Quantification of nerve agent adducts with albumin in rat plasma using liquid chromatography-isotope dilution tandem mass spectrometry

Journal of Chromatography A

Volumn 1229, Issue , 2012, Pages 164-171

  Bao, Yi ^a   Liu, Qin ^a   Chen, Jia ^a   Lin, Ying ^a   Wu, Bidong ^a   Xie, Jianwei ^a  

^a BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

Author keywords

Biomarker; Isotope dilution; LC MS MS; Nerve agents; Quantification

Indexed keywords

DETECTION LIMITS; DOSE EFFECTS; HIGH SENSITIVITY; INTERNAL STANDARDS; ISOTOPE DILUTIONS; LC-MS/MS; NERVE AGENTS; PROTEIN PURIFICATION; QUANTIFICATION; RAT PLASMA; RECOVERY EFFICIENCY; RELATIVE STANDARD DEVIATIONS; SENSITIVE METHOD; SOLID-PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; TYROSINE RESIDUES;

AMINO ACIDS; BIOMARKERS; BODY FLUIDS; DEUTERIUM; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

DILUTION;

ALBUMIN; CHOLINESTERASE; METHYLPHOSPHONOTHIOIC ACID S (2 DIISOPROPYLAMINOETHYL) O ETHYL ESTER; SARIN; SOMAN;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CALIBRATION; CHEMICAL ANALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ISOTOPE DILUTION ASSAY; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; QUANTITATIVE ANALYSIS; RAT; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; VALIDATION STUDY;

ANIMALS; BIOLOGICAL MARKERS; BUTYRYLCHOLINESTERASE; CHROMATOGRAPHY, LIQUID; LIMIT OF DETECTION; MALE; ORGANOTHIOPHOSPHORUS COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SARIN; SERUM ALBUMIN; SOMAN; TANDEM MASS SPECTROMETRY; TYROSINE;

RATTUS;

EID: 84862819022     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2012.01.032     Document Type: Article

References (19)

1. Okumura T., Hisaoka T., Naito T., Isonuma H., Okumura S., Miura K., Maekawa H., Ishimatsu S., Takasu N., Suzuki K. Environ. Toxicol. Pharmacol. 2005, 19:447.
2. Okudera H. J. Clin. Neurosci. 2002, 9:17.
3. Tsuchihashi H., Katagi M., Nishikawa M., Tatsuno M. J. Anal. Toxicol. 1998, 22:383.
4. Black R.M., Noort D. Chemical Weapons Convention Chemicals Analysis 2005, 403. Wiley, Chichester. M. Mesilaakso (Ed.).
5. Riches J., Morton I., Read R.W., Black R.M. J. Chromatogr. B 2005, 816:251.
6. Noort D., Benschop H.P., Black R.M. Toxicol. Appl. Pharmacol. 2002, 184:116.
7. Ellman J.L., Courtney K.D., Andres V., Featherstone R.M. Biochem. Pharmacol. 1961, 7:88.
8. Ciner F.L., McCord C.E., Plunkett R.W., Martin M.F., Croley T.R. J. Chromatogr. B 2007, 846:42.
9. Elhanany E., Ordentlich A., Dgany O., Kaplan D., Segall Y., Barak R., Velan B., Shafferman A. Chem. Res. Toxicol. 2001, 14:912.
10. Renner J.A., Dabisch P.A., Evans R.A., McGuire J.M., Totura A.L., Jakubowski E.M., Thomson S.A. J. Anal. Toxicol. 2008, 32:92.
11. McGuire J.M., Taylor J.T., Byers C.E., Jakubowski E.M., Thomson S.A. J. Anal. Toxicol. 2008, 32:73.
12. Fidder A., Hulst A.G., Noort D., de Ruiter R., van der Schans M.J., Benschop H.P., Langenberg J.P. Chem. Res. Toxicol. 2002, 15:582.
13. Noort D., Fidder A., van der Schans M.J., Hulst A.G. Anal. Chem. 2006, 78:6640.
14. Williams N.H., Harrison J.M., Read R.W., Black R.M. Arch. Toxicol. 2007, 81:627.
15. Li B., Nachon F., Froment M.-T., Verdier L., Debouzy J.-C., Brasme B., Gillon E., Schopfer L.M., Lockridge O., Masson P. Chem. Res. Toxicol. 2008, 21:421.
16. Read R.W., Riches J.R., Stevens J.A., Stubbs S.J., Black R.M. Arch. Toxicol. 2010, 84:25.
17. Bryant P.J.R., Ford-Moore A.H., Perry B.J., Wardrop A.W.H., Watkins T.F. J. Chem. Soc. 1960, 1553.
18. Kitas E.A., Tregear J.W., Johns R.B. J. Org. Chem. 1990, 55:4181.
19. Nigg N.H., Knaak J.B. Rev. Environ. Contam. Toxicol. 2000, 163:29.