Folic acid deficiency inhibits neural rosette formation and neuronal differentiation from rhesus monkey embryonic stem cells

Journal of Neuroscience Research

Volumn 90, Issue 7, 2012, Pages 1382-1391

  Chen, Yongchang ^a,b,c,d   Wang, Zhengbo ^a,b   Xie, Yunhua ^a,b   Guo, Xiangyu ^a,b,c   Tang, Xianghui ^a,b   Wang, Shufen ^a,b   Yang, Shihua ^a,b,e   Chen, Kai ^a,b   Niu, Yuyu ^a,b,c   Ji, Weizhi ^a,b,c  

^a KUNMING INSTITUTE OF ZOOLOGY   (China)

^b Yunnan Key Laboratory of Animal Reproductive Biology   (China)

^c Kunming Biomed International   (China)

^d UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^e KUNMING UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Folic acid; Neural rosette; Neuronal differentiation; Rhesus monkey embryonic stem cells

Indexed keywords

FOLIC ACID; METHOTREXATE; NESTIN; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR SOX1; VIMENTIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYOID BODY; EMBRYONIC STEM CELL; FOLIC ACID DEFICIENCY; GLIA CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; NERVE CELL DIFFERENTIATION; NEURAL TUBE DEFECT; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHESUS MONKEY; ROSETTE FORMATION;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; EMBRYONIC STEM CELLS; FOLIC ACID; FOLIC ACID DEFICIENCY; MACACA MULATTA; MICE; NEURAL INHIBITION; NEURAL STEM CELLS; NEURONS;

EID: 84862794956     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.23030     Document Type: Article

References (29)

1. Atkinson S, Armstrong L. 2008. Epigenetics in embryonic stem cells: regulation of pluripotency and differentiation. Cell Tissue Res 331: 23-29.
2. Berry RJ, Li Z, Erickson JD, Li S, Moore CA, Wang H, Mulinare J, Zhao P, Wong LY, Gindler J, Hong SX, Correa A. 1999. Prevention of neural-tube defects with folic acid in China. China-U.S. Collaborative Project for Neural Tube Defect Prevention. N Engl J Med 341: 1485-1490.
3. Blom HJ, Shaw GM, den HM, Finnell RH. 2006. Neural tube defects and folate: case far from closed. Nat Rev Neurosci 7: 724-731.
4. Bondy SC, Campbell A. 2005. Developmental neurotoxicology. J Neurosci Res 81: 605-612.
5. Clarke J. 2009. Role of polarized cell divisions in zebrafish neural tube formation. Curr Opin Neurobiol 19: 134-138.
6. + T lymphocytes in vitro. J Immunol 173: 3186-3192.
7. Courtemanche C, Huang AC, Elson-Schwab I, Kerry N, Ng BY, Ames BN. 2004b. Folate deficiency and ionizing radiation cause DNA breaks in primary human lymphocytes: a comparison. FASEB J 18: 209-211.
8. Czeizel AE. 2004. Folic acid and the prevention of neural-tube defects. N Engl J Med 350: 2209-2211.
9. Czeizel AE, Dudas I. 1992. Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med 327: 1832-1835.
10. Elkabetz Y, Studer L. 2008. Human ESC-derived neural rosettes and neural stem cell progression. Cold Spring Harbor Symp Quant Biol 73: 377-387.
11. Elkabetz Y, Panagiotakos G, Al SG, Socci ND, Tabar V, Studer L. 2008. Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage. Genes Dev 22: 152-165.
12. Gan Q, Yoshida T, McDonald OG, Owens GK. 2007. Concise review: epigenetic mechanisms contribute to pluripotency and cell lineage determination of embryonic stem cells. Stem Cells 25: 2-9.
13. Gaspard N, Vanderhaeghen P. 2010. Mechanisms of neural specification from embryonic stem cells. Curr Opin Neurobiol 20: 37-43.
14. Hatse S, De CE, Balzarini J. 1999. Role of antimetabolites of purine and pyrimidine nucleotide metabolism in tumor cell differentiation. Biochem Pharmacol 58: 539-555.
15. Hernandez-Diaz S, Werler MM, Walker AM, Mitchell AA. 2001. Neural tube defects in relation to use of folic acid antagonists during pregnancy. Am J Epidemiol 153: 961-968.
16. Hirabayashi Y, Gotoh Y. 2010. Epigenetic control of neural precursor cell fate during development. Nat Rev Neurosci 11: 377-388.
17. Hwang IK, Yoo KY, Suh HW, Kim YS, Kwon DY, Kwon YG, Yoo JH, Won MH. 2008. Folic acid deficiency increases delayed neuronal death, DNA damage, platelet endothelial cell adhesion molecule-1 immunoreactivity, and gliosis in the hippocampus after transient cerebral ischemia. J Neurosci Res 86: 2003-2015.
18. Jia DY, Liu HJ, Wang FW, Liu SM, Ling EA, Liu K, Hao AJ. 2008. Folic acid supplementation affects apoptosis and differentiation of embryonic neural stem cells exposed to high glucose. Neurosci Lett 440: 27-31.
19. Juriloff DM, Harris MJ. 2000. Mouse models for neural tube closure defects. Hum Mol Genet 9: 993-1000.
20. Mattson MP, Shea TB. 2003. Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders. Trends Neurosci 26: 137-146.
21. Milunsky A, Jick H, Jick SS, Bruell CL, MacLaughlin DS, Rothman KJ, Willett W. 1989. Multivitamin/folic acid supplementation in early pregnancy reduces the prevalence of neural tube defects. JAMA 262: 2847-2852.
22. Mulinare J, Cordero JF, Erickson JD, Berry RJ. 1988. Periconceptional use of multivitamins and the occurrence of neural tube defects. JAMA 260: 3141-3145.
23. Pankratz MT, Li XJ, Lavaute TM, Lyons EA, Chen X, Zhang SC. 2007. Directed neural differentiation of human embryonic stem cells via an obligated primitive anterior stage. Stem Cells 25: 1511-1520.
24. Sato K, Kanno J, Tominaga T, Matsubara Y, Kure S. 2006. De novo and salvage pathways of DNA synthesis in primary cultured neurall stem cells. Brain Res 1071: 24-33.
25. Smithells RW, Nevin NC, Seller MJ, Sheppard S, Harris R, Read AP, Fielding DW, Walker S, Schorah CJ, Wild J. 1983. Further experience of vitamin supplementation for prevention of neural tube defect recurrences. Lancet 1: 1027-1031.
26. Thomson JA, Kalishman J, Golos TG, Durning M, Harris CP, Becker RA, Hearn JP. 1995. Isolation of a primate embryonic stem cell line. Proc Natl Acad Sci U S A 92: 7844-7848.
27. Toriello HV. 2005. Folic acid and neural tube defects. Genet Med 7: 283-284.
28. Zhang SC. 2006. Neural subtype specification from embryonic stem cells. Brain Pathol 16: 132-142.
29. Zhang SC, Wernig M, Duncan ID, Brustle O, Thomson JA. 2001. In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nat Biotechnol 19: 1129-1133.