메뉴 건너뛰기




Volumn 35, Issue 1, 2012, Pages 42-48

Biosynthesis of proTRH-derived peptides in prohormone convertase 1 and 2 knockout mice

Author keywords

PC1; PC2, Neuropeptides; Prohormone convertases; Prohormone processing; proTRH; TRH

Indexed keywords

GLUTAMINE; GLYCINE; HISTIDINE; PEPTIDE; PROLACTIN; PROLINE; PROPROTEIN CONVERTASE 1; PROPROTEIN CONVERTASE 2; PROTIRELIN; THYROID HORMONE;

EID: 84862778671     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2012.02.024     Document Type: Article
Times cited : (13)

References (39)
  • 1
    • 0026047526 scopus 로고
    • Alteration of somatostatin but not growth hormone-releasing factor pituitary binding sites in obese Zucker rats
    • Abribat T, Finkelstein JA, Gaudreau P. Alteration of somatostatin but not growth hormone-releasing factor pituitary binding sites in obese Zucker rats. Regulatory Peptides 1991;36:263-70.
    • (1991) Regulatory Peptides , vol.36 , pp. 263-270
    • Abribat, T.1    Finkelstein, J.A.2    Gaudreau, P.3
  • 2
    • 0032526224 scopus 로고    scopus 로고
    • Sorting and storage during secretory granule biogenesis: Looking backward and looking forward
    • Arvan P, Castle D. Sorting and storage during secretory granule biogenesis: looking backward and looking forward. Biochem J 1998;332:593-610. (Pubitemid 28306683)
    • (1998) Biochemical Journal , vol.332 , Issue.3 , pp. 593-610
    • Arvan, P.1    Castle, D.2
  • 4
    • 0029829135 scopus 로고    scopus 로고
    • Intracellular sites of prothyrotropin-releasing hormone processing
    • DOI 10.1074/jbc.271.37.22736
    • Cruz IP, Nillni EA. Intracellular sites of prothyrotropin-releasing hormone processing. J Biol Chem 1996;271:22736-45. (Pubitemid 26304719)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.37 , pp. 22736-22745
    • De La, C.I.P.1    Nillni, E.A.2
  • 5
    • 12344302029 scopus 로고    scopus 로고
    • Significance of prohormone convertase 2, PC2, mediated initial cleavage at the proglucagon interdomain site, Lys70-Arg71, to generate glucagon
    • DOI 10.1210/en.2004-1118
    • Dey A, Lipkind GM, Rouille Y, Norrbom C, Stein J, Zhang C, et al. Significance of prohormone convertase 2, PC2, mediated initial cleavage at the proglucagon interdomain site, Lys70-Arg71, to generate glucagon. Endocrinology 2005;146:713-27. (Pubitemid 40129827)
    • (2005) Endocrinology , vol.146 , Issue.2 , pp. 713-727
    • Dey, A.1    Lipkind, G.M.2    Rouille, Y.3    Norrbom, C.4    Stein, J.5    Zhang, C.6    Carroll, R.7    Steiner, D.F.8
  • 7
    • 0029084820 scopus 로고
    • Processing of prothyrotropin-releasing hormone (Pro-TRH) by bovine intermediate lobe secretory vesicle membrane PC1 and PC2 enzymes
    • Friedman TC, Loh YP, Cawley NX, Birch NP, Huang SS, Jackson IM, et al. Processing of prothyrotropin-releasing hormone (Pro-TRH) by bovine intermediate lobe secretory vesicle membrane PC1 and PC2 enzymes. Endocrinology 1995;136:4462-72.
    • (1995) Endocrinology , vol.136 , pp. 4462-4472
    • Friedman, T.C.1    Loh, Y.P.2    Cawley, N.X.3    Birch, N.P.4    Huang, S.S.5    Jackson, I.M.6
  • 8
    • 0028048850 scopus 로고
    • Gene organization of the mouse pro-hormone and pro-protein convertase PC1
    • Ftouhi N, Day R, Mbikay M, Chretien M, Seidah NG. Gene organization of the mouse pro-hormone and pro-protein convertase PC1. DNA Cell Biol 1994;13:395-407. (Pubitemid 24295369)
    • (1994) DNA and Cell Biology , vol.13 , Issue.4 , pp. 395-407
    • Ftouhi, N.1    Day, R.2    Mbikay, M.3    Chretien, M.4    Seidah, N.G.5
  • 12
    • 0038731191 scopus 로고    scopus 로고
    • Thyroid hormone and uncoupling proteins
    • DOI 10.1016/S0014-5793(03)00320-X
    • Lanni A, Moreno M, Lombardi A, Goglia F. Thyroid hormone and uncoupling proteins. FEBS Lett 2003;543:5-10. (Pubitemid 36577217)
    • (2003) FEBS Letters , vol.543 , Issue.1-3 , pp. 5-10
    • Lanni, A.1    Moreno, M.2    Lombardi, A.3    Goglia, F.4
  • 13
    • 0022621305 scopus 로고
    • Thyrotropin-releasing hormone precursor: Characterization in rat brain
    • Lechan RM, Wu P, Jackson IMD, Wolfe H, Cooperman S, Mandel G, et al. Thyrotropin-releasing hormone precursor: characterization in rat brain. Science 1986;231:159-61. (Pubitemid 16154707)
    • (1986) Science , vol.231 , Issue.4734 , pp. 159-161
    • Lechan, R.M.1    Wu, P.2    Jackson, I.M.D.3
  • 14
    • 28844478947 scopus 로고    scopus 로고
    • Prohormone-convertase 1 processing enhances post-golgi sorting of prothyrotropin-releasing hormone-derived peptides
    • DOI 10.1074/jbc.M507193200
    • Mulcahy LR, Vaslet CA. Nillni EA. Prohormone-convertase 1 processing enhances post-Golgi sorting of prothyrotropin-releasing hormone-derived peptides. J Biol Chem 2005;280:39818-26. (Pubitemid 41779115)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.48 , pp. 39818-39826
    • Mulcahy, L.R.1    Vaslet, C.A.2    Nillni, E.A.3
  • 15
    • 0032774307 scopus 로고    scopus 로고
    • Neuroregulation of proTRH biosynthesis and processing
    • Nillni EA. Neuroregulation of ProTRH biosynthesis and processing. Endocrine 1999;10:185-99. (Pubitemid 29372964)
    • (1999) Endocrine , vol.10 , Issue.3 , pp. 185-199
    • Nillni, E.A.1
  • 16
    • 77950860422 scopus 로고    scopus 로고
    • Regulation of the hypothalamic thyrotropin releasing hormone (TRH) neuron by neuronal and peripheral inputs
    • Nillni EA. Regulation of the hypothalamic thyrotropin releasing hormone (TRH) neuron by neuronal and peripheral inputs. Front Neuroendocrinol 2010;31:134-56.
    • (2010) Front Neuroendocrinol , vol.31 , pp. 134-156
    • Nillni, E.A.1
  • 17
    • 0035104179 scopus 로고    scopus 로고
    • 178-199 and two novel peptides (pFQ7 and pSE14) derived from its processing, which are produced in the paraventricular nucleus of the rat hypothalamus, are regulated during suckling
    • DOI 10.1210/en.142.2.896
    • Nillni EA, Aird F, Seidah NG, Todd RB, Koenig JI. PreproTRH(178-199) and two novel peptides (pFQ7 and pSE14) derived from its processing, which are produced in the paraventricular nucleus of the rat hypothalamus, are regulated during suckling. Endocrinology 2001;142:896-906. (Pubitemid 32222440)
    • (2001) Endocrinology , vol.142 , Issue.2 , pp. 896-906
    • Nillni, E.A.1    Aird, F.2    Seidah, N.G.3    Todd, R.B.4    Koenig, J.I.5
  • 19
    • 0030457872 scopus 로고    scopus 로고
    • Identification of the thyrotropin-releasing hormone precursor, its processing products, and its coexpression with convertase 1 in primary cultures of hypothalamic neurons: Anatomic distribution of PC1 and PC2
    • Nillni EA, Luo LG, Jackson IM, McMillan P. Identification of the thyrotropin-releasing hormone precursor, its processing products, and its coexpression with convertase 1 in primary cultures of hypothalamic neurons: anatomic distribution of PC1 and PC2. Endocrinology 1996;137:5651-61.
    • (1996) Endocrinology , vol.137 , pp. 5651-5661
    • Nillni, E.A.1    Luo, L.G.2    Jackson, I.M.3    McMillan, P.4
  • 20
    • 0033305169 scopus 로고    scopus 로고
    • The biology of pro-thyrotropin-releasing hormone-derived peptides
    • Nillni EA, Sevarino KA. The biology of pro-thyrotropin-releasing hormone-derived peptides. Endocr Rev 1999;20:599-648. (Pubitemid 30650601)
    • (1999) Endocrine Reviews , vol.20 , Issue.5 , pp. 599-648
    • Nillni, E.A.1    Sevarino, K.A.2
  • 21
    • 0027513325 scopus 로고
    • Identification of the thyrotropin-releasing hormone-prohormone and its posttranslational processing in a transfected AtT20 tumoral cell line
    • DOI 10.1210/en.132.3.1260
    • Nillni EA, Sevarino KA, Jackson IM. Identification of the thyrotropin-releasing hormone-prohormone and its posttranslational processing in a transfected AtT20 tumoral cell line. Endocrinology 1993;132:1260-70. (Pubitemid 23068647)
    • (1993) Endocrinology , vol.132 , Issue.3 , pp. 1260-1270
    • Nillni, E.A.1    Sevarino, K.A.2    Jackson, I.M.D.3
  • 22
    • 0027511928 scopus 로고
    • 20 cells
    • DOI 10.1210/en.132.3.1271
    • Nillni EA, Sevarino KA, Jackson IM. Processing of proTRH to its intermediate products occurs before the packing into secretory granules of transfected AtT20 cells. Endocrinology 1993;132:1271-7. (Pubitemid 23068648)
    • (1993) Endocrinology , vol.132 , Issue.3 , pp. 1271-1277
    • Nillni, E.A.1    Sevarino, K.A.2    Jackson, I.M.D.3
  • 23
    • 33748051433 scopus 로고    scopus 로고
    • The role of prohormone convertase-2 in hypothalamic neuropeptide processing: A quantitative neuropeptidomic study
    • DOI 10.1111/j.1471-4159.2006.04067.x
    • Pan H, Che FY, Peng B, Steiner DF, Pintar JE, Fricker LD. The role of prohormone convertase-2 in hypothalamic neuropeptide processing: a quantitative neuropeptidomic study. J Neurochem 2006;98:1763-77. (Pubitemid 44298243)
    • (2006) Journal of Neurochemistry , vol.98 , Issue.6 , pp. 1763-1777
    • Pan, H.1    Che, F.-Y.2    Peng, B.3    Steiner, D.F.4    Pintar, J.E.5    Fricker, L.D.6
  • 24
    • 0025258485 scopus 로고
    • Release of thyrotropin and prolactin by a thyrotropin-releasing hormone (TRH) precursor, TRH-Gly: Conversion to TRH is sufficient for in vivo effects
    • Pekary AE, Stephens R, Simard M, Pang XP, Smith V, DiStefano 3rd JJ, et al. Release of thyrotropin and prolactin by a thyrotropin-releasing hormone (TRH) precursor, TRH-Gly: conversion to TRH is sufficient for in vivo effects. Neuroendocrinology 1990;52:618-25.
    • (1990) Neuroendocrinology , vol.52 , pp. 618-625
    • Pekary, A.E.1    Stephens, R.2    Simard, M.3    Pang, X.P.4    Smith, V.5    DiStefano III, J.J.6
  • 25
    • 34347271662 scopus 로고    scopus 로고
    • The biosynthesis and processing of neuropeptides: Lessons from prothyrotropin releasing hormone (proTRH)
    • Perello M, Nillni EA. The biosynthesis and processing of neuropeptides: lessons from prothyrotropin releasing hormone (proTRH). Front Biosci 2007;12:3554-65.
    • (2007) Front Biosci , vol.12 , pp. 3554-3565
    • Perello, M.1    Nillni, E.A.2
  • 26
    • 50649106484 scopus 로고    scopus 로고
    • Prothyrotropin-releasing hormone targets its processing products to different vesicles of the secretory pathway
    • Perello M, Stuart R, Nillni EA. Prothyrotropin-releasing hormone targets its processing products to different vesicles of the secretory pathway. J Biol Chem 2008;283:19936-47.
    • (2008) J Biol Chem , vol.283 , pp. 19936-19947
    • Perello, M.1    Stuart, R.2    Nillni, E.A.3
  • 27
    • 33745178513 scopus 로고    scopus 로고
    • The role of intracerebroventricular administration of leptin in the stimulation of prothyrotropin releasing hormone neurons in the hypothalamic paraventricular nucleus
    • DOI 10.1210/en.2005-1533
    • Perello M, Stuart RC, Nillni EA. The role of intracerebroventricular administration of leptin in the stimulation of prothyrotropin releasing hormone neurons in the hypothalamic paraventricular nucleus. Endocrinology 2006;147:3296-306. (Pubitemid 43901120)
    • (2006) Endocrinology , vol.147 , Issue.7 , pp. 3296-3306
    • Perello, M.1    Stuart, R.C.2    Nillni, E.A.3
  • 28
    • 0033038403 scopus 로고    scopus 로고
    • Thyroid hormone and other regulators of uncoupling proteins
    • Reitman ML, He Y, Gong DW. Thyroid hormone and other regulators of uncoupling proteins. Int J Obes Relat Metab Disord 1999;23(Suppl 6):S56-9. (Pubitemid 29322614)
    • (1999) International Journal of Obesity , vol.23 , Issue.SUPPL. 6
    • Reitman, M.L.1    He, Y.2    Gong, D.-W.3
  • 29
    • 0026633608 scopus 로고
    • Cloning of the mouse hypothalamic preprothyrotropin-releasing hormone (TRH) cDNA and tissue distribution of its mRNA
    • Satoh T, Yamada M, Monden T, Iizuka M, Mori M. Cloning of the mouse hypothalamic preprothyrotropin-releasing hormone (TRH) cDNA and tissue distribution of its mRNA. Brain Res Mol Brain Res 1992;14:131-5.
    • (1992) Brain Res Mol Brain Res , vol.14 , pp. 131-135
    • Satoh, T.1    Yamada, M.2    Monden, T.3    Iizuka, M.4    Mori, M.5
  • 30
    • 0030806930 scopus 로고    scopus 로고
    • Processing of prothyrotropin-releasing hormone by the family of prohormone convertases
    • DOI 10.1074/jbc.272.32.19958
    • Schaner P, Todd RB, Seidah NG, Nillni EA. Processing of prothyrotropin-releasing hormone by the family of prohormone convertases. J Biol Chem 1997;272:19958-68. (Pubitemid 27340097)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.32 , pp. 19958-19968
    • Schaner, P.1    Todd, R.B.2    Seidah, N.G.3    Nillni, E.A.4
  • 31
    • 0343307146 scopus 로고    scopus 로고
    • Eukaryotic protein processing: Endoproteolysis of precursor proteins
    • DOI 10.1016/S0958-1669(97)80036-5
    • Seidah NG, Chretien M. Eukaryotic protein processing: endoproteolysis of precursor proteins. Curr Opin Biotechnol 1997;8:602-7. (Pubitemid 27455338)
    • (1997) Current Opinion in Biotechnology , vol.8 , Issue.5 , pp. 602-607
    • Seidah, N.G.1    Chretien, M.2
  • 32
    • 0024832277 scopus 로고
    • Thyrotropin-releasing hormone (TRH) precursor processing. Characterization of mature TRH and non-TRH peptides synthesized by transfected mammalian cells
    • Sevarino KA, Goodman RH, Spiess J, Jackson IMD, Wu P. Thyrotropin-releasing hormone (TRH) precursor processing: characterization of mature TRH and nonTRH peptides synthesized by transfected mammalian cells. J Biol Chem 1989;264:21529-35. (Pubitemid 20028714)
    • (1989) Journal of Biological Chemistry , vol.264 , Issue.36 , pp. 21529-21535
    • Sevarino, K.A.1    Goodman, R.H.2    Spiess, J.3    Jackson, I.M.D.4    Wu, P.5
  • 33
    • 0025214491 scopus 로고
    • Identification of a human insulinoma cDNA encoding a novel mammalian protein structurally related to the yeast dibasic processing protease Kex2
    • Smeekens SP, Steiner DF. Identification of a human insulinoma cDNA encoding a novel mammalian protein structurally related to the yeast dibasic processing protease Kex2. J Biol Chem 1990;265:2997-3000.
    • (1990) J Biol Chem , vol.265 , pp. 2997-3000
    • Smeekens, S.P.1    Steiner, D.F.2
  • 35
    • 0016296191 scopus 로고
    • Stimulation of prolactin and growth hormone release by TRH infused into a hypophyisal portal vessel
    • Takahara J, Arimura A, Schally AV. Stimulation of prolactin and growth hormone release by TRH infused into a hypophyisal portal vessel. Proc Soc Exper Biol Med 1974;146:831-5.
    • (1974) Proc Soc Exper Biol Med , vol.146 , pp. 831-835
    • Takahara, J.1    Arimura, A.2    Schally, A.V.3
  • 36
    • 0014251806 scopus 로고
    • In vitro studies on mechanism of action of thyrotropin releasing factor
    • Wilber JF, Utiger RD. In vitro studies on mechanism of action of thyrotropin releasing factor. Proc Soc Exper Biol Med 1967;127:488-90.
    • (1967) Proc Soc Exper Biol Med , vol.127 , pp. 488-490
    • Wilber, J.F.1    Utiger, R.D.2
  • 37
    • 0029150808 scopus 로고
    • Activation of the thyrotropin-releasing hormone (TRH) receptor by a direct precursor of TRH, TRH-Gly
    • Yamada M, Iwasaki T, Satoh T, Monden T, Konaka S, Murakami M, et al. Activation of the thyrotropin-releasing hormone (TRH) receptor by a direct precursor of TRH, TRH-Gly. Neurosci Lett 1995;196:109-12.
    • (1995) Neurosci Lett , vol.196 , pp. 109-112
    • Yamada, M.1    Iwasaki, T.2    Satoh, T.3    Monden, T.4    Konaka, S.5    Murakami, M.6
  • 38
    • 75949114410 scopus 로고    scopus 로고
    • Neuropeptidomic analysis establishes a major role for prohormone convertase-2 in neuropeptide biosynthesis
    • Zhang X, Pan H, Peng B, Steiner DF, Pintar JE, Fricker LD. Neuropeptidomic analysis establishes a major role for prohormone convertase-2 in neuropeptide biosynthesis. J Neurochem 2010;112:1168-79.
    • (2010) J Neurochem , vol.112 , pp. 1168-1179
    • Zhang, X.1    Pan, H.2    Peng, B.3    Steiner, D.F.4    Pintar, J.E.5    Fricker, L.D.6
  • 39
    • 0036679173 scopus 로고    scopus 로고
    • Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects
    • Zhu X, Zhou A, Dey A, Norrbom C, Carroll R, Zhang C, et al. Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects. Proc Natl Acad Sci U S A 2002;99:10293-8.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 10293-10298
    • Zhu, X.1    Zhou, A.2    Dey, A.3    Norrbom, C.4    Carroll, R.5    Zhang, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.