG: The combination of estimates from different experiments. Biometrics 1954;10: 101-129.
-
(1954)
Biometrics
, vol.10
, pp. 101-129
-
-
Cochran, W.G.1
-
24
-
-
0041876133
-
Measuring inconsistency in meta-analyses
-
Higgins JP, Thompson SG, Deeks JJ, Altman DG: Measuring inconsistency in meta-analyses. BMJ 2003; 327: 557-560. (Pubitemid 37088507)
-
(2003)
British Medical Journal
, vol.327
, Issue.7414
, pp. 557-560
-
-
Higgins, J.P.T.1
Thompson, S.G.2
Deeks, J.J.3
Altman, D.G.4
-
25
-
-
0000976601
-
Meta-analysis, funnel plots and sensitivity analysis
-
DOI 10.1093/biostatistics/1.3.247
-
Copas J, Shi JQ: Meta-analysis, funnel plots and sensitivity analysis. Biostatistics 2000; 1:247-262. (Pubitemid 33213534)
-
(2000)
Biostatistics Oxford
, vol.1
, Issue.3
, pp. 247-262
-
-
Copas, J.1
Shi, J.Q.2
-
26
-
-
0035859525
-
Systematic reviews in health care: Investigating and dealing with publication and other biases in meta-analysis
-
Sterne JA, Egger M, Smith GD: Systematic reviews in health care: investigating and dealing with publication and other biases in meta-analysis. BMJ 2001; 323: 101-105. (Pubitemid 32681979)
-
(2001)
British Medical Journal
, vol.323
, Issue.7304
, pp. 101-105
-
-
Sterne, J.A.C.1
Egger, M.2
Smith, G.D.3
-
27
-
-
41549094002
-
Methylenetetrahydrofolate reductase gene polymorphisms and lung cancer: A meta-analysis
-
Mao R, Fan Y, Jin Y, Bai J, Fu S: Methylenetetrahydrofolate reductase gene polymorphisms and lung cancer: a meta-analysis. J Hum Genet 2008; 53: 340-348.
-
(2008)
J Hum Genet
, vol.53
, pp. 340-348
-
-
Mao, R.1
Fan, Y.2
Jin, Y.3
Bai, J.4
Fu, S.5
-
28
-
-
48249122168
-
Funnel plots in meta- analysis
-
Sterne JA, Harbord RM: Funnel plots in meta- analysis. Stata J 2004; 2: 127-141.
-
(2004)
Stata J
, vol.2
, pp. 127-141
-
-
Sterne, J.A.1
Harbord, R.M.2
-
29
-
-
0034047615
-
Case-control association studies for the genetics of complex respiratory diseases
-
Silverman EK, Palmer LJ: Case-control association studies for the genetics of complex respiratory diseases. Am J Respir Cell Mol Biol 2000; 22: 672-675.
-
(2000)
Am J Respir Cell Mol Biol
, vol.22
, pp. 672-675
-
-
Silverman, E.K.1
Palmer, L.J.2
-
30
-
-
0036942338
-
Positive results in association studies are associated with departure from Hardy-Weinberg equilibrium: Hint for genotyping error?
-
DOI 10.1007/s00439-002-0819-y
-
Xu J, Turner A, Little J, Bleecker ER, Meyers DA: Positive results in association studies are associated with departure from Hardy-Weinberg equilibrium: hint for genotyping error? Hum Genet 2002; 111: 573-574. (Pubitemid 36075091)
-
(2002)
Human Genetics
, vol.111
, Issue.6
, pp. 573-574
-
-
Xu, J.1
Turner, A.2
Little, J.3
Bleecker, E.R.4
Meyers, D.A.5
-
31
-
-
0020506022
-
Plasma lipids in twins. Environmental and genetic influences
-
Whitfield JB, Martin NG: Plasma lipids in twins. Environmental and genetic influences. Atherosclerosis 1983; 48: 265-277. (Pubitemid 13048864)
-
(1983)
Atherosclerosis
, vol.48
, Issue.3
, pp. 265-277
-
-
Whitfield, J.B.1
Martin, N.G.2
-
33
-
-
0023831048
-
Plasma uric acid level and its association with diabetes mellitus and some biologic parameters in a biracial population of Fiji
-
Tuomilehto J, Zimmet P, Wolf E, Taylor R, Ram P, King H: Plasma uric acid level and its association with diabetes mellitus and some biologic parameters in a biracial population of Fiji. Am J Epidemiol 1988; 127: 321-336. (Pubitemid 18056385)
-
(1988)
American Journal of Epidemiology
, vol.127
, Issue.2
, pp. 321-336
-
-
Tuomilehto, J.1
Zimmet, P.2
Wolf, E.3
Taylor, R.4
Ram, P.5
King, H.6
-
34
-
-
0014078409
-
The clinical significance of hyperuricemia
-
Seegmiller JE: The clinical significance of hyperuricemia. Med Ann Dist Columbia 1967; 36: 215-218.
-
(1967)
Med Ann Dist Columbia
, vol.36
, pp. 215-218
-
-
Seegmiller, J.E.1
-
35
-
-
0015805865
-
The kinetics of intramolecular distribution of 15N in uric acid after administration of (15N) glycine. A reappraisal of the significance of preferential labeling of N-(3+9) of uric acid in primary gout
-
Sperling O, Wyngaarden JB, Starmer CF: The kinetics of intramolecular distribution of 15N in uric acid after administration of (15N) glycine. A reappraisal of the significance of preferential labeling of N-(3+9) of uric acid in primary gout. J Clin Invest 1973; 52: 2468-2485.
-
(1973)
J Clin Invest
, vol.52
, pp. 2468-2485
-
-
Sperling, O.1
Wyngaarden, J.B.2
Starmer, C.F.3
-
36
-
-
0019801907
-
A gouty family with increased phosphoribosylpyrophosphate synthetase activity: Case reports, familial studies, and kinetic studies of the abnormal enzyme
-
Akaoka I, Fujimori S, Kamatani N, Takeuchi F, Yano E, Nishida Y, Hashimoto A, Horiuchi Y: A gouty family with increased phosphoribosylpyrophosphate synthetase activity: case reports, familial studies, and kinetic studies of the abnormal enzyme. J Rheumatol 1981; 8: 563-574. (Pubitemid 12244877)
-
(1981)
Journal of Rheumatology
, vol.8
, Issue.4
, pp. 563-574
-
-
Akaoka, I.1
Fujimori, S.2
Kamatani, N.3
-
37
-
-
0034630917
-
Serum uric acid and cardiovascular mortality: The NHANES I Epidemiologic Follow-up Study, 1971-1992
-
Fang J, Alderman MH: Serum uric acid and cardiovascular mortality the NHANES I epidemiologic follow-up study, 1971-1992. National Health and Nutrition Examination Survey. JAMA 2000; 283: 2404-2410. (Pubitemid 30257539)
-
(2000)
Journal of the American Medical Association
, vol.283
, Issue.18
, pp. 2404-2410
-
-
Fang, J.1
Alderman, M.H.2
-
38
-
-
0037332145
-
Publication bias and meta analysis
-
DOI 10.1097/00004872-200302000-00007
-
Schork MA: Publication bias and meta analysis. J Hypertens 2003; 21: 243-245. (Pubitemid 36269687)
-
(2003)
Journal of Hypertension
, vol.21
, Issue.2
, pp. 243-245
-
-
Schork, M.A.1
|