Plasma disposition and tissue depletion of chlortetracycline in the food producing animals, chickens for fattening

Food and Chemical Toxicology

Volumn 50, Issue 8, 2012, Pages 2714-2721

  Anadón, Arturo ^a   Gamboa, Felipe ^a   Martínez, María Aránzazu ^a   Castellano, Víctor ^a   Martínez, Marta ^a   Ares, Irma ^a   Ramos, Eva ^a   Suarez, Frank H ^a   Martínez Larrañaga, María Rosa ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Chickens for fattening; Chlortetracycline; Plasma and tissue depletion; Withdrawal time

Indexed keywords

4 EPICHLORTETRACYCLINE; CHLORTETRACYCLINE; TETRACYCLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHICKEN; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DISPOSITION; DRUG TISSUE LEVEL; KIDNEY; LIVER; MALE; MAXIMUM ALLOWABLE CONCENTRATION; MUSCLE; NONHUMAN; PLASMA HALF LIFE; SINGLE DRUG DOSE;

ANIMALS; ANTI-BACTERIAL AGENTS; BIOLOGICAL AVAILABILITY; CHICKENS; CHLORTETRACYCLINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; TISSUE DISTRIBUTION;

ANIMALIA; GALLUS GALLUS;

EID: 84862687898     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.05.007     Document Type: Article

References (45)

1. Agwuh K.N., MacGowan A. Pharmacokinetics and pharmacodynamics of the tetracyclines including glycylcyclines. J. Antimicrob. Chemother. 2006, 58:256-265.
2. Anadón A., Martínez-Larrañaga M.R., Díaz M.J. Pharmacokinetics of tetracycline in chickens after intravenous administration. Poultry Sci. 1985, 64:2273-2279.
3. Anadón A., Martínez-Larrañaga M.R., Díaz M.J., Bringas P., Fernandez M.C., Fernandez-Cruz M.L., Iturbe J., Martínez M.A. Pharmacokinetics of doxycycline in broiler chickens. Avian Pathol. 1994, 23:79-90.
4. Anadón A., Suarez F.H., Martínez M.A., Castellano V., Martínez M., Ares I., Ramos E., Gamboa F., Martínez-Larrañaga M.A. Plasma disposition and tissue depletion of difloxacin and its metabolite sarafloxacin in the food producing animals, chicken for fattening. Food Chem. Toxicol. 2011, 49:441-449.
5. Barza M., Brown R.B., Shanks C., Gamble G., Weinstein L. Relation between lipophilicity and pharmacological behavior of minocycline, doxycycline, tetracycline and oxytetracycline in dogs. Antimicrob. Agents Chemother. 1975, 8:713-720.
6. Bradley B.D., Allen E.H., Showalter D.H., Colaianne J.J. Comparative pharmacokinetics of chlortetracycline in milk-fed versus conventionally fed calves. J. Vet. Pharmacol. Ther. 1982, 5:267-278.
7. Boxenbaum H. Pharmacokinetics tricks and traps: flip-flop models. J. Pharm. Pharmaceut. Sci. 1998, 1(3):90-91.
8. Burch, D.G.S., Valks, M., 2002. Comparison of minimal inhibitory concentrations (MIC) against chicken mycoplasma of tiamulin and other antimicrobials and their concentrations in the blood. In: Proceedings of the XII International Congress of the World Veterinary Poultry Association, El Cairo, Egypt, p. 322.
9. Burgess D.S., Frei C.R., Lewis J.S., Fiebelkorn K.R., Jorgensen J.H. The contribution of pharmacokinetic-pharmacodynamic modeling with Monte Carlo simulation of the development of susceptibility breakpoints for Neisseria meningitidis. Clin. Microbiol. Infect. 2006, 13(1):33-39.
10. Cerda R.O., Giacoboni G.I., Xavier J.A., Sansalone P.L., Landoni M.F. In vitro antibiotic susceptibility of field isolates of Mycoplasma synoviae in Argentina. Avian Dis. 2002, 46:215-218.
11. Chopra I., Roberts M. Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance. Microbiol. Mol. Biol. Rev. 2001, 62(2):232-260.
12. Craig W.A. Pharmacokinetic/pharmacodynamics parameters: rationale for antibacterial dosing of mice and men. Clin. Infect. Dis. 1998, 26:1-10.
13. Cunha B.A., Domenico P., Cunha C.B. Pharmacodymanics of doxycycline. Clin. Microbiol. Infect. 2000, 6(5):270-273.
14. Drusano G.L. Prevention of resistance: a goal for dose selection for antimicrobial agents. Clin. Infect. Dis. 2003, 36:S42-S50.
15. Dyer D.C. Pharmacokinetics of chlortetracycline in the turkey: evaluation of biliary excretion. Am. J. Vet. Res. 1988, 49(1):36-37.
16. EMEA (The European Agency for the Evaluation of Medicinal Products), 1995. Oxytetracycline, Tetracycline, Chlortetracycline. Summary Report. Committee for Veterinary Medicinal Products. EMEA/MRL/023/95, London, UK.
17. EMEA (The European Agency for the Evaluation of Medicinal Products), 1998. Guideline on Validation of Analytical Procedures: Methodology (VICH GL2). CVMP/VICH/591/98-FINAL, London, UK. pp. 1-10.
18. EMEA (The European Agency for the Evaluation of Medicinal Products), 2002. Updated Application Software Relating to Note for Guidance on Approach Towards Harmonisation of Withdrawal Periods for Meat. EMEA/CVMP/563/02, London, UK.
19. Eisner H.J., Wulf R.J. The metabolic fate of chlortetracycline and some comparisons with other tetracyclines. J. Pharmacol. Exp. Ther. 1963, 142:122-131.
20. Finch R.G. Tetracyclines. Antibiotic and Chemotherapy 1997, 469-484. Churchill Livingstone Ltd., New York. F. O'Grady, H.P. Lambert, R.G. Finch, D. Greenwood (Eds.).
21. Gamboa, F., Suarez, F.H., Caballero, V., Martínez, M.A., Castellano, V., Ares, I., Torres, A., Martínez-Larrañaga, M.R., Anadón, A., 2009. Pharmacokinetics of chlortetracycline following intravenous administration in healthy chickens. 11th International EAVPT Congress. Leipzig (Germany), July 12-16. J. Vet. Pharmacol. Ther. 32 (Suppl. 1), 144-145.
22. Hardee G.E., Baggot J.D. Development and formulations of veterinary dosage forms. Drugs in the Pharmaceutical Sciences 1998, 100-103. Marcel Dekker Inc., New York. second ed. G.E. Hardee, J.D. Baggot (Eds.).
23. Huang T., Lin T., Wu C. Antimicrobial susceptibility and resistance of chicken Escherichia coli, Salmonella spp., and Pasteurella multocida isolates. Avian Dis. 2009, 53:89-93.
24. Kelly R.G., Kanegis L.A. Tissue distribution of tetracycline and chlortetracycline in the dog. Toxicol. Appl. Pharmacol. 1967, 11:114-120.
25. Kilroy C.R., Hall W.F., Bane D.P., Bevill R.F., Koritz G.D. Chlortetracycline in swine-bioavailability and pharmacokinetics in fasted and fed pigs. J. Vet. Pharmacol. Ther. 1990, 13:49-58.
26. Kunin C.M., Finland M. Clinical Pharmacology of the tetracycline antibiotics. Clin. Pharmacol. Ther. 1961, 2:51-69.
27. McCormick J.R.D., Fox S.M., Smith L.L., Bitler B.A., Reichenthal J., Origoni V.E., Muller W.H., Winterbottom R., Doerschuk A.P. Studies of the reversible epimerization occurring in the tetracycline family. The preparation, properties and proof of structure of some 4-epi-tetracyclines. J. Am. Chem. Soc. 1957, 79(11):2849-2858.
28. Mouton J.W. Impact of pharmacodynamics on breakpoint selection for susceptibility testing. Infect. Dis. Clin. North Am. 2003, 17:579-598.
29. Neuvonen P.J. Interactions with the absorption of tetracyclines. Drugs 1976, 11:45-54.
30. Nielsen P., Gyrd-Hansen N. Bioavailability of oxytetracycline, tetracycline and chlortetracycline after oral administration to fed and fasted pigs. J. Vet. Pharmacol. Ther. 1996, 19:305-311.
31. Piddock L.J., Griggs D., Johnson M.M., Ricci V., Elviss N.C., Williams L.K., Jorgensen F., Chisholm S.A., Lawson A.J., Swift C., Humphrey T.J., Owen R.J. Persistence of Campylobacter species antibiotic resistance and mechanisms of tetracycline resistance in poultry flocks treated with chlortetracycline. J. Antimicrob. Chemother. 2008, 62:303-315.
32. Pollet R.A., Glatz C.E., Dyer D.C., Barnes H.J. Pharmacokinetics of chlortetracycline potentiation with citric acid in chicken. Am. J. Vet. Res. 1983, 44:1718-1721.
33. Pollet R.A., Glatz C.E., Dyer D.C. The pharmacokinetics of chlortetracycline orally administered to turkeys: influence of citric acid and Pasteurella multocida infection. J. Pharmacokinet. Biopharm. 1985, 13(3):243-264.
34. Reinbold J.B., Coetzee J.F., Gehring R., Havel J.A., Hollis L.C., Olson K.C., Apley M.D. Plasma pharmacokinetics of oral chlortetracycline in group fed, ruminating, Holstein steers in a feedlot setting. J. Vet. Pharmacol. Ther. 2009, 33:76-83.
35. Sengelov G., Halling-Sorensen B., Aarestrup F. Susceptibility of Escherichia coli and Enterococcus faecium isolated from pigs and broiler chickens to tetracycline resistance determinates in E. coli from food animals. Vet. Microbiol. 2003, 95:91-101.
36. Toutain P.L., Del Castillo J.R.E., Bousquet-Mélou A. The pharmacokinetic-pharmacodynamic approach to a rational dosage regimen for antibiotics. Res. Vet. Sci. 2002, 73:105-114.
37. Toutain P.L. Antibiotic treatment of animals. A different approach to rational dosing. Vet. J. 2003, 165:98-100.
38. Toutain P.L., Bousquet-Mélou A., Martínez M. AUC/MIC: a PK/PD index for antibiotics with a time dimension or simply a dimensionless scoring factor?. J. Antimicrob. Chemother. 2007, 60:1185-1188.
39. Vermeulen B., De Backer P., Remon J.P. Drug administration to poultry. Adv. Drug Delivery Rev. 2002, 54:795-803.
40. Wagner J.G. Fundamentals of Clinical Pharmacokinetics 1975, Drug Intelligence Publications, Hamilton, IL. first ed.
41. Wagner J.G. Linear pharmacokinetic equations allowing direct calculation of many needed pharmacokinetic parameters from the coefficients and exponents of polyexponential equations which have been fitted to the data. J. Pharmacokinet. Biopharm. 1976, 4:443-467.
42. Walsh J.R., Walker L.V., Webber J.J. Determination of tetracyclines in bovine and porcine muscle by high-performance liquid chromatography using solid-phase extraction. J. Chromatogr. 1992, 596:211-216.
43. Welling P.G., Koch P.A., Lau C.C., Craig W.A. Bioavailability of tetracycline and doxycycline in fasted and nonfasted subject. Antimicrob. Agents Chemother. 1977, 11:462-469.
44. Wu Y., Fassihi R. Stability of metronidazole, tetracycline HCl and famotidine alone and in combination. Int. J. Pharm. 2005, 290:1-13.
45. Yamaoka K., Nakagawa T., Uno T. Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations. J. Pharmacokinet. Biopharm. 1978, 6:165-175.