Cytogenetic profile of 1,863 Ph/BCR-ABL-positive chronic myelogenous leukemia patients from the Chinese population

Annals of Hematology

Volumn 91, Issue 7, 2012, Pages 1065-1072

  Mu, Qitian ^a,b   Ma, Qiuling ^a,c   Wang, Yungui ^a   Chen, Zhimei ^a   Tong, Xiangmin ^a   Chen, Fei Fei ^a   Lu, Ying ^b   Jin, Jie ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b NINGBO FIRST HOSPITAL   (China)

^c HENAN UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Additional chromosome abnormalities; Blast crisis; Chronic myelogenous leukemia; Cytogenetics; Variant Ph translocation

Indexed keywords

ALPHA INTERFERON; BCR ABL PROTEIN; HYDROXYUREA; PROTEIN TYROSINE KINASE INHIBITOR;

ADULT; ARTICLE; BLAST CELL CRISIS; BONE MARROW CELL; CANCER GROWTH; CELL DIFFERENTIATION; CHINA; CHINESE; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME TRANSLOCATION; CHRONIC MYELOID LEUKEMIA; CYTOGENETICS; FEMALE; GRANULOCYTE; HUMAN; INCIDENCE; KARYOTYPE; MAJOR CLINICAL STUDY; MALE; MONOCYTE; MONOSOMY 7; PHILADELPHIA 1 CHROMOSOME; PREVALENCE; PRIORITY JOURNAL; SAMPLE SIZE; TRISOMY 8;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ASIAN CONTINENTAL ANCESTRY GROUP; CHILD; CHILD, PRESCHOOL; CHINA; CYTOGENETIC ANALYSIS; FEMALE; GENETICS, POPULATION; HUMANS; INCIDENCE; INFANT; KARYOTYPE; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MALE; MIDDLE AGED; YOUNG ADULT;

EID: 84862763893     PISSN: 09395555     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-012-1421-6     Document Type: Article

References (41)

1. A Quintas-Cardama JE Cortes 2006 Chronic myeloid leukemia: diagnosis and treatment Mayo Clin Proc 81 973 988 16835977 10.4065/81.7.973 1:CAS:528:DC%2BD28Xntlanu7Y%3D
2. Y Benneriah GQ Daley AM Mesmasson ON Witte D Baltimore 1986 The chronic myelogenous leukemia specific P210-protein is the product of the Bcr/Abl hybrid gene Science 233 212 214 10.1126/science.3460176 1:CAS:528:DyaL28XkvFagtrs%3D
3. JW Voncken V Kaartinen PK Pattengale WTV Germeraad J Groffen N Heisterkamp 1995 Bcr/Abl P210 and P190 cause distinct leukemia in transgenic mice Blood 86 4603 4611 8541551 1:CAS:528:DyaK2MXpvFCjs7g%3D
4. B Calabretta D Perrotti 2004 The biology of CML blast crisis Blood 103 4010 4022 14982876 10.1182/blood-2003-12-4111 1:CAS:528:DC%2BD2cXkvVyisb8%3D
5. HJ Ch'ang HF Tien CH Wang, et al. 1993 Comparison of clinical and biologic features between myeloid and lymphoid transformation of Philadelphia chromosome positive chronic myeloid leukemia Cancer Genet Cytogenet 71 87 93 8275458 10.1016/0165-4608(93)90206-2
6. M Krulik N Smadja A Degramont, et al. 1987 Sequential karyotype study on Ph-positive chronic myelocytic-leukemia-significance of additional chromosomal-abnormalities during disease evolution Cancer 60 974 979 3475159 10.1002/1097-0142(19870901)60:5<974::AID-CNCR2820600510>3.0.CO;2-1 1:STN:280:DyaL2s3ntlWhtw%3D%3D
7. K Michalova J Musilova Z Koudelova J Placerova L Matuchova 1988 Cytogenetic study of chronic myeloid leukemia Neoplasma 35 571 581 3216931 1:STN:280:DyaL1M7ht1CjtA%3D%3D
8. AG Reid VA De Melo K Elderfield, et al. 2009 Phenotype of blasts in chronic myeloid leukemia in blastic phase-analysis of bone marrow trephine biopsies and correlation with cytogenetics Leuk Res 33 418 425 18760473 10.1016/j.leukres.2008.07.019
9. L Parreira L Kearney F Rassool, et al. 1986 Correlation between chromosomal-abnormalities and blast phenotype in the blast crisis of Ph-positive Cgl Cancer Genet Cytogenet 22 29 34 3456827 10.1016/0165-4608(86)90134-2 1:STN:280:DyaL287mtFChtA%3D%3D
10. E Lippert G Etienne MJ Mozziconacci, et al. 2010 Loss of the Y chromosome in Philadelphia-positive cells predicts a poor response of chronic myeloid leukemia patients to imatinib mesylate therapy Haematologica 95 1604 1607 20435623 10.3324/haematol.2009.019109 1:CAS:528:DC%2BC38Xns1Giuw%3D%3D
11. Y Cheng Y Wang H Wang, et al. 2009 Cytogenetic profile of de novo acute myeloid leukemia: a study based on 1432 patients in a single institution of China Leukemia 23 1801 1806 19474801 10.1038/leu.2009.107 1:STN:280: DC%2BD1Mnos1yrug%3D%3D
12. PC Nowell DA Hungerford 1960 A minute chromosome in human chronic granulocytic leukemia Science 132 1497
13. JD Rowley 1973 New consistent chromosomal abnormality in chronic myelogenous leukemia identified by quinacrine fluorescence and Giemsa staining Nature 243 290 293 4126434 10.1038/243290a0 1:STN:280:DyaE2c%2Fgs1eksw%3D%3D
14. M Rohrbacher J Hasford 2009 Epidemiology of chronic myeloid leukaemia (CML) Best Pract Res Clin Haematol 22 295 302 19959081 10.1016/j.beha.2009.07. 007
15. M Rohrbacher U Berger A Hochhaus, et al. 2009 Clinical trials underestimate the age of chronic myeloid leukemia (CML) patients. Incidence and median age of Ph/BCR-ABL-positive CML and other chronic myeloproliferative disorders in a representative area in Germany Leukemia 23 602 604 18784744 10.1038/leu.2008.245 1:STN:280:DC%2BD1M7pvVSqsQ%3D%3D
16. S Tardieu C Brun-Strang P Berthaud, et al. 2005 Management of chronic myeloid leukemia in France: a multicentered cross-sectional study on 538 patients Pharmacoepidemiol Drug Saf 14 545 553 15534856 10.1002/pds.1046
17. WY Au PB Caguioa C Chuah, et al. 2009 Chronic myeloid leukemia in Asia Int J Hematol 89 14 23 19101781 10.1007/s12185-008-0230-0
18. HH Weng SS Tsai HF Chiu TN Wu CY Yang 2008 Association of childhood leukemia with residential exposure to petrochemical air pollution in Taiwan Inhal Toxico 2 31 36 10.1080/08958370701758734
19. CL Yu SF Wang PC Pan, et al. 2009 Residential exposure to petrochemicals and the risk of leukemia: using geographic information system tools to estimate individual-level residential exposure Am J Epidemiol 164 200 207 10.1093/aje/kwj182
20. CM Wong N Vichit-Vadakan H Kan Z Qian 2008 Public Health and Air Pollution in Asia (PAPA): a multicity study of short-term effects of air pollution on mortality Environ Health Perspect 116 1195 1202 18795163 10.1289/ehp.11257 1:CAS:528:DC%2BD1cXhtFOis7fN
21. A Bennour H Sennana MA Laatiri M Elloumi A Khelif A Saad 2009 Molecular cytogenetic characterization of variant Philadelphia translocations in chronic myeloid leukemia: genesis and deletion of derivative chromosome 9 Cancer Genet Cytogenet 194 30 37 19737651 10.1016/j.cancergencyto.2009.05.010 1:CAS:528:DC%2BD1MXhtV2ks7nM
22. B Lowenberg A Hagemeijer J Abels 1985 Detection of the blastic crisis cell clone in chronic myeloid-leukemia Br J Haematol 59 27 36 3855648 10.1111/j.1365-2141.1985.tb02960.x 1:STN:280:DyaL2M7it1Giuw%3D%3D
23. F Mitelman 1993 The cytogenetic scenario of chronic myeloid leukemia Leuk Lymphoma 11 Suppl 1 11 15 8251885 10.3109/10428199309047856
24. HM Kantarjian MJ Keating M Talpaz, et al. 1987 Chronic myelogenous leukemia in blast crisis. Analysis of 242 patients Am J Med 83 445 454 3477958 10.1016/0002-9343(87)90754-6 1:STN:280:DyaL1c%2FitFSlsQ%3D%3D
25. A Quintas-Cardama J Cortes 2009 Molecular biology of bcr-abl1-positive chronic myeloid leukemia Blood 113 1619 1630 18827185 10.1182/blood-2008-03- 144790 1:CAS:528:DC%2BD1MXisV2iurs%3D
26. CC Yin J Cortes B Barkoh K Hayes H Kantarjian D Jones 2006 t(3;21)(q26;q22) in myeloid leukemia: an aggressive syndrome of blast transformation associated with hydroxyurea or antimetabolite therapy Cancer 106 1730 1738 16532439 10.1002/cncr.21797 1:CAS:528:DC%2BD28XksFCkurc%3D
27. B Johansson T Fioretos F Mitelman 2002 Cytogenetic and molecular genetic evolution of chronic myeloid leukemia Acta Haematol 107 76 94 11919388 10.1159/000046636 1:CAS:528:DC%2BD38XitlGmsLs%3D
28. A Majlis TL Smith M Talpaz S O'Brien MB Rios HM Kantarjian 1996 Significance of cytogenetic clonal evolution in chronic myelogenous leukemia J Clin Oncol 14 196 203 8558198 1:STN:280:DyaK287ktVejsg%3D%3D
29. ME O'Dwyer MJ Mauro G Kurilik, et al. 2002 The impact of clonal evolution on response to imatinib mesylate (STI571) in accelerated phase CML Blood 100 1628 1633 12176881 10.1182/blood-2002-03-0777
30. ME O'Dwyer MJ Mauro C Blasdel, et al. 2004 Clonal evolution and lack of cytogenetic response are adverse prognostic factors for hematologic relapse of chronic phase CML patients treated with imatinib mesylate Blood 103 451 455 14512312 10.1182/blood-2003-02-0371
31. D Verma H Kantarjian J Shan, et al. 2010 Survival outcomes for clonal evolution in chronic myeloid leukemia patients on second generation tyrosine kinase inhibitor therapy Cancer 116 2673 2681 20499401 1:CAS:528: DC%2BC3cXnvFKjtLY%3D
32. A Fabarius A Leitner A Hochhaus, et al. 2010 Impact of additional cytogenetic aberrations at diagnosis on prognosis of CML: long-term observation of 1151 patients from the randomized CML study IV Blood 118 6760 6768 10.1182/blood-2011-08-373902
33. MM El-Zimaity H Kantarjian M Talpaz, et al. 2004 Results of imatinib mesylate therapy in chronic myelogenous leukaemia with variant Philadelphia chromosome Br J Haematol 125 187 195 15059141 10.1111/j.1365-2141.2004.04899.x 1:CAS:528:DC%2BD2cXktlKrsLo%3D
34. M Gorusu P Benn ZH Li M Fang 2007 On the genesis and prognosis of variant translocations in chronic myeloid leukemia Cancer Genet Cytogenet 173 97 106 17321324 10.1016/j.cancergencyto.2006.10.006 1:CAS:528:DC%2BD2sXitFOgs7Y%3D
35. PB Sinclair EP Nacheva M Leversha, et al. 2000 Large deletions at the t(9;22) breakpoint are common and may identify a poor-prognosis subgroup of patients with chronic myeloid leukemia Blood 95 738 743 10648381 1:CAS:528:DC%2BD3cXotV2jtw%3D%3D
36. BJ Huntly AG Reid AJ Bench, et al. 2001 Deletions of the derivative chromosome 9 occur at the time of the Philadelphia translocation and provide a powerful and independent prognostic indicator in chronic myeloid leukemia Blood 98 1732 1738 11535505 10.1182/blood.V98.6.1732 1:CAS:528:DC%2BD3MXntFWgsb0%3D
37. G Marzocchi F Castagnetti S Luatti, et al. 2011 Variant Philadelphia translocations: molecular-cytogenetic characterization and prognostic influence on frontline imatinib therapy, a GIMEMA WP on CML analysis Blood 117 6793 6800 21447834 10.1182/blood-2011-01-328294 1:CAS:528:DC%2BC3MXoslChsL0%3D
38. JL Diezmartin GW Dewald RV Pierre 1988 Possible cytogenetic distinction between lymphoid and myeloid blast crisis in chronic granulocytic-leukemia Am J Hematol 27 194 203 10.1002/ajh.2830270309 1:STN:280:DyaL1c7mtFSgsw%3D%3D
39. EP Nacheva D Brazma A Virgili, et al. 2010 Deletions of immunoglobulin heavy chain and T cell receptor gene regions are uniquely associated with lymphoid blast transformation of chronic myeloid leukemia Bmc Genomics 11 41 20082691 10.1186/1471-2164-11-41
40. U Bacher W Kern S Schnittger W Hiddemann C Schoch T Haferlach 2005 Further correlations of morphology according to FAB and WHO classification to cytogenetics in de novo acute myeloid leukemia: a study on 2,235 patients Ann Hematol 84 785 791 16132906 10.1007/s00277-005-1099-0
41. MC Bene M Bernier RO Casasnovas, et al. 2001 Acute myeloid leukaemia MO: haematological, immunophenotypic and cytogenetic characteristics and their prognostic significance: an analysis in 241 patients Br J Haematol 113 737 745 11380465 10.1046/j.1365-2141.2001.02801.x 1:STN:280:DC%2BD3Mzks1SltQ%3D%3D