Fabrication of cross-linked alginate beads using electrospraying for adenovirus delivery

International Journal of Pharmaceutics

Volumn 427, Issue 2, 2012, Pages 417-425

  Park, Hongkwan ^a   Kim, Pyung Hwan ^b   Hwang, Taewon ^a   Kwon, Oh Joon ^b   Park, Tae Joon ^a   Choi, Sung Wook ^c   Yun, Chae Ok ^b   Kim, Jung Hyun ^a  

^a Yonsei University   (South Korea)

^b Hanyang University   (South Korea)

^c The Catholic University of Korea   (South Korea)

Author keywords

Adenovirus; Alginate; Controlled release; Electrospraying; Encapsulation

Indexed keywords

ADENOVIRUS VECTOR; ALGINIC ACID; CALCIUM CHLORIDE; NANOBEAD; WATER;

ARTICLE; CANCER CELL; CONTROLLED STUDY; CROSS LINKING; DRUG DELIVERY SYSTEM; ELECTRIC POTENTIAL; ELECTROSPRAY; FLOW RATE; FLUORESCENCE ACTIVATED CELL SORTER; GENE EXPRESSION; GENETIC TRANSDUCTION; GLIOMA CELL; NANOENCAPSULATION; NANOFABRICATION; PRIORITY JOURNAL; SUSTAINED DRUG RELEASE;

ADENOVIRIDAE; ALGINATES; CALCIUM CHLORIDE; CELL LINE, TUMOR; CROSS-LINKING REAGENTS; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; ELECTROCHEMISTRY; EXCIPIENTS; FLOW CYTOMETRY; GENE THERAPY; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; NEOPLASMS; PARTICLE SIZE; SOLUTIONS; TRANSDUCTION, GENETIC;

EID: 84862779320     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.01.050     Document Type: Article

References (24)

1. N. Aggarwal, H. HogenEsch, P. Guo, A. North, M. Suckow, and S. Mittal Biodegradable alginate microspheres as a delivery system for naked DNA Can. J. Vet. Res. 63 1999 148 152
2. S.J. Beer, C.B. Matthews, C.S. Stein, B.D. Ross, J.M. Hilfinger, and B.L. Davidson Poly (lactic-glycolic) acid copolymer encapsulation of recombinant adenovirus reduces immunogenicity in vivo Gene Ther. 5 1998 740 746
3. B. Bugarski, Q. Li, M. Goosen, D. Poncelet, R. Neufeld, and G. Vunjak Electrostatic droplet generation: mechanism of polymer droplet formation AIChE J. 40 1994 1026 1031
4. S.W. Choi, I.W. Cheong, J.H. Kim, and Y. Xia Preparation of uniform microspheres using a simple fluidic device and their crystallization into close-packed lattices Small 5 2009 454 459
5. A. El-Aneed An overview of current delivery systems in cancer gene therapy J. Control. Release 94 2004 1 14
6. M. George, and T.E. Abraham pH sensitive alginate-guar gum hydrogel for the controlled delivery of protein drugs Int. J. Pharm. 335 2007 123 129
7. M.F.A. Goosen, A.S. Al-Ghafri, O.E. Mardi, M.I.J. Al-Belushi, H.A. Al-Hajri, E.S.E. Mahmoud, and E.C. Consolacion Electrostatic droplet generation for encapsulation of somatic tissue: assessment of high voltage power supply Biotechnol. Prog. 13 1997 497 502
8. Z.M. Huang, Y.Z. Zhang, M. Kotaki, and S. Ramakrishna A review on polymer nanofibers by electrospinning and their applications in nanocomposites Compos. Sci. Technol. 63 2003 2223 2253
9. Y. Jung, H.J. Park, P.H. Kim, J. Lee, W. Hyung, J. Yang, H. Ko, J.H. Sohn, J.H. Kim, Y.M. Huh, C.O. Yun, and S. Haam Retargeting of adenoviral gene delivery via Herceptin-PEG-adenovirus conjugates to breast cancer cells J. Control. Release 123 2007 164 171
10. 2+-alginate gel dissolution on release of dextran with different molecular weights J. Control. Release 58 1999 21 28
11. S. Koch, C. Schwinger, J. Kressler, C. Heinzen, and N. Rainov Alginate encapsulation of genetically engineered mammalian cells: comparison of production devices, methods and microcapsule characteristics J. Microencapsule 20 2003 303 316
12. C.M. Lee, H.J. Jeong, D.W. Kim, and K.Y. Lee Alginate/carboxymethyl scleroglucan hydrogels for controlled release of protein drugs Macromol. Res. 16 2008 429 433
13. H.J. Lim, H.D. Ghim, J.H. Choi, H.Y. Chung, and J.O. Lim Controlled release of BMP-2 from alginate nanohydrogels enhanced osteogenic differentiation of human bone marrow stromal cells Macromol. Res. 18 2010 787 792
14. S. Li, X. Wang, X. Zhang, R. Yang, H. Zhang, L. Zhu, and X. Hou Studies on alginate-chitosan microcapsules and renal arterial embolization in rabbits J. Control. Release 84 2002 87 98
15. A. Martinsen, G. Skjk-Bræk, and O. SmidsrØd Alginate as immobilization material. I. Correlation between chemical and physical properties of alginate gel beads Biotechnol. Bioeng. 33 1989 79 89
16. M.W. Pandori, D.A. Hobson, and T. Sano Adenovirus-microbead conjugates possess enhanced infectivity: a new strategy for localized gene delivery Virology 299 2002 204 212
17. S.A. Park, K.E. Park, and W. Kim Preparation of sodium alginate/poly (ethylene oxide) blend nanofibers with lecithin Macromol. Res. 18 2010 891 896
18. Y. Park, E. Kang, O.J. Kwon, T. Hwang, H. Park, J.M. Lee, J.H. Kim, and C.O. Yun Ionically crosslinked Ad/chitosan nanocomplexes processed by electrospinning for targeted cancer gene therapy J. Control. Release 148 2010 75 82
19. 2+- alginate beads Biotechnol. Bioeng. 79 2002 253 259
20. O. Smidsrod, G. Skjk-Bræk, and O. SmidsrØd Alginate as immobilization matrix for cells Trends Biotechnol. 8 1990 71 78
21. J.C. Steel, H. Cavanagh, M.A. Burton, D. Dingwall, and W. Kalle In vitro evaluation of ion-exchange microspheres for the sustained release of liposomal-adenoviral conjugates J. Control. Release 95 2004 601 611
22. B.L. Strand, O. Gaserød, B. Kulseng, T. Espevik, and G. Skjk-Bræk Alginate-polylysine-alginate microcapsules: effect of size reduction on capsule properties J. Microencapsul. 19 2002 615 630
23. P. Turner, A. Petch, and M. Al-Rubeai Encapsulation of viral vectors for gene therapy applications Biotechnol. Prog. 23 2007 423 429
24. W.J. Zhang, B.G. Li, C. Zhang, X.H. Xie, and T.T. Tang Biocompatibility and membrane strength of C3H10T1/2 cell-loaded alginate-based microcapsules Cytotherapy 10 2008 90 97