Biomimetic tubular nanofiber mesh and platelet rich plasma-mediated delivery of BMP-7 for large bone defect regeneration

Cell and Tissue Research

Volumn 347, Issue 3, 2012, Pages 603-612

  Berner, A ^a,b   Boerckel, J D ^c   Saifzadeh, S ^a   Steck, R ^a   Ren, J ^a   Vaquette, C ^a   Zhang, J Qiyi ^a   Nerlich, M ^b   Guldberg, R E ^c   Hutmacher, D W ^a,c   Woodruff, M A ^a  

^a QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^b UNIVERSITY OF REGENSBURG   (Germany)

^c GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Bone defect; Bone morphogenetic protein; Bone tissue engineering; Growth factors; Nanofiber mesh

Indexed keywords

CALCIUM PHOSPHATE; NANOFIBER; NANOMESH; OSTEOGENIC PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BIOMECHANICS; BIOMIMETICS; BONE DEFECT; BONE MASS; BONE RADIOGRAPHY; BONE REGENERATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFECT; HISTOPATHOLOGY; MALE; MATERIAL COATING; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; OSSIFICATION; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RAT; REVIEW; THROMBOCYTE RICH PLASMA; TISSUE ENGINEERING;

ANIMALS; BIOMECHANICS; BIOMIMETIC MATERIALS; BONE AND BONES; BONE MORPHOGENETIC PROTEIN 7; BONE REGENERATION; DRUG DELIVERY SYSTEMS; IMAGING, THREE-DIMENSIONAL; MALE; NANOFIBERS; OSSEOINTEGRATION; PLATELET-RICH PLASMA; RATS; RATS, INBRED LEW; TISSUE SCAFFOLDS; TORQUE; X-RAY MICROTOMOGRAPHY;

ANIMALIA; RATTUS;

EID: 84862777217     PISSN: 0302766X     EISSN: 14320878     Source Type: Journal    
DOI: 10.1007/s00441-011-1298-z     Document Type: Review

References (31)

1. Boerckel JD, Kolambkar YM, Dupont KM, Uhrig BA, Phelps EA, Stevens HY, Garcia AJ, Guldberg RE (2011) Effects of protein dose and delivery system on BMP-mediated bone regeneration. Biomaterials 32:5241-5251
2. Davies JE, Matta R, Mendes VC, Perri de Carvalho PS (2010) Development, characterization and clinical use of a biodegradable composite scaffold for bone engineering in oro-maxillo-facial surgery. Organogenesis 6:161-166
3. De Biase P, Capanna R (2005) Clinical applications of BMPs. Injury 36(Suppl 3):S43-S46
4. Ekholm E, Tommila M, Forsback AP, Martson M, Holmbom J, Aaritalo V, Finnberg C, Kuusilehto A, Salonen J, Yli-Urpo A et al (2005) Hydroxyapatite coating of cellulose sponge does not improve its osteogenic potency in rat bone. Acta Biomater 1:535-544 (Pubitemid 43348768)
5. Fontana F, Rocchietta I, Addis A, Schupbach P, Zanotti G, Simion M (2011) Effects of a calcium phosphate coating on the osseointegration of endosseous implants in a rabbit model. Clin Oral Implants Res 22:760-766
6. Friedlaender GE, Perry CR, Cole JD, Cook SD, Cierny G, Muschler GF, Zych GA, Calhoun JH, LaForte AJ, Yin S (2001) Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions. J Bone Joint Surg Am 83(Suppl 1):S151-S158
7. Garrison KR, Donell S, Ryder J, Shemilt I, Mugford M, Harvey I, Song F (2007). Clinical effectiveness and cost-effectiveness of bone morphogenetic proteins in the non-healing of fractures andspinal fusion: a systematic review. Health Technol Assess 11:1-150, iii-iv
8. Govender S, Csimma C, Genant HK, Valentin-Opran A, Amit Y, Arbel R, Aro H, Atar D, Bishay M, Borner MG et al (2002) Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: a prospective, controlled, randomized study of four hundred and fifty patients. J Bone Joint Surg Am 84:2123-2134 (Pubitemid 35417689)
9. Heckman JD, Boyan BD, Aufdemorte TB, Abbott JT (1991) The use of bone morphogenetic protein in the treatment of non-union in a canine model. J Bone Joint Surg Am 73:750-764
10. Heckman JD, Ehler W, Brooks BP, Aufdemorte TB, Lohmann CH, Morgan T, Boyan BD (1999) Bone morphogenetic protein but not transforming growth factor-beta enhances bone formation in canine diaphyseal nonunions implanted with a biodegradable composite polymer. J Bone Joint Surg Am 81:1717-1729
11. Hildner F, Albrecht C, Gabriel C, Redl H, van Griensven M (2011) State of the art and future perspectives of articular cartilage regeneration: a focus on adipose-derived stem cells and platelet-derived products. J Tissue Eng Regen Med 5:e36-e51
12. Johnson EE, Urist MR (1989) Distal metaphyseal tibial nonunions associated with significant bowing deformity and cortical bone loss: treatment with human bone morphogenetic protein (h-BMP) and internal fixation. Nippon Seikeigeka Gakkai Zasshi 63:613-620
13. Johnson EE, Urist MR, Finerman GA (1990). Distal metaphyseal tibial nonunion. Deformity and bone loss treated by open reduction, internal fixation, and human bone morphogenetic protein (hBMP). Clin Orthop Relat Res :234-240 (Pubitemid 20033989)
14. Kloen P, Doty SB, Gordon E, Rubel IF, Goumans MJ, Helfet DL (2002) Expression and activation of the BMP-signaling components in human fracture nonunions. J Bone Joint Surg Am 84:1909-1918 (Pubitemid 35283352)
15. Kolambkar YM, Dupont KM, Boerckel JD, Huebsch N, Mooney DJ, Hutmacher DW, Guldberg RE (2011) An alginate-based hybrid system for growth factor delivery in the functional repair of large bone defects. Biomaterials 32:65-74
16. Kretlow JD, Mikos AG (2007) Review: mineralization of synthetic polymer scaffolds for bone tissue engineering. Tissue Eng 13:927-938 (Pubitemid 46870417)
17. Lee KS, Wilson JJ, Rabago DP, Baer GS, Jacobson JA, Borrero CG (2011) Musculoskeletal applications of platelet-rich plasma: fad or future? AJR Am J Roentgenol 196:628-636
18. Liu W, Yeh YC, Lipner J, Xie J, Sung HW, Thomopoulos S, Xia Y (2011) Enhancing the stiffness of electrospun nanofiber scaffolds with a controlled surface coating and mineralization. Langmuir 27 (15):9088-9093
19. Mihalko WM, Howard C, Dimaano F, Dimaano N, Hawkins M (2010) Effects of hydroxyapatite on titanium foam as a bone ingrowth surface in acetabular shells: a canine study. J Long Term Eff Med Implants 20:35-42
20. Oest ME, Dupont KM, Kong HJ, Mooney DJ, Guldberg RE (2007) Quantitative assessment of scaffold and growth factor-mediated repair of critically sized bone defects. J Orthop Res 25:941-950 (Pubitemid 47046441)
21. Ozkaynak E, Rueger DC, Drier EA, Corbett C, Ridge RJ, Sampath TK, Oppermann H (1990) OP-1 cDNA encodes an osteogenic protein in the TGF-beta family. EMBO J 9:2085-2093
22. Pazzaglia UE, Zatti G, Ragni P, Ceciliani L (1988) The role of mineralization in experimental models of osteogenetic induction with decalcified bone matrix. Ital J Orthop Traumatol 14:369-375 (Pubitemid 19095837)
23. Perry CR (1999) Bone repair techniques, bone graft, and bone graft substitutes. Clin Orthop Relat Res 360:71-86
24. Redler LH, Thompson SA, Hsu SH, Ahmad CS, Levine WN (2011) Platelet-rich plasma therapy: a systematic literature review and evidence for clinical use. Phys Sportsmed 39:42-51
25. Reichert JC, Woodruff MA, Friis T, Quent VM, Gronthos S, Duda GN, Schutz MA, Hutmacher DW (2010) Ovine bone- and marrow-derived progenitor cells and their potential for scaffold-based bone tissue engineering applications in vitro and in vivo. J Tissue Eng Regen Med 4:565-576
26. Shields LB, Raque GH, Glassman SD, Campbell M, Vitaz T, Harpring J, Shields CB (2006) Adverse effects associated with high-dose recombinant human bone morphogenetic protein-2 use in anterior cervical spine fusion. Spine (Phila Pa 1976) 31:542-547
27. Urist MR (1965) Bone: formation by autoinduction. Science 150:893-899
28. Weibrich G, Kleis WK, Kunz-Kostomanolakis M, Loos AH, Wagner W (2001) Correlation of platelet concentration in platelet-rich plasma to the extraction method, age, sex, and platelet count of the donor. Int J Oral Maxillofac Implants 16:693-699 (Pubitemid 33674670)
29. Weiner S, Wagner HD (1998) The material bone: structure mechanical function relations. Annu Rev Mater Sci 28:271-298 (Pubitemid 128631421)
30. Xiao C, Zhou H, Liu G, Zhang P, Fu Y, Gu P, Hou H, Tang T, Fan X (2011) Bone marrow stromal cells with a combined expression of BMP-2 and VEGF-165 enhanced bone regeneration. Biomed Mater 6:015013
31. Yang F, Wolke JGC, Jansen JA (2008) Biomimetic calcium phosphate coating on electrospun poly (epsilon-caprolactone) scaffolds for bone tissue engineering. Chem Eng J 137:154-161 (Pubitemid 351226629)