Dingxin recipe prevents ischemia/reperfusion- Induced arrhythmias via up-regulating prohibitin and suppressing inflammatory responses

Chinese Journal of Integrative Medicine

Volumn 18, Issue 2, 2012, Pages 120-129

  Jia, Yu Hua ^a   Zhang, Yun Xian ^b   Li, Li Jun ^a   Liu, Ya Wei ^a   Li, Chun Hua ^a   Fu, Xiu Qiong ^a   Zeng, Ping ^c   Wu, Wei Kang ^d   Sun, Xue Gang ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b Fuda Cancer Hospital of Guangzhou   (China)

^c GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^d SUN YAT SEN UNIVERSITY   (China)

Author keywords

Arrhythmias; Dingxin Recipe; Inflammation; Ischemia reperfusion; Prohibitin; Proteomics

Indexed keywords

ANTIARRHYTHMIC AGENT; CHINESE DRUG; DINGXIN RECIPE; FATTY ACID BINDING PROTEIN; GLUTATHIONE; INTERLEUKIN 6; PROHIBITIN; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIARRHYTHMIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DISEASE DURATION; ELECTROCARDIOGRAM; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART ARRHYTHMIA; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; IMMUNOHISTOCHEMISTRY; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MORTALITY; NEUTROPHIL CHEMOTAXIS; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; SHAM PROCEDURE; TREATMENT DURATION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ARRHYTHMIAS, CARDIAC; DRUGS, CHINESE HERBAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FATTY ACID-BINDING PROTEINS; GLUTATHIONE; HEART VENTRICLES; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERLEUKIN-6; MALE; MYOCARDIAL INFARCTION; NEUTROPHIL INFILTRATION; PEPTIDE MAPPING; PROTEOMICS; RATS; RATS, WISTAR; REPERFUSION INJURY; REPRESSOR PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SPECTROPHOTOMETRY; UP-REGULATION;

EID: 84862741915     PISSN: 16720415     EISSN: 19930402     Source Type: Journal    
DOI: 10.1007/s11655-012-0998-x     Document Type: Article

References (49)

1. Gheorghiade M, Bonow RO. Chronic heart failure in the United States: a manifestation of coronary artery disease. Circulation 1998;97:282-289. (Pubitemid 28067315)
2. Meldrum DR. Tumor necrosis factor in the heart. Am J Physiol Regul Integr Comp Physiol 1998;274:R577-R595.
3. Chandrasekar B, Mitchell DH, Colston JT, Freeman GL. Regulation of CCAAT/Enhancer binding protein, interleukin-6, interleukin-6 receptor, and gp130 expression during myocardial ischemia/reperfusion. Circulation 1999; 99:427-433. (Pubitemid 29051270)
4. Kukielka GL, Smith CW, LaRosa GJ, Manning AM, Mendoza LH, Daly TJ, et al. Interleukin-8 gene induction in the myocardium after ischemia and reperfusion in vivo. J Clin Invest 1995;95:89-103.
5. Lucchesi BR, Kilgore KS. Complement in hibitors in my ocardial is chemia/reperfusioninjury. Immunopharmacology 1997;38:27-42.
6. Vinten-Johansen J, Jiang R, Reeves JG, Mykytenko J, Deneve J, Jobe LJ. Inflammation, proinflammatory mediators and myocardial ischemia-reperfusion injury. Hematol Oncol Clin North Am 2007;21:123-145. (Pubitemid 46156986)
7. Albertine KH, Weyrich AS, Ma XL, Lefer DJ, Becker LC, Lefer AM. Quantification of neutrophil migration following myocardial ischemia and reperfusion in cats and dogs. J Leukoc Biol 1994;55:557-566. (Pubitemid 24171721)
8. Lefer AM, Ma XL, Weyrich A, Lefer DJ. Endothelial dysfunction and neutrophil adherence as critical events in the development of reperfusion injury. Agents Actions Suppl 1993;4:127-135. (Pubitemid 23149622)
9. Chen JK, Chow SE. Antioxidants and myocardial ischemia: reperfusion injuries. Chang Gung Med J 2005;28:369-377.
10. Jia YH, Sun XG, Jia MY, Cui ZY, Li CX. Observation of the effects of Dingxin Recipe on 145 tachyarrhythmia patients. J Pract Tradit Chin Med (Chin) 1999;15:3-4.
11. Jia YH, Yu LZ, Chen YY, Zhou YL, Sun XG. Effect of Dingxin Recipe on arrhythmia and injury induced by ischemia and reperfusion in rabbits. Chin J Integr Tradit West Med (Chin)1999;19:678-681.
12. Jia YH, Chen YY, Zhou YL, Sun XG. A. Effects of Dingxin Recipe on arrhythmias induced by ischemia/reperfusion. Chin Gen Pract (Chin) 1999;2:126-128.
13. Zhao XS, Jia YH, Jiang Y, Luo R, Qin QH. Effects of Dingxin Recipe on p38 mitogen activated protein kinase and tumor necrosis factor alpha of myocardial ischemia reperfusion injury in rats. Chin J Clin Rehabil (Chin) 2004; 8:2882-2884. (Pubitemid 39029921)
14. Jia YH, Zhang YX, Zhou YP, Sun XG. Effects of Dingxin Recipe and oxymatrine on reperfusion arrhythmias with rats and expression of ICAM-1. Liaoning J Tradit Chin Med (Chin) 2008;35:32-34.
15. Jia YH, Sun XG, Chen YY. Effects of Dingxin Recipe and tanshinose ?A on expression of platelet membrane adhesive molecule in the rat of arrhythmia. J Tradit Chin Med (Chin) 2002;43:140-142.
16. Jia YH, Zhou YP, Chen YY, Zhang YX, Sun XG. Protective effect of Dingxin Formula on arrhythmia rats with myocardial ischemical reperfusion injury and its effect on NF-κB activation. J Tradit Chin Med (Chin) 2007;48:357-359.
17. Himori N, Matsuura A. A simple technique for occlusion and reperfusion of coronary artery in conscious rats. Am J Physiol 1989;256:H1719-H1725.
18. Walker MJ, Curtis MJ, Hearse DJ, Campbell RW, Janse MJ, Yellon DM, et al. The Lambeth Conventions: guidelines for the study of arrhythmias in ischaemia infarction, and reperfusion. Cardiovasc Res 1988;22:447-455.
19. Leprán I, Baczkó I, Varró A , Papp JG. ATP-sensitive potassium channel modulators: both pinacidil and glibenclamide produce antiarrhythmic activity during acute myocardial infarction in conscious rats. J Pharmacol Exp Ther 1996;277:1215-1220.
20. Guo R, Gao XY, Wang W, Wang HJ, Zhang F, Zhang Y, et al. Tempol reduces reperfusion-induced arrhythmias in anaesthetized rats. Pharmacol Res 2005;52:192-198. (Pubitemid 40828371)
21. Fishbein MC, Meerbaum S, Rit J, Lando U, Kanmatsuse K, Mercier JC, et al. Early phase acute myocardial infarct size quantification: validation of the triphenyl tetrazolium chloride tissue enzyme staining technique. Am Heart J 1981;101:593-600. (Pubitemid 11120523)
22. Liu L, Zhao L, Zhang Y, Zhang Q, Ding Y. Proteomic analysis of Tiam1-mediated metastasis in colorectal cancer. Cell Biol Int 2007;31:805-814. (Pubitemid 46765138)
23. de Jonge N, van Wichen DF, Schipper ME, Lahpor JR, Gmelig-Meyling FH, Robles de Medina EO, et al. Left ventricular assist device in end-stage heart failure: persistence of structural myocyte damage after unloading. An immunohistochemical analysis of the contractile myofilaments. J Am Coll Cardiol 2002;39:963-969. (Pubitemid 34234117)
24. Song G, Zhao X, Xu J, Song H. Increased expression of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in rat cardiac allografts. Transplant Proc 2008;40:2720-2723.
25. Li M, Georgakopoulos D, Lu G, Hester L, Kass DA, Hasday J, et al. p38 MAP kinase mediates inflammatory cytokine induction in cardiomyocytes and extracellular matrix remodeling in heart. Circulation 2005;111:2494-2502. (Pubitemid 40696138)
26. Acevedo M, Corbalán R, Braun S, Pereira J, Navarrete C, Gonzalez I. C-reactive protein and atrial fibrillation: "evidence for the presence of inflammation in the perpetuation of the arrhythmia." Int J Cardiol 2006;108:326-331. (Pubitemid 43348338)
27. Engelman DT, Watanabe M, Maulik N, Cordis GA, Engelman RM, Rousou JA, et al. L-arginine reduces endothelial inflammation and myocardial stunning during ischemia/reperfusion. Ann Thorac Surg 1995;60:1275-1281.
28. Li XL, Chu WM, Liu JL. Antiarrhythmic properties of longterm treatment with matrine in arrhythmic rat induced by coronary ligation. Biol Pharm Bull 2009;32:1521-1526.
29. Huang WM, Wu ZD, Gan YQ. Effects of berberine on ischemic ventricular arrhythmia. Chin J Cardiol 1989;17:300-301, 319.
30. Sun DD, Wang HC, Wang XB, Luo Y, Jin ZX, Li ZC, et al. Tanshinone ?A: a new activator of human cardiac KCNQ1/KCNE1 (Iks) potassium channels. Eur J Pharmacol 2008;590:317-321.
31. Zhang LH, Jia YH, Sun XG, Xing FY, Liu ZF, Song G, et al. Effects of total Panax notoginseng saponins on the activity of human nitric oxide synthase gene promotor. J First Milit Med Univ (Chin) 2004;24:1113-1116.
32. Gao BY, Li XJ, Liu L, Zhang BH. Effect of panaxatriol saponins isolated from Panax notoginseng (PTS) on myocardial ischemic arrhythmia in mice and rats. Acta Pharm Sin (Chin) 1992;27:641-644.
33. Chen XJ, Yu CL, Liu JF. Protective effects of total saponins of semen Ziziphi spinosae on cultured rat myocardial cells. Acta Pharmacol Sin 1990;11:153-155.
34. Lai KN, Chan LY, Tang SC, Leung JC. Ganoderma extract prevents albumin-induced oxidative damage and chemokines synthesis in cultured human proximal tubular epithelial cells. Nephrol Dial Transplant 2006;21:1188-1197.
35. Jia YH, Sun XG, Zhao XS. Effect of Dingxin Recipe on intracellular free calcium, membrane potential and mitochondria membrane potential in normal and hypoxia myocytes of rats. Chin J Integr Tradit West Med (Chin) 2001;21:680-683.
36. Knowlton AA, Apstein CS, Saouf R, Brecher P. Leakage of heart fatty acid binding protein with ischemia and reperfusion in the rat. J Mol Cell Cardiol 1989;21:577-583. (Pubitemid 19222704)
37. Glatz JF, van Bilsen M, Paulussen RJ, Veerkamp JH, van der Vusse GJ, Reneman RS. Release of fatty acid-binding protein from isolated rat heart subjected to ischemia and reperfusion or to the calcium paradox. Biochim Biophys Acta 1988;961:148-152.
38. Ikonen E, Fiedler K, Parton RG, Simons K. Prohibitin, an antiproliferative protein, is localized to mitochondria. FEBS Lett 1995;358:273-277.
39. Kasashima K, Sumitani M, Satoh M, Endo H. Human prohibitin 1 maintains the organization and stability of the mitochondrial nucleoids. Exp Cell Res 2008;314:988-996.
40. Nuell MJ, Stewart DA, Walker L, Friedman V, Wood CM, Owens GA, et al. Prohibitin, an evolutionarily conserved intracellular protein that blocks DNA synthesis in normal fibroblasts and HeLa cells. Mol Cell Biol 1991;11:1372-1381. (Pubitemid 21895493)
41. Terashima M, Kim KM, Adachi T, Nielsen PJ, Reth M, Köhler G, et al. The IgM antigen receptor of B lymphocytes is associated with prohibitin and a prohibitin-related protein. EMBO J 1994;13:3782-3792. (Pubitemid 24275024)
42. Rajalingam K, Rudel T. Ras-Raf signaling needs prohibitin. Cell cycle 2005;4:1503-1505.
43. Coates PJ, Jamieson DJ, Smart K, Prescott AR, Hall PA. The prohibitin family of mitochondrial proteins regulate replicative lifespan. Curr Biol 1997;7:607-610.
44. Liu X, Ren Z, Zhan R, Wang X, Wang X, Zhang Z, et al. Prohibitin protects against oxidative stress-induced cell injury in cultured neonatal cardiomyocyte. Cell Stress Chaperones 2009;14:311-319.
45. Theiss AL, Idell RD, Srinivasan S, Klapproth JM, Jones DP, Merlin D, et al. Prohibitin protects against oxidative stress in intestinal epithelial cells. FASEB J 2007;21:197-206. (Pubitemid 46052557)
46. Theiss AL, Jenkins AK, Okoro NI, Klapproth JM, Merlin D, Sitaraman SV. Prohibitin inhibits tumor necrosis factor alpha-induced nuclear factor-kappa B nuclear translocation via the novel mechanism of decreasing importin α3 expression. Mol Biol Cell 2009;20:4412-4423.
47. Daemen MA, van't Veer C, Denecker G, Heemskerk VH, Wolfs TG, Lauss CM, et al. Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation. J Clin Invest 1999;104:541-549.
48. Zhou YP, Jia YH, Yang P, Chen YY, Zhang YX, Sun XG. The effects of Dingxin Recipe on myocardial apoptosis in ischemia/reperfusion induced arrhythmias in rats. Chin J Basic Med Tradit Chin Med (Chin) 2007;13:515-516.
49. Fusaro G, Wang S, Chellappan S. Differential regulation of Rb family proteins and prohibitin during camptothecininduced apoptosis. Oncogene 2002;21:4539-4548. (Pubitemid 34785730)