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Volumn 20, Issue 4, 2012, Pages 759-768

Myxoma virus sensitizes cancer cells to gemcitabine and is an effective oncolytic virotherapeutic in models of disseminated pancreatic cancer

Author keywords

[No Author keywords available]

Indexed keywords

GEMCITABINE; ONCOLYTIC MYXOMA VIRUS; ONCOLYTIC VIRUS; UNCLASSIFIED DRUG;

EID: 84862820881     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2011.293     Document Type: Article
Times cited : (51)

References (42)
  • 2
    • 0035165047 scopus 로고    scopus 로고
    • Gemcitabine: Progress in the treatment of pancreatic cancer
    • DOI 10.1159/000055290
    • Heinemann, V (2001). Gemcitabine: progress in the treatment of pancreatic cancer. Oncology 60: 8-18. (Pubitemid 32041425)
    • (2001) Oncology , vol.60 , Issue.1 , pp. 8-18
    • Heinemann, V.1
  • 4
    • 47949117602 scopus 로고    scopus 로고
    • Pancreatic cancer: From molecular pathogenesis to targeted therapy
    • Strimpakos, A, Saif, MW and Syrigos, KN (2008). Pancreatic cancer: from molecular pathogenesis to targeted therapy. Cancer Metastasis Rev 27: 495-522.
    • (2008) Cancer Metastasis Rev , vol.27 , pp. 495-522
    • Strimpakos, A.1    Saif, M.W.2    Syrigos, K.N.3
  • 6
    • 61449119672 scopus 로고    scopus 로고
    • Markers involved in resistance to cytotoxics and targeted therapeutics in pancreatic cancer
    • El Maalouf, G, Le Tourneau, C, Batty, GN, Faivre, S and Raymond, E (2009). Markers involved in resistance to cytotoxics and targeted therapeutics in pancreatic cancer. Cancer Treat Rev 35: 167-174.
    • (2009) Cancer Treat Rev , vol.35 , pp. 167-174
    • El Maalouf, G.1    Le Tourneau, C.2    Batty, G.N.3    Faivre, S.4    Raymond, E.5
  • 7
    • 34250197225 scopus 로고    scopus 로고
    • Combination chemotherapy in advanced pancreatic cancer: Time to raise the white flag?
    • DOI 10.1200/JCO.2006.09.9788
    • Welch, SA and Moore, MJ (2007). Combination chemotherapy in advanced pancreatic cancer: time to raise the white flag? J Clin Oncol 25: 2159-2161. (Pubitemid 46954636)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.16 , pp. 2159-2161
    • Welch, S.A.1    Moore, M.J.2
  • 8
    • 70350616252 scopus 로고    scopus 로고
    • Novel agents for the treatment of adenocarcinoma of the pancreas
    • Mackenzie, RP and McCollum, AD (2009). Novel agents for the treatment of adenocarcinoma of the pancreas. Expert Rev Anticancer Ther 9: 1473-1485.
    • (2009) Expert Rev Anticancer Ther , vol.9 , pp. 1473-1485
    • MacKenzie, R.P.1    McCollum, A.D.2
  • 9
    • 23944444807 scopus 로고    scopus 로고
    • The potential of oncolytic virus therapy for pancreatic cancer
    • DOI 10.1038/sj.cgt.7700830
    • Kasuya, H, Takeda, S, Nomoto, S and Nakao, A (2005). The potential of oncolytic virus therapy for pancreatic cancer. Cancer Gene Ther 12: 725-736. (Pubitemid 41208612)
    • (2005) Cancer Gene Therapy , vol.12 , Issue.9 , pp. 725-736
    • Kasuya, H.1    Takeda, S.2    Nomoto, S.3    Nakao, A.4
  • 10
    • 33846650370 scopus 로고    scopus 로고
    • Clinical trial results with oncolytic virotherapy: A century of promise, a decade of progress
    • DOI 10.1038/ncponc0736, PII NCPONC0736
    • Liu, TC, Galanis, E and Kirn, D (2007). Clinical trial results with oncolytic virotherapy: a century of promise, a decade of progress. Nat Clin Pract Oncol 4: 101-117. (Pubitemid 46189539)
    • (2007) Nature Clinical Practice Oncology , vol.4 , Issue.2 , pp. 101-117
    • Liu, T.-C.1    Galanis, E.2    Kirn, D.3
  • 11
    • 33749843288 scopus 로고    scopus 로고
    • Herpes simplex virus 1 (HSV-1) for cancer treatment
    • DOI 10.1038/sj.cgt.7700946, PII 7700946
    • Shen, Y and Nemunaitis, J (2006). Herpes simplex virus 1 (HSV-1) for cancer treatment. Cancer Gene Ther 13: 975-992. (Pubitemid 44564734)
    • (2006) Cancer Gene Therapy , vol.13 , Issue.11 , pp. 975-992
    • Shen, Y.1    Nemunaitis, J.2
  • 12
    • 27944497796 scopus 로고    scopus 로고
    • Oncolytic virotherapy for cancer treatment: Challenges and solutions
    • DOI 10.1002/jgm.800
    • Davis, JJ and Fang, B (2005). Oncolytic virotherapy for cancer treatment: challenges and solutions. J Gene Med 7: 1380-1389. (Pubitemid 41672396)
    • (2005) Journal of Gene Medicine , vol.7 , Issue.11 , pp. 1380-1389
    • Davis, J.J.1    Fang, B.2
  • 13
    • 34547218986 scopus 로고    scopus 로고
    • Oncolytic viruses in cancer therapy
    • DOI 10.1016/j.canlet.2007.02.002, PII S0304383507000468
    • Vähä-Koskela, MJ, Heikkilä, JE and Hinkkanen, AE (2007). Oncolytic viruses in cancer therapy. Cancer Lett 254: 178-216. (Pubitemid 47126688)
    • (2007) Cancer Letters , vol.254 , Issue.2 , pp. 178-216
    • Vaha-Koskela, M.J.V.1    Heikkila, J.E.2    Hinkkanen, A.E.3
  • 15
    • 67650675099 scopus 로고    scopus 로고
    • Pharmacologic and chemical adjuvants in tumor virotherapy
    • Alvarez-Breckenridge, C, Kaur, B and Chiocca, EA (2009). Pharmacologic and chemical adjuvants in tumor virotherapy. Chem Rev 109: 3125-3140.
    • (2009) Chem Rev , vol.109 , pp. 3125-3140
    • Alvarez-Breckenridge, C.1    Kaur, B.2    Chiocca, E.A.3
  • 17
    • 34748903753 scopus 로고    scopus 로고
    • Myxoma virus and oncolytic virotherapy: A new biologic weapon in the war against cancer
    • DOI 10.1517/14712598.7.9.1415
    • Stanford, MM and McFadden, G (2007). Myxoma virus and oncolytic virotherapy: a new biologic weapon in the war against cancer. Expert Opin Biol Ther 7: 1415-1425. (Pubitemid 47475657)
    • (2007) Expert Opinion on Biological Therapy , vol.7 , Issue.9 , pp. 1415-1425
    • Stanford, M.M.1    McFadden, G.2
  • 18
    • 14544284014 scopus 로고    scopus 로고
    • Poxvirus tropism
    • DOI 10.1038/nrmicro1099
    • McFadden, G (2005). Poxvirus tropism. Nat Rev Microbiol 3: 201-213. (Pubitemid 40298220)
    • (2005) Nature Reviews Microbiology , vol.3 , Issue.3 , pp. 201-213
    • McFadden, G.1
  • 19
    • 0014019579 scopus 로고
    • Absence of serological evidence of myxoma virus infection in humans exposed during an outbreak of myxomatosis
    • Jackson, EW, Dorn, CR, Saito, JK and McKercher, DG (1966). Absence of serological evidence of myxoma virus infection in humans exposed during an outbreak of myxomatosis. Nature 211: 313-314.
    • (1966) Nature , vol.211 , pp. 313-314
    • Jackson, E.W.1    Dorn, C.R.2    Saito, J.K.3    McKercher, D.G.4
  • 20
    • 0034104172 scopus 로고    scopus 로고
    • Adventures with poxviruses of vertebrates
    • DOI 10.1016/S0168-6445(00)00027-9, PII S0168644500000279
    • Fenner, F (2000). Adventures with poxviruses of vertebrates. FEMS Microbiol Rev 24: 123-133. (Pubitemid 30136439)
    • (2000) FEMS Microbiology Reviews , vol.24 , Issue.2 , pp. 123-133
    • Fenner, F.1
  • 21
    • 34147136559 scopus 로고    scopus 로고
    • Myxoma virus in the European rabbit: Interactions between the virus and its susceptible host
    • DOI 10.1051/vetres:2006054, Respiratory viruses of domestic animals
    • Stanford, MM, Werden, SJ and McFadden, G (2007). Myxoma virus in the European rabbit: interactions between the virus and its susceptible host. Vet Res 38: 299-318. (Pubitemid 46562409)
    • (2007) Veterinary Research , vol.38 , Issue.2 , pp. 299-318
    • Stanford, M.M.1    Werden, S.J.2    McFadden, G.3
  • 22
    • 76549086994 scopus 로고    scopus 로고
    • Myxoma virus virotherapy for glioma in immunocompetent animal models: Optimizing administration routes and synergy with rapamycin
    • Lun, X, Alain, T, Zemp, FJ, Zhou, H, Rahman, MM, Hamilton, MG et al. (2010). Myxoma virus virotherapy for glioma in immunocompetent animal models: optimizing administration routes and synergy with rapamycin. Cancer Res 70: 598-608.
    • (2010) Cancer Res , vol.70 , pp. 598-608
    • Lun, X.1    Alain, T.2    Zemp, F.J.3    Zhou, H.4    Rahman, M.M.5    Hamilton, M.G.6
  • 27
    • 33645240416 scopus 로고    scopus 로고
    • Infection of human cancer cells with myxoma virus requires Akt activation via interaction with a viral ankyrin-repeat host range factor
    • Wang, G, Barrett, JW, Stanford, M, Werden, SJ, Johnston, JB, Gao, X et al. (2006). Infection of human cancer cells with myxoma virus requires Akt activation via interaction with a viral ankyrin-repeat host range factor. Proc Natl Acad Sci USA 103: 4640-4645.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 4640-4645
    • Wang, G.1    Barrett, J.W.2    Stanford, M.3    Werden, S.J.4    Johnston, J.B.5    Gao, X.6
  • 28
    • 33847209578 scopus 로고    scopus 로고
    • M-T5, the ankyrin repeat, host range protein of myxoma virus, activates Akt and can be functionally replaced by cellular PIKE-A
    • Werden, SJ, Barrett, JW, Wang, G, Stanford, MM and McFadden, G (2007). M-T5, the ankyrin repeat, host range protein of myxoma virus, activates Akt and can be functionally replaced by cellular PIKE-A. J Virol 81: 2340-2348.
    • (2007) J Virol , vol.81 , pp. 2340-2348
    • Werden, S.J.1    Barrett, J.W.2    Wang, G.3    Stanford, M.M.4    McFadden, G.5
  • 29
    • 38149111916 scopus 로고    scopus 로고
    • The role of cell signaling in poxvirus tropism: The case of the M-T5 host range protein of myxoma virus
    • Werden, SJ and McFadden, G (2008). The role of cell signaling in poxvirus tropism: the case of the M-T5 host range protein of myxoma virus. Biochim Biophys Acta 1784: 228-237.
    • (2008) Biochim Biophys Acta , vol.1784 , pp. 228-237
    • Werden, S.J.1    McFadden, G.2
  • 30
    • 68949163770 scopus 로고    scopus 로고
    • Human cancer cells have specifically lost the ability to induce the synergistic state caused by tumor necrosis factor plus interferonbeta
    • Bartee, E and McFadden, G (2009). Human cancer cells have specifically lost the ability to induce the synergistic state caused by tumor necrosis factor plus interferonbeta. Cytokine 47: 199-205.
    • (2009) Cytokine , vol.47 , pp. 199-205
    • Bartee, E.1    McFadden, G.2
  • 32
    • 67650999217 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer
    • Arumugam, T, Ramachandran, V, Fournier, KF, Wang, H, Marquis, L, Abbruzzese, JL et al. (2009). Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer. Cancer Res 69: 5820-5828.
    • (2009) Cancer Res , vol.69 , pp. 5820-5828
    • Arumugam, T.1    Ramachandran, V.2    Fournier, K.F.3    Wang, H.4    Marquis, L.5    Abbruzzese, J.L.6
  • 33
    • 34548020722 scopus 로고    scopus 로고
    • Coadministration of a herpes simplex virus-2-based oncolytic virus and cyclophosphamide produces a synergistic antitumor effect and enhances tumor-specific immune responses
    • DOI 10.1158/0008-5472.CAN-07-1087
    • Li, H, Zeng, Z, Fu, X and Zhang, X (2007). Coadministration of a herpes simplex virus-2 based oncolytic virus and cyclophosphamide produces a synergistic antitumor effect and enhances tumor-specific immune responses. Cancer Res 67: 7850-7855. (Pubitemid 47281380)
    • (2007) Cancer Research , vol.67 , Issue.16 , pp. 7850-7855
    • Li, H.1    Zeng, Z.2    Fu, X.3    Zhang, X.4
  • 37
    • 59449089665 scopus 로고    scopus 로고
    • Improvement of gemcitabine-based therapy of pancreatic carcinoma by means of oncolytic parvovirus H-1PV
    • Angelova, AL, Aprahamian, M, Grekova, SP, Hajri, A, Leuchs, B, Giese, NA et al. (2009). Improvement of gemcitabine-based therapy of pancreatic carcinoma by means of oncolytic parvovirus H-1PV. Clin Cancer Res 15: 511-519.
    • (2009) Clin Cancer Res , vol.15 , pp. 511-519
    • Angelova, A.L.1    Aprahamian, M.2    Grekova, S.P.3    Hajri, A.4    Leuchs, B.5    Giese, N.A.6
  • 38
    • 77954541596 scopus 로고    scopus 로고
    • The viral tropism of two distinct oncolytic viruses, reovirus and myxoma virus, is modulated by cellular tumor suppressor gene status
    • Kim, M, Williamson, CT, Prudhomme, J, Bebb, DG, Riabowol, K, Lee, PW et al. (2010). The viral tropism of two distinct oncolytic viruses, reovirus and myxoma virus, is modulated by cellular tumor suppressor gene status. Oncogene 29: 3990-3996.
    • (2010) Oncogene , vol.29 , pp. 3990-3996
    • Kim, M.1    Williamson, C.T.2    Prudhomme, J.3    Bebb, D.G.4    Riabowol, K.5    Lee, P.W.6
  • 39
    • 33846504772 scopus 로고    scopus 로고
    • Oncolytic virotherapy synergism with signaling inhibitors: Rapamycin increases myxoma virus tropism for human tumor cells
    • DOI 10.1128/JVI.01408-06
    • Stanford, MM, Barrett, JW, Nazarian, SH, Werden, S and McFadden, G (2007). Oncolytic virotherapy synergism with signaling inhibitors: Rapamycin increases myxoma virus tropism for human tumor cells. J Virol 81: 1251-1260. (Pubitemid 46167846)
    • (2007) Journal of Virology , vol.81 , Issue.3 , pp. 1251-1260
    • Stanford, M.M.1    Barrett, J.W.2    Nazarian, S.H.3    Werden, S.4    McFadden, G.5
  • 40
    • 66149114469 scopus 로고    scopus 로고
    • Myxoma virus expressing interleukin-15 fails to cause lethal myxomatosis in European rabbits
    • Liu, J, Wennier, S, Reinhard, M, Roy, E, MacNeill, A and McFadden, G (2009). Myxoma virus expressing interleukin-15 fails to cause lethal myxomatosis in European rabbits. J Virol 83: 5933-5938.
    • (2009) J Virol , vol.83 , pp. 5933-5938
    • Liu, J.1    Wennier, S.2    Reinhard, M.3    Roy, E.4    MacNeill, A.5    McFadden, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.