메뉴 건너뛰기




Volumn 126, Issue 1, 2012, Pages 41-46

Sequential bevacizumab and oral cyclophosphamide for recurrent ovarian cancer

Author keywords

Anti angiogenic agents; Bevacizumab; Metronomic therapy; Ovarian cancer

Indexed keywords

BEVACIZUMAB; CYCLOPHOSPHAMIDE;

EID: 84862765843     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2012.04.003     Document Type: Article
Times cited : (14)

References (34)
  • 2
    • 63049115790 scopus 로고    scopus 로고
    • Evaluation of new platinum-based treatment regimens in advanced-stage ovarian cancer: A Phase III Trial of the Gynecologic Cancer Intergroup
    • Bookman MA, Brady MF, McGuire WP, Harper PG, Alberts DS, Friedlander M, et al. Evaluation of new platinum-based treatment regimens in advanced-stage ovarian cancer: a Phase III Trial of the Gynecologic Cancer Intergroup. J Clin Oncol 2009;27(9):1419-25.
    • (2009) J Clin Oncol , vol.27 , Issue.9 , pp. 1419-1425
    • Bookman, M.A.1    Brady, M.F.2    McGuire, W.P.3    Harper, P.G.4    Alberts, D.S.5    Friedlander, M.6
  • 3
    • 4143087249 scopus 로고    scopus 로고
    • Duration of response to second-line, platinum-based chemotherapy for ovarian cancer: Implications for patient management and clinical trial design
    • DOI 10.1200/JCO.2004.05.195
    • Markman M, Markman J, Webster K, Zanotti K, Kulp B, Peterson G, et al. Duration of response to second-line, platinum-based chemotherapy for ovarian cancer: implications for patient management and clinical trial design. J Clin Oncol 2004;22:3120-5. (Pubitemid 41103725)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.15 , pp. 3120-3125
    • Markman, M.1    Markman, J.2    Webster, K.3    Zanotti, K.4    Kulp, B.5    Peterson, G.6    Belinson, J.7
  • 5
    • 0035879099 scopus 로고    scopus 로고
    • Recurrent epithelial ovarian carcinoma: A randomized phase III study of pegylated liposomal doxorubicin versus topotecan
    • Gordon AN, Fleagle JT, Guthrie D, Parkin DE, Gore ME, Lacave AJ, et al. Recurrent epithelial ovarian carcinoma: a randomized phase III study of pegylated liposomal doxorubicin versus topotecan. J Clin Oncol 2001 Jul 15;19(14):3312-22. (Pubitemid 32642183)
    • (2001) Journal of Clinical Oncology , vol.19 , Issue.14 , pp. 3312-3322
    • Gordon, A.N.1    Fleagle, J.T.2    Guthrie, D.3    Parkin, D.E.4    Gore, M.E.5    Lacave, A.J.6
  • 6
    • 34447499062 scopus 로고    scopus 로고
    • Novel approaches in advancing the treatment of epithelial ovarian cancer: The role of angiogenesis inhibition
    • DOI 10.1200/JCO.2007.11.1088
    • Martin L, Schilder R. Novel approaches in advancing the treatment of epithelial ovarian cancer: the role of angiogenesis inhibition. J Clin Oncol 2007;25:2894-901. (Pubitemid 47123153)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.20 , pp. 2894-2901
    • Martin, L.1    Schilder, R.2
  • 7
    • 36849019301 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: A Gynecologic Oncology Group study
    • DOI 10.1200/JCO.2007.11.5345
    • Burger RA, Sill MW, Monk BJ, Greer BE, Sorosky JI. Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: a Gynecologic Oncology Group Study. J Clin Oncol 2007;25:5165-71. (Pubitemid 350237599)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.33 , pp. 5165-5171
    • Burger, R.A.1    Sill, M.W.2    Monk, B.J.3    Greer, B.E.4    Sorosky, J.I.5
  • 9
    • 84855425106 scopus 로고    scopus 로고
    • Incorporation of bevacizumab in the primary treatment of ovarian cancer
    • Dec 29
    • Burger RA, Brady MF, Bookman MA, Fleming GF, Monk BJ, Huang H, et al. Incorporation of bevacizumab in the primary treatment of ovarian cancer. N Engl J Med 2011 Dec 29;365(26):2473-83.
    • (2011) N Engl J Med , vol.365 , Issue.26 , pp. 2473-2483
    • Burger, R.A.1    Brady, M.F.2    Bookman, M.A.3    Fleming, G.F.4    Monk, B.J.5    Huang, H.6
  • 10
    • 73949123481 scopus 로고    scopus 로고
    • Cediranib, an oral inhibitor of vascular endothelial growth factor receptor kinases, is an active drug in recurrent epithelial ovarian, fallopian tube, and peritoneal cancer
    • Matulonis UA, Berlin S, Ivy P, Tyburski K, Krasner C, Zarwan C, et al. Cediranib, an oral inhibitor of vascular endothelial growth factor receptor kinases, is an active drug in recurrent epithelial ovarian, fallopian tube, and peritoneal cancer. J Clin Oncol 2009;27:5601-6.
    • (2009) J Clin Oncol , vol.27 , pp. 5601-5606
    • Matulonis, U.A.1    Berlin, S.2    Ivy, P.3    Tyburski, K.4    Krasner, C.5    Zarwan, C.6
  • 11
    • 79951988792 scopus 로고    scopus 로고
    • Activity of sorafenib in recurrent ovarian cancer and primary peritoneal carcinomatosis: A gynecologic oncology group trial
    • Matel D, Sill MW, Lankes HA, DeGeest K, Bristow RE, Mutch D, et al. Activity of sorafenib in recurrent ovarian cancer and primary peritoneal carcinomatosis: a gynecologic oncology group trial. J Clin Oncol 2011;29(1):69-75.
    • (2011) J Clin Oncol , vol.29 , Issue.1 , pp. 69-75
    • Matel, D.1    Sill, M.W.2    Lankes, H.A.3    DeGeest, K.4    Bristow, R.E.5    Mutch, D.6
  • 12
    • 79251585977 scopus 로고    scopus 로고
    • A phase II study of sunitinib in patients with recurrent epithelial ovarian and primary peritoneal carcinoma: An NCIC Clinical Trials Group Study
    • Biagi JJ, Oza AM, Chalchal HI, Grimshaw R, Ellard SL, Lee U, et al. A phase II study of sunitinib in patients with recurrent epithelial ovarian and primary peritoneal carcinoma: an NCIC Clinical Trials Group Study. Ann Oncol 2011;22:335-40.
    • (2011) Ann Oncol , vol.22 , pp. 335-340
    • Biagi, J.J.1    Oza, A.M.2    Chalchal, H.I.3    Grimshaw, R.4    Ellard, S.L.5    Lee, U.6
  • 16
    • 80053561888 scopus 로고    scopus 로고
    • Randomized phase II placebo-controlled trial of maintenance therapy using the oral triple angiokinase inhibitor BIBF 1120 after chemotherapy for relapsed ovarian cancer
    • Ledermann JA, Hackshaw A, Kaye S, Jayson G, Gabra H, McNeish I, et al. Randomized phase II placebo-controlled trial of maintenance therapy using the oral triple angiokinase inhibitor BIBF 1120 after chemotherapy for relapsed ovarian cancer. J Clin Oncol 2011;29:3798-804.
    • (2011) J Clin Oncol , vol.29 , pp. 3798-3804
    • Ledermann, J.A.1    Hackshaw, A.2    Kaye, S.3    Jayson, G.4    Gabra, H.5    McNeish, I.6
  • 17
    • 2942615257 scopus 로고    scopus 로고
    • The anti-angiogenic basis of metronomic chemotherapy
    • Kerbel RS, Kamen BA. The anti-angiogenic basis of metronomic chemotherapy. Nat Rev Cancer 2004;4:423-36. (Pubitemid 38745528)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.6 , pp. 423-436
    • Kerbel, R.S.1    Kamen, B.A.2
  • 18
    • 67349094407 scopus 로고    scopus 로고
    • Improving conventional or low dose metronomic chemotherapy with targeted antiangiogenic drugs
    • Kerbel RS. Improving conventional or low dose metronomic chemotherapy with targeted antiangiogenic drugs. Cancer Res Treat 2007;39:150-9.
    • (2007) Cancer Res Treat , vol.39 , pp. 150-159
    • Kerbel, R.S.1
  • 19
    • 0034048358 scopus 로고    scopus 로고
    • Less is, more, regularly: Metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice
    • Hanahan D, Bergers G, Bergland E. Less is more, regularly: metronomic dosing of cytotoxic drugs can target angiogenesis in mice. J Clin Invest 2000;105:1045-7. (Pubitemid 30217688)
    • (2000) Journal of Clinical Investigation , vol.105 , Issue.8 , pp. 1045-1047
    • Hanahan, D.1    Bergers, G.2    Bergsland, E.3
  • 22
    • 80053229517 scopus 로고    scopus 로고
    • OCEANS: A randomized, double-blinded, placebo-controlled phase III trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent epithelial ovarian, primary peritoneal, or fallopian tube cancer
    • abstr LBA5007
    • Aghajanian C, Finkler NJ, Rutherford T, Smith DA, Yi J, Parmar H, et al. OCEANS: a randomized, double-blinded, placebo-controlled phase III trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent epithelial ovarian, primary peritoneal, or fallopian tube cancer. J Clin Oncol 2011;29 (Suppl.; abstr LBA5007).
    • (2011) J Clin Oncol , vol.29 , Issue.SUPPL.
    • Aghajanian, C.1    Finkler, N.J.2    Rutherford, T.3    Smith, D.A.4    Yi, J.5    Parmar, H.6
  • 24
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors
    • European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, Rubenstein L, et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. JNCI 2000;92:205-16.
    • (2000) JNCI , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3    Wanders, J.4    Kaplan, R.S.5    Rubenstein, L.6
  • 25
    • 37849035249 scopus 로고    scopus 로고
    • Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: A Trial of the California, Chicago, and Princess Margaret Hospital Phase II consortia
    • Garcia AA, Hirte H, Fleming G, Yang D, Tsao-Wei DD, Roman L, et al. Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: a Trial of the California, Chicago, and Princess Margaret Hospital Phase II consortia. J Clin Oncol 2008;26:76-82.
    • (2008) J Clin Oncol , vol.26 , pp. 76-82
    • Garcia, A.A.1    Hirte, H.2    Fleming, G.3    Yang, D.4    Tsao-Wei, D.D.5    Roman, L.6
  • 26
    • 56749169353 scopus 로고    scopus 로고
    • Bevacizumab beyond first progression is associated with prolonged overall survival in metastatic colorectal cancer: Results from a large observational cohort study (BRiTE)
    • Grothey A, Sugrue MM, Purdie DM, Dong W, Sargent D, Hedrick E, et al. Bevacizumab beyond first progression is associated with prolonged overall survival in metastatic colorectal cancer: results from a large observational cohort study (BRiTE). J Clin Oncol 2008;26:5326-34.
    • (2008) J Clin Oncol , vol.26 , pp. 5326-5334
    • Grothey, A.1    Sugrue, M.M.2    Purdie, D.M.3    Dong, W.4    Sargent, D.5    Hedrick, E.6
  • 27
    • 35348904080 scopus 로고    scopus 로고
    • Bevacizumab plus cyclophosphamide in heavily pretreated patients with recurrent ovarian cancer
    • DOI 10.1016/j.ygyno.2007.07.017, PII S0090825807004635
    • Chura JC, Van Iseghem K, Downs LS, Carson LF, Judson PL. Bevacizumab plus cyclophosphamide in heavily pretreated patients with recurrent ovarian cancer. Gynecol Oncol 2007;107:326-30. (Pubitemid 47575735)
    • (2007) Gynecologic Oncology , vol.107 , Issue.2 , pp. 326-330
    • Chura, J.C.1    Van Iseghem, K.2    Downs Jr., L.S.3    Carson, L.F.4    Judson, P.L.5
  • 28
    • 78149360957 scopus 로고    scopus 로고
    • Feasibility study of oral cyclophosphamide salvage therapy for the treatment of heavily pretreated patients with recurrent epithelial cancer
    • Watanabe Y, Etoh T, Koike E, Mizuno Y, Wang WM, Hoshiai H, et al. Feasibility study of oral cyclophosphamide salvage therapy for the treatment of heavily pretreated patients with recurrent epithelial cancer. Int J Clin Oncol 2010;15:468-71.
    • (2010) Int J Clin Oncol , vol.15 , pp. 468-471
    • Watanabe, Y.1    Etoh, T.2    Koike, E.3    Mizuno, Y.4    Wang, W.M.5    Hoshiai, H.6
  • 29
    • 34248198313 scopus 로고    scopus 로고
    • Cyclophosphamide "metronomic" chemotherapy for palliative treatment of a young patient with advanced epithelial ovarian cancer
    • Samaritani R, Corrado G, Vizza E, Sbiroli C. Cyclophosphamide "metronomic" chemotherapy for palliative treatment of a young patient with advanced epithelial ovarian cancer. BMC Cancer 2007;15(7):65.
    • (2007) BMC Cancer , vol.15 , Issue.7 , pp. 65
    • Samaritani, R.1    Corrado, G.2    Vizza, E.3    Sbiroli, C.4
  • 30
    • 80054688412 scopus 로고    scopus 로고
    • The PACOVAR-trial: A phase I/II study of pazopanib (GW786034) and cyclophosphamide in patients with platinum-resistant recurrent, pre-treated ovarian cancer
    • Eichbaum M, Mayer C, Eichhoff R, Bischofs E, Gebauer G, Fehm T, et al. The PACOVAR-trial: a phase I/II study of pazopanib (GW786034) and cyclophosphamide in patients with platinum-resistant recurrent, pre-treated ovarian cancer. BMC Cancer 2011;11:453.
    • (2011) BMC Cancer , vol.11 , pp. 453
    • Eichbaum, M.1    Mayer, C.2    Eichhoff, R.3    Bischofs, E.4    Gebauer, G.5    Fehm, T.6
  • 31
    • 49249113484 scopus 로고    scopus 로고
    • Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity
    • Azad NS, Posadas EM, Kwitkowski VE, Steinberg SM, Jain L, Annunziata CM, et al. Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity. J Clin Oncology 2008;26:3709-14.
    • (2008) J Clin Oncology , vol.26 , pp. 3709-3714
    • Azad, N.S.1    Posadas, E.M.2    Kwitkowski, V.E.3    Steinberg, S.M.4    Jain, L.5    Annunziata, C.M.6
  • 32
    • 33744973643 scopus 로고    scopus 로고
    • Metronomic chemotherapy with and without bevacizumab for advanced breast cancer: A randomized phase II study
    • abstract 4
    • Burstein HJ, Spigel D, Kinds Vogel K, Vogel K, Parker LM, Bunnell CA, et al. Metronomic chemotherapy with and without bevacizumab for advanced breast cancer: a randomized phase II study. Breast Cancer Res Treat 2005;92(1 s) (Suppl. abstract 4).
    • (2005) Breast Cancer Res Treat , vol.92 , Issue.1 S SUPPL.
    • Burstein, H.J.1    Spigel, D.2    Kinds Vogel, K.3    Vogel, K.4    Parker, L.M.5    Bunnell, C.A.6
  • 33
    • 77950811722 scopus 로고    scopus 로고
    • Bridging the gap between cytotoxic and biologic therapy with metronomic topotecan and pazopanib in ovarian cancer
    • Merritt WM, Nick AM, Carroll AR, Lu C, Matsuo K, Dumble M, et al. Bridging the gap between cytotoxic and biologic therapy with metronomic topotecan and pazopanib in ovarian cancer. Mol Cancer Ther 2010;9:985-95.
    • (2010) Mol Cancer Ther , vol.9 , pp. 985-995
    • Merritt, W.M.1    Nick, A.M.2    Carroll, A.R.3    Lu, C.4    Matsuo, K.5    Dumble, M.6
  • 34
    • 77950815444 scopus 로고    scopus 로고
    • Potent preclinical impact of metronomic low-dose oral topotecan combined with the antiangiogenic drug pazopanib for the treatment of ovarian cancer
    • Hashimoto K, Man S, Xu P, Cruz-Munoz W, Tang T, Kumar R, et al. Potent preclinical impact of metronomic low-dose oral topotecan combined with the antiangiogenic drug pazopanib for the treatment of ovarian cancer. Mol Cancer Ther 2010;9:996-1006.
    • (2010) Mol Cancer Ther , vol.9 , pp. 996-1006
    • Hashimoto, K.1    Man, S.2    Xu, P.3    Cruz-Munoz, W.4    Tang, T.5    Kumar, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.