Effect of Ca2+-alginate gel dissolution on release of dextran with different molecular weights

Journal of Controlled Release

Volumn 58, Issue 1, 1999, Pages 21-28

  Kikuchi, Akihiko ^a   Kawabuchi, Minako ^b   Watanabe, Atsushi ^b   Sugihara, Masayasu ^b   Sakurai, Yasuhisa ^a   Okano, Teruo ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^b TOKYO WOMEN S MEDICAL UNIVERSITY MEDICAL CENTER EAST   (Japan)

Author keywords

Alginate dissolution; Calcium alginate gel; Dextran release; Oral delivery; Pulsatile release

Indexed keywords

CALCIUM ALGINATE; DEXTRAN; FLUORESCEIN ISOTHIOCYANATE; ALGINIC ACID; DRUG CARRIER; GLUCURONIC ACID; HEXURONIC ACID;

ARTICLE; DIFFUSION COEFFICIENT; DISSOLUTION; DRUG DELIVERY SYSTEM; DRUG RELEASE; GEL; MOLECULAR WEIGHT; PRIORITY JOURNAL; THERMODYNAMICS; CHEMISTRY; DIFFUSION; ION EXCHANGE CHROMATOGRAPHY; PH;

ALGINATES; CHROMATOGRAPHY, ION EXCHANGE; DEXTRANS; DIFFUSION; DRUG CARRIERS; FLUORESCEIN-5-ISOTHIOCYANATE; GELS; GLUCURONIC ACID; HEXURONIC ACIDS; HYDROGEN-ION CONCENTRATION; MOLECULAR WEIGHT;

EID: 0032588437     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(98)00141-2     Document Type: Article

References (23)

1. N. Ogawa, S. Ohdo, Chronopharmacological aspects in dose-concentration-response relationship, Drug Deliv. Syst. 7(2) (1992) 77-90.
2. Y. Motohashi, Chronopharmacodynamics and DDS, Drug Deliv. Syst. 7(3) (1992) 157-163.
3. T. Fukuda, Application of chronopharmacology to drug therapy, Jpn. J. Hosp. Pharm. 15(6) (1989) 383-390.
4. F. Pozzi, P. Furlani, A. Gazzaniga, S.S. Davis, I.R. Wilding, The TIME CLOCK system: a new oral dosage form for fast and complete release of drug after a predetermined lag time, J. Control. Release 31 (1994) 99-108.
5. T. Okano, N. Yui, M. Yokoyama, R. Yoshida, Advances in Polymeric Systems for Drug Delivery, Japanese Technology Reviews 4, Gordon and Breach, Yverdon, Switzerland, 1994.
6. J. Tamada, R. Langer, The development of polyanhydrides for drug delivery applications, J. Biomater. Sci., Polymer Ed. 3(4) (1992) 315-353.
7. K. Park, W.S.W. Shalaby, H. Park, Biodegradable Hydrogels for Drug Delivery, Technomic, Lancaster, Ch. 5, 1993, pp. 99-140.
8. P.G. Kibat, Y Igari, M.A. Wheatley, H.N. Eisen, R. Langer, Enzymatically activated microencapsulated liposomes can provide pulsatile drug release, FASEB J. 4 (1990) 2533-2539.
9. S. Shiraishi, T. Imai, M. Otagiri, Controlled-release preparation of indomethacin using calcium alginate gel, Biol. Pharm. Bull. 16(11) (1993) 1164-1168.
10. K. Tateshita, S. Sugawara, T. Imai, M. Otagiri, Preparation and evaluation of a controlled-release formulation of nifedipine using alginate gel beads, Biol. Pharm. Bull. 16(4) (1993) 420-424.
11. S. Sugawara, T. Imai, M. Otagiri, The controlled release of prednisolone using alginate gel, Pharm. Res. 11(2) (1994) 272-277.
12. Y. Murata, K. Nakada, E. Miyamoto, S. Kawashima, S.-H. Seo, Influence of erosion of calcium-induced alginate gel matrix on the release of brilliant blue, J. Control. Release 23 (1993) 21-26.
13. Y. Murata, T. Maeda, E. Miyamoto, T. Yamamoto, K. Murata, S. Kawashima, The in vitro sustained release of diclofenac from calcium-induced alginate gel beads, Drug Deliv. Syst. 8(2) (1993) 199-203.
14. C.-K. Kim, E.-J. Lee, The controlled release of blue dextran from alginate beads, Int. J. Pharm. 79 (1992) 11-19.
15. T. Yotsuyanagi, T. Ohkubo, T. Ohhashi, K. Ikeda, Calcium-induced gelation of alginic acid and pH-sensitive reswelling of dried gels, Chem. Pharm. Bull. 35(4) (1987) 1555-1563.
16. N. Segi, T. Yotsuyanagi, K. Ikeda, Interaction of calcium-induced alginate gel beads with propranolol, Chem. Pharm. Bull. 37(11) (1989) 3092-3095.
17. T. Yotsuyanagi, I. Yoshioka, N. Segi, K. Ikeda, Effects of monovalent metal ions and propranolol on the calcium association in calcium-induced alginate gel beads, Chem. Pharm. Bull. 38(11) (1990) 3124-3126.
18. T. Yotsuyanagi, I. Yoshioka, N. Segi, K. Ikeda, Acid-induced and calcium-induced gelation of alginic acid: bead formation and pH-dependent swelling, Chem. Pharm. Bull. 39(4) (1991) 1072-1074.
19. H. Tomida, C. Mizuo, C. Nakamura, S. Kiryu, Imipramine release from Ca-alginate gel beads, Chem. Pharm. Bull. 41(8) (1993) 1475-1477.
20. H. Tomida, C. Nakamura, H. Yoshitomi, S. Kiryu, Preparation of theophylline-loaded calcium alginate gel capsules and evaluation of their drug release characteristics, Chem. Pharm. Bull. 41(12) (1993) 2161-2165.
21. E.R. Morris, Molecular interactions in polysaccharide gelation, Br. Polymer J. 18 (1986) 14-21.
22. A. Kikuchi, M. Kawabuchi, M. Sugihara, Y. Sakurai, T. Okano, Pulsed dextran release from calcium-alginate gel beads, J. Control. Release 47 (1997) 21-29.
23. O. Smidsrod, Molecular basis for some physical properties of alginate in gel state, Faraday Discuss. Chem. Soc. 57 (1974) 263-274.