Performance of methods for handling missing categorical covariate data in population pharmacokinetic analyses

AAPS Journal

Volumn 14, Issue 3, 2012, Pages 601-611

  Keizer, Ron J ^a,b,d   Zandvliet, Anthe S ^a,b   Beijnen, Jos H ^a,b,c   Schellens, Jan H M ^b,c   Huitema, Alwin D R ^a,b  

^a SLOTERVAART HOSPITAL   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

^d UPPSALA UNIVERSITY   (Sweden)

Author keywords

categorical data; covariates; missing data; pharmacokinetics; pharmacometrics

Indexed keywords

EFAVIRENZ; NEVIRAPINE;

ADDITIONAL EFFECT PARAMETER FOR THE GROUP MISSING DATA; ARTICLE; DISCARDING DATA; DRUG BLOOD LEVEL; HUMAN; INFORMATION; INFORMATION PROCESSING; METHODOLOGY; MISSING AT RANDOM; MISSING CATEGORICAL DATA; MISSING COMPLETELEY AT RANDOM; MISSING NOT AT RANDOM; MIXTURE METHOD; PHARMACOKINETICS; POPULATION PHARMACOKINETICS; SIMULATION;

LIKELIHOOD FUNCTIONS; PHARMACOKINETICS;

EID: 84862765338     PISSN: 15507416     EISSN: None     Source Type: Journal    
DOI: 10.1208/s12248-012-9373-2     Document Type: Article

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