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Volumn 26, Issue 5, 2012, Pages 714-716

The impact of aging on the brain - Risk, resilience and repair

Author keywords

Immunology; Neuroprotection

Indexed keywords

CD200 ANTIGEN; CYTOKINE;

EID: 84862810545     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2012.02.005     Document Type: Note
Times cited : (3)

References (35)
  • 1
    • 14744281718 scopus 로고    scopus 로고
    • Long-term cytomegalovirus infection leads to significant changes in the composition of the CD8+ T-cell repertoire, which may be the basis for an imbalance in the cytokine production profile in elderly persons
    • Almanzar G., Schwaiger S., Jenewein B., Keller M., Herndler-Brandstetter D., Wurzner R., Schonitzer D., Grubeck-Loebenstein B. Long-term cytomegalovirus infection leads to significant changes in the composition of the CD8+ T-cell repertoire, which may be the basis for an imbalance in the cytokine production profile in elderly persons. J. Virol. 2005, 79:3675-3683.
    • (2005) J. Virol. , vol.79 , pp. 3675-3683
    • Almanzar, G.1    Schwaiger, S.2    Jenewein, B.3    Keller, M.4    Herndler-Brandstetter, D.5    Wurzner, R.6    Schonitzer, D.7    Grubeck-Loebenstein, B.8
  • 5
    • 38649119160 scopus 로고    scopus 로고
    • Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system
    • Chen J., Buchanan J.B., Sparkman N.L., Godbout J.P., Freund G.G., Johnson R.W. Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system. Brain Behav. Immun. 2008, 22:301-311.
    • (2008) Brain Behav. Immun. , vol.22 , pp. 301-311
    • Chen, J.1    Buchanan, J.B.2    Sparkman, N.L.3    Godbout, J.P.4    Freund, G.G.5    Johnson, R.W.6
  • 6
    • 0036293153 scopus 로고    scopus 로고
    • Cognitive impairment in elderly ED patients: need for multidimensional assessment for better management after discharge
    • Chiovenda P., Vincentelli G.M., Alegiani F. Cognitive impairment in elderly ED patients: need for multidimensional assessment for better management after discharge. Am. J. Emerg. Med. 2002, 20:332-335.
    • (2002) Am. J. Emerg. Med. , vol.20 , pp. 332-335
    • Chiovenda, P.1    Vincentelli, G.M.2    Alegiani, F.3
  • 7
    • 70449526190 scopus 로고    scopus 로고
    • Heterogeneity of microglial activation in the innate immune response in the brain
    • Colton C.A. Heterogeneity of microglial activation in the innate immune response in the brain. J. Neuroimmune. Pharmacol. 2009, 4:399-418.
    • (2009) J. Neuroimmune. Pharmacol. , vol.4 , pp. 399-418
    • Colton, C.A.1
  • 9
    • 37249094173 scopus 로고    scopus 로고
    • From inflammation to sickness and depression: when the immune system subjugates the brain
    • Dantzer R., O'Connor J.C., Freund G.G., Johnson R.W., Kelley K.W. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat. Rev. Neurosci. 2008, 9:46-56.
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 46-56
    • Dantzer, R.1    O'Connor, J.C.2    Freund, G.G.3    Johnson, R.W.4    Kelley, K.W.5
  • 12
    • 80052078622 scopus 로고    scopus 로고
    • The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease
    • Gleeson M., Bishop N.C., Stensel D.J., Lindley M.R., Mastana S.S., Nimmo M.A. The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease. Nat. Rev. Immunol. 2011, 11:607-615.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 607-615
    • Gleeson, M.1    Bishop, N.C.2    Stensel, D.J.3    Lindley, M.R.4    Mastana, S.S.5    Nimmo, M.A.6
  • 13
    • 23444443814 scopus 로고    scopus 로고
    • Exaggerated neuroinflammation and sickness behavior in aged mice following activation of the peripheral innate immune system
    • Godbout J.P., Chen J., Abraham J., Richwine A.F., Berg B.M., Kelley K.W., Johnson R.W. Exaggerated neuroinflammation and sickness behavior in aged mice following activation of the peripheral innate immune system. Faseb J. 2005, 19:1329-1331.
    • (2005) Faseb J. , vol.19 , pp. 1329-1331
    • Godbout, J.P.1    Chen, J.2    Abraham, J.3    Richwine, A.F.4    Berg, B.M.5    Kelley, K.W.6    Johnson, R.W.7
  • 15
    • 84861987890 scopus 로고    scopus 로고
    • Age related changes in microglial phenotype vary between CNS regions: grey versus white matter differences
    • in press
    • Hart, A.D., Wyttenbach, A., Hugh Perry, V., Teeling, J.L., in press. Age related changes in microglial phenotype vary between CNS regions: grey versus white matter differences. Brain Behav. Immun.
    • Brain Behav. Immun.
    • Hart, A.D.1    Wyttenbach, A.2    Hugh Perry, V.3    Teeling, J.L.4
  • 17
    • 84855164955 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids and cognition throughout the lifespan: a review
    • Karr J.E., Alexander J.E., Winningham R.G. Omega-3 polyunsaturated fatty acids and cognition throughout the lifespan: a review. Nutr. Neurosci. 2011, 14:216-225.
    • (2011) Nutr. Neurosci. , vol.14 , pp. 216-225
    • Karr, J.E.1    Alexander, J.E.2    Winningham, R.G.3
  • 21
    • 34547680192 scopus 로고    scopus 로고
    • CD200 ligand receptor interaction modulates microglial activation in vivo and in vitro: a role for IL-4
    • Lyons A., Downer E.J., Crotty S., Nolan Y.M., Mills K.H., Lynch M.A. CD200 ligand receptor interaction modulates microglial activation in vivo and in vitro: a role for IL-4. J. Neurosci. 2007, 27:8309-8313.
    • (2007) J. Neurosci. , vol.27 , pp. 8309-8313
    • Lyons, A.1    Downer, E.J.2    Crotty, S.3    Nolan, Y.M.4    Mills, K.H.5    Lynch, M.A.6
  • 22
    • 68149179573 scopus 로고    scopus 로고
    • Immunosenescence. what does it mean to health outcomes in older adults?
    • McElhaney J.E., Effros R.B. Immunosenescence. what does it mean to health outcomes in older adults?. Curr. Opin. Immunol. 2009, 21:418-424.
    • (2009) Curr. Opin. Immunol. , vol.21 , pp. 418-424
    • McElhaney, J.E.1    Effros, R.B.2
  • 24
    • 81355132325 scopus 로고    scopus 로고
    • Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function
    • Njie E.G., Boelen E., Stassen F.R., Steinbusch H.W., Borchelt D.R., Streit W.J. Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function. Neurobiol. Aging 2012, 33(195):e191-112.
    • (2012) Neurobiol. Aging , vol.33 , Issue.195
    • Njie, E.G.1    Boelen, E.2    Stassen, F.R.3    Steinbusch, H.W.4    Borchelt, D.R.5    Streit, W.J.6
  • 27
    • 0036604275 scopus 로고    scopus 로고
    • Lack of antibody production following immunization in old age: association with CD8(+)CD28(-) T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines
    • Saurwein-Teissl M., Lung T.L., Marx F., Gschosser C., Asch E., Blasko I., Parson W., Bock G., Schonitzer D., Trannoy E., Grubeck-Loebenstein B. Lack of antibody production following immunization in old age: association with CD8(+)CD28(-) T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines. J. Immunol. 2002, 168:5893-5899.
    • (2002) J. Immunol. , vol.168 , pp. 5893-5899
    • Saurwein-Teissl, M.1    Lung, T.L.2    Marx, F.3    Gschosser, C.4    Asch, E.5    Blasko, I.6    Parson, W.7    Bock, G.8    Schonitzer, D.9    Trannoy, E.10    Grubeck-Loebenstein, B.11
  • 29
    • 44649124786 scopus 로고    scopus 로고
    • Association of Alzheimer's disease and Chlamydophila pneumoniae
    • Stallings T.L. Association of Alzheimer's disease and Chlamydophila pneumoniae. J. Infect. 2008, 56:423-431.
    • (2008) J. Infect. , vol.56 , pp. 423-431
    • Stallings, T.L.1
  • 30
    • 71749111987 scopus 로고    scopus 로고
    • Aging promotes neutrophil-induced mortality by augmenting IL-17 production during viral infection
    • Stout-Delgado H.W., Du W., Shirali A.C., Booth C.J., Goldstein D.R. Aging promotes neutrophil-induced mortality by augmenting IL-17 production during viral infection. Cell Host Microbe 2009, 6:446-456.
    • (2009) Cell Host Microbe , vol.6 , pp. 446-456
    • Stout-Delgado, H.W.1    Du, W.2    Shirali, A.C.3    Booth, C.J.4    Goldstein, D.R.5
  • 31
    • 33749553972 scopus 로고    scopus 로고
    • Multiple sclerosis: an infectious syndrome involving Chlamydophila pneumoniae
    • Stratton C.W., Wheldon D.B. Multiple sclerosis: an infectious syndrome involving Chlamydophila pneumoniae. Trends Microbiol. 2006, 14:474-479.
    • (2006) Trends Microbiol. , vol.14 , pp. 474-479
    • Stratton, C.W.1    Wheldon, D.B.2
  • 32
    • 0029396261 scopus 로고
    • The brain's immune system
    • Streit W.J., Kincaid-Colton C.A. The brain's immune system. Sci. Am. 1995, 273(54-55):58-61.
    • (1995) Sci. Am. , vol.273 , Issue.54-55 , pp. 58-61
    • Streit, W.J.1    Kincaid-Colton, C.A.2
  • 33
    • 73949091048 scopus 로고    scopus 로고
    • Impaired immune responses in the lungs of aged mice following influenza infection
    • Toapanta F.R., Ross T.M. Impaired immune responses in the lungs of aged mice following influenza infection. Respir. Res. 2009, 10:112.
    • (2009) Respir. Res. , vol.10 , pp. 112
    • Toapanta, F.R.1    Ross, T.M.2
  • 35
    • 0029799987 scopus 로고    scopus 로고
    • Acute cognitive impairment in elderly ED patients: etiologies and outcomes
    • Wofford J.L., Loehr L.R., Schwartz E. Acute cognitive impairment in elderly ED patients: etiologies and outcomes. Am. J. Emerg. Med. 1996, 14:649-653.
    • (1996) Am. J. Emerg. Med. , vol.14 , pp. 649-653
    • Wofford, J.L.1    Loehr, L.R.2    Schwartz, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.