Anti-inflammatory and anti-allergic effects of Agrimonia pilosa Ledeb extract on murine cell lines and OVA-induced airway inflammation

Journal of Ethnopharmacology

Volumn 140, Issue 2, 2012, Pages 213-221

  Kim, Jae Jin ^a,f   Jiang, Jun ^a   Shim, Do Wan ^a   Kwon, Sang Chul ^b   Kim, Tack Joong ^c   Ye, Sang Kyu ^d   Kim, Myong Ki ^e   Shin, Yong Kook ^e   Koppula, Sushruta ^a   Kang, Tae Bong ^a   Choi, Dong Kug ^a   Lee, Kwang Ho ^a  

^a Konkuk University   (South Korea)

^b Food Safety Support Organization   (South Korea)

^c Yonsei University Wonju   (South Korea)

^d Seoul National University   (South Korea)

^e Chungbuk Technopark   (South Korea)

^f International Vaccine Institute   (South Korea)

Author keywords

Agrimonia pilosa; AKT; Anti allergic; Inflammation; Macrophage; TRIF

Indexed keywords

AGRIMONIA PILOSA LEDEB EXTRACT; ANTIALLERGIC AGENT; IMMUNOGLOBULIN E; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; METHANOL; NITRIC OXIDE; OVALBUMIN; PLANT EXTRACT; PROSTAGLANDIN E2; PROTEIN KINASE B; PROTEIN KINASE SYK; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; BASOPHIL; CELL LINE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEGRANULATION; DRUG POTENCY; FEMALE; IMMUNOCOMPETENT CELL; IN VITRO STUDY; INFLAMMATION; LUNG LAVAGE; MACROPHAGE; MEDIATOR RELEASE; MOUSE; NONHUMAN; RESPIRATORY TRACT DISEASE; SIGNAL TRANSDUCTION;

AGRIMONIA; ANIMALS; ANTI-ALLERGIC AGENTS; ANTI-INFLAMMATORY AGENTS; ASTHMA; BASOPHILS; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE; CYTOKINES; DINITROPHENOLS; DISEASE MODELS, ANIMAL; FEMALE; IMMUNOGLOBULIN E; INFLAMMATION; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; LUNG; MACROPHAGE ACTIVATION; MICE; MICE, INBRED BALB C; OVALBUMIN; PHYTOTHERAPY; PLANT EXTRACTS; RATS; SIGNAL TRANSDUCTION;

AGRIMONIA PILOSA; MURINAE; RATTUS; ROSACEAE;

EID: 84862814239     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.12.035     Document Type: Article

References (40)

1. Bae, H., Kim, H.J., Shin, M., Lee, H., Yin, C.S., Ra, J., Kim, J., 2010. Inhibitory effect of Agrimoniae Herba on lipopolysaccharide-induced nitric oxide and proinflammatory cytokine production in BV2 microglial cells. Neurological Research 32, 53-57.
2. Berenbaum, F., 2000. Proinflammatory cytokines, prostaglandins, and the chondrocyte: mechanisms of intracellular activation. Joint Bone Spine 67, 561-564. (Pubitemid 32014796)
3. Carroll, K., Ray, K., Helm, B.A., Carey, E., 2001. Differential expression of Rab3 isoforms in high- and low-secreting mast cell lines. European Journal of Cell Biology 80, 295-302. (Pubitemid 32390147)
4. Church, M.K., Levi-Schaffer, F., 1997. The human mast cell. The Journal of Allergy and Clinical Immunology 99, 155-160. (Pubitemid 27091561)
5. Coker, R.K., Laurent, L.G., 1998. Pulmonary fibrosis: cytokines in the balance. European Respiratory Journal 11, 1218-1221. (Pubitemid 28298579)
6. Denburg, J.A., Inman, M.D., Sehmi, R., Uno, M., O'Byrne, P.M., 1998. Hemopoietic mechanisms in allergic airway inflammation. International Archives of Allergy and Immunology 117, 155-159. (Pubitemid 28526161)
7. Fujiwara, N., Kobayashi, K., 2005. Macrophages in inflammation. Current Drug Targets - Inflammtion and Allergy 4, 281-286.
8. Gilfillan, A.M., Tkaczyk, C., 2006. Integrated signalling pathways for mast-cell activation. Nature Reviews Immunology 6, 218-230. (Pubitemid 43290991)
9. Guha, M., O'Connell, M.A., Pawlinski, R., Hollis, A., McGovern, P., Yan, S.F., Stern, D., Mackman, N., 2001. Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor alpha expression by inducing Elk-1 phosphorylation and Egr-1 expression. Blood 98, 1429-1439.
10. Jung, C.H., Kim, J.H., Park, S.J., Kweon, D.H., Kim, S.H., Ko, S.G., 2010. Inhibitory effect of Agrimonia pilosa Ledeb. on inflammation by suppression of iNOS and ROS production. Immunological Investigations 39, 159-170.
11. Jung, M., Park, M., 2007. Acetylcholinesterase inhibition by flavonoids from Agrimonia pilosa. Molecules 12, 2130-2139.
12. Jung, C.H., Zhou, S., Ding, G.X., Kim, J.H., Hong, M.H., Shin, Y.C., Kim, G.J., Ko, S.G., 2006. Antihyperglycemic activity of herb extracts on streptozotocin-induced diabetic rats. Bioscience Biotechnology and Biochemistry 70, 2556-2559. (Pubitemid 44656429)
13. Kaminska, B., 2005. MAPK signaling pathways as molecular targets for antiinflammatory therapy-from molecular mechanisms to therapeutic benefits. Biochimica et Biophysica Acta 1754, 253-262. (Pubitemid 41797706)
14. Kato, H., Li, W., Koike, M., Wang, Y., Koike, K., 2010. Phenolic glycosides from Agrimonia pilosa. Phytochemistry 71, 1925-1929.
15. Kawai, T., Takeuchi, O., Fujita, T., Inoue, J., Muhlradt, P.F., Sato, S., Hoshino, K., Akira, S., 2001. Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes. Journal of Immunology 167, 5887-5894. (Pubitemid 33062783)
16. Koshiura, R., Miyamoto, K., Ikeya, Y., Taguchi, H., 1985. Antitumor activity of methanol extract from roots of Agrimonia pilosa Ledeb. Japanese Journal of Pharmacology 38, 9-16. (Pubitemid 15033274)
17. Kudva, P., Tabasum, S.T., Shekhawat, N.K., 2011. Effect of green tea catechin, a local drug delivery system as an adjunct to scaling and root planning in chronic periodontitis patients: a clinicomicrobiological study. Journal of Indian Society of Periodontology 15, 39-45.
18. Lawrence, T., Willoughby, D.A., Gilroy, D.W., 2002. Anti-inflammatory lipid mediators and insights into the resolution of inflammation. Nature Reviews Immunology 2, 787-795. (Pubitemid 37328718)
19. Lee, J., Bielory, L., 2010. Complementary and alternative interventions in atopic dermatitis. Immunology and Allergy Clinics of North America 30, 411-424.
20. Libby, P., Ridker, P.M., Maseri, A., 2002. Inflammation and atherosclerosis. Circulation 105, 1135-1143. (Pubitemid 34212626)
21. Li, Y., Ooi, L.S., Wang, H., But, P.P., Ooi, V.E., 2004. Antiviral activities of medicinal herbs traditionally used in southern mainland China. Phytotherapy Research, 718-722. (Pubitemid 39481690)
22. Mainardi, T., Kapoor, S., Bielory, L., 2009. Complementary and alternative medicine: herbs, phytochemicals and vitamins and their immunologic effects. Journal of Allergy and Clinical Immunology 123, 283-294.
23. Manzi, S., Wasko, M., 2000. Inflammation-mediated rheumatic diseases and atherosclerosis. Annals of the Rheumatic Diseases 59, 321-325. (Pubitemid 30316772)
24. Miyamoto, K., Kishi, N., Koshiura, R., 1987. Antitumor effect of agrimoniin, a tannin of Agrimonia pilosa Ledeb., on transplantable rodent tumors. Japanese Journal of Pharmacology 43, 187-195. (Pubitemid 17233848)
25. Pan, Y., Liu, H.X., Zhuang, Y.L., Ding, L.Q., Chen, L.X., Qiu, F., 2008. Studies on isolation and identification of flavonoids in herbs of Agrimonia pilosa. Zhongguo Zhong Yao Za Zhi 33, 2925-2928.
26. Paul, A., Cuenda, A., Bryant, C.E., Murray, J., Chilvers, E.R., Cohen, P., Gould, G.W., Plevin, R., 1999. Involvement of mitogen-activated protein kinase homologues in the regulation of lipopolysaccharide-mediated induction of cyclo-oxygenase-2 but not nitric oxide synthase in RAW 264.7 macrophages. Cellular Signalling 11, 491-497. (Pubitemid 29234118)
27. Roh, S.S., Kim, S.H., Lee, Y.C., Seo, Y.B., 2008. Effects of radix adenophorae and cyclosporine A on an OVA-induced murine model of asthma by suppressing to T cells activity, eosinophilia, and bronchial hyperresponsiveness. Mediators of Inflammation 2008, 781425.
28. Samavati, L., Rastogi, R., Du, W., Hüttemannc, M., Fite, A., Franchi, L., 2009. STAT3 tyrosine phosphorylation is critical for interleukin 1 beta and interleukin-6 production in response to lipopolysaccharide and live bacteria. Molecular Immunology 46, 1867-1877.
29. Shin, W.J., Lee, K.H., Park, M.H., Seong, B.L., 2010. Broad-spectrum antiviral effect of Agrimonia pilosa extract on influenza viruses. Microbiology and Immunology 54, 11-19.
30. Taira, J., Nanbu, H., Ueda, K., 2009. Nitric oxide-scavenging compounds in Agrimonia pilosa Ledeb on LPS-induced RAW264.7 macrophages. Food Chemistry 115, 1221-1227.
31. Takeda, K., Akira, S., 2007. Toll-like receptors. Current Protocols in Immunology 14, Unit 14.12.
32. Tak, P.P., Firestein, G., 2001. NF-kappaB: a key role in inflammatory diseases. Journal of Clinical Investigation 107, 7-11. (Pubitemid 32047405)
33. Talhouk, R.S., Karam, C., Fostok, S., El-Jouni, W., Barbour, E.K., 2007. Antiinflammatory bioactivities in plant extracts. Journal of Medicinal Food 10, 1-10.
34. Toshchakov, T., Jones, B.W., Perera, P.Y., Thomas, K., Cody, M.J., Zhang, S., Williams, B.R., Major, J., Hamilton, T.A., Fenton, M.J., Vogel, S.N., 2002. TLR4, but not TLR2, mediates IFN-β-induced STAT1α/β-dependent gene expression in macrophages. Nature Immunology 3, 392-398. (Pubitemid 34308628)
35. Wagner, C., Fachinetto, R., Dalla Corte, C.L., Brito, V.B., Severo, D., de Oliveira Costa Dias, G., Morel, A.F., Nogueira, C.W., Rocha, J.B., 2006. Quercitrin, a glycoside form of quercetin, prevents lipid peroxidation in vitro. Brain Research 1107, 192-198. (Pubitemid 44205111)
36. Wang, J.X., Hou, L.F., Yang, Y., Tang, W., Li, Y., Zuo, J.P., 2009. SM905, an artemisinin derivative, inhibited NO and pro-inflammatory cytokine production by suppressing MAPK and NF-κB pathways in RAW 264.7 macrophages. Acta Pharmacologica Sinica 30, 1428-1435.
37. Xu, X., Qi, X., Wang, W., Chen, G., 2005. Separation and determination of flavonoids in Agrimonia pilosa Ledeb. by capillary electrophoresis with electrochemical detection. Journal of Separation Science 28, 647-652. (Pubitemid 40711988)
38. Yamaki, M., Kashihara, M., Ishiguro, K., Takagi, S., 1989. Antimicrobial Principles of Xian he cao (Agrimonia pilosa). Planta Medica 55, 169-170. (Pubitemid 19095285)
39. Zhang, G., Ghosh, S., 2000. Molecular mechanisms of NF-kappaB activation induced by bacterial lipopolysaccharide through Toll-like receptors. Journal of Endotoxin Research 6, 453-457. (Pubitemid 32409432)
40. Zhu, L., Tan, J., Wang, B., He, R., Liu, Y., Zheng, C., 2009. Antioxidant activities of aqueous extract from Agrimonia pilosa Ledeb and its fractions. Chemistry and Biodiversity 6, 1716-1726.