-
1
-
-
18244383791
-
Familiar recurrence rates and genetic models of multiple sclerosis
-
Lyndsay JW (2005) Familiar recurrence rates and genetic models of multiple sclerosis. Am J Med Genet 135:53-58
-
(2005)
Am J Med Genet
, vol.135
, pp. 53-58
-
-
Lyndsay, J.W.1
-
2
-
-
54149084585
-
Multiple sclerosis
-
Compston A, Coles A (2008) Multiple sclerosis. Lancet 372 (9648):1502-1017
-
(2008)
Lancet
, vol.372
, Issue.9648
, pp. 1502-11017
-
-
Compston, A.1
Coles, A.2
-
4
-
-
34548299105
-
Risk alleles for multiple sclerosis identified by a genomewide study
-
The International Multiple Sclerosis Genetics Consortium
-
The International Multiple Sclerosis Genetics Consortium (2007) Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med 357(9):851-862
-
(2007)
N Engl J Med
, vol.357
, Issue.9
, pp. 851-862
-
-
-
5
-
-
49849091315
-
Refining genetic associations in multiple sclerosis
-
International Multiple Sclerosis Genetics Consortium (IMSGC)
-
International Multiple Sclerosis Genetics Consortium (IMSGC) (2008) Refining genetic associations in multiple sclerosis. Lancet Neurol 7(7):567-5699
-
(2008)
Lancet Neurol
, vol.7
, Issue.7
, pp. 567-5699
-
-
-
6
-
-
34548368541
-
Variation in interleukin 7 receptor (IL7R) alpha gene influences risk of multiple sclerosis
-
Lundmark F, Duvefelt K, Iacobaeus E, Kockum I, Wallström E, Khademi M, Oturai A, Ryder LP, Saarele J, Harbbo HF, Celius EG, Salter H, Olsson T, Hillert J (2007) Variation in interleukin 7 receptor (IL7R) alpha gene influences risk of multiple sclerosis. Nat Genet 39(9):1108-1113
-
(2007)
Nat Genet
, vol.39
, Issue.9
, pp. 1108-1113
-
-
Lundmark, F.1
Duvefelt, K.2
Iacobaeus, E.3
Kockum, I.4
Wallström, E.5
Khademi, M.6
Oturai, A.7
Ryder, L.P.8
Saarele, J.9
Harbbo, H.F.10
Celius, E.G.11
Salter, H.12
Olsson, T.13
Hillert, J.14
-
7
-
-
42549108701
-
IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations
-
Weber F, Fontaine B, Cournu-Rebeix I, Kroner A, Knop M, Lutz S, Müller-Sarnowski F, Uhr M, Bettecken T, Kohli M et al (2008) IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations. Genes Immun 9 (3):259-263
-
(2008)
Genes Immun
, vol.9
, Issue.3
, pp. 259-263
-
-
Weber, F.1
Fontaine, B.2
Cournu-Rebeix, I.3
Kroner, A.4
Knop, M.5
Lutz, S.6
Müller-Sarnowski, F.7
Uhr, M.8
Bettecken, T.9
Kohli, M.10
-
8
-
-
74049085453
-
Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis
-
Hoppenbrouwers IA, Aulchenko YS, Janssens AC, Ramagopalan SV, Broer L, Kayser M, Ebers GC, Oostra BA, van Duijn CM, Hintzen RQ (2009) Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis. J Hum Genet 54(11):676-680
-
(2009)
J Hum Genet
, vol.54
, Issue.11
, pp. 676-680
-
-
Hoppenbrouwers, I.A.1
Aulchenko, Y.S.2
Janssens, A.C.3
Ramagopalan, S.V.4
Broer, L.5
Kayser, M.6
Ebers, G.C.7
Oostra, B.A.8
Van Duijn, C.M.9
Hintzen, R.Q.10
-
9
-
-
67651152724
-
Replication of KIAA0350, IL2RA, RPL5 and CD58 as multiple sclerosis susceptibility genes in Australians
-
Rubio JP, Stankovich J, Field J, Tubridy N, Marriott M, Chapman C, Bahlo M, Perera D, Johnson LJ, Tait BD, Varney MD, Speed TP, Taylor BV, Foote SJ, Butzkueven H, Kilpatrick TJ (2008) Replication of KIAA0350, IL2RA, RPL5 and CD58 as multiple sclerosis susceptibility genes in Australians. Genes Immun 9 (7):624-630
-
(2008)
Genes Immun
, vol.9
, Issue.7
, pp. 624-630
-
-
Rubio, J.P.1
Stankovich, J.2
Field, J.3
Tubridy, N.4
Marriott, M.5
Chapman, C.6
Bahlo, M.7
Perera, D.8
Johnson, L.J.9
Tait, B.D.10
Varney, M.D.11
Speed, T.P.12
Taylor, B.V.13
Foote, S.J.14
Butzkueven, H.15
Kilpatrick, T.J.16
-
10
-
-
59149093799
-
Variation within the CLEC16A gene shows consistent disease association with both multiple sclerosis and type 1 diabetes in Sardinia
-
Zoledziewska M, Costa G, Pitzalis M, Cocco E, Melis C, Moi ZP, Murru R, Longi R, Morelli et al (2009) Variation within the CLEC16A gene shows consistent disease association with both multiple sclerosis and type 1 diabetes in Sardinia. Genes Immun 10 (1):15-17
-
(2009)
Genes Immun
, vol.10
, Issue.1
, pp. 15-17
-
-
Zoledziewska, M.1
Costa, G.2
Pitzalis, M.3
Cocco, E.4
Melis, C.5
Moi, Z.P.6
Murru, R.7
Morelli, L.R.8
-
11
-
-
77953808270
-
Tag-SNP analysis of the GFI1-EVI5-RPL5-FAM69 risk locus for multiple sclerosis
-
Alcina A, Fernández O, Gonzalez JR, Catalá-Rabasa A, Fedetz M, Ndagire D, Lewa L, Guerrero M, Arnal C, Delgado C et al (2010) Tag-SNP analysis of the GFI1-EVI5-RPL5-FAM69 risk locus for multiple sclerosis. Eur J Hum Genet 18(7):827-831
-
(2010)
Eur J Hum Genet
, vol.18
, Issue.7
, pp. 827-831
-
-
Alcina, A.1
Fernández, O.2
Gonzalez, J.R.3
Catalá-Rabasa, A.4
Fedetz, M.5
Ndagire, D.6
Lewa, L.7
Guerrero, M.8
Arnal, C.9
Delgado, C.10
-
12
-
-
58949099391
-
Genomewide association of susceptibility and clinical phenotype in multiple sclerosis
-
Baranzini SE, Wong J, Gibson A, Galwey N, Naegelin BF, Radue EW, Linbdberg R, Uitdehaag B, Johnson M et al (2009) Genomewide association of susceptibility and clinical phenotype in multiple sclerosis. Human Mol Gen 18(4):767-777
-
(2009)
Human Mol Gen
, vol.18
, Issue.4
, pp. 767-777
-
-
Baranzini, S.E.1
Wong, J.2
Gibson, A.3
Galwey, N.4
Naegelin, B.F.5
Radue, E.W.6
Linbdberg, R.7
Uitdehaag, B.8
Johnson, M.9
-
13
-
-
55849139823
-
Identification of a novel risk locus for multiple sclerosis at 13q31.3 by a pooled genome-wide scan of 500,000 single nucleotide polymorphisms
-
BiomarkerMS Study Group
-
Comabella M, Craig DW, Camiña-Tato M, Morcillo C, Lopez C, Navarro A, Rio J, BiomarkerMS Study Group, Montalban X, Martin R (2008) Identification of a novel risk locus for multiple sclerosis at 13q31.3 by a pooled genome-wide scan of 500,000 single nucleotide polymorphisms. PLoS One 3(10):e3490
-
(2008)
PLoS One
, vol.3
, Issue.10
-
-
Comabella, M.1
Craig, D.W.2
Camiña-Tato, M.3
Morcillo, C.4
Lopez, C.5
Navarro, A.6
Rio, J.7
Montalban, X.8
Martin, R.9
-
14
-
-
59249087219
-
IL2RA/CD25 gene polymorphisms: Uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D)
-
Alcina A, Fedetz M, Ndagire D, Fernández O, Leyva L, Guerrero M, Abad-Grau MM, Arnal C, Delgado C, Lucas M, Izquierdo G, Matesanz F (2009) IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D). PLoS One 4(1):e4137
-
(2009)
PLoS One
, vol.4
, Issue.1
-
-
Alcina, A.1
Fedetz, M.2
Ndagire, D.3
Fernández, O.4
Leyva, L.5
Guerrero, M.6
Abad-Grau, M.M.7
Arnal, C.8
Delgado, C.9
Lucas, M.10
Izquierdo, G.11
Matesanz, F.12
-
15
-
-
58949100205
-
IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production
-
Maier LM, Lowe CE, Cooper J, Downes K, Anderson DE, Severson C, Clark PM, Healy B, Walker N, Aubin C et al (2009) IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production. PloS Genet 5(1):e1000322
-
(2009)
PloS Genet
, vol.5
, Issue.1
-
-
Maier, L.M.1
Lowe, C.E.2
Cooper, J.3
Downes, K.4
Anderson, D.E.5
Severson, C.6
Clark, P.M.7
Healy, B.8
Walker, N.9
Aubin, C.10
-
16
-
-
56749098072
-
Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis
-
Aulchenko YS, Hoppenbrouwers IA, Ramagopalan SV, Broer L, Jafari N, Hillert J, Link J, Lundström W, Greiner E, Dessa Sadovnick A et al (2008) Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis. Nat Genet 40(12):1402-1403
-
(2008)
Nat Genet
, vol.40
, Issue.12
, pp. 1402-1403
-
-
Aulchenko, Y.S.1
Hoppenbrouwers, I.A.2
Ramagopalan, S.V.3
Broer, L.4
Jafari, N.5
Hillert, J.6
Link, J.7
Lundström, W.8
Greiner, E.9
Dessa Sadovnick, A.10
-
17
-
-
45249112573
-
Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations
-
Kristjansdottir G, Sandling JK, Bonetti A, Roos IM, Milani L, Wang C, Gustafsdottir SM, Sigurdsson S, Lundmark A, Tienari PJ et al (2008) Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations. J Med Gent 45(6):362-369
-
(2008)
J Med Gent
, vol.45
, Issue.6
, pp. 362-369
-
-
Kristjansdottir, G.1
Sandling, J.K.2
Bonetti, A.3
Roos, I.M.4
Milani, L.5
Wang, C.6
Gustafsdottir, S.M.7
Sigurdsson, S.8
Lundmark, A.9
Tienari, P.J.10
-
18
-
-
44849138797
-
EVI5 is a risk gene for multiple sclerosis
-
Hoppenbrouwers IA, Aulchenko YS, Ebers GC, Ramagopalan SV, Oostra BA, van Duijn CM, Hintzen RQ (2008) EVI5 is a risk gene for multiple sclerosis. Genes Immun 9(4):334-337
-
(2008)
Genes Immun
, vol.9
, Issue.4
, pp. 334-337
-
-
Hoppenbrouwers, I.A.1
Aulchenko, Y.S.2
Ebers, G.C.3
Ramagopalan, S.V.4
Oostra, B.A.5
Van Duijn, C.M.6
Hintzen, R.Q.7
-
19
-
-
59149093148
-
The expanding genetic overlap between multiple sclerosis and type I diabetes
-
International Multiple Sclerosis Genetics Consortium (IMSGC)
-
International Multiple Sclerosis Genetics Consortium (IMSGC) (2009) The expanding genetic overlap between multiple sclerosis and type I diabetes. Genes Immun 10(1):11-14
-
(2009)
Genes Immun
, vol.10
, Issue.1
, pp. 11-14
-
-
-
20
-
-
77956333737
-
Multiple sclerosis susceptibility-associated SNPs do not influence disease severity measures in a cohort of Australian MS patients
-
Jensen CJ, Stankovich J, Van der Walt A, Bahlo M, Tylor BV, van der Mei I, Foote SJ, Sigurdsson S, Lundmark A, Tienari PJ et al (2010) Multiple sclerosis susceptibility-associated SNPs do not influence disease severity measures in a cohort of Australian MS patients. PLOS one 5(4):1-7
-
(2010)
PLOS One
, vol.5
, Issue.4
, pp. 1-7
-
-
Jensen, C.J.1
Stankovich, J.2
Van Der Walt, A.3
Bahlo, M.4
Tylor, B.V.5
Van Der Mei, I.6
Foote, S.J.7
Sigurdsson, S.8
Lundmark, A.9
Tienari, P.J.10
-
21
-
-
58849146101
-
Genotype-phenotype correlations in multiple sclerosis: HLA genes influence disease severity inferred by 1HMR spectroscopy and MRO measures
-
Okuda DT, Srinivasan R, Oksenberg JR, Goodin DS, Baranzini E, Beheshtian A, Waubant E, Zamvil SS, Leppert D, Qualley P et al (2009) Genotype-phenotype correlations in multiple sclerosis: HLA genes influence disease severity inferred by 1HMR spectroscopy and MRO measures. Brain 132(1):250-259
-
(2009)
Brain
, vol.132
, Issue.1
, pp. 250-259
-
-
Okuda, D.T.1
Srinivasan, R.2
Oksenberg, J.R.3
Goodin, D.S.4
Baranzini, E.5
Beheshtian, A.6
Waubant, E.7
Zamvil, S.S.8
Leppert, D.9
Qualley, P.10
-
22
-
-
51249089462
-
HLADRB1*15 allele influences the later course of relapsing remitting multiple sclerosis
-
Cournu-Rebeix I, Genin E, Leray E, Babron MC, Cohen J, Gout C, Alizadeh M, Perdry H, Semana G, Brassat D et al (2008) HLADRB1*15 allele influences the later course of relapsing remitting multiple sclerosis. Genes Immun 9(6):570-574
-
(2008)
Genes Immun
, vol.9
, Issue.6
, pp. 570-574
-
-
Cournu-Rebeix, I.1
Genin, E.2
Leray, E.3
Babron, M.C.4
Cohen, J.5
Gout, C.6
Alizadeh, M.7
Perdry, H.8
Semana, G.9
Brassat, D.10
-
23
-
-
0034955141
-
Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the diagnosis of multiple sclerosis
-
McDonald WI, Compston A, Edan G, Goodkin D, Hartung HP, Lublin FD, Mc Farland HF, Paty DW, Polman CH, Reingold SC et al (2001) Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol 50(1):121-127
-
(2001)
Ann Neurol
, vol.50
, Issue.1
, pp. 121-127
-
-
McDonald, W.I.1
Compston, A.2
Edan, G.3
Goodkin, D.4
Hartung, H.P.5
Lublin, F.D.6
Mc Farland, H.F.7
Paty, D.W.8
Polman, C.H.9
Reingold, S.C.10
-
24
-
-
33244466021
-
Natural history of multiple sclerosis: A unifying concept
-
Confavreux C, Vukusic S (2006) Natural history of multiple sclerosis: a unifying concept. Brain 129(3):606-661
-
(2006)
Brain
, vol.129
, Issue.3
, pp. 606-661
-
-
Confavreux, C.1
Vukusic, S.2
-
25
-
-
23844472247
-
KORA-gen-resource for population genetics, controls and a broad spectrum of disease phenotypes
-
MONICA/KORA Study Group Review
-
Wichmann HE, Gieger C, Illig T, MONICA/KORA Study Group (2005) KORA-gen-resource for population genetics, controls and a broad spectrum of disease phenotypes. Gesundheitswesen 67 (Suppl 1):S26-S30, Review
-
(2005)
Gesundheitswesen
, vol.67
, Issue.SUPPL. 1
-
-
Wichmann, H.E.1
Gieger, C.2
Illig, T.3
-
26
-
-
0025066941
-
More powerful procedures for multiple significance testing
-
Hochberg Y, Benjamini Y (1990) More powerful procedures for multiple significance testing. Stat Med 9(7):811-818
-
(1990)
Stat Med
, vol.9
, Issue.7
, pp. 811-818
-
-
Hochberg, Y.1
Benjamini, Y.2
-
27
-
-
79952282726
-
Replication of top markers of a genome-wide association study in multiple sclerosis in Spain
-
Cavanillas ML, Fernández O, Comabella M, Alcina A, Fedetz M, Izquierdo G, Lucas M, Cenit MC, Arroyo R, Vandenbroeck K et al (2010) Replication of top markers of a genome-wide association study in multiple sclerosis in Spain. Genes Immun 12(2):110-115
-
(2010)
Genes Immun
, vol.12
, Issue.2
, pp. 110-115
-
-
Cavanillas, M.L.1
Fernández, O.2
Comabella, M.3
Alcina, A.4
Fedetz, M.5
Izquierdo, G.6
Lucas, M.7
Cenit, M.C.8
Arroyo, R.9
Vandenbroeck, K.10
-
28
-
-
42949095543
-
Discovery of a lysophospholipid acyltransferase family essential for membrane asymmetry and diversity
-
Hishikawa D, Shindou H, Kobayashi S, Nakanishi H, Taguchi R, Shimizu T (2008) Discovery of a lysophospholipid acyltransferase family essential for membrane asymmetry and diversity. Proc Natl Acad Sci U S A 105(8):2830-2835
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.8
, pp. 2830-2835
-
-
Hishikawa, D.1
Shindou, H.2
Kobayashi, S.3
Nakanishi, H.4
Taguchi, R.5
Shimizu, T.6
-
29
-
-
33847230623
-
No gene is an island: The flip-flop phenomenon
-
Lin PI, Vance JM, Pericak-Vance MA, Martin ER (2007) No gene is an island: the flip-flop phenomenon. Am J Hum Genet 80 (3):531-538
-
(2007)
Am J Hum Genet
, vol.80
, Issue.3
, pp. 531-538
-
-
Lin, P.I.1
Vance, J.M.2
Pericak-Vance, M.A.3
Martin, E.R.4
-
30
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium
-
Wellcome Trust Case Control Consortium (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447(7145):661-678
-
(2007)
Nature
, vol.447
, Issue.7145
, pp. 661-678
-
-
-
31
-
-
0035053942
-
HLA-DRB1 and disease outcome in multiple sclerosis
-
Weatherby SJ, Thomson W, Pepper L, Donn R, Worthington J, Mann CL, Davis MB, Fryer AA, Boggild MD, Young CA et al (2001) HLA-DRB1 and disease outcome in multiple sclerosis. J Neurol 248(4):304-310
-
(2001)
J Neurol
, vol.248
, Issue.4
, pp. 304-310
-
-
Weatherby, S.J.1
Thomson, W.2
Pepper, L.3
Donn, R.4
Worthington, J.5
Mann, C.L.6
Davis, M.B.7
Fryer, A.A.8
Boggild, M.D.9
Young, C.A.10
-
32
-
-
0033862965
-
HLA-DR15 is associated with lower age at onset in multiple sclerosis
-
Masterman T, Ligers A, Olsson T, Andersson M, Olerup O, Hillert J (2000) HLA-DR15 is associated with lower age at onset in multiple sclerosis. Ann Neurol 48(2):211-219
-
(2000)
Ann Neurol
, vol.48
, Issue.2
, pp. 211-219
-
-
Masterman, T.1
Ligers, A.2
Olsson, T.3
Andersson, M.4
Olerup, O.5
Hillert, J.6
-
33
-
-
0036155101
-
HLA-DR 15 is associated with female sex and younger age at diagnosis in multiple sclerosis
-
Hensiek AE, Sawcer SJ, Feakes R, Deans J, Mander A, Akesson E, Roxburgh R, Coraddu F, Smith S, Compston DA (2002) HLA-DR 15 is associated with female sex and younger age at diagnosis in multiple sclerosis. J Neurol Neurosurg Psychiatry 72(2):184-187
-
(2002)
J Neurol Neurosurg Psychiatry
, vol.72
, Issue.2
, pp. 184-187
-
-
Hensiek, A.E.1
Sawcer, S.J.2
Feakes, R.3
Deans, J.4
Mander, A.5
Akesson, E.6
Roxburgh, R.7
Coraddu, F.8
Smith, S.9
Compston, D.A.10
-
34
-
-
34547223570
-
The impact of HLA-A and DRB1 on age at onset, disease course and severity in Scandinavian multiple sclerosis patients
-
Smestad C, Brynedal B, Jonasdottir G, Lorentzen AR, Mastermann T, Akesson E, Spurkland A, Lie BA, Palmgren J et al (2007) The impact of HLA-A and DRB1 on age at onset, disease course and severity in Scandinavian multiple sclerosis patients. Eur J Neurol 14(8):535-840
-
(2007)
Eur J Neurol
, vol.14
, Issue.8
, pp. 535-840
-
-
Smestad, C.1
Brynedal, B.2
Jonasdottir, G.3
Lorentzen, A.R.4
Mastermann, T.5
Akesson, E.6
Spurkland, A.7
Lie, B.A.8
Palmgren, J.9
-
35
-
-
33947274768
-
Association of the interleukin 2 receptor alpha (IL-2Ralpha)/CD25 gene region with Graves' disease using a multilocus test and tag SNPs
-
Brand OJ, Lowe CE, Heward JM, Franklyn JA, Cooper JD, Todd JA, Gough SC (2007) Association of the interleukin 2 receptor alpha (IL-2Ralpha)/CD25 gene region with Graves' disease using a multilocus test and tag SNPs. Clin Endocrinol 66(4):508-512
-
(2007)
Clin Endocrinol
, vol.66
, Issue.4
, pp. 508-512
-
-
Brand, O.J.1
Lowe, C.E.2
Heward, J.M.3
Franklyn, J.A.4
Cooper, J.D.5
Todd, J.A.6
Gough, S.C.7
-
36
-
-
51749098572
-
Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency
-
Skinningsrud B, Husebye ES, Pearce SH, McDonald DO, Brandal K, Wolff AB, Løvås K, Egeland T, Undlien DE (2008) Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency. J Clin Endocrinol Metab 93(9):3310-3317
-
(2008)
J Clin Endocrinol Metab
, vol.93
, Issue.9
, pp. 3310-3317
-
-
Skinningsrud, B.1
Husebye, E.S.2
Pearce, S.H.3
McDonald, D.O.4
Brandal, K.5
Wolff, A.B.6
Løvås, K.7
Egeland, T.8
Undlien, D.E.9
|