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Volumn 32, Issue 6, 2012, Pages 977-987

Beneficial effects of candesartan, an angiotensin-blocking agent, on compensated alcoholic liver fibrosis - A randomized open-label controlled study

Author keywords

Alcoholic liver disease; Angiotensin II; Hepatic fibrosis; Renin angiotensin system

Indexed keywords

CANDESARTAN; GELATINASE A; HYDROXYPROLINE; RAC1 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; URSODEOXYCHOLIC ACID;

EID: 84862813779     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2012.02774.x     Document Type: Article
Times cited : (59)

References (35)
  • 1
    • 0001520008 scopus 로고
    • Hepatic lipocytes: the principal collagen-producing cells of normal rat liver
    • Friedman SL, Roll FJ, Boyles J, et al. Hepatic lipocytes: the principal collagen-producing cells of normal rat liver. Proc Natl Acad Sci U S A 1985; 82: 8681-5.
    • (1985) Proc Natl Acad Sci U S A , vol.82 , pp. 8681-8685
    • Friedman, S.L.1    Roll, F.J.2    Boyles, J.3
  • 2
    • 2142748551 scopus 로고    scopus 로고
    • Inhibitory effect of angiotensin II receptor antagonist on the contraction and growth of hepatic stellate cells
    • Baik SK, Jo HS, Suk KT, et al. Inhibitory effect of angiotensin II receptor antagonist on the contraction and growth of hepatic stellate cells. Korean J Gastroenterol 2003; 42: 134-41.
    • (2003) Korean J Gastroenterol , vol.42 , pp. 134-141
    • Baik, S.K.1    Jo, H.S.2    Suk, K.T.3
  • 3
    • 56649106258 scopus 로고    scopus 로고
    • Angiotensin receptor blockers are superior to angiotensin-converting enzyme inhibitors in the suppression of hepatic fibrosis in a bile duct-ligated rat model
    • Kim MY, Baik SK, Park DH, et al. Angiotensin receptor blockers are superior to angiotensin-converting enzyme inhibitors in the suppression of hepatic fibrosis in a bile duct-ligated rat model. J Gastroenterol 2008; 43: 889-96.
    • (2008) J Gastroenterol , vol.43 , pp. 889-896
    • Kim, M.Y.1    Baik, S.K.2    Park, D.H.3
  • 4
    • 51049087318 scopus 로고    scopus 로고
    • Inhibitory effect of angiotensin blockade on hepatic fibrosis in common bile duct-ligated rats
    • Park DH, Baik SK, Choi YH, et al. Inhibitory effect of angiotensin blockade on hepatic fibrosis in common bile duct-ligated rats. Korean J Hepatol 2007; 13: 61-9.
    • (2007) Korean J Hepatol , vol.13 , pp. 61-69
    • Park, D.H.1    Baik, S.K.2    Choi, Y.H.3
  • 5
    • 31644451945 scopus 로고    scopus 로고
    • Effects of six months losartan administration on liver fibrosis in chronic hepatitis C patients: a pilot study
    • Sookoian S, Fernandez MA, Castano G. Effects of six months losartan administration on liver fibrosis in chronic hepatitis C patients: a pilot study. World J Gastroenterol 2005; 11: 7560-3.
    • (2005) World J Gastroenterol , vol.11 , pp. 7560-7563
    • Sookoian, S.1    Fernandez, M.A.2    Castano, G.3
  • 6
    • 64749115204 scopus 로고    scopus 로고
    • The effect of angiotensin-blocking agents on liver fibrosis in patients with hepatitis C
    • Corey KE, Shah N, Misdraji J, et al. The effect of angiotensin-blocking agents on liver fibrosis in patients with hepatitis C. Liver Int 2009; 29: 748-53.
    • (2009) Liver Int , vol.29 , pp. 748-753
    • Corey, K.E.1    Shah, N.2    Misdraji, J.3
  • 7
    • 34247633516 scopus 로고    scopus 로고
    • AT1 receptor antagonist Candesartan in selected cirrhotic patients: effect on portal pressure and liver fibrosis markers
    • Debernardi-Venon W, Martini S, Biasi F, et al. AT1 receptor antagonist Candesartan in selected cirrhotic patients: effect on portal pressure and liver fibrosis markers. J Hepatol 2007; 46: 1026-33.
    • (2007) J Hepatol , vol.46 , pp. 1026-1033
    • Debernardi-Venon, W.1    Martini, S.2    Biasi, F.3
  • 8
    • 18644369234 scopus 로고    scopus 로고
    • Effect of angiotensin receptor antagonist on liver fibrosis in early stages of chronic hepatitis C
    • Terui Y, Saito T, Watanabe H, et al. Effect of angiotensin receptor antagonist on liver fibrosis in early stages of chronic hepatitis C. Hepatology 2002; 36: 1022.
    • (2002) Hepatology , vol.36 , pp. 1022
    • Terui, Y.1    Saito, T.2    Watanabe, H.3
  • 9
    • 70350511929 scopus 로고    scopus 로고
    • Effect of an angiotensin-II type-1 receptor blocker, candesartan on hepatic fibrosis in chronic hepatitis C: a prospective study
    • Ueki M, Koda M, Shimizu T, et al. Effect of an angiotensin-II type-1 receptor blocker, candesartan on hepatic fibrosis in chronic hepatitis C: a prospective study. Hepatogastroenterology 2009; 56: 1100-4.
    • (2009) Hepatogastroenterology , vol.56 , pp. 1100-1104
    • Ueki, M.1    Koda, M.2    Shimizu, T.3
  • 10
    • 0036130415 scopus 로고    scopus 로고
    • Indication of liver transplantation in severe alcoholic liver cirrhosis: quantitative evaluation and optimal timing
    • Veldt BJ, Laine F, Guillygomarc'h A, et al. Indication of liver transplantation in severe alcoholic liver cirrhosis: quantitative evaluation and optimal timing. J Hepatol 2002; 36: 93-8.
    • (2002) J Hepatol , vol.36 , pp. 93-98
    • Veldt, B.J.1    Laine, F.2    Guillygomarc'h, A.3
  • 11
    • 28844490547 scopus 로고    scopus 로고
    • Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies
    • D'Amico G, Garcia-Tsao G, Pagliaro L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. J Hepatol 2006; 44: 217-31.
    • (2006) J Hepatol , vol.44 , pp. 217-231
    • D'Amico, G.1    Garcia-Tsao, G.2    Pagliaro, L.3
  • 12
    • 0035433365 scopus 로고    scopus 로고
    • Randomized comparison of long-term losartan versus propranolol in lowering portal pressure in cirrhosis
    • Gonzalez-Abraldes J, Albillos A, Banares R, et al. Randomized comparison of long-term losartan versus propranolol in lowering portal pressure in cirrhosis. Gastroenterology 2001; 121: 382-8.
    • (2001) Gastroenterology , vol.121 , pp. 382-388
    • Gonzalez-Abraldes, J.1    Albillos, A.2    Banares, R.3
  • 13
    • 0032988091 scopus 로고    scopus 로고
    • Effect of losartan, an angiotensin II receptor antagonist, on portal pressure in cirrhosis
    • Schneider AW, Kalk JF, Klein CP. Effect of losartan, an angiotensin II receptor antagonist, on portal pressure in cirrhosis. Hepatology 1999; 29: 334-9.
    • (1999) Hepatology , vol.29 , pp. 334-339
    • Schneider, A.W.1    Kalk, J.F.2    Klein, C.P.3
  • 14
    • 51749097517 scopus 로고    scopus 로고
    • Influence of liver biopsy on abstinence in alcohol-dependent patients
    • Trabut JB, Plat A, Thepot V, et al. Influence of liver biopsy on abstinence in alcohol-dependent patients. Alcohol Alcohol 2008; 43: 559-63.
    • (2008) Alcohol Alcohol , vol.43 , pp. 559-563
    • Trabut, J.B.1    Plat, A.2    Thepot, V.3
  • 15
    • 80054749411 scopus 로고    scopus 로고
    • Histological subclassification of cirrhosis using Laennec fibrosis scoring system correlates with clinical stage and grade of portal hypertension
    • Kim MY, Cho MY, Baik SK, et al. Histological subclassification of cirrhosis using Laennec fibrosis scoring system correlates with clinical stage and grade of portal hypertension. J Hepatol 2011; 55: 1004-9.
    • (2011) J Hepatol , vol.55 , pp. 1004-1009
    • Kim, M.Y.1    Cho, M.Y.2    Baik, S.K.3
  • 16
    • 4244195920 scopus 로고    scopus 로고
    • The Laennec grading system for assessment of hepatic fibrosis: validation by correlation with wedged hepatic vein pressure and clinical features
    • Kutami R, Girgrah N, Wanless IR, et al. The Laennec grading system for assessment of hepatic fibrosis: validation by correlation with wedged hepatic vein pressure and clinical features. Hepatology 2000; 32: 407A.
    • (2000) Hepatology , vol.32
    • Kutami, R.1    Girgrah, N.2    Wanless, I.R.3
  • 17
    • 0036721452 scopus 로고    scopus 로고
    • Lack of progressive hepatic fibrosis during long-term therapy with deferiprone in subjects with transfusion-dependent beta-thalassemia
    • Wanless IR, Sweeney G, Dhillon AP, et al. Lack of progressive hepatic fibrosis during long-term therapy with deferiprone in subjects with transfusion-dependent beta-thalassemia. Blood 2002; 100: 1566-9.
    • (2002) Blood , vol.100 , pp. 1566-1569
    • Wanless, I.R.1    Sweeney, G.2    Dhillon, A.P.3
  • 18
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • Kleinder DE, Brunt EM, Van Natta M, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005; 41: 1313-21.
    • (2005) Hepatology , vol.41 , pp. 1313-1321
    • Kleinder, D.E.1    Brunt, E.M.2    Van Natta, M.3
  • 19
    • 9144224755 scopus 로고    scopus 로고
    • Captopril reduces portal pressure effectively in portal hypertensive patients with low portal venous velocity
    • Baik SK, Park DH, Kim MY, et al. Captopril reduces portal pressure effectively in portal hypertensive patients with low portal venous velocity. J Gastroenterol 2003; 38: 1150-4.
    • (2003) J Gastroenterol , vol.38 , pp. 1150-1154
    • Baik, S.K.1    Park, D.H.2    Kim, M.Y.3
  • 20
    • 4644349694 scopus 로고    scopus 로고
    • Characteristics of potassium and calcium currents of hepatic stellate cells (ito) in rat
    • Lee KI, Kong ID, Baik SK, et al. Characteristics of potassium and calcium currents of hepatic stellate cells (ito) in rat. Yonsei Med J 2004; 45: 649-60.
    • (2004) Yonsei Med J , vol.45 , pp. 649-660
    • Lee, K.I.1    Kong, I.D.2    Baik, S.K.3
  • 21
    • 0031951945 scopus 로고    scopus 로고
    • Angiotensin II stimulates the production of NO and peroxynitrite in endothelial cells
    • Pueyo ME, Arnal JF, Rami J, et al. Angiotensin II stimulates the production of NO and peroxynitrite in endothelial cells. Am J Physiol 1998; 274: C214-20.
    • (1998) Am J Physiol , vol.274
    • Pueyo, M.E.1    Arnal, J.F.2    Rami, J.3
  • 22
    • 0031041547 scopus 로고    scopus 로고
    • Role of superoxide in angiotensin II-induced but not catecholamine-induced hypertension
    • Laursen JB, Rajagopalan S, Galis Z, et al. Role of superoxide in angiotensin II-induced but not catecholamine-induced hypertension. Circulation 1997; 95: 588-93.
    • (1997) Circulation , vol.95 , pp. 588-593
    • Laursen, J.B.1    Rajagopalan, S.2    Galis, Z.3
  • 23
    • 0035960677 scopus 로고    scopus 로고
    • Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease
    • Heitzer T, Schlinzig T, Krohn K, et al. Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation 2001; 104: 2673-8.
    • (2001) Circulation , vol.104 , pp. 2673-2678
    • Heitzer, T.1    Schlinzig, T.2    Krohn, K.3
  • 24
    • 0031015288 scopus 로고    scopus 로고
    • p22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats
    • Fukui T, Ishizaka N, Rajagopalan S, et al. p22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats. Circ Res 1997; 80: 45-51.
    • (1997) Circ Res , vol.80 , pp. 45-51
    • Fukui, T.1    Ishizaka, N.2    Rajagopalan, S.3
  • 25
    • 0031757056 scopus 로고    scopus 로고
    • Candesartan cilexetil. A review of its use in essential hypertension
    • McClellan KJ, Goa KL. Candesartan cilexetil. A review of its use in essential hypertension. Drugs 1998; 56: 847-69.
    • (1998) Drugs , vol.56 , pp. 847-869
    • McClellan, K.J.1    Goa, K.L.2
  • 26
    • 0031566881 scopus 로고    scopus 로고
    • Candesartan (CV-11974) dissociates slowly from the angiotensin AT1 receptor
    • Ojima M, Inada Y, Shibouta Y, et al. Candesartan (CV-11974) dissociates slowly from the angiotensin AT1 receptor. Eur J Pharmacol 1997; 319: 137-46.
    • (1997) Eur J Pharmacol , vol.319 , pp. 137-146
    • Ojima, M.1    Inada, Y.2    Shibouta, Y.3
  • 27
    • 0034685168 scopus 로고    scopus 로고
    • Angiotensin II receptor antagonists
    • Burnier M, Brunner HR. Angiotensin II receptor antagonists. Lancet 2000; 355: 637-45.
    • (2000) Lancet , vol.355 , pp. 637-645
    • Burnier, M.1    Brunner, H.R.2
  • 28
    • 0346057802 scopus 로고    scopus 로고
    • Reduction of bleomycin induced lung fibrosis by candesartan cilexetil, an angiotensin II type 1 receptor antagonist
    • Otsuka M, Takahashi H, Shiratori M, et al. Reduction of bleomycin induced lung fibrosis by candesartan cilexetil, an angiotensin II type 1 receptor antagonist. Thorax 2004; 59: 31-8.
    • (2004) Thorax , vol.59 , pp. 31-38
    • Otsuka, M.1    Takahashi, H.2    Shiratori, M.3
  • 29
    • 0031458429 scopus 로고    scopus 로고
    • Involvement of angiotensin II in cardiovascular and renal injury: effects of an AT1-receptor antagonist on gene expression and the cellular phenotype
    • Suppl.
    • Kim S, Iwao H. Involvement of angiotensin II in cardiovascular and renal injury: effects of an AT1-receptor antagonist on gene expression and the cellular phenotype. J Hypertens 1997;15: S3-7, Suppl.
    • (1997) J Hypertens , vol.15
    • Kim, S.1    Iwao, H.2
  • 30
    • 77955699301 scopus 로고    scopus 로고
    • High-dose ursodeoxycholic acid therapy for nonalcoholic steatohepatitis: a double-blind, randomized, placebo-controlled trial
    • Leuschner UF, Lindenthal B, Herrmann G, et al. High-dose ursodeoxycholic acid therapy for nonalcoholic steatohepatitis: a double-blind, randomized, placebo-controlled trial. Hepatology 2010; 52: 472-9.
    • (2010) Hepatology , vol.52 , pp. 472-479
    • Leuschner, U.F.1    Lindenthal, B.2    Herrmann, G.3
  • 31
    • 1542515099 scopus 로고    scopus 로고
    • Ursodeoxycholic acid for treatment of nonalcoholic steatohepatitis: results of a randomized trial
    • Lindor KD, Kowdley KV, Heathcote EJ, et al. Ursodeoxycholic acid for treatment of nonalcoholic steatohepatitis: results of a randomized trial. Hepatology 2004; 39: 770-8.
    • (2004) Hepatology , vol.39 , pp. 770-778
    • Lindor, K.D.1    Kowdley, K.V.2    Heathcote, E.J.3
  • 32
    • 0030852495 scopus 로고    scopus 로고
    • Combined analysis of randomized controlled trials of ursodeoxycholic acid in primary biliary cirrhosis
    • Poupon RE, Lindor KD, Cauch-Dudek K, et al. Combined analysis of randomized controlled trials of ursodeoxycholic acid in primary biliary cirrhosis. Gastroenterology 1997; 113: 884-90.
    • (1997) Gastroenterology , vol.113 , pp. 884-890
    • Poupon, R.E.1    Lindor, K.D.2    Cauch-Dudek, K.3
  • 33
    • 0038170271 scopus 로고    scopus 로고
    • Combined analysis of the effect of treatment with ursodeoxycholic acid on histologic progression in primary biliary cirrhosis
    • Poupon RE, Lindor KD, Pares A, et al. Combined analysis of the effect of treatment with ursodeoxycholic acid on histologic progression in primary biliary cirrhosis. J Hepatol 2003; 39: 12-6.
    • (2003) J Hepatol , vol.39 , pp. 12-16
    • Poupon, R.E.1    Lindor, K.D.2    Pares, A.3
  • 34
    • 84862832888 scopus 로고    scopus 로고
    • The diagnosis and treatment of primary biliary cirrhosis
    • Kim KA, Jeong SH. The diagnosis and treatment of primary biliary cirrhosis. Korean J Hepatol 2011; 17: 173-9.
    • (2011) Korean J Hepatol , vol.17 , pp. 173-179
    • Kim, K.A.1    Jeong, S.H.2
  • 35
    • 77955493804 scopus 로고    scopus 로고
    • Clinical features and prognosis of primary biliary cirrhosis in Korea
    • Kim KA, Jeong SH, Lee JI, et al. Clinical features and prognosis of primary biliary cirrhosis in Korea. Korean J Hepatol 2011; 16: 139-46.
    • (2011) Korean J Hepatol , vol.16 , pp. 139-146
    • Kim, K.A.1    Jeong, S.H.2    Lee, J.I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.