Inhibition of proliferation of human lung cancer cells by green tea catechins is mediated by upregulation of let-7

Experimental and Therapeutic Medicine

Volumn 4, Issue 2, 2012, Pages 267-272

  Zhong, Zhiwei ^a   Dong, Zhuo ^a   Yang, Lihua ^a   Chen, Xiaoqiang ^b   Gong, Zhaohui ^a  

^a NINGBO UNIVERSITY   (China)

^b Hangzhou Tea Research Institute   (China)

Author keywords

Anticancer; C MYC; Let 7; LIN 28; MicroRNA; Tea catechin

Indexed keywords

CATECHIN; GREEN TEA EXTRACT; MESSENGER RNA; MICRORNA; PROTEIN LET 7A; PROTEIN LET 7G; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOGENESIS; CELL ASSAY; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG CANCER; ONCOGENE C MYC; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

EID: 84862686712     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2012.580     Document Type: Article

References (38)

1. Siegel R, Ward E, Brawley O and Jemal A: Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin 61: 212-236, 2011.
2. Rodriguez E and Lilenbaum RC: Small cell lung cancer: past, present, and future. Curr Oncol Rep 12: 327-334, 2010.
3. Osada H and Takahashi T: let-7 and miR-17-92: small-sized major players in lung cancer development. Cancer Sci 102: 9-17, 2011.
4. Bandi N, Zbinden S, Gugger M, et al: miR-15a and miR-16 are implicated in cell cycle regulation in a Rb-dependent manner and are frequently deleted or down-regulated in non-small cell lung cancer. Cancer Res 69: 5553-5559, 2009.
5. Wang QZ, Xu W, Habib N and Xu R: Potential uses of microRNA in lung cancer diagnosis, prognosis, and therapy. Curr Cancer Drug Targets 9: 572-594, 2009.
6. Cimmino A, Calin GA, Fabbri M, et al: miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA 102: 13944-13949, 2005.
7. Valeri N, Gasparini P, Fabbri M, et al: Modulation of mismatch repair and genomic stability by miR-155. Proc Natl Acad Sci USA 107: 6982-6987, 2010.
8. Liu X, Sempere LF, Ouyang H, et al: MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors. J Clin Invest 120: 1298-1309, 2010.
9. Zhu S, Wu H, Wu F, Nie D, Sheng S and Mo YY: MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res 18: 350-359, 2008.
10. Johnson CD, Esquela-Kerscher A, Stefani G, et al: The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res 67: 7713-7722, 2007.
11. Johnson SM, Grosshans H, Shingara J, et al: RAS is regulated by the let-7 microRNA family. Cell 120: 635-647, 2005.
12. He XY, Chen JX, Zhang Z, Li CL, Peng QL and Peng HM: The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice. J Cancer Res Clin Oncol 136: 1023-1028, 2010.
13. Wong TS, Man OY, Tsang CM, et al: MicroRNA let-7 suppresses nasopharyngeal carcinoma cell proliferation through downregulating c-Myc expression. J Cancer Res Clin Oncol 137: 415-422, 2011.
14. Lan FF, Wang H, Chen YC, et al: Hsa-let-7g inhibits proliferation of hepatocellular carcinoma cells by downregulation of c-Myc and upregulation of p16(INK4A). Int J Cancer 128: 319-331, 2011.
15. Dangi-Garimella S, Yun J, Eves EM, et al: Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7. EMBO J 28: 347-358, 2009.
16. Balentine DA, Wiseman SA and Bouwens LC: The chemistry of tea flavonoids. Crit Rev Food Sci Nutr 37: 693-704, 1997.
17. Dube A, Nicolazzo JA and Larson I: Chitosan nanoparticles enhance the intestinal absorption of the green tea catechins (+)-catechin and (-)-epigallocatechin gallate. Eur J Pharm Sci 41: 219-225, 2010.
18. Higdon JV and Frei B: Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions. Crit Rev Food Sci Nutr 43: 89-143, 2003.
19. Fujiki H, Yoshizawa S, Horiuchi T, et al: Anticarcinogenic effects of (-)-epigallocatechin gallate. Prev Med 21: 503-509, 1992.
20. Liao S, Umekita Y, Guo J, Kokontis JM and Hiipakka RA: Growth inhibition and regression of human prostate and breast tumors in athymic mice by tea epigallocatechin gallate. Cancer Lett 96: 239-243, 1995.
21. Hirose M, Mizoguchi Y, Yaono M, Tanaka H, Yamaguchi T and Shirai T: Effects of green tea catechins on the progression or late promotion stage of mammary gland carcinogenesis in female Sprague-Dawley rats pretreated with 7,12-dimethylbenz(a)anthracene. Cancer Lett 112: 141-147, 1997.
22. Fix LN, Shah M, Efferth T, Farwell MA and Zhang B: MicroRNA expression profile of MCF-7 human breast cancer cells and the effect of green tea polyphenon-60. Cancer Genomics Proteomics 7: 261-277, 2010.
23. Tsang WP and Kwok TT: Epigallocatechin gallate up-regulation of miR-16 and induction of apoptosis in human cancer cells. J Nutr Biochem 21: 140-146, 2008.
24. Kumar MS, Erkeland SJ, Pester RE, Chen CY, Ebert MS, Sharp PA and Jacks T: Suppression of non-small cell lung tumor development by the let-7 microRNA family. Proc Natl Acad Sci USA 105: 3903-3908, 2008.
25. Esquela-Kerscher A, Trang P, Wiggins JF, et al: The let-7 microRNA reduces tumor growth in mouse models of lung cancer. Cell Cycle 7: 759-764, 2008.
26. He X, Duan C, Chen J, Ou-Yang X, Zhang Z, Li C and Peng H: Let-7a elevates p21(WAF1) levels by targeting of NIRF and suppresses the growth of A549 lung cancer cells. FEBS Lett 583: 3501-3507, 2009.
27. Izzotti A, Calin GA, Arrigo P, Steele VE, Croce CM and De Flora S: Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke. FASEB J 23: 806-812, 2009.
28. Izzotti A, Calin GA, Steele VE, Cartiglia C, Longobardi M, Croce CM and De Flora S: Chemoprevention of cigarette smoke-induced alterations of microRNA expression in rat lungs. Cancer Prev Res (Phila) 3: 62-72, 2010.
29. Manna S, Mukherjee S, Roy A, Das S and Panda CK: Tea polyphenols can restrict benzo[a]pyrene-induced lung carcinogenesis by altered expression of p53-associated genes and H-ras, c-myc and cyclin D1. J Nutr Biochem 20: 337-349, 2009.
30. Yang CS and Wang X: Green tea and cancer prevention. Nutr Cancer 62: 931-937, 2010.
31. Babich H, Krupka ME, Nissim HA and Zuckerbraun HL: Differential in vitro cytotoxicity of (-)-epicatechin gallate (ECG) to cancer and normal cells from the human oral cavity. Toxicol In Vitro 19: 231-242, 2005.
32. Yang CS, Wang X, Lu G and Picinich SC: Cancer prevention by tea: animal studies, molecular mechanisms and human relevance. Nat Rev Cancer 9: 429-439, 2009.
33. Yang N, Coukos G and Zhang L: MicroRNA epigenetic alterations in human cancer: one step forward in diagnosis and treatment. Int J Cancer 122: 963-968, 2008.
34. Ramachandran R, Fausett BV and Goldman D: Ascl1a regulates Müller glia dedifferentiation and retinal regeneration through a Lin-28-dependent, let-7 microRNA signalling pathway. Nat Cell Biol 12: 1101-1107, 2010.
35. Li Y, VandenBoom TG II, Kong D, Wang Z, Ali S, Philip PA and Sarkar FH: Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. Cancer Res 69: 6704-6712, 2009.
36. Sun Q, Cong R, Yan H, et al: Genistein inhibits growth of human uveal melanoma cells and affects microRNA-27a and target gene expression. Oncol Rep 22: 563-567, 2009.
37. Sun M, Estrov Z, Ji Y, Coombes KR, Harris DH and Kurzrock R: Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells. Mol Cancer Ther 7: 464-473, 2008.
38. * signaling pathway. Oncol Rep 24: 1217-1223, 2010