Design and synthesis of novel inhibitors of human kynurenine aminotransferase-I

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 4, 2012, Pages 1579-1581

  Akladios, Fady N ^a   Nadvi, Naveed A ^a,b   Park, Joohong ^b   Hanrahan, Jane R ^a   Kapoor, Vimal ^c   Gorrell, Mark D ^b   Church, W Bret ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Indole propionic acid; Kynurenic acid; Kynurenine; Kynurenine aminotransferase I; Phenyl hydrazones; Schizophrenia

Indexed keywords

AMINOTRANSFERASE INHIBITOR; INDOL 3 ACRYLIC ACID; INDOLEACETIC ACID; INDOLELACTIC ACID; INDOLEPROPIONIC ACID; INDOLEPYRUVIC ACID; KYNURENINE AMINOTRANSFERASE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ARTICLE; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAVIOLET RADIATION;

EID: 84862807159     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.12.138     Document Type: Article

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