-
1
-
-
0042027816
-
Treatment of acute promyelocytic leukemia: strategy toward further increase of cure rate
-
Ohno R., Asou N., Ohnishi K. Treatment of acute promyelocytic leukemia: strategy toward further increase of cure rate. Leukemia 2003, 17:1454-1463.
-
(2003)
Leukemia
, vol.17
, pp. 1454-1463
-
-
Ohno, R.1
Asou, N.2
Ohnishi, K.3
-
2
-
-
19944432294
-
Phase I study of a novel recombinant human soluble thrombomodulin, ART-123
-
Moll S., Lindley C., Pescatore S., et al. Phase I study of a novel recombinant human soluble thrombomodulin, ART-123. J Thromb Haemost 2004, 2:1745-1751.
-
(2004)
J Thromb Haemost
, vol.2
, pp. 1745-1751
-
-
Moll, S.1
Lindley, C.2
Pescatore, S.3
-
3
-
-
0023374585
-
Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation
-
Suzuki K., Kusumoto H., Deyashiki Y., et al. Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation. EMBO J 1987, 6:1891-1897.
-
(1987)
EMBO J
, vol.6
, pp. 1891-1897
-
-
Suzuki, K.1
Kusumoto, H.2
Deyashiki, Y.3
-
4
-
-
0025174705
-
Structure and function of thrombomodulin: a natural anticoagulant
-
Dittman W.A., Majerus P.W. Structure and function of thrombomodulin: a natural anticoagulant. Blood 1990, 75:329-336.
-
(1990)
Blood
, vol.75
, pp. 329-336
-
-
Dittman, W.A.1
Majerus, P.W.2
-
5
-
-
20444427991
-
The anticoagulation protein C pathway
-
Dahlback B., Villoutreix B.O. The anticoagulation protein C pathway. FEBS Lett 2005, 579:3310-3316.
-
(2005)
FEBS Lett
, vol.579
, pp. 3310-3316
-
-
Dahlback, B.1
Villoutreix, B.O.2
-
6
-
-
33845513582
-
Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: results of a phase III, randomized, double-blind clinical trial
-
Saito H., Maruyama I., Shimazaki S., et al. Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: results of a phase III, randomized, double-blind clinical trial. J Thromb Haemost 2007, 5:31-41.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 31-41
-
-
Saito, H.1
Maruyama, I.2
Shimazaki, S.3
-
7
-
-
77956265194
-
Use of recombinant human soluble thrombomodulin in the management of HELLP syndrome complicated by DIC
-
Ikezoe T., Ikenoue N., Uchikawa N., Kojima S., Fukaya T., Yokoyama A. Use of recombinant human soluble thrombomodulin in the management of HELLP syndrome complicated by DIC. Thromb Res 2010, 126:e238-e240.
-
(2010)
Thromb Res
, vol.126
-
-
Ikezoe, T.1
Ikenoue, N.2
Uchikawa, N.3
Kojima, S.4
Fukaya, T.5
Yokoyama, A.6
-
8
-
-
78149280175
-
Successful treatment of thrombotic thrombocytopenic purpura associated with systemic lupus erythematosus with recombinant human soluble thrombomodulin
-
Sakai M., Ikezoe T., Bandobashi K., Yokoyama A. Successful treatment of thrombotic thrombocytopenic purpura associated with systemic lupus erythematosus with recombinant human soluble thrombomodulin. Thromb Res 2010, 126:e392-e393.
-
(2010)
Thromb Res
, vol.126
-
-
Sakai, M.1
Ikezoe, T.2
Bandobashi, K.3
Yokoyama, A.4
-
9
-
-
77950628343
-
Successful treatment of transplantation-associated thrombotic microangiopathy with recombinant human soluble thrombomodulin
-
Sakai M., Ikezoe T., Bandobashi K., Togitani K., Yokoyama A. Successful treatment of transplantation-associated thrombotic microangiopathy with recombinant human soluble thrombomodulin. Bone Marrow Transplant 2010, 45:803-805.
-
(2010)
Bone Marrow Transplant
, vol.45
, pp. 803-805
-
-
Sakai, M.1
Ikezoe, T.2
Bandobashi, K.3
Togitani, K.4
Yokoyama, A.5
-
10
-
-
77950624556
-
Successful treatment of sinusoidal obstructive syndrome after hematopoietic stem cell transplantation with recombinant human soluble thrombomodulin
-
Ikezoe T., Togitani K., Komatsu N., Isaka M., Yokoyama A. Successful treatment of sinusoidal obstructive syndrome after hematopoietic stem cell transplantation with recombinant human soluble thrombomodulin. Bone Marrow Transplant 2010, 45:783-785.
-
(2010)
Bone Marrow Transplant
, vol.45
, pp. 783-785
-
-
Ikezoe, T.1
Togitani, K.2
Komatsu, N.3
Isaka, M.4
Yokoyama, A.5
-
11
-
-
79953703447
-
Recombinant human soluble thrombomodulin counteracts capillary leakage associated with engraftment syndrome
-
Ikezoe T., Takeuchi A., Taniguchi A., Togitani K., Yokoyama A. Recombinant human soluble thrombomodulin counteracts capillary leakage associated with engraftment syndrome. Bone Marrow Transplant 2011, 46:616-618.
-
(2011)
Bone Marrow Transplant
, vol.46
, pp. 616-618
-
-
Ikezoe, T.1
Takeuchi, A.2
Taniguchi, A.3
Togitani, K.4
Yokoyama, A.5
-
12
-
-
0030861004
-
Thrombomodulin is a new biological and prognostic marker for breast cancer: an immunohistochemical study
-
Kim S.J., Shiba E., Ishii H., et al. Thrombomodulin is a new biological and prognostic marker for breast cancer: an immunohistochemical study. Anticancer Res 1997, 17:2319-2323.
-
(1997)
Anticancer Res
, vol.17
, pp. 2319-2323
-
-
Kim, S.J.1
Shiba, E.2
Ishii, H.3
-
13
-
-
33646496599
-
Thrombomodulin expression in colorectal carcinoma is protective and correlates with survival
-
Hanly A.M., Redmond M., Winter D.C., et al. Thrombomodulin expression in colorectal carcinoma is protective and correlates with survival. Br J Cancer 2006, 94:1320-1325.
-
(2006)
Br J Cancer
, vol.94
, pp. 1320-1325
-
-
Hanly, A.M.1
Redmond, M.2
Winter, D.C.3
-
14
-
-
77958127758
-
Decreased expression of thrombomodulin is correlated with tumor cell invasiveness and poor prognosis in nonsmall cell lung cancer
-
Liu P.L., Tsai J.R., Chiu C.C., et al. Decreased expression of thrombomodulin is correlated with tumor cell invasiveness and poor prognosis in nonsmall cell lung cancer. Mol Carcinog 2010, 49:874-881.
-
(2010)
Mol Carcinog
, vol.49
, pp. 874-881
-
-
Liu, P.L.1
Tsai, J.R.2
Chiu, C.C.3
-
15
-
-
0000686636
-
Thrombomodulin modulates growth of tumor cells independent of its anticoagulant activity
-
Zhang Y., Weiler-Guettler H., Chen J., et al. Thrombomodulin modulates growth of tumor cells independent of its anticoagulant activity. J Clin Invest 1998, 101:1301-1309.
-
(1998)
J Clin Invest
, vol.101
, pp. 1301-1309
-
-
Zhang, Y.1
Weiler-Guettler, H.2
Chen, J.3
-
16
-
-
34250771649
-
A novel treatment strategy targeting Aurora kinases in acute myelogenous leukemia
-
Ikezoe T., Yang J., Nishioka C., et al. A novel treatment strategy targeting Aurora kinases in acute myelogenous leukemia. Mol Cancer Ther 2007, 6:1851-1857.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1851-1857
-
-
Ikezoe, T.1
Yang, J.2
Nishioka, C.3
-
17
-
-
33744830869
-
HIV-1 protease inhibitor ritonavir potentiates the effect of 1,25-dihydroxyvitamin D3 to induce growth arrest and differentiation of human myeloid leukemia cells via down-regulation of CYP24
-
Ikezoe T., Bandobashi K., Yang Y., et al. HIV-1 protease inhibitor ritonavir potentiates the effect of 1,25-dihydroxyvitamin D3 to induce growth arrest and differentiation of human myeloid leukemia cells via down-regulation of CYP24. Leuk Res 2006, 30:1005-1011.
-
(2006)
Leuk Res
, vol.30
, pp. 1005-1011
-
-
Ikezoe, T.1
Bandobashi, K.2
Yang, Y.3
-
18
-
-
68549083470
-
Inhibition of mammalian target of rapamycin signaling potentiates the effects of all-trans retinoic acid to induce growth arrest and differentiation of human acute myelogenous leukemia cells
-
Nishioka C., Ikezoe T., Yang J., Gery S., Koeffler H.P., Yokoyama A. Inhibition of mammalian target of rapamycin signaling potentiates the effects of all-trans retinoic acid to induce growth arrest and differentiation of human acute myelogenous leukemia cells. Int J Cancer 2009, 125:1710-1720.
-
(2009)
Int J Cancer
, vol.125
, pp. 1710-1720
-
-
Nishioka, C.1
Ikezoe, T.2
Yang, J.3
Gery, S.4
Koeffler, H.P.5
Yokoyama, A.6
-
19
-
-
0034669985
-
HIV-1 protease inhibitors decrease proliferation and induce differentiation of human myelocytic leukemia cells
-
Ikezoe T., Daar E.S., Hisatake J., Taguchi H., Koeffler H.P. HIV-1 protease inhibitors decrease proliferation and induce differentiation of human myelocytic leukemia cells. Blood 2000, 96:3553-3559.
-
(2000)
Blood
, vol.96
, pp. 3553-3559
-
-
Ikezoe, T.1
Daar, E.S.2
Hisatake, J.3
Taguchi, H.4
Koeffler, H.P.5
-
20
-
-
3042751482
-
Insulin-like growth factor binding protein-3 antagonizes the effects of retinoids in myeloid leukemia cells
-
Ikezoe T., Tanosaki S., Krug U., et al. Insulin-like growth factor binding protein-3 antagonizes the effects of retinoids in myeloid leukemia cells. Blood 2004, 104:237-242.
-
(2004)
Blood
, vol.104
, pp. 237-242
-
-
Ikezoe, T.1
Tanosaki, S.2
Krug, U.3
-
21
-
-
33750483896
-
The antitumor effects of sunitinib (formerly SU11248) against a variety of human hematologic malignancies: enhancement of growth inhibition via inhibition of mammalian target of rapamycin signaling
-
Ikezoe T., Nishioka C., Tasaka T., et al. The antitumor effects of sunitinib (formerly SU11248) against a variety of human hematologic malignancies: enhancement of growth inhibition via inhibition of mammalian target of rapamycin signaling. Mol Cancer Ther 2006, 5:2522-2530.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2522-2530
-
-
Ikezoe, T.1
Nishioka, C.2
Tasaka, T.3
-
23
-
-
0027411150
-
Alanine-scanning mutagenesis of the epidermal growth factor-like domains of human thrombomodulin identifies critical residues for its cofactor activity
-
Nagashima M., Lundh E., Leonard J.C., Morser J., Parkinson J.F. Alanine-scanning mutagenesis of the epidermal growth factor-like domains of human thrombomodulin identifies critical residues for its cofactor activity. J Biol Chem 1993, 268:2888-2892.
-
(1993)
J Biol Chem
, vol.268
, pp. 2888-2892
-
-
Nagashima, M.1
Lundh, E.2
Leonard, J.C.3
Morser, J.4
Parkinson, J.F.5
-
24
-
-
0033119584
-
Annexin II and bleeding in acute promyelocytic leukemia
-
Menell J.S., Cesarman G.M., Jacovina A.T., McLaughlin M.A., Lev E.A., Hajjar K.A. Annexin II and bleeding in acute promyelocytic leukemia. N Engl J Med 1999, 340:994-1004.
-
(1999)
N Engl J Med
, vol.340
, pp. 994-1004
-
-
Menell, J.S.1
Cesarman, G.M.2
Jacovina, A.T.3
McLaughlin, M.A.4
Lev, E.A.5
Hajjar, K.A.6
-
25
-
-
0029050715
-
The epidermal growth factor-like domain of recombinant human thrombomodulin exhibits mitogenic activity for Swiss 3T3 cells
-
Hamada H., Ishii H., Sakyo K., Horie S., Nishiki K., Kazama M. The epidermal growth factor-like domain of recombinant human thrombomodulin exhibits mitogenic activity for Swiss 3T3 cells. Blood 1995, 86:225-233.
-
(1995)
Blood
, vol.86
, pp. 225-233
-
-
Hamada, H.1
Ishii, H.2
Sakyo, K.3
Horie, S.4
Nishiki, K.5
Kazama, M.6
-
26
-
-
36148996511
-
Thrombin-thrombomodulin connects coagulation and fibrinolysis: more than an in vitro phenomenon
-
Binette T.M., Taylor F.B., Peer G., Bajzar L. Thrombin-thrombomodulin connects coagulation and fibrinolysis: more than an in vitro phenomenon. Blood 2007, 110:3168-3175.
-
(2007)
Blood
, vol.110
, pp. 3168-3175
-
-
Binette, T.M.1
Taylor, F.B.2
Peer, G.3
Bajzar, L.4
-
27
-
-
0026573536
-
Retinoic acid stimulates expression of thrombomodulin, a cell surface anticoagulant glycoprotein, on human endothelial cells. Differences between up-regulation of thrombomodulin by retinoic acid and cyclic AMP
-
Horie S., Kizaki K., Ishii H., Kazama M. Retinoic acid stimulates expression of thrombomodulin, a cell surface anticoagulant glycoprotein, on human endothelial cells. Differences between up-regulation of thrombomodulin by retinoic acid and cyclic AMP. Biochem J 1992, 281:149-154.
-
(1992)
Biochem J
, vol.281
, pp. 149-154
-
-
Horie, S.1
Kizaki, K.2
Ishii, H.3
Kazama, M.4
-
28
-
-
0028145137
-
Thrombomodulin induction by all-trans retinoic acid is independent of HL-60 cells differentiation to neutrophilic cells
-
Kizaki K., Ishii H., Horie S., Kazama M. Thrombomodulin induction by all-trans retinoic acid is independent of HL-60 cells differentiation to neutrophilic cells. Thromb Haemost 1994, 72:573-577.
-
(1994)
Thromb Haemost
, vol.72
, pp. 573-577
-
-
Kizaki, K.1
Ishii, H.2
Horie, S.3
Kazama, M.4
|