The transmembrane domain of caveolin-1 exhibits a helix-break-helix structure

Biochimica et Biophysica Acta - Biomembranes

Volumn 1818, Issue 5, 2012, Pages 1158-1164

  Lee, Jinwoo ^a   Glover, Kerney Jebrell ^a  

^a LEHIGH UNIVERSITY   (United States)

Author keywords

Caveolae; Caveolin; Chemical shift indexing; Circular dichroism spectroscopy; Membrane protein; NMR spectroscopy

Indexed keywords

ALANINE; CAVEOLIN 1; DIMYRISTOYLPHOSPHATIDYLGLYCEROL; GLYCINE; ISOLEUCINE; PROLINE; VALINE;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ESCHERICHIA COLI; ISOTOPE LABELING; MICELLE; MOLECULAR PROBE; MUTAGENESIS; MUTATION RATE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PURIFICATION; RESIDUE ANALYSIS; STRUCTURE ANALYSIS;

AMINO ACID MOTIFS; AMINO ACID SUBSTITUTION; CAVEOLIN 1; CIRCULAR DICHROISM; HUMANS; MICELLES; MUTATION, MISSENSE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHOSPHATIDYLGLYCEROLS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 84862777817     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2011.12.033     Document Type: Article

References (30)

1. R.V. Stan Structure of caveolae Biochim. Biophys. Acta 1746 2005 334 348
2. T.M. Williams, and M.P. Lisanti The Caveolin genes: from cell biology to medicine Ann. Med. 36 2004 584 595
3. W.M. Krajewska, and I. Maslowska Caveolins: structure and function in signal transduction Cell. Mol. Biol. Lett. 9 2004 195 220
4. E. Spisni, V. Tomasi, A. Cestaro, and S.C. Tosatto Structural insights into the function of human caveolin 1 Biochem. Biophys. Res. Commun. 338 2005 1383 1390
5. M. Drab, P. Verkade, M. Elger, M. Kasper, M. Lohn, B. Lauterbach, J. Menne, C. Lindschau, F. Mende, F.C. Luft, A. Schedl, H. Haller, and T.V. Kurzchalia Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice Science 293 2001 2449 2452
6. G. Bonuccelli, M.C. Casimiro, F. Sotgia, C. Wang, M. Liu, S. Katiyar, J. Zhou, E. Dew, F. Capozza, K.M. Daumer, C. Minetti, J.N. Milliman, F. Alpy, M.C. Rio, C. Tomasetto, I. Mercier, N. Flomenberg, P.G. Frank, R.G. Pestell, and M.P. Lisanti Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature Am. J. Pathol. 174 2009 1650 1662
7. M. Shatz, and M. Liscovitch Caveolin-1: A tumor-promoting role in human cancer Int. J. Radiat. Biol. 84 2008 177 189
8. S.B. Gaudreault, D. Dea, and J. Poirier Increased caveolin-1 expression in Alzheimer's disease brain Neurobiol. Aging 25 2004 753 759
9. M. Ahn, H. Kim, Y. Matsumoto, and T. Shin Increased expression of caveolin-1 and-2 in the hearts of Lewis rats with experimental autoimmune myocarditis Autoimmunity 39 2006 489 495
10. N. Weiss, H. Couchoux, C. Legrand, C. Berthier, B. Allard, and V. Jacquemond Expression of the muscular dystrophy-associated caveolin-3(P104L) mutant in adult mouse skeletal muscle specifically alters the Ca(2+) channel function of the dihydropyridine receptor Pflugers Arch. 457 2008 361 375
11. U. Ortegren, M. Karlsson, N. Blazic, M. Blomqvist, F.H. Nystrom, J. Gustavsson, P. Fredman, and P. Stralfors Lipids and glycosphingolipids in caveolae and surrounding plasma membrane of primary rat adipocytes Eur. J. Biochem. 271 2004 2028 2036
12. S. Monier, R.G. Parton, F. Vogel, J. Behlke, A. Henske, and T.V. Kurzchalia VIP21-caveolin, a membrane protein constituent of the caveolar coat, oligomerizes in vivo and in vitro Mol. Biol. Cell 6 1995 911 927
13. P. Dupree, R.G. Parton, G. Raposo, T.V. Kurzchalia, and K. Simons Caveolae and sorting in the trans-Golgi network of epithelial cells EMBO J. 12 1993 1597 1605
14. R.G. Parton, M. Hanzal-Bayer, and J.F. Hancock Biogenesis of caveolae: a structural model for caveolin-induced domain formation J. Cell Sci. 119 2006 787 796
15. G.K. Voeltz, W.A. Prinz, Y. Shibata, J.M. Rist, and T.A. Rapoport A class of membrane proteins shaping the tubular endoplasmic reticulum Cell 124 2006 573 586
16. M. Decaffmeyer, Y.V. Shulga, A.O. Dicu, A. Thomas, R. Truant, M.K. Topham, R. Brasseur, and R.M. Epand Determination of the topology of the hydrophobic segment of mammalian diacylglycerol kinase epsilon in a cell membrane and its relationship to predictions from modeling J. Mol. Biol. 383 2008 797 809
17. S. Aoki, A. Thomas, M. Decaffmeyer, R. Brasseur, and R.M. Epand The role of proline in the membrane re-entrant helix of caveolin-1 J. Biol. Chem. 285 2010 33371 33380
18. C. Diefenderfer, J. Lee, S. Mlyanarski, Y. Guo, and K.J. Glover Reliable expression and purification of highly insoluble transmembrane domains Anal. Biochem. 384 2009 274 278
19. A. Uittenbogaard, and E.J. Smart Palmitoylation of caveolin-1 is required for cholesterol binding, chaperone complex formation, and rapid transport of cholesterol to caveolae J. Biol. Chem. 275 2000 25595 25599
20. D.J. Dietzen, W.R. Hastings, and D.M. Lublin Caveolin is palmitoylated on multiple cysteine residues. Palmitoylation is not necessary for localization of caveolin to caveolae J. Biol. Chem. 270 1995 6838 6842
21. F. Sotgia, B. Razani, G. Bonuccelli, W. Schubert, M. Battista, H. Lee, F. Capozza, A.L. Schubert, C. Minetti, J.T. Buckley, and M.P. Lisanti Intracellular retention of glycosylphosphatidyl inositol-linked proteins in caveolin-deficient cells Mol. Cell. Biol. 22 2002 3905 3926
22. J. Marley, M. Lu, and C. Bracken A method for efficient isotopic labeling of recombinant proteins RID A-7811-2009 J. Biomol. NMR 20 2001 71 75
23. S.M. Truhlar, C.F. Cervantes, J.W. Torpey, M. Kjaergaard, and E.A. Komives Rapid mass spectrometric analysis of 15N-Leu incorporation fidelity during preparation of specifically labeled NMR samples Protein Sci. 17 2008 1636 1639
24. F. Delaglio, S. Grzesiek, G.W. Vuister, G. Zhu, J. Pfeifer, and A. Bax NMRPipe: a multidimensional spectral processing system based on UNIX pipes J. Biomol. NMR 6 1995 277 293
25. T.D. Goddard, D.G. Kneller, SPARKY 3, University of California, San Francisco.
26. L. Whitmore, and B. Wallace DICHROWEB, an online server for protein secondary structure analyses from circular dichroism spectroscopic data RID C-5651-2008 RID C-3753-2008 Nucleic Acids Res. 32 2004 W668 W673
27. A. Lobley, L. Whitmore, and B. Wallace DICHROWEB: an interactive website for the analysis of protein secondary structure from circular dichroism spectra RID C-5651-2008 RID C-3753-2008 Bioinformatics 18 2002 211 212
28. C.R. Sanders, and F. Sonnichsen Solution NMR of membrane proteins: practice and challenges Magn. Reson. Chem. 44 2006 S24 S40 Spec No
29. D. Wishart, and B. Sykes The C-13 Chemical-Shift Index - a Simple Method for the Identification of Protein Secondary Structure using C-13 Chemical-Shift Data J. Biomol. NMR 4 1994 171 180
30. S. Aoki, A. Thomas, M. Decaffmeyer, R. Brasseur, and R.M. Epand The role of proline in the membrane re-entrant helix of caveolin-1 J. Biol. Chem. 285 2010 33371 33380