Instrumented roll technology for the design space development of roller compaction process

International Journal of Pharmaceutics

Volumn 426, Issue 1-2, 2012, Pages 116-131

  Nesarikar, Vishwas V ^a   Vatsaraj, Nipa ^a   Patel, Chandrakant ^a   Early, William ^a   Pandey, Preetanshu ^a   Sprockel, Omar ^a   Gao, Zhihui ^a   Jerzewski, Robert ^a   Miller, Ronald ^b   Levin, Michael ^c  

^a BRISTOL MYERS SQUIBB   (United States)

^b Miller Pharmaceutical Technology   (United States)

^c Milev Pharmaceutical Technology Consulting   (United States)

Author keywords

Instrumented roll; Process design space; Ribbon density; Ribbon normal stress; Roll gap; Roller compaction; Vacuum de aeration

Indexed keywords

CROSCARMELLOSE SODIUM; LACTOSE; LUBRICATING AGENT; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; NANORIBBON; SILICON DIOXIDE;

AERATION; ARTICLE; COMPRESSION; CONTROLLED STUDY; DRUG FORMULATION; FORCE TRANSDUCER; INSTRUMENTED ROLL TECHNOLOGY; MECHANICAL STRESS; NANOBIOTECHNOLOGY; POROSITY; PREDICTION; PRESSURE; PRIORITY JOURNAL; SENSOR; VACUUM;

CARBOXYMETHYLCELLULOSE SODIUM; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; COLLOIDS; DRUG COMPOUNDING; EQUIPMENT DESIGN; EXCIPIENTS; FEASIBILITY STUDIES; FRICTION; LACTOSE; LUBRICANTS; MODELS, CHEMICAL; PHARMACEUTICAL PREPARATIONS; POROSITY; PRESSURE; SILICON DIOXIDE; STEARIC ACIDS; STRESS, MECHANICAL; TECHNOLOGY, PHARMACEUTICAL; TENSILE STRENGTH; TRANSDUCERS, PRESSURE;

EID: 84862820834     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.01.032     Document Type: Article

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