Reinforcement of electrospun membranes using nanoscale Al 2O 3 whiskers for improved tissue scaffolds

Journal of Biomedical Materials Research - Part A

Volumn 100 A, Issue 4, 2012, Pages 903-910

  Dong, Zexuan ^a   Wu, Yiquan ^a,b   Wang, Qin ^c   Xie, Chao ^d   Ren, Yanfang ^c   Clark, Robert L ^a  

^a University of Rochester   (United States)

^b Alfred University   (United States)

^c UNIVERSITY OF ROCHESTER   (United States)

^d UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Al 2O 3 whisker; electrospinning; poly( caprolactone); reinforcement; tissue scaffolds

Indexed keywords

BIOCOMPATIBLE MATERIALS; CAPROLACTONE; CELL MORPHOLOGY; CELLULAR ADHESION; DENTAL APPLICATIONS; ELECTROSPUN MEMBRANES; NANOSCALE AL; POROUS MORPHOLOGY; TISSUE ENGINEERING APPLICATIONS; TISSUE GROWTH; TISSUE SCAFFOLDS; WELL-ALIGNED; WELL-DISPERSED; WHISKER REINFORCEMENT; XRD , TEM;

ADHESION; ALUMINUM; BIOCOMPATIBILITY; BIOMECHANICS; ELASTIC MODULI; ELECTROSPINNING; MORPHOLOGY; REINFORCEMENT; TENSILE TESTING; TISSUE;

SCAFFOLDS (BIOLOGY);

ALUMINUM OXIDE; POLYCAPROLACTONE; TISSUE SCAFFOLD;

ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; ELECTROSPINNING; NONHUMAN; SCANNING ELECTRON MICROSCOPY; TISSUE ENGINEERING; TRANSMISSION ELECTRON MICROSCOPY; VIBRISSA; X RAY DIFFRACTION;

ALUMINUM OXIDE; BIOCOMPATIBLE MATERIALS; MEMBRANES, ARTIFICIAL; MICROSCOPY, ELECTRON, SCANNING; TENSILE STRENGTH; X-RAY DIFFRACTION;

EID: 84862809159     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.34027     Document Type: Article

References (42)

1. Shea LD, Wang D, Franceschi RT, Mooney DJ,. Engineered bone development from a pre-osteoblast cell line on three-dimensional scaffolds. Tissue Eng 2000; 6: 605-617.
2. Murugan R, Ramakrishna S,. Nano-featured scaffolds for tissue engineering: A review of spinning methodologies. Tissue Eng 2006; 12: 435-447.
3. Jayaraman K, Kotaki M, Zhang YZ, Mo XM, Ramakrishna S,. Recent advances in polymer nanofibers. J Nanosci Nanotechnol 2004; 4: 52-65.
4. Smith LA, Ma PX,. Nano-fibrous scaffolds for tissue engineering. Colloids Surf B 2004; 39: 125-131.
5. Ma ZW, Kotaki M, Inai R, Ramakrishna S,. Potential of nanofiber matrix as tissue-engineering scaffolds. Tissue Eng 2005; 11: 101-109.
6. Yoshimoto H, Shin YM, Terai H, Vacanti JP,. A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering. Biomaterials 2003; 24: 2077-2082.
7. Fujihara K, Kotaki M, Ramakrishna S,. Guided bone regeneration membrane made of polycaprolactone/calcium carbonate composite nano-fibers. Biomaterials 2005; 26: 4139-4147.
8. Zhang YZ, Ouyang HW, Lim CT, Ramakrishna S, Huang ZM,. Electrospinning of gelatin fibers and gelatin/PCL composite fibrous scaffolds. J Biomed Mater Res B Appl Biomater 2005; 72B: 156-165.
9. Li WJ, Danielson KG, Alexander PG, Tuan RS,. Biological response of chondrocytes cultured in three-dimensional nanofibrous poly (epsilon- caprolactone) scaffolds. J Biomed Mater Res A 2003; 67A: 1105-1114.
10. Shin M, Ishii O, Sueda T, Vacanti JP,. Contractile cardiac grafts using a novel nanofibrous mesh. Biomaterials 2004; 25: 3717-3723.
11. Jiang HL, Hu YQ, Li Y, Zhao PC, Zhu KJ, Chen WL,. A facile technique to prepare biodegradable coaxial electrospun nanofibers for controlled release of bioactive agents. J Control Release 2005; 108: 237-243.
12. Taylor G,. Disintegration of water drops in an electric field. Proc R Soc Lond A 1964; 280: 383-397.
13. Li D, Xia YN,. Electrospinning of nanofibers: Reinventing the wheel? Adv Mater 2004; 16: 1151-1170.
14. Causa F, Netti PA, Ambrosio L, Ciapetti G, Baldini N, Pagani S, Martini D, Giunti A,. Poly-epsilon-caprolactone/hydroxyapatite composites for bone regeneration: In vitro characterization and human osteoblast response. J Biomed Mater Res A 2006; 76A: 151-162.
15. Chen BQ, Sun K,. Mechanical and dynamic viscoelastic properties of hydroxyapatite reinforced poly(epsilon-caprolactone). Polym Test 2005; 24: 978-982.
16. Hao JY, Liu Y, Zhou SB, Li Z, Deng XM,. Investigation of nanocomposites based on semi-interpenetrating network of L-poly (epsilon-caprolactone)/net-poly (epsilon-caprolactone) and hydroxyapatite nanocrystals. Biomaterials 2003; 24: 1531-1539.
17. Mondrinos MJ, Dembzynski R, Lu L, Byrapogu VKC, Wootton DM, Lelkes PI, Zhou J,. Porogen-based solid freeform fabrication of polycaprolactone-calcium phosphate scaffolds for tissue engineering. Biomaterials 2006; 27: 4399-4408.
18. Kim HW, Knowles JC, Kim HE,. Effect of biphasic calcium phosphates on drug release and bioloigical and mechanical properties of poly(epsilon- caprolactone) composite membranes. J Biomed Mater Res A 2004; 70A: 467-479.
19. Lahiri D, Rouzaud F, Namin S, Keshri AK, Valdes JJ, Kos L, Tsoukias N, Agarwal A,. Carbon nanotube reinforced polylactide-caprolactone copolymer: Mechanical strengthening and interaction with human osteoblasts in vitro. ACS Appl Mater Interfaces 2009; 1: 2470-2476.
20. Chrissafis K, Antoniadis G, Paraskevopoulos KM, Vassiliou A, Bikiaris DN,. Comparative study of the effect of different nanoparticles on the mechanical properties and thermal degradation mechanism of in situ prepared poly(E-caprolactone) nanocomposites. Compos Sci Technol 2007; 67: 2165-2174.
21. Stevens MM, George JH,. Exploring and engineering the cell surface interface. Science 2005; 310: 1135-1138.
22. Miller DC, Thapa A, Haberstroh KM, Webster TJ,. Endothelial and vascular smooth muscle cell function on poly(lactic-co-glycolic acid) with nano-structured surface features. Biomaterials 2004; 25: 53-61.
23. Vonrecum AF, Vankooten TG,. The influence of micro-topography on cellular-response and the implications for silicone implants. J Biomater Sci Polymer Ed 1995; 7: 181-198.
24. Wan YQ, Wang Y, Liu ZM, Qu X, Han BX, Bei JZ, Wang SG,. Adhesion and proliferation of OCT-1 osteoblast-like cells on micro- and nano-scale topography structured pply(L-lactide). Biomaterials 2005; 26: 4453-4459.
25. Saeed K, Park SY, Lee HJ, Baek JB, Huh WS,. Preparation of electrospun nanofibers of carbon nanotube/polycaprolactone nanocomposite. Polymer 2006; 47: 8019-8025.
26. Zhang DH, Kandadai MA, Cech J, Roth S, Curran SA,. Poly(L-lactide) (PLLA)/multiwalled carbon nanotube (MWCNT) composite: Characterization and biocompatibility evaluation. J Phys Chem B 2006; 110: 12910-12915.
27. Venugopal JR, Low S, Choon AT, Kumar AB, Ramakrishna S,. Nanobioengineered electrospun composite nanofibers and osteoblasts for bone regeneration. Artif Organs 2008; 32: 388-397.
28. Gupta D, Venugopal J, Mitra S, Dev VRG, Ramakrishna S,. Nanostructured biocomposite substrates by electrospinning and electrospraying for the mineralization of osteoblasts. Biomaterials 2009; 30: 2085-2094.
29. George J, Sreekala MS, Thomas S,. A review on interface modification and characterization of natural fiber reinforced plastic composites. Polym Eng Sci 2001; 41: 1471-1485.
30. Fu SY, Lauke B,. The elastic modulus of misaligned short-fiber-reinforced polymers. Compos Sci Technol 1998; 58: 389-400.
31. Hench LL,. Bioceramics. J Am Ceram Soc 1998; 81: 1705-1728.
32. Rodriguez Lorenzo LM, Salinas AJ, ValletRegi M, Roman JS,. Composite biomaterials based on ceramic polymers 1. Reinforced systems based on Al2O3/PMMA/PLLA. J Biomed Mater Res 1996; 30: 515-522.
33. Takami Y, Nakazawa T, Makinouchi K, Glueck J, Nose Y,. Biocompatibility of alumina ceramic and polyethylene as materials for pivot bearings of a centrifugal blood pump. J Biomed Mater Res 1997; 36: 381-386.
34. Black J, Hastings G,. Handbook of Biomaterial Properties. London: Chapman and Hall; 1998. p 343-344.
35. Thomas V, Jagani S, Johnson K, Jose MV, Dean DR, Vohra YK, Nyairo E,. Electrospun bioactive nanocomposite scaffolds of polycaprolactone and nanohydroxyapatite for bone tissue engineering. J Nanosci Nanotechnol 2006; 6: 487-493.
36. Domingos M, Dinucci D, Cometa S, Alderighi M, Bartolo PJ, Chiellini F,. Polycaprolactone scaffolds fabricated via bioextrusion for tissue engineering applications. Int J Biomater 2009; 2009: 239643.
37. Guarino V, Causa F, Taddei P, di Foggia M, Ciapetti G, Martini D, Fagnano C, Baldini N, Ambrosio L,. Polylactic acid fibre-reinforced polycaprolactone scaffolds for bone tissue engineering. Biomaterials 2008; 29: 3662-3670.
38. Serrano MC, Pagani R, Vallet-Regi M, Pena J, Ramila A, Izquierdo I, Portoles MT,. In vitro biocompatibility assessment of poly(epsilon-caprolactone) films using L929 mouse fibroblasts. Biomaterials 2004; 25: 5603-5611.
39. Thapa A, Webster TJ, Haberstroh KM,. Polymers with nano-dimensional surface features enhance bladder smooth muscle cell adhesion. J Biomed Mater Res A 2003; 67A: 1374-1383.
40. Vance RJ, Miller DC, Thapa A, Haberstroh KM, Webster TJ,. Decreased fibroblast cell density on chemically degraded poly-lactic-co-glycolic acid, polyurethane, and polycaprolactone. Biomaterials 2004; 25: 2095-2103.
41. Azevedo MC, Reis RL, Claase BM, Grijpma DW, Feijen J,. Development and properties of polycaprolactone/hydroxyapatite composite biomaterials. J Mater Sci Mater Med 2003; 14: 103-107.
42. Brodnyan JG,. The concentration dependence of the Newtonian viscosity of prolate ellipsoids. Trans Soc Rheol 1959; 3: 61-68.