메뉴 건너뛰기




Volumn 60, Issue 1, 2012, Pages 44-51

Meta-analysis of the association of the C677T polymorphism of the methylenetetrahydrofolate reductase gene with hyperuricemia

Author keywords

C677T; Hyperuricemia; Meta analysis; MTHFR; Polymorphisms

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CYTOSINE; THYMINE; URIC ACID;

EID: 84862821307     PISSN: 02506807     EISSN: 14219697     Source Type: Journal    
DOI: 10.1159/000335698     Document Type: Review
Times cited : (9)

References (38)
  • 2
    • 55449092833 scopus 로고    scopus 로고
    • Association of homocysteinemia with high concentrations of serum insulin and uric acid in Brazilian subjects with metabolic syndrome genotyped for C677T polymorphism in the methylenetetrahydrofolate reductase gene
    • Uehara SK, Rosa G: Association of homocysteinemia with high concentrations of serum insulin and uric acid in Brazilian subjects with metabolic syndrome genotyped for C677T polymorphism in the methylenetetrahydrofolate reductase gene. Nutr Res 2008; 28: 760-766.
    • (2008) Nutr Res , vol.28 , pp. 760-766
    • Uehara, S.K.1    Rosa, G.2
  • 4
    • 0030476385 scopus 로고    scopus 로고
    • Common mutation in methylenetetrahydrofolate reductase: Correlation with homocysteine metabolism and late-onset vascular disease
    • Deloughery TG, Evans A, Sadeghi A, Mc- Williams J, Henner WD, Taylor LM, Press RD: Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine metabolism and late-onset vascular disease. Circulation 1996; 94: 3074-3078. (Pubitemid 26427468)
    • (1996) Circulation , vol.94 , Issue.12 , pp. 3074-3078
    • Deloughery, T.G.1    Evans, A.2    Sadeghi, A.3    McWilliams, J.4    Henner, W.D.5    Taylor Jr., L.M.6    Press, R.D.7
  • 6
    • 0030027668 scopus 로고    scopus 로고
    • Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations
    • Jacques PF, Bostom AG, Williams RR, Ellison RC, Eckfeldt JH, Rosenberg IH, Selhub J, Rozen R: Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation1996; 93: 7-9. (Pubitemid 26006560)
    • (1996) Circulation , vol.93 , Issue.1 , pp. 7-9
    • Jacques, P.F.1    Bostom, A.G.2    Williams, R.R.3    Ellison, R.C.4    Eckfeldt, J.H.5    Rosenberg, I.H.6    Selhub, J.7    Rozen, R.8
  • 7
    • 0029806746 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians
    • Ma J, Stampfer MJ, Hennekens CH, Frosst P, Selhub J, Horsford J, Malinow MR, Willett WC, Rozen R: Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians. Circulation 1996; 94:2410-2416. (Pubitemid 26403566)
    • (1996) Circulation , vol.94 , Issue.10 , pp. 2410-2416
    • Ma, J.1    Stampfer, M.J.2    Hennekens, C.H.3    Frosst, P.4    Selhub, J.5    Horsford, J.6    Rene, M.M.7    Willett, W.C.8    Rozen, R.9
  • 10
    • 0030612756 scopus 로고    scopus 로고
    • The 677cT mutation in the methylenetetrahydrofolate reductase gene: Associations with plasma total homocysteine levels and risk of coronary atherosclerotic disease
    • DOI 10.1016/S0021-9150(97)00084-1, PII S0021915097000841
    • Verhoef P, Kok FJ, Kluijtmans LA, Blom HJ, Refsum H, Ueland PM, Kruyssen DACM: The 677CT mutation in the methylenetetrahydrofolate reductase gene: associations with plasma total homocysteine levels and risk of coronary atherosclerotic disease. Atherosclerosis 1997; 132: 105-113. (Pubitemid 27306745)
    • (1997) Atherosclerosis , vol.132 , Issue.1 , pp. 105-113
    • Verhoef, P.1    Kok, F.J.2    Kluijtmans, L.A.J.3    Blom, H.J.4    Refsum, H.5    Ueland, P.M.6    Kruyssen, D.A.C.M.7
  • 11
    • 0030845376 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase (MTHFR) mutation, homocyst(e)ine, and coronary artery disease [7] (multiple letters)
    • Wilcken DEL, Wang XL, Wilcken B: Methylenetetrahydrofolate reductase (MTHFR) mutation, homocyst(e)ine, and coronary artery disease. Circulation 1997; 96: 2738-2740. (Pubitemid 27451376)
    • (1997) Circulation , vol.96 , Issue.8 , pp. 2738-2740
    • Wilcken, D.E.L.1    Xing, L.W.2    Wilcken, B.3    Ma, J.4    Hennekens, C.H.5    Stampfer, M.6
  • 12
    • 0022471265 scopus 로고
    • Protein-bound homocyst(e)ine. A possible risk factor for coronary artery disease
    • Kang SS, Wong PWK, Cook HY, Norusis M, Messer JV: Protein-bound homocysteine: a possible risk factor for coronary artery disease. J Clin Invest 1986; 77: 1482-1486. (Pubitemid 16047091)
    • (1986) Journal of Clinical Investigation , vol.77 , Issue.5 , pp. 1482-1486
    • Kang, S.-S.1    Wong, P.W.K.2    Cook, H.Y.3
  • 13
    • 0031831064 scopus 로고    scopus 로고
    • Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine and other risk factors for vascular disease
    • DOI 10.1016/S0021-9150(98)00079-3, PII S0021915098000793
    • Motti C, Gnasso A, Bernardini S, Massoud R, Pastore A, Rampa P, Federici G, Cortese C: Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine and other risk factors for vascular disease. Atherosclerosis 1998; 139: 377-383. (Pubitemid 28361823)
    • (1998) Atherosclerosis , vol.139 , Issue.2 , pp. 377-383
    • Motti, C.1    Gnasso, A.2    Bernardini, S.3    Massoud, R.4    Pastore, A.5    Rampa, P.6    Federici, G.7    Cortese, C.8
  • 14
    • 0001530462 scopus 로고
    • Hyperuricemia and gout
    • Scriver CR, Beaudet AL, Sly WS, Valle D (eds): New York, McGraw-Hill
    • Beckler MA, Roessler BJ: Hyperuricemia and gout; in Scriver CR, Beaudet AL, Sly WS, Valle D (eds): The Metabolic Basis of Inherited Disease. New York, McGraw-Hill, 1995, pp 1655-1677.
    • (1995) The Metabolic Basis of Inherited Disease , pp. 1655-1677
    • Beckler, M.A.1    Roessler, B.J.2
  • 15
    • 0033928273 scopus 로고    scopus 로고
    • The C677T mutation in the methylene tetrahydrofolate reductase gene increases serum uric in elderly men
    • Zuo M, Nishio H, Lee MJ, Maejima K, Mimura S, Sumino K: The C677T mutation in the methylene tetrahydrofolate reductase gene increases serum uric acid in elderly men. J Hum Genet 2000; 45: 257-262. (Pubitemid 30482989)
    • (2000) Journal of Human Genetics , vol.45 , Issue.4 , pp. 257-262
    • Zuo, M.1    Nishio, H.2    Lee, M.J.3    Maejima, K.4    Mimura, S.5    Sumino, K.6
  • 17
    • 84862791063 scopus 로고    scopus 로고
    • Polymorphisms of methylenetetrahydrofolate reductase C677T and hyperuricemia in males
    • Yao H, Ding LL, Wang XM, Xu FL: Polymorphisms of methylenetetrahydrofolate reductase C677T and hyperuricemia in males. Ai Bian Ji Bian Tu Bian 2007; 19: 50-52.
    • (2007) Ai Bian Ji Bian Tu Bian , vol.19 , pp. 50-52
    • Yao, H.1    Ding, L.L.2    Wang, X.M.3    Xu, F.L.4
  • 19
    • 84862822528 scopus 로고    scopus 로고
    • The association of methylenetetrahydrofolate reductase (MTHFR) gene C677T mutation with hyperuricemia
    • Shi HY, Dong YH, Nan HT, Qian WW, Qian RL: The association of methylenetetrahydrofolate reductase (MTHFR) gene C677T mutation with hyperuricemia. Chin J Diabetes 2006; 14: 178-181.
    • (2006) Chin J Diabetes , vol.14 , pp. 178-181
    • Shi, H.Y.1    Dong, Y.H.2    Nan, H.T.3    Qian, W.W.4    Qian, R.L.5
  • 20
    • 29644439699 scopus 로고    scopus 로고
    • Polymorphism of methylenetetrahydrofolate reductase gene (C677T MTHFR) is not a confounding factor of the relationship between serum uric acid level and the prevalence of hypertension in Japanese men
    • DOI 10.1253/circj.70.83
    • Lwin H, Yokoyama T, Yoshiike N, Saito K, Yamamoto A, Date C, Tanaka H: Polymorphism of methylenetetrahydrofolate reductase gene (C677T MTHFR) is not a confounding factor of the relationship between serum uric acid level and the prevalence of hypertension in Japanese men. Circ J 2006; 70: 83-87. (Pubitemid 43021239)
    • (2006) Circulation Journal , vol.70 , Issue.1 , pp. 83-87
    • Lwin, H.1    Yokoyama, T.2    Yoshiike, N.3    Saito, K.4    Yamamoto, A.5    Date, C.6    Tanaka, H.7
  • 21
    • 44449158176 scopus 로고    scopus 로고
    • Definition and classification of hyperuricemia
    • Yamamoto T: Definition and classification of hyperuricemia. Nippon Rinsho 2008; 66:636-640.
    • (2008) Nippon Rinsho , vol.66 , pp. 636-640
    • Yamamoto, T.1
  • 22
    • 0029655527 scopus 로고    scopus 로고
    • Nutritional ecogenetics: Homocysteine- related arteriosclerotic vascular disease, neural tube defects, and folic acid
    • Motulsky AG: Nutritional ecogenetics: homocysteine- related arteriosclerotic vascular disease, neural tube defects, and folic acid. Am J Hum Genet 1996; 58: 17-20.
    • (1996) Am J Hum Genet , vol.58 , pp. 17-20
    • Motulsky, A.G.1
  • 23
    • 41049093347 scopus 로고
    • The combination of estimates from different experiments
    • Cochran WG: The combination of estimates from different experiments. Biometrics 1954;10: 101-129.
    • (1954) Biometrics , vol.10 , pp. 101-129
    • Cochran, W.G.1
  • 25
    • 0000976601 scopus 로고    scopus 로고
    • Meta-analysis, funnel plots and sensitivity analysis
    • DOI 10.1093/biostatistics/1.3.247
    • Copas J, Shi JQ: Meta-analysis, funnel plots and sensitivity analysis. Biostatistics 2000; 1:247-262. (Pubitemid 33213534)
    • (2000) Biostatistics Oxford , vol.1 , Issue.3 , pp. 247-262
    • Copas, J.1    Shi, J.Q.2
  • 26
    • 0035859525 scopus 로고    scopus 로고
    • Systematic reviews in health care: Investigating and dealing with publication and other biases in meta-analysis
    • Sterne JA, Egger M, Smith GD: Systematic reviews in health care: investigating and dealing with publication and other biases in meta-analysis. BMJ 2001; 323: 101-105. (Pubitemid 32681979)
    • (2001) British Medical Journal , vol.323 , Issue.7304 , pp. 101-105
    • Sterne, J.A.C.1    Egger, M.2    Smith, G.D.3
  • 27
    • 41549094002 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase gene polymorphisms and lung cancer: A meta-analysis
    • Mao R, Fan Y, Jin Y, Bai J, Fu S: Methylenetetrahydrofolate reductase gene polymorphisms and lung cancer: a meta-analysis. J Hum Genet 2008; 53: 340-348.
    • (2008) J Hum Genet , vol.53 , pp. 340-348
    • Mao, R.1    Fan, Y.2    Jin, Y.3    Bai, J.4    Fu, S.5
  • 28
    • 48249122168 scopus 로고    scopus 로고
    • Funnel plots in meta- analysis
    • Sterne JA, Harbord RM: Funnel plots in meta- analysis. Stata J 2004; 2: 127-141.
    • (2004) Stata J , vol.2 , pp. 127-141
    • Sterne, J.A.1    Harbord, R.M.2
  • 29
    • 0034047615 scopus 로고    scopus 로고
    • Case-control association studies for the genetics of complex respiratory diseases
    • Silverman EK, Palmer LJ: Case-control association studies for the genetics of complex respiratory diseases. Am J Respir Cell Mol Biol 2000; 22: 672-675.
    • (2000) Am J Respir Cell Mol Biol , vol.22 , pp. 672-675
    • Silverman, E.K.1    Palmer, L.J.2
  • 30
    • 0036942338 scopus 로고    scopus 로고
    • Positive results in association studies are associated with departure from Hardy-Weinberg equilibrium: Hint for genotyping error?
    • DOI 10.1007/s00439-002-0819-y
    • Xu J, Turner A, Little J, Bleecker ER, Meyers DA: Positive results in association studies are associated with departure from Hardy-Weinberg equilibrium: hint for genotyping error? Hum Genet 2002; 111: 573-574. (Pubitemid 36075091)
    • (2002) Human Genetics , vol.111 , Issue.6 , pp. 573-574
    • Xu, J.1    Turner, A.2    Little, J.3    Bleecker, E.R.4    Meyers, D.A.5
  • 31
    • 0020506022 scopus 로고
    • Plasma lipids in twins. Environmental and genetic influences
    • Whitfield JB, Martin NG: Plasma lipids in twins. Environmental and genetic influences. Atherosclerosis 1983; 48: 265-277. (Pubitemid 13048864)
    • (1983) Atherosclerosis , vol.48 , Issue.3 , pp. 265-277
    • Whitfield, J.B.1    Martin, N.G.2
  • 32
    • 0026548215 scopus 로고
    • Genetic control of the renal clearance of urate: A study of twins
    • Emmerson BT, Nagel SL, Duffy DL, Martin NG: Genetic control of the renal clearance of urate: a study of twins. Ann Rheum Dis 1992; 51: 375-377.
    • (1992) Ann Rheum Dis , vol.51 , pp. 375-377
    • Emmerson, B.T.1    Nagel, S.L.2    Duffy, D.L.3    Martin, N.G.4
  • 33
    • 0023831048 scopus 로고
    • Plasma uric acid level and its association with diabetes mellitus and some biologic parameters in a biracial population of Fiji
    • Tuomilehto J, Zimmet P, Wolf E, Taylor R, Ram P, King H: Plasma uric acid level and its association with diabetes mellitus and some biologic parameters in a biracial population of Fiji. Am J Epidemiol 1988; 127: 321-336. (Pubitemid 18056385)
    • (1988) American Journal of Epidemiology , vol.127 , Issue.2 , pp. 321-336
    • Tuomilehto, J.1    Zimmet, P.2    Wolf, E.3    Taylor, R.4    Ram, P.5    King, H.6
  • 34
    • 0014078409 scopus 로고
    • The clinical significance of hyperuricemia
    • Seegmiller JE: The clinical significance of hyperuricemia. Med Ann Dist Columbia 1967; 36: 215-218.
    • (1967) Med Ann Dist Columbia , vol.36 , pp. 215-218
    • Seegmiller, J.E.1
  • 35
    • 0015805865 scopus 로고
    • The kinetics of intramolecular distribution of 15N in uric acid after administration of (15N) glycine. A reappraisal of the significance of preferential labeling of N-(3+9) of uric acid in primary gout
    • Sperling O, Wyngaarden JB, Starmer CF: The kinetics of intramolecular distribution of 15N in uric acid after administration of (15N) glycine. A reappraisal of the significance of preferential labeling of N-(3+9) of uric acid in primary gout. J Clin Invest 1973; 52: 2468-2485.
    • (1973) J Clin Invest , vol.52 , pp. 2468-2485
    • Sperling, O.1    Wyngaarden, J.B.2    Starmer, C.F.3
  • 36
    • 0019801907 scopus 로고
    • A gouty family with increased phosphoribosylpyrophosphate synthetase activity: Case reports, familial studies, and kinetic studies of the abnormal enzyme
    • Akaoka I, Fujimori S, Kamatani N, Takeuchi F, Yano E, Nishida Y, Hashimoto A, Horiuchi Y: A gouty family with increased phosphoribosylpyrophosphate synthetase activity: case reports, familial studies, and kinetic studies of the abnormal enzyme. J Rheumatol 1981; 8: 563-574. (Pubitemid 12244877)
    • (1981) Journal of Rheumatology , vol.8 , Issue.4 , pp. 563-574
    • Akaoka, I.1    Fujimori, S.2    Kamatani, N.3
  • 37
    • 0034630917 scopus 로고    scopus 로고
    • Serum uric acid and cardiovascular mortality: The NHANES I Epidemiologic Follow-up Study, 1971-1992
    • Fang J, Alderman MH: Serum uric acid and cardiovascular mortality the NHANES I epidemiologic follow-up study, 1971-1992. National Health and Nutrition Examination Survey. JAMA 2000; 283: 2404-2410. (Pubitemid 30257539)
    • (2000) Journal of the American Medical Association , vol.283 , Issue.18 , pp. 2404-2410
    • Fang, J.1    Alderman, M.H.2
  • 38
    • 0037332145 scopus 로고    scopus 로고
    • Publication bias and meta analysis
    • DOI 10.1097/00004872-200302000-00007
    • Schork MA: Publication bias and meta analysis. J Hypertens 2003; 21: 243-245. (Pubitemid 36269687)
    • (2003) Journal of Hypertension , vol.21 , Issue.2 , pp. 243-245
    • Schork, M.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.