A novel peptide to treat oral mucositis blocks endothelial and epithelial cell apoptosis

International Journal of Radiation Oncology Biology Physics

Volumn 83, Issue 3, 2012, Pages

  Wu, Xiaoyan ^a   Chen, Peili ^a   Sonis, Stephen T ^b,c   Lingen, Mark W ^a   Berger, Ann ^d   Toback, F Gary ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c Biomodels   (United States)

^d NephRx Corporation   (United States)

Author keywords

Apoptosis; Endothelial cells; Epithelial cells; Gastrokine 1; Oral mucositis

Indexed keywords

ANIMAL MODEL; ANNEXINS; ANTIAPOPTOTIC ACTIVITIES; CELL MONOLAYERS; CELL TYPES; CHEMORADIATION; CIS-PLATIN; CONVENTIONAL TREATMENTS; ENDOTHELIAL CELL LINE; EPITHELIAL CELLS; FRACTIONATED RADIATION; GASTROKINE 1; HEAD-AND-NECK CANCER; HIGH TEMPERATURE; INDUCED APOPTOSIS; KERATINOCYTES; MICROVASCULAR ENDOTHELIAL CELLS; MITOGENIC; MUCOSAL PROTEINS; ORAL MUCOSA; ORAL MUCOSITIS; PROPIDIUM IODIDE; PROTECTIVE EFFECTS; RADIATION-INDUCED; SINGLE-DOSE; THREE MODELS; TUMOR NECROSIS FACTORS;

AMINO ACIDS; CHEMICAL COMPOUNDS; DERMATOLOGY; DISEASES; DRUG PRODUCTS; ENDOTHELIAL CELLS; FLOW CYTOMETRY; GLYCOPROTEINS; MACROPHAGES; MONOLAYERS; PEPTIDES; PLATINUM COMPOUNDS; RADIOTHERAPY; TISSUE CULTURE;

CELL DEATH;

ANTRUM MUCOSAL PROTEIN PEPTIDE; CISPLATIN; PEPTIDE; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CONTROLLED STUDY; ERYTHEMA; FLOW CYTOMETRY; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; KERATINOCYTE; MALE; MICROVASCULAR ENDOTHELIAL CELL; NONHUMAN; ORAL MUCOSITIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RADIATION DOSE; ULCER;

ANIMALS; APOPTOSIS; CELL LINE; CRICETINAE; CYTOPROTECTION; DRUG EVALUATION, PRECLINICAL; ENDOTHELIAL CELLS; EPITHELIAL CELLS; HUMANS; MESOCRICETUS; PEPTIDE FRAGMENTS; PEPTIDE HORMONES; RADIATION INJURIES, EXPERIMENTAL; STOMATITIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84862802009     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2012.01.006     Document Type: Article

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