Knockdown of the nucleosome binding protein 1 inhibits the growth and invasion of clear cell renal cell carcinoma cells in vitro and in vivo

Journal of Experimental and Clinical Cancer Research

Volumn 31, Issue 1, 2012, Pages

  Ji, Shi Qi ^a,b,c   Yao, Lin ^a,b,c   Zhang, Xiao Yu ^a,b,c   Li, Xue Song ^a,b,c   Zhou, Li Qun ^a,b,c  

^a PEKING UNIVERSITY FIRST HOSPITAL   (China)

^b PEKING UNIVERSITY   (China)

^c NATIONAL UROLOGICAL CANCER CENTER   (China)

Author keywords

Apoptosis; Cell cycle; Clear cell renal cell carcinoma; MMPs; NSBP1

Indexed keywords

BETA ACTIN; BINDING PROTEIN; CYCLIN B1; CYCLIN D1; GELATINASE A; GELATINASE B; MESSENGER RNA; NUCLEOSOME BINDING PROTEIN 1; PROTEIN BAX; PROTEIN BCL 2; PROTEIN C FOS; PROTEIN C JUN; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; HIGH MOBILITY GROUP N PROTEIN; HMGN5 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GRADING; CANCER GROWTH; CANCER INVASION; CANCER MODEL; CANCER PATIENT; CARCINOGENESIS; CELL CYCLE ARREST; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CARCINOMA; KIDNEY PARENCHYMA; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR XENOGRAFT; WESTERN BLOTTING; ANIMAL; CELL LINE; DRUG SCREENING; GENE EXPRESSION; GENE SILENCING; GENETICS; KIDNEY TUMOR; MIDDLE AGED; PATHOLOGY;

AGED; AGED, 80 AND OVER; ANIMALS; CARCINOMA, RENAL CELL; CELL LINE; CELL PROLIFERATION; GENE EXPRESSION; GENE SILENCING; HMGN PROTEINS; HUMANS; KIDNEY NEOPLASMS; MICE; MICE, NUDE; MIDDLE AGED; NEOPLASM INVASIVENESS; RNA INTERFERENCE; TRANS-ACTIVATORS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84862796767     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/1756-9966-31-22     Document Type: Article

References (22)

1. The epidemiology of renal cell carcinoma. Ljungberg B, Campbell SC, Choi HY, Jacqmin D, Lee JE, Weikert S, Kiemeney LA, Eur Urol 2011 60 615 621 10.1016/j.eururo.2011.06.049 21741761
2. HMG chromosomal proteins in development and disease. Hock R, Furusawa T, Ueda T, Bustin M, Trends Cell Biol 2007 17 72 79 10.1016/j.tcb.2006.12.001 17169561 (Pubitemid 46206113)
3. The NSBP1 expression is up-regulated in prostate cancer cell. Wang JW, Zhou LQ, Yang XZ, Ai JK, Xin DQ, Na YQ, Guo YL, Basic Med Sci Clin 2004 24 393 397
4. Effect of nucleosomal binding protein 1 in androgen-independent prostatic carcinoma. Huang C, Zhou LQ, Song G, Zhong hua Yi Xue Za Zhi 2008 88 657 660 (Pubitemid 351756610)
5. Overexpression of the Axl tyrosine kinase receptor in cutaneous SCC-derived cell lines and tumours. Green J, Ikram M, Vyas J, Patel N, Proby CM, Ghali L, Leigh IM, O'Toole EA, Storey A, Br J Cancer 2006 94 1446 1451 10.1038/sj.bjc.6603135 16641895 (Pubitemid 43772279)
6. Gene expression profile analysis of an isogenic tumour metastasis model reveals a functional role for oncogene AF1Q in breast cancer metastasis. Li DQ, Hou YF, Wu J, Chen Y, Lu JS, Di GH, Ou ZL, Shen ZZ, Ding J, Shao ZM, Eur J Cancer 2006 42 3274 3286 10.1016/j.ejca.2006.07.008 16979889 (Pubitemid 44872944)
7. Persistent hypomethylation in the promoter of nucleosomal binding protein1 (Nsbp1) correlates with overexpression of Nsbp1 in mouse uteri neonatally exposed to diethylstilbestrol or genistein. Tang WY, Newbold R, Mardilovich K, Jefferson W, Cheng RY, Medvedovic M, Ho SM, Endocrinology 2008 149 5922 5931 10.1210/en.2008-0682 18669593
8. Effect of inhibiting nucleosomal binding protein 1 on proliferation of human prostate cancer cell line LNCaP. Zhou LQ, Song G, He ZS, Hao JR, Na YQ, Chin Med J 2007 86 404 408 (Pubitemid 46647504)
9. Downregulation of the nucleosome-binding protein 1 (NSBP1) gene can inhibit the in vitro and in vivo proliferation of prostate cancer cells. Jiang N, Zhou LQ, Zhang XY, Asian J Androl 2010 12 709 717 10.1038/aja.2010.39 20531280
10. Increased matrix metalloproteinase activation in esophageal squamous cell carcinoma. Mukherjee S, Roth MJ, Dawsey SM, Yan W, Rodriguez-Canales J, Erickson HS, Hu N, Goldstein AM, Taylor PR, Richardson AM, Tangrea MA, Chuaqui RF, Emmert-Buck MR, J Transl Med 2010 8 91 10.1186/1479-5876-8-91 20920372
11. Tissue factor in cancer and angiogenesis: the molecular link between genetic tumor progression, tumor neovascularization, and cancer coagulopathy. Rak J, Milsom C, May L, Klement P, Yu J, Semin Thromb Hemost 2006 32 54 70 Review 10.1055/s-2006-933341 16479463
12. HMGN5/NSBP1: A new member of the HMGN protein family that affects chromatin structure and function. Rochman M, Malicet C, Bustin M, Biochim Biophys Acta 2010 1799 86 92 20123071
13. Targeting of high mobility group-14/-17 proteins in chromatin is independent of DNA sequence. Shirakawa H, Herrera JE, Bustin M, Postnikov Y, J Biol Chem 2000 275 37937 37944 10.1074/jbc.M000989200 10973947 (Pubitemid 32004914)
14. HMGN dynamics and chromatin function. Catez F, Lim JH, Hock R, Postnikov YV, Bustin M, Biochem Cell Biol 2003 81 113 122 10.1139/o03-040 12897844 (Pubitemid 37076233)
15. The interaction of NSBP1/HMGN5 with nucleosomes in euchromatin counteracts linker histone-mediated chromatin compaction and modulates transcription, Mol. Rochman M, Postnikov Y, Correll S, Malicet C, Wincovitch S, Karpova TS, McNally JG, Wu X, Bubunenko NA, Grigoryev S, Bustin M, Cell 2009 35 642 656
16. HMGN proteins act in opposition to ATP-dependent chromatin remodeling factors to restrict nucleosome mobility. Rattner BP, Yusufzai T, Kadonaga JT, Mol Cell 2009 34 620 626 10.1016/j.molcel.2009.04.014 19524541
17. Induction of G2/M arrest and apoptosis by sesquiterpene lactones in human melanoma cell lines. Rozenblat S, Grossman S, Bergman M, Gottlieb H, Cohen Y, Dovrat S, Biochem Pharmacol 2008 75 369 382 10.1016/j.bcp.2007.08.024 17919456 (Pubitemid 350298461)
18. CyclinB1 expression is elevated and mitosis is delayed in HeLa cells expressing autonomous CaMKII. Beauman SR, Campos B, Kaetzel MA, Dedmana JR, Cell Signal 2003 15 1049 1057 10.1016/S0898-6568(03)00068-8 14499348 (Pubitemid 37130163)
19. Avian Reovirus Nonstructural Protein p17-Induced G2/M Cell Cycle Arrest and Host Cellular Protein Translation Shutoff Involve Activation of p53-Dependent Pathways. Chulu Julius LC, Huang Wei R, Wang L, Shih Wen L, Liu Hung J, J Virol 2010 84 7683 7694 10.1128/JVI.02604-09 20484520
20. Downregulation of SPARC expression decreases gastric cancer cellular invasion and survival. Yin J, Chen G, Liu Y, Liu S, Wang P, Wan Y, Wang X, Zhu J, Gao H, J Exp Clin Cancer Res 2010 29 59 10.1186/1756-9966-29-59 20525171
21. Tissue-based molecular markers for renal cell carcinoma. Rink M, Chun FK, Robinson B, Sun M, Karakiewicz PI, Bensalah K, Fisch M, Scherr DS, Lee RK, Margulis V, Shariat SF, Minerva Urol Nefrol 2011 63 293 308 21996985
22. Silibinin inhibits the invasion and migration of renal carcinoma 786-O cells in vitro, inhibits the growth of xenografts in vivo and enhances chemosensitivity to 5-fluorouracil and paclitaxel. Chang HR, Chen PN, Yang SF, Sun YS, Wu SW, Hung TW, Lian JD, Chu SC, Hsieh YS, Mol Carcinog 2011 50 811 823 10.1002/mc.20756 21574189