Nimesulide inhibited the growth of hypopharyngeal carcinoma cells via suppressing Survivin expression

Head and Neck Oncology

Volumn 4, Issue 1, 2012, Pages

  Tian, Jia Jun ^a   Lu, Su Mei ^b   Yu, Liang ^a   Ma, Ju Ke ^a   Mu, Ya Kui ^a   Wang, Hai Bo ^a,b   Xu, Wei ^a  

^a SHANDONG UNIVERSITY   (China)

^b Shandong Clinic Research Institute   (China)

Author keywords

Cell growth; COX 2; Hypopharyngeal carcinoma; Nimesulide

Indexed keywords

CASPASE 3; CYCLOOXYGENASE 2; MESSENGER RNA; NIMESULIDE; PROTEIN BAX; PROTEIN BCL 2; SURVIVIN;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CARCINOMA CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOCHEMISTRY; DOWN REGULATION; DRUG EFFICACY; DRUG SENSITIVITY; FLOW CYTOMETRY; GENE EXPRESSION; GROWTH INHIBITION; HYPOPHARYNX CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

CARCINOMA, SQUAMOUS CELL; CELL GROWTH PROCESSES; CELL LINE, TUMOR; CYCLOOXYGENASE 2 INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEAD AND NECK NEOPLASMS; HUMANS; HYPOPHARYNGEAL NEOPLASMS; INHIBITOR OF APOPTOSIS PROTEINS; SULFONAMIDES;

EID: 84862789004     PISSN: None     EISSN: 17583284     Source Type: Journal    
DOI: 10.1186/1758-3284-4-7     Document Type: Article

References (19)

1. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Tsujii M, DuBois RN, Cell 1995 83 3 493 501 10.1016/0092-8674(95)90127-2 8521479
2. Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast. Hu M, Peluffo G, Chen H, Gelman R, Schnitt S, et al. PNAS 2009 106 9 3372 3377 10.1073/pnas.0813306106 19218449
3. Prognostic significance of elevated cyclooxygenase-2 expression in breast cancer. Ristimaki A, Sivula A, Lundin J, Lundin M, Salminen T, et al. Cancer Res 2002 62 3 632 635 11830510 (Pubitemid 34126931)
4. Effects of the inhibition of cyclooxygenase-2 on human esophageal cancer cells: inhibition of cell proliferation and induction of apoptosis. Zhang L, Tu J, Yu ZL, Wu YD, Xu CM, et al. Pathol Oncol Res 2010 16 1 39 45 10.1007/s12253-009-9185-6 19633925
5. Effect of celecoxib on E-cadherin, VEGF, Microvessel density and apoptosis in gastric cancer. Zhou Y, Ran J, Tang C, Wu J, Honghua L, et al. Cancer Biol Ther 2007 6 2 269 275 10.4161/cbt.6.2.3629 17224647 (Pubitemid 46641634)
6. Validating survivin as a cancer therapeutic target. Altieri DC, Nat Rev Cancer 2003 3 1 46 54 10.1038/nrc968 12509766 (Pubitemid 37328886)
7. Survivin in apoptosis control and cell cycle regulation in cancer. Altieri DC, Prog Cell Cycle Res 2003 5 447 452 14593739
8. The effects of cyclooxygenase-2 expression in prostate cancer cells: modulation of response to cytotoxic agents. Mehar A, Macanas-Pirard P, Mizokami A, Takahashi Y, Kass GE, et al. J Pharmacol Exp Ther 2008 324 3 1181 1187 18089846 (Pubitemid 351397841)
9. Clinicopathological significance of cyclooxygenase-2 expression in hypopharyngeal squamous cell carcinoma. Goto R, Hoshikawa H, Fujii T, Indo K, Yoshino K, et al. Oncol Rep 2008 19 3 645 650 18288396 (Pubitemid 351330430)
10. Cyclo-oxygenase 2 expression in laryngeal squamous cell carcinoma and its clinical correlates. Bayazit YA, Buyukberber S, Sari I, Camci C, Ozer E, et al. ORL J Otorhinolaryngol Relat Spec 2004 66 2 65 9 10.1159/000077797 15162003 (Pubitemid 38721112)
11. A COX-2 inhibitor nimesulide analog selectively induces apoptosis in Her2 overexpressing breast cancer cells via cytochrome c dependent mechanisms. Chen B, Su B, Chen S, Biochem Pharmacol 2009 77 12 1787 1794 10.1016/j.bcp.2009.03. 015 19428334
12. Effects of a selective cyclooxygenase-2 inhibitor, nimesulide, on the growth of ovariancarcinoma in vivo. Li W, Zhang HH, Xu RJ, Zhuo GC, Hu YQ, et al. Med Oncol 2008 25 2 172 7 10.1007/s12032-007-9016-0 18488158
13. Nicotine enhances migration and invasion of human esophageal squamous carcinoma cells which is inhibited by nimesulide. Zong Y, Zhang ST, Zhu ST, World J Gastroenterol 2009 15 20 2500 2505 10.3748/wjg.15.2500 19469000
14. Antitumor enhancement of celecoxib, a selective Cyclooxygenase-2 inhibitor, in a Lewis lung carcinoma expressing Cyclooxygenase-2. Park W, Oh YT, Han JH, Pyo H, J Exp Clin Cancer Res 2008 27 66 10.1186/1756-9966-27-66 19000324
15. siRNA targeting survivin inhibits growth and induces apoptosis in human renal clear cell carcinoma 786-O cells. Zhang Y, Chen ZD, Du CJ, Xu G, Luo W, Pathol Res Pract 2009 205 12 823 827 10.1016/j.prp.2009.06.018 19628339
16. Down-regulation of survivin in growth inhibition of hepatoma cells induced by a selective cyclooxygenase-2 inhibitor. Song IH, Kim DW, Shin KC, Shin HD, Yun SY, et al. Korean J Hepatol 2008 14 3 351 359 10.3350/kjhep.2008. 14.3.351 18815458
17. Celecoxib inhibits the expression of survivin via the suppression of promoter activity in human colon cancer cells. Sakoguchi-Okada N, Takahashi-Yanaga F, Fukada K, Shiraishi F, Taba Y, et al. Biochem Pharmacol 2007 73 9 1318 1329 10.1016/j.bcp.2006.12.033 17270149 (Pubitemid 46452589)
18. Differential roles for the coactivators CBP and p300 on TCF/beta-catenin-mediated survivin gene expression. Ma H, Nguyen C, Lee KS, Kahn M, Oncogene 2005 24 22 3619 3631 10.1038/sj.onc.1208433 15782138 (Pubitemid 40756231)
19. Survivin inhibition is critical for Bcl-2 inhibitor-induced apoptosis in hepatucellular carcinoma cells. Zhao X, Ogunwobi OO, Liu C, PLos One 2011 6 8 21980 10.1371/journal.pone.0021980 21829603