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Volumn 8, Issue , 2012, Pages

Association between Ghrelin gene (GHRL) polymorphisms and clinical response to atypical antipsychotic drugs in Han Chinese schizophrenia patients

Author keywords

Atypical antipsychotics; Body mass index (BMI); Ghrelin (GHRL); Polymorphrism; Schizophrenia; Therapeutic effects

Indexed keywords

ALANINE; ARIPIPRAZOLE; ATYPICAL ANTIPSYCHOTIC AGENT; CLOZAPINE; CYSTEINE; GHRELIN; GLYCINE; LEUCINE; METHIONINE; OLANZAPINE; QUETIAPINE; RISPERIDONE; ZIPRASIDONE; DNA; NEUROLEPTIC AGENT;

EID: 84862816913     PISSN: None     EISSN: 17449081     Source Type: Journal    
DOI: 10.1186/1744-9081-8-11     Document Type: Article
Times cited : (23)

References (40)
  • 1
    • 0033638576 scopus 로고    scopus 로고
    • Catching up on schizophrenia: natural history and neurobiology
    • 10.1016/S0896-6273(00)00111-2, 11144342
    • Lewis DA, Lieberman JA. Catching up on schizophrenia: natural history and neurobiology. Neuron 2000, 28(2):325-334. 10.1016/S0896-6273(00)00111-2, 11144342.
    • (2000) Neuron , vol.28 , Issue.2 , pp. 325-334
    • Lewis, D.A.1    Lieberman, J.A.2
  • 2
    • 0034324209 scopus 로고    scopus 로고
    • The epidemiology of the genetic liability for schizophrenia
    • Hallmayer J. The epidemiology of the genetic liability for schizophrenia. Aust N Z J Psychiatr 2000, 34(Suppl):47-55.
    • (2000) Aust N Z J Psychiatr , vol.34 , Issue.SUPPL , pp. 47-55
    • Hallmayer, J.1
  • 3
    • 0029131849 scopus 로고
    • Genetic basis of schizophrenia
    • 10.1016/S0140-6736(95)92285-7, 7658823
    • McGuffin P, Owen MJ, Farmer AE. Genetic basis of schizophrenia. Lancet 1995, 346(8976):678-682. 10.1016/S0140-6736(95)92285-7, 7658823.
    • (1995) Lancet , vol.346 , Issue.8976 , pp. 678-682
    • McGuffin, P.1    Owen, M.J.2    Farmer, A.E.3
  • 4
    • 34548336745 scopus 로고    scopus 로고
    • Dopamin genes and schizophrenia: case closed or evidence pending?
    • 10.1093/schbul/sbm076, 2559466,2559466, 17630406
    • Talkowski ME, Bamne M, Mansour H, Nimgaonkar VL. Dopamin genes and schizophrenia: case closed or evidence pending?. Schizophr Bull 2007, 33(5):1071-1081. 10.1093/schbul/sbm076, 2559466,2559466, 17630406.
    • (2007) Schizophr Bull , vol.33 , Issue.5 , pp. 1071-1081
    • Talkowski, M.E.1    Bamne, M.2    Mansour, H.3    Nimgaonkar, V.L.4
  • 5
    • 59649120666 scopus 로고    scopus 로고
    • Association of variants in DISC1 with psychosis-related traits in a large population cohort
    • 10.1001/archgenpsychiatry.2008.524, 2704396, 19188535
    • Tomppo L, Hennah W, Miettunen J, Järvelin MR, Veijola J, Ripatti S, et al. Association of variants in DISC1 with psychosis-related traits in a large population cohort. Arch Gen Psychiatry 2009, 66(2):134-141. 10.1001/archgenpsychiatry.2008.524, 2704396, 19188535.
    • (2009) Arch Gen Psychiatry , vol.66 , Issue.2 , pp. 134-141
    • Tomppo, L.1    Hennah, W.2    Miettunen, J.3    Järvelin, M.R.4    Veijola, J.5    Ripatti, S.6
  • 6
    • 43549120199 scopus 로고    scopus 로고
    • Explorative study on the expression of neuregulin-1 gene in peripheral blood of schizophrenia
    • 10.1016/j.neulet.2007.09.051, 18455303
    • Zhang HX, Zhao JP, Lv LX, Li WQ, Xu L, Ouyang X, et al. Explorative study on the expression of neuregulin-1 gene in peripheral blood of schizophrenia. Neurosci Lett 2008, 438(1):1-5. 10.1016/j.neulet.2007.09.051, 18455303.
    • (2008) Neurosci Lett , vol.438 , Issue.1 , pp. 1-5
    • Zhang, H.X.1    Zhao, J.P.2    Lv, L.X.3    Li, W.Q.4    Xu, L.5    Ouyang, X.6
  • 7
    • 54049091644 scopus 로고    scopus 로고
    • Schizophrenia, obesity, and antipsychotic medications: what can we do?
    • 10.3810/pgm.2008.07.1786, 18654065
    • Citrome L, Vreeland B. Schizophrenia, obesity, and antipsychotic medications: what can we do?. Postgrad Med 2008, 120(2):18-33. 10.3810/pgm.2008.07.1786, 18654065.
    • (2008) Postgrad Med , vol.120 , Issue.2 , pp. 18-33
    • Citrome, L.1    Vreeland, B.2
  • 8
    • 79960844421 scopus 로고    scopus 로고
    • Impaired glycolytic response in peripheral blood mononuclear cells of first-onset antipsychotic-naive schizophrenia patients
    • 10.1038/mp.2010.71, 20585325
    • Herberth M, Koethe D, Cheng TM, Krzyszton ND, Schoeffmann S, Guest PC, et al. Impaired glycolytic response in peripheral blood mononuclear cells of first-onset antipsychotic-naive schizophrenia patients. Mol Psychiatry 2011, 16(8):848-859. 10.1038/mp.2010.71, 20585325.
    • (2011) Mol Psychiatry , vol.16 , Issue.8 , pp. 848-859
    • Herberth, M.1    Koethe, D.2    Cheng, T.M.3    Krzyszton, N.D.4    Schoeffmann, S.5    Guest, P.C.6
  • 9
    • 77957923642 scopus 로고    scopus 로고
    • Head-to-head comparisons of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: a systematic review and meta-analysis
    • 10.1016/j.schres.2010.07.012, 2957510, 20692814
    • Rummel-Kluge C, Komossa K, Schwarz S, Hunger H, Schmid F, Lobos CA, et al. Head-to-head comparisons of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: a systematic review and meta-analysis. Schizophr Res 2010, 123(2-3):225-233. 10.1016/j.schres.2010.07.012, 2957510, 20692814.
    • (2010) Schizophr Res , vol.123 , Issue.2-3 , pp. 225-233
    • Rummel-Kluge, C.1    Komossa, K.2    Schwarz, S.3    Hunger, H.4    Schmid, F.5    Lobos, C.A.6
  • 10
    • 34447263548 scopus 로고    scopus 로고
    • Variations in the preproghrelin gene correlate with higher body mass index, fat mass, and body dissatisfaction in young Japanese women
    • Ando T, Ichimaru Y, Konjiki F, Shoji M, Komaki G. Variations in the preproghrelin gene correlate with higher body mass index, fat mass, and body dissatisfaction in young Japanese women. Am J Clin Nutr 2007, 86(1):25-32.
    • (2007) Am J Clin Nutr , vol.86 , Issue.1 , pp. 25-32
    • Ando, T.1    Ichimaru, Y.2    Konjiki, F.3    Shoji, M.4    Komaki, G.5
  • 11
    • 33750434312 scopus 로고    scopus 로고
    • Preproghrelin Leu72Met variant contributes to overweight in middle-aged men of a Japanese large cohort
    • Kuzuya M, Ando F, Iguchi A, Shimokata H. Preproghrelin Leu72Met variant contributes to overweight in middle-aged men of a Japanese large cohort. Int J Obes (Lond) 2006, 30(11):1609-1614.
    • (2006) Int J Obes (Lond) , vol.30 , Issue.11 , pp. 1609-1614
    • Kuzuya, M.1    Ando, F.2    Iguchi, A.3    Shimokata, H.4
  • 12
    • 33846212805 scopus 로고    scopus 로고
    • Association between ghrelin gene variations and blood pressure in subjects with impaired glucose tolerance
    • 10.1016/j.amjhyper.2006.02.017, 16942934
    • Mager U, Kolehmainen M, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, et al. Association between ghrelin gene variations and blood pressure in subjects with impaired glucose tolerance. Am J Hypertens 2006, 19(9):920-926. 10.1016/j.amjhyper.2006.02.017, 16942934.
    • (2006) Am J Hypertens , vol.19 , Issue.9 , pp. 920-926
    • Mager, U.1    Kolehmainen, M.2    Lindström, J.3    Eriksson, J.G.4    Valle, T.T.5    Hämäläinen, H.6
  • 13
    • 33751522297 scopus 로고    scopus 로고
    • Polymorphisms in the ghrelin gene are associated with serum high-density lipoprotein cholesterol level and not with type 2 diabetes mellitus in Koreans
    • 10.1210/jc.2005-2549, 16954159
    • Choi HJ, Cho YM, Moon MK, Choi HH, Shin HD, Jang HC, et al. Polymorphisms in the ghrelin gene are associated with serum high-density lipoprotein cholesterol level and not with type 2 diabetes mellitus in Koreans. J Clin Endocrinol Metab 2006, 91(11):4657-4663. 10.1210/jc.2005-2549, 16954159.
    • (2006) J Clin Endocrinol Metab , vol.91 , Issue.11 , pp. 4657-4663
    • Choi, H.J.1    Cho, Y.M.2    Moon, M.K.3    Choi, H.H.4    Shin, H.D.5    Jang, H.C.6
  • 14
    • 28744433690 scopus 로고    scopus 로고
    • Variants in the ghrelin gene are associated with metabolic syndrome in the Old Order Amish
    • 10.1210/jc.2005-0549, 16204371
    • Steinle NI, Pollin TI, O'Connell JR, Mitchell BD, Shuldiner AR. Variants in the ghrelin gene are associated with metabolic syndrome in the Old Order Amish. J Clin Endocrinol Metab 2005, 90(12):6672-6677. 10.1210/jc.2005-0549, 16204371.
    • (2005) J Clin Endocrinol Metab , vol.90 , Issue.12 , pp. 6672-6677
    • Steinle, N.I.1    Pollin, T.I.2    O'Connell, J.R.3    Mitchell, B.D.4    Shuldiner, A.R.5
  • 15
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • 10.1038/45230, 10604470
    • Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999, 402(6762):656-660. 10.1038/45230, 10604470.
    • (1999) Nature , vol.402 , Issue.6762 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 17
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • 10.1038/35038090, 11057670
    • Tschöp M, Smiley DL, Heiman ML. Ghrelin induces adiposity in rodents. Nature 2000, 407(6806):908-913. 10.1038/35038090, 11057670.
    • (2000) Nature , vol.407 , Issue.6806 , pp. 908-913
    • Tschöp, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 18
    • 0033711116 scopus 로고    scopus 로고
    • The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion
    • 10.1210/en.141.11.4325, 11089570
    • Wren AM, Small CJ, Ward HL, Murphy KG, Dakin CL, Taheri S, et al. The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology 2000, 141(11):4325-4328. 10.1210/en.141.11.4325, 11089570.
    • (2000) Endocrinology , vol.141 , Issue.11 , pp. 4325-4328
    • Wren, A.M.1    Small, C.J.2    Ward, H.L.3    Murphy, K.G.4    Dakin, C.L.5    Taheri, S.6
  • 19
    • 18244391222 scopus 로고    scopus 로고
    • Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion
    • 10.1210/jc.87.1.240, 11788653
    • Shiiya T, Nakazato M, Mizuta M, Date Y, Mondal MS, Tanaka M, et al. Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion. J Clin Endocrinol Metab 2002, 87(1):240-244. 10.1210/jc.87.1.240, 11788653.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.1 , pp. 240-244
    • Shiiya, T.1    Nakazato, M.2    Mizuta, M.3    Date, Y.4    Mondal, M.S.5    Tanaka, M.6
  • 20
    • 3142658638 scopus 로고    scopus 로고
    • Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity
    • 10.1073/pnas.0403465101, 478601, 15231997
    • Yildiz BO, Suchard MA, Wong ML, McCann SM, Licinio J. Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity. Proc Natl Acad Sci USA 2004, 101(28):10434-10439. 10.1073/pnas.0403465101, 478601, 15231997.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.28 , pp. 10434-10439
    • Yildiz, B.O.1    Suchard, M.A.2    Wong, M.L.3    McCann, S.M.4    Licinio, J.5
  • 22
    • 4444259546 scopus 로고    scopus 로고
    • Olanzapine increases plasma ghrelin level in patients with schizophrenia
    • 10.1016/j.psyneuen.2004.05.008, 15358448
    • Murashita M, Kusumi I, Inoue T, Takahashi Y, Hosoda H, Kangawa K, et al. Olanzapine increases plasma ghrelin level in patients with schizophrenia. Psychoneuroendocrinology 2005, 30:106-110. 10.1016/j.psyneuen.2004.05.008, 15358448.
    • (2005) Psychoneuroendocrinology , vol.30 , pp. 106-110
    • Murashita, M.1    Kusumi, I.2    Inoue, T.3    Takahashi, Y.4    Hosoda, H.5    Kangawa, K.6
  • 23
    • 33645214469 scopus 로고    scopus 로고
    • Early effects of olanzapine on serum levels of ghrelin, adiponectin and leptin in patients with schizophrenia
    • Hosojima H, Togo T, Odawara T, Hasegawa K, Miura S, Kato Y, et al. Early effects of olanzapine on serum levels of ghrelin, adiponectin and leptin in patients with schizophrenia. J Psychopharmacol 2006, 20:75-79.
    • (2006) J Psychopharmacol , vol.20 , pp. 75-79
    • Hosojima, H.1    Togo, T.2    Odawara, T.3    Hasegawa, K.4    Miura, S.5    Kato, Y.6
  • 24
  • 26
    • 68349132093 scopus 로고    scopus 로고
    • The role of ghrelin and ghrelin-receptor gene variants and promoter activity in type 2 diabetes
    • 10.1530/EJE-09-0122, 19460888
    • Garcia EA, King P, Sidhu K, Ohgusu H, Walley A, Lecoeur C, et al. The role of ghrelin and ghrelin-receptor gene variants and promoter activity in type 2 diabetes. Eur J Endocrinol 2009, 161(2):307-315. 10.1530/EJE-09-0122, 19460888.
    • (2009) Eur J Endocrinol , vol.161 , Issue.2 , pp. 307-315
    • Garcia, E.A.1    King, P.2    Sidhu, K.3    Ohgusu, H.4    Walley, A.5    Lecoeur, C.6
  • 27
    • 4344622156 scopus 로고    scopus 로고
    • Pharmacogenetics of antipsychotic-induced weight gain
    • Correll CU, Malhotra AK. Pharmacogenetics of antipsychotic-induced weight gain. Psychopharmacology (Berl) 2004, 174(4):477-489.
    • (2004) Psychopharmacology (Berl) , vol.174 , Issue.4 , pp. 477-489
    • Correll, C.U.1    Malhotra, A.K.2
  • 28
    • 0038804193 scopus 로고    scopus 로고
    • Ghrelin as a potential anti-obesity target
    • 10.2174/1381612033454748, 12769730
    • Horvath TL, Castañeda T, Tang-Christensen M, et al. Ghrelin as a potential anti-obesity target. Curr Pharm Des 2003, 9(17):1383-1395. 10.2174/1381612033454748, 12769730.
    • (2003) Curr Pharm Des , vol.9 , Issue.17 , pp. 1383-1395
    • Horvath, T.L.1    Castañeda, T.2    Tang-Christensen, M.3
  • 29
    • 84862828442 scopus 로고    scopus 로고
    • Online datebase center, sponsored by NARSAD and the Mental Health Research Association [DB/OL]
    • Online datebase center, sponsored by NARSAD and the Mental Health Research Association [DB/OL]. 2005, , http://www.schizophreniaforum.org/res/sczgene/default.asp
    • (2005)
  • 30
    • 79952752497 scopus 로고    scopus 로고
    • The association of ghrelin polymorphisms with coronary artery disease and ischemic chronic heart failure in an elderly Chinese population
    • 10.1016/j.clinbiochem.2010.12.013, 21195705
    • Zhang Q, Huang WD, Lv XY, Yang YM. The association of ghrelin polymorphisms with coronary artery disease and ischemic chronic heart failure in an elderly Chinese population. Clin Biochem 2011, 44(5-6):386-390. 10.1016/j.clinbiochem.2010.12.013, 21195705.
    • (2011) Clin Biochem , vol.44 , Issue.5-6 , pp. 386-390
    • Zhang, Q.1    Huang, W.D.2    Lv, X.Y.3    Yang, Y.M.4
  • 31
    • 37349112709 scopus 로고    scopus 로고
    • Variants within the ghrelin gene-association with HDL-cholesterol, but not with body mass index
    • Hubácek JA, Bohuslavová R, Skodová Z, Adámková V. Variants within the ghrelin gene-association with HDL-cholesterol, but not with body mass index. Folia Biol (Praha) 2007, 53(6):202-206.
    • (2007) Folia Biol (Praha) , vol.53 , Issue.6 , pp. 202-206
    • Hubácek, J.A.1    Bohuslavová, R.2    Skodová, Z.3    Adámková, V.4
  • 32
    • 33744781059 scopus 로고    scopus 로고
    • Association of the Leu72Met polymorphism of the ghrelin gene with the risk of type 2 diabetes in subjects with impaired glucose tolerance in the Finnish Diabetes Prevention Study
    • 10.1111/j.1464-5491.2006.01870.x, 16759313
    • Mager U, Lindi V, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, et al. Association of the Leu72Met polymorphism of the ghrelin gene with the risk of type 2 diabetes in subjects with impaired glucose tolerance in the Finnish Diabetes Prevention Study. Diabet Med 2006, 23(6):685-689. 10.1111/j.1464-5491.2006.01870.x, 16759313.
    • (2006) Diabet Med , vol.23 , Issue.6 , pp. 685-689
    • Mager, U.1    Lindi, V.2    Lindström, J.3    Eriksson, J.G.4    Valle, T.T.5    Hämäläinen, H.6
  • 33
    • 0004235298 scopus 로고
    • Diagnostic and Statistical Manual of Mental Disorders
    • Washington, DC: American Psychiatric Press, fourth, American Psychiatric Association
    • American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders. 1994, Washington, DC: American Psychiatric Press, fourth, American Psychiatric Association.
    • (1994)
  • 34
    • 0023858453 scopus 로고
    • Reliability and validity of the positive and negative syndrome scale for schizophrenics
    • 10.1016/0165-1781(88)90038-8, 3363019
    • Kay SR, Opler LA, Lindenmayer JP. Reliability and validity of the positive and negative syndrome scale for schizophrenics. Psychiatry Res 1988, 23(1):99-110. 10.1016/0165-1781(88)90038-8, 3363019.
    • (1988) Psychiatry Res , vol.23 , Issue.1 , pp. 99-110
    • Kay, S.R.1    Opler, L.A.2    Lindenmayer, J.P.3
  • 35
    • 84862792188 scopus 로고    scopus 로고
    • Relationship in dosage, serum concentration and clinical response of olanzap ine in schizophrenic patients
    • Zhang ML. Relationship in dosage, serum concentration and clinical response of olanzap ine in schizophrenic patients. Chin J Psychiatry 2003, 36(3):139.
    • (2003) Chin J Psychiatry , vol.36 , Issue.3 , pp. 139
    • Zhang, M.L.1
  • 36
    • 12244264435 scopus 로고    scopus 로고
    • Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits
    • 10.1093/bioinformatics/19.1.149, 12499305
    • Purcell S, Cherny SS, Sham PC. Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics 2003, 19(1):149-150. 10.1093/bioinformatics/19.1.149, 12499305.
    • (2003) Bioinformatics , vol.19 , Issue.1 , pp. 149-150
    • Purcell, S.1    Cherny, S.S.2    Sham, P.C.3
  • 37
    • 18944381751 scopus 로고    scopus 로고
    • SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci
    • 10.1038/sj.cr.7290272, 15740637
    • Shi YY, He L. SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci. Cell Res 2005, 15(2):97-98. 10.1038/sj.cr.7290272, 15740637.
    • (2005) Cell Res , vol.15 , Issue.2 , pp. 97-98
    • Shi, Y.Y.1    He, L.2
  • 38
    • 2642543937 scopus 로고    scopus 로고
    • Association study of -1727 A/T, -50 C/T and (CAA)n repeat GSK-3beta gene polymorphisms with schizophrenia
    • 10.1159/000077936, 15179015
    • Scassellati C, Bonvicini C, Perez J, Bocchio-Chiavetto L, Tura GB, Rossi G, et al. Association study of -1727 A/T, -50 C/T and (CAA)n repeat GSK-3beta gene polymorphisms with schizophrenia. Neuropsychobiology 2004, 50(1):16-20. 10.1159/000077936, 15179015.
    • (2004) Neuropsychobiology , vol.50 , Issue.1 , pp. 16-20
    • Scassellati, C.1    Bonvicini, C.2    Perez, J.3    Bocchio-Chiavetto, L.4    Tura, G.B.5    Rossi, G.6
  • 39
    • 52649105994 scopus 로고    scopus 로고
    • Multiple genetic factors in olanzapine-induced weight gain in schizophrenia patients: a cohort study
    • 10.4088/JCP.v69n0909, 19193342
    • Ujike H, Nomura A, Morita Y, Morio A, Okahisa Y, Kotaka T, et al. Multiple genetic factors in olanzapine-induced weight gain in schizophrenia patients: a cohort study. J Clin Psychiatry 2008, 69:1416-1422. 10.4088/JCP.v69n0909, 19193342.
    • (2008) J Clin Psychiatry , vol.69 , pp. 1416-1422
    • Ujike, H.1    Nomura, A.2    Morita, Y.3    Morio, A.4    Okahisa, Y.5    Kotaka, T.6
  • 40
    • 4344622156 scopus 로고    scopus 로고
    • Pharmacogenetics of antipsychotic-induced weight gain
    • Correll CU, Malhotra AK. Pharmacogenetics of antipsychotic-induced weight gain. Psychopharmacology 2004, 174(4):477-489.
    • (2004) Psychopharmacology , vol.174 , Issue.4 , pp. 477-489
    • Correll, C.U.1    Malhotra, A.K.2


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