-
1
-
-
0033540056
-
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
-
Kojima M, Hosoda H, Date Y et al. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402(6762), 656-660 (1999).
-
(1999)
Nature
, vol.402
, Issue.6762
, pp. 656-660
-
-
Kojima, M.1
Hosoda, H.2
Date, Y.3
-
2
-
-
38849090670
-
Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone
-
Yang J, Brown MS, Liang G, Grishin NV, Goldstein JL. Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone. Cell 132(3), 387-396 (2008).
-
(2008)
Cell
, vol.132
, Issue.3
, pp. 387-396
-
-
Yang, J.1
Brown, M.S.2
Liang, G.3
Grishin, N.V.4
Goldstein, J.L.5
-
3
-
-
0035320623
-
Ghrelin: Discovery of the natural endogenous ligand for the growth hormone secretagogue receptor
-
Kojima M, Hosoda H, Matsuo H, KangawaK. Ghrelin: discovery of the natural endogenous ligand for the growth hormone secretagogue receptor. Trends Endocrinol. Metab. 12(3), 118-122 (2001).
-
(2001)
Trends Endocrinol. Metab
, vol.12
, Issue.3
, pp. 118-122
-
-
Kojima, M.1
Hosoda, H.2
Matsuo, H.3
KangawaK4
-
4
-
-
0035843183
-
A role for ghrelin in the central regulation of feeding
-
Nakazato M, Murakami N, Date Y et al. A role for ghrelin in the central regulation of feeding. Nature 409(6817), 194-198 (2001).
-
(2001)
Nature
, vol.409
, Issue.6817
, pp. 194-198
-
-
Nakazato, M.1
Murakami, N.2
Date, Y.3
-
5
-
-
0034802108
-
Minireview: Ghrelin and the regulation of energy balance - a hypothalamic perspective
-
Horvath TL, Diano S, Sotonyi P, Heiman M, Tschop M. Minireview: ghrelin and the regulation of energy balance - a hypothalamic perspective. Endocrinology 142(10), 4163-4169 (2001).
-
(2001)
Endocrinology
, vol.142
, Issue.10
, pp. 4163-4169
-
-
Horvath, T.L.1
Diano, S.2
Sotonyi, P.3
Heiman, M.4
Tschop, M.5
-
6
-
-
0036787457
-
The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats
-
Date Y, Murakami N, Toshinai K et al. The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats. Gastroenterology 123(4), 1120-1128 (2002).
-
(2002)
Gastroenterology
, vol.123
, Issue.4
, pp. 1120-1128
-
-
Date, Y.1
Murakami, N.2
Toshinai, K.3
-
7
-
-
33748664379
-
Drug insight: The functions of ghrelin and its potential as a multitherapeutic hormone
-
Kojima M, Kangawa K. Drug insight: the functions of ghrelin and its potential as a multitherapeutic hormone. Nat. Clin. Prac. 2(2), 80-88 (2006).
-
(2006)
Nat. Clin. Prac
, vol.2
, Issue.2
, pp. 80-88
-
-
Kojima, M.1
Kangawa, K.2
-
8
-
-
0242383502
-
Effect of ghrelin and synthetic growth hormone secretagogues in normal and ischemic rat heart
-
Frascarelli S, Ghelardoni S, Ronca-Testoni S, Zucchi R. Effect of ghrelin and synthetic growth hormone secretagogues in normal and ischemic rat heart. Basic Res. Cardiol. 98(6), 401-405 (2003).
-
(2003)
Basic Res. Cardiol
, vol.98
, Issue.6
, pp. 401-405
-
-
Frascarelli, S.1
Ghelardoni, S.2
Ronca-Testoni, S.3
Zucchi, R.4
-
9
-
-
4544253380
-
Ghrelin protects myocardium from isoproterenol-induced injury in rats
-
Chang L, Zhao J, Li GZ et al. Ghrelin protects myocardium from isoproterenol-induced injury in rats. Acta Pharmacol. Sin. 25(9), 1131-1137 (2004).
-
(2004)
Acta Pharmacol. Sin
, vol.25
, Issue.9
, pp. 1131-1137
-
-
Chang, L.1
Zhao, J.2
Li, G.Z.3
-
10
-
-
33646231528
-
Cardioprotective effects of ghrelin and des-octanoyl ghrelin on myocardial injury induced by isoproterenol in rats
-
Li L, Zhang LK, Pang YZ et al. Cardioprotective effects of ghrelin and des-octanoyl ghrelin on myocardial injury induced by isoproterenol in rats. Acta Pharmacol. Sin. 27(5), 527-535 (2006).
-
(2006)
Acta Pharmacol. Sin
, vol.27
, Issue.5
, pp. 527-535
-
-
Li, L.1
Zhang, L.K.2
Pang, Y.Z.3
-
11
-
-
0035940390
-
Elevated circulating level of ghrelin in cachexia associated with chronic heart failure: Relationships between ghrelin and anabolic/catabolic factors
-
Nagaya N, Uematsu M, Kojima M et al. Elevated circulating level of ghrelin in cachexia associated with chronic heart failure: relationships between ghrelin and anabolic/catabolic factors. Circulation 104(17), 2034-2038 (2001).
-
(2001)
Circulation
, vol.104
, Issue.17
, pp. 2034-2038
-
-
Nagaya, N.1
Uematsu, M.2
Kojima, M.3
-
12
-
-
20844460120
-
Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure
-
Nagaya N, Moriya J, Yasumura Y et al. Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure. Circulation 110(24), 3674-3679 (2004).
-
(2004)
Circulation
, vol.110
, Issue.24
, pp. 3674-3679
-
-
Nagaya, N.1
Moriya, J.2
Yasumura, Y.3
-
13
-
-
9344258621
-
Endogenous production of ghrelin and beneficial effects of its exogenous administration in monocrotaline-induced pulmonary hypertension
-
Henriques-Coelho T, Correia-Pinto J, Roncon-Albuquerque R Jr et al. Endogenous production of ghrelin and beneficial effects of its exogenous administration in monocrotaline-induced pulmonary hypertension. Am. J. Physiol. 287(6), H2885-H2890 (2004).
-
(2004)
Am. J. Physiol
, vol.287
, Issue.6
-
-
Henriques-Coelho, T.1
Correia-Pinto, J.2
Roncon-Albuquerque Jr, R.3
-
14
-
-
3042735648
-
The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans
-
Gnanapavan S, Kola B, Bustin SA et al. The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans. J. Endocrinol. Metab. 87(6), 2988 (2002).
-
(2002)
J. Endocrinol. Metab
, vol.87
, Issue.6
, pp. 2988
-
-
Gnanapavan, S.1
Kola, B.2
Bustin, S.A.3
-
15
-
-
0035908954
-
Chronic administration of ghrelin improves left ventricular dysfunction and attenuates development of cardiac cachexia in rats with heart failure
-
Nagaya N, Uematsu M, Kojima M et al. Chronic administration of ghrelin improves left ventricular dysfunction and attenuates development of cardiac cachexia in rats with heart failure. Circulation 104(12), 1430-1435 (2001).
-
(2001)
Circulation
, vol.104
, Issue.12
, pp. 1430-1435
-
-
Nagaya, N.1
Uematsu, M.2
Kojima, M.3
-
16
-
-
38149032717
-
Ghrelin suppresses cardiac sympathetic activity and prevents early left ventricular remodeling in rats with myocardial infarction
-
Soeki T, Kishimoto I, Schwenke DO et al. Ghrelin suppresses cardiac sympathetic activity and prevents early left ventricular remodeling in rats with myocardial infarction. Am. J. Physiol. 294(1), H426-H432 (2008).
-
(2008)
Am. J. Physiol
, vol.294
, Issue.1
-
-
Soeki, T.1
Kishimoto, I.2
Schwenke, D.O.3
-
17
-
-
53249154955
-
Early ghrelin treatment after myocardial infarction prevents an increase in cardiac sympathetic tone and reduces mortality
-
Schwenke DO, Tokudome T, Kishimoto I et al. Early ghrelin treatment after myocardial infarction prevents an increase in cardiac sympathetic tone and reduces mortality. Endocrinology 149(10), 5172-5176 (2008).
-
(2008)
Endocrinology
, vol.149
, Issue.10
, pp. 5172-5176
-
-
Schwenke, D.O.1
Tokudome, T.2
Kishimoto, I.3
-
18
-
-
37549060716
-
Exogenous ghrelin attenuates the progression of chronic hypoxia-induced pulmonary hypertension in conscious rats
-
Schwenke DO, Tokudome T, Shirai M et al. Exogenous ghrelin attenuates the progression of chronic hypoxia-induced pulmonary hypertension in conscious rats. Endocrinology 149(1), 237-244 (2008).
-
(2008)
Endocrinology
, vol.149
, Issue.1
, pp. 237-244
-
-
Schwenke, D.O.1
Tokudome, T.2
Shirai, M.3
-
19
-
-
0040184557
-
Ghrelin strongly stimulates growth hormone release in humans
-
Takaya K, Ariyasu H, Kanamoto N et al. Ghrelin strongly stimulates growth hormone release in humans. J. Endocrinol. Metab. 85(12), 4908-4911 (2000).
-
(2000)
J. Endocrinol. Metab
, vol.85
, Issue.12
, pp. 4908-4911
-
-
Takaya, K.1
Ariyasu, H.2
Kanamoto, N.3
-
20
-
-
0033805978
-
Preliminary evidence that ghrelin, the natural GH secretagogue (GHS)-receptor ligand, strongly stimulates GH secretion in humans
-
Arvat E, Di Vito L, Broglio F et al. Preliminary evidence that ghrelin, the natural GH secretagogue (GHS)-receptor ligand, strongly stimulates GH secretion in humans. J. Endocrinol. Invest. 23(8), 493-495 (2000).
-
(2000)
J. Endocrinol. Invest
, vol.23
, Issue.8
, pp. 493-495
-
-
Arvat, E.1
Di Vito, L.2
Broglio, F.3
-
21
-
-
0035026511
-
Hemodynamic and hormonal effects of human ghrelin in healthy volunteers
-
Nagaya N, Kojima M, Uematsu M et al. Hemodynamic and hormonal effects of human ghrelin in healthy volunteers. Am. J. Physiol. 280(5), R1483-R1487 (2001).
-
(2001)
Am. J. Physiol
, vol.280
, Issue.5
-
-
Nagaya, N.1
Kojima, M.2
Uematsu, M.3
-
22
-
-
5444263815
-
There are no acute cardiac effects of a single iv dose of human ghrelin in severe growth hormone deficient patients
-
Janssen JA, Poldermans D, Holland LJ et al. There are no acute cardiac effects of a single iv dose of human ghrelin in severe growth hormone deficient patients. J. Endocrinol. Invest. 27(7), 659-664 (2004).
-
(2004)
J. Endocrinol. Invest
, vol.27
, Issue.7
, pp. 659-664
-
-
Janssen, J.A.1
Poldermans, D.2
Holland, L.J.3
-
23
-
-
0038410093
-
Ghrelin plays a minor role in the physiological control of cardiac function in the rat
-
Torsello A, Bresciani E, Rossoni G et al. Ghrelin plays a minor role in the physiological control of cardiac function in the rat. Endocrinology 144(5), 1787-1792 (2003).
-
(2003)
Endocrinology
, vol.144
, Issue.5
, pp. 1787-1792
-
-
Torsello, A.1
Bresciani, E.2
Rossoni, G.3
-
24
-
-
0034687376
-
Ghrelin induces adiposity in rodents
-
Tschop M, Smiley DL, Heiman ML. Ghrelin induces adiposity in rodents. Nature 407(6806), 908-913 (2000).
-
(2000)
Nature
, vol.407
, Issue.6806
, pp. 908-913
-
-
Tschop, M.1
Smiley, D.L.2
Heiman, M.L.3
-
25
-
-
0033711116
-
The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion
-
Wren AM, Small CJ, Ward HL et al. The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology 141(11), 4325-4328 (2000).
-
(2000)
Endocrinology
, vol.141
, Issue.11
, pp. 4325-4328
-
-
Wren, A.M.1
Small, C.J.2
Ward, H.L.3
-
26
-
-
17944380559
-
A role of ghrelin in neuroendocrine and behavioral responses to stress in mice
-
Asakawa A, Inui A, Kaga T et al. A role of ghrelin in neuroendocrine and behavioral responses to stress in mice. Neuroendocrinology 74(3), 143-147 (2001).
-
(2001)
Neuroendocrinology
, vol.74
, Issue.3
, pp. 143-147
-
-
Asakawa, A.1
Inui, A.2
Kaga, T.3
-
27
-
-
0034809159
-
Upregulation of ghrelin expression in the stomach upon fasting, insulin-induced hypoglycemia, and leptin administration
-
Toshinai K, Mondal MS, Nakazato M et al. Upregulation of ghrelin expression in the stomach upon fasting, insulin-induced hypoglycemia, and leptin administration. Biochem. Biophys. Res. Commun. 281(5), 1220-1225 (2001).
-
(2001)
Biochem. Biophys. Res. Commun
, vol.281
, Issue.5
, pp. 1220-1225
-
-
Toshinai, K.1
Mondal, M.S.2
Nakazato, M.3
-
28
-
-
0034741715
-
125I-His(9)]-ghrelin, a novel radioligand for localizing GHS orphan receptors in human and rat tissue: Up-regulation of receptors with athersclerosis
-
125I-His(9)]-ghrelin, a novel radioligand for localizing GHS orphan receptors in human and rat tissue: up-regulation of receptors with athersclerosis. Br. J. Pharmacol. 134(1), 143-149 (2001).
-
(2001)
Br. J. Pharmacol
, vol.134
, Issue.1
, pp. 143-149
-
-
Katugampola, S.D.1
Pallikaros, Z.2
Davenport, A.P.3
-
29
-
-
0036102978
-
Vasodilatory effect of ghrelin, an endogenous peptide from the stomach
-
Okumura H, Nagaya N, Enomoto M et al. Vasodilatory effect of ghrelin, an endogenous peptide from the stomach. J. Cardiovasc. Pharmacol. 39(6), 779-783 (2002).
-
(2002)
J. Cardiovasc. Pharmacol
, vol.39
, Issue.6
, pp. 779-783
-
-
Okumura, H.1
Nagaya, N.2
Enomoto, M.3
-
30
-
-
0036687932
-
Comparison of vasodilators in human internal mammary artery: Ghrelin is a potent physiological antagonist of endothelin-1
-
Wiley KE, Davenport AP. Comparison of vasodilators in human internal mammary artery: ghrelin is a potent physiological antagonist of endothelin-1. Br. J. Pharmacol. 136(8), 1146-1152 (2002).
-
(2002)
Br. J. Pharmacol
, vol.136
, Issue.8
, pp. 1146-1152
-
-
Wiley, K.E.1
Davenport, A.P.2
-
31
-
-
0037164747
-
Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT
-
Baldanzi G, Filigheddu N, Cutrupi S et al. Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT. J. Cell. Biol. 159(6), 1029-1037 (2002).
-
(2002)
J. Cell. Biol
, vol.159
, Issue.6
, pp. 1029-1037
-
-
Baldanzi, G.1
Filigheddu, N.2
Cutrupi, S.3
-
32
-
-
2342620868
-
Ghrelin acts at the nucleus of the solitary tract to decrease arterial pressure in rats
-
Lin Y, Matsumura K, Fukuhara M et al. Ghrelin acts at the nucleus of the solitary tract to decrease arterial pressure in rats. Hypertension 43(5), 977-982 (2004).
-
(2004)
Hypertension
, vol.43
, Issue.5
, pp. 977-982
-
-
Lin, Y.1
Matsumura, K.2
Fukuhara, M.3
-
33
-
-
0036144322
-
Acute central ghrelin and GH secretagogues induce feeding and activate brain appetite centers
-
Lawrence CB, Snape AC, Baudoin FM et al. Acute central ghrelin and GH secretagogues induce feeding and activate brain appetite centers. Endocrinology 143(1), 155-162 (2002).
-
(2002)
Endocrinology
, vol.143
, Issue.1
, pp. 155-162
-
-
Lawrence, C.B.1
Snape, A.C.2
Baudoin, F.M.3
-
34
-
-
0034726741
-
Central effects of a novel acylated peptide, ghrelin, on growth hormone release in rats
-
Date Y, Murakami N, Kojima M et al. Central effects of a novel acylated peptide, ghrelin, on growth hormone release in rats. Biochem. Biophys. Res. Commun. 275(2), 477-480 (2000).
-
(2000)
Biochem. Biophys. Res. Commun
, vol.275
, Issue.2
, pp. 477-480
-
-
Date, Y.1
Murakami, N.2
Kojima, M.3
-
36
-
-
0037066587
-
Neuroendocrine and peripheral activities of ghrelin: Implications in metabolism and obesity
-
Muccioli G, Tschöp M, Papotti M et al. Neuroendocrine and peripheral activities of ghrelin: implications in metabolism and obesity. Eur. J. Pharmacol. 440(2-3), 235-254 (2002).
-
(2002)
Eur. J. Pharmacol
, vol.440
, Issue.2-3
, pp. 235-254
-
-
Muccioli, G.1
Tschöp, M.2
Papotti, M.3
-
37
-
-
33750625913
-
Translational research on the clinical applications of ghrelin
-
Akamizu T, Kangawa K. Translational research on the clinical applications of ghrelin. Endocr. J. 53(5), 585-591 (2006).
-
(2006)
Endocr. J
, vol.53
, Issue.5
, pp. 585-591
-
-
Akamizu, T.1
Kangawa, K.2
-
38
-
-
41749120794
-
Repeated administration of ghrelin to patients with functional dyspepsia: Its effects on food intake and appetite
-
Akamizu T, Iwakura H, Ariyasu H et al. Repeated administration of ghrelin to patients with functional dyspepsia: its effects on food intake and appetite. Eur. J. Endocrinol. 158(4), 491-498 (2008).
-
(2008)
Eur. J. Endocrinol
, vol.158
, Issue.4
, pp. 491-498
-
-
Akamizu, T.1
Iwakura, H.2
Ariyasu, H.3
-
39
-
-
57149137502
-
Effects of ghrelin treatment on patients undergoing total hip replacement for osteoarthritis: Different outcomes from studies in patients with cardiac and pulmonary cachexia
-
Akamizu T, Iwakura H, Ariyasu H et al. Effects of ghrelin treatment on patients undergoing total hip replacement for osteoarthritis: different outcomes from studies in patients with cardiac and pulmonary cachexia. J. Am. Geriatr. Soc. 56(12), 2363-2365 (2008).
-
(2008)
J. Am. Geriatr. Soc
, vol.56
, Issue.12
, pp. 2363-2365
-
-
Akamizu, T.1
Iwakura, H.2
Ariyasu, H.3
|