Substrate specificity of the OqxAB multidrug resistance pump in Escherichia coli and selected enteric bacteria

Journal of Antimicrobial Chemotherapy

Volumn 60, Issue 1, 2007, Pages 145-147

  Hansen, Lars Hestbjerg ^a   Jensen, Lars Bogø ^b   Sørensen, Heidi Iskou ^a,b   Sørensen, Søren Johannes ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Antibiotic resistance; Detergents; Disinfectants; Growth promoters; Multidrug efflux pumps

Indexed keywords

ACRIFLAVINE; ANTIBIOTIC AGENT; BENZALKONIUM CHLORIDE; CARBADOX; CETRIMIDE; CHLORAMPHENICOL; CHLORHEXIDINE; CIPROFLOXACIN; DETERGENT; DISINFECTANT AGENT; ERYTHROMYCIN; FLUMEQUINE; MITOMYCIN C; NALIDIXIC ACID; NORFLOXACIN; OLAQUINDOX; RIFAMPICIN; TETRACYCLINE; TRICLOSAN; TRIMETHOPRIM;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DILUTION; ENTEROBACTER AEROGENES; ENTEROBACTERIACEAE; ENZYME SPECIFICITY; ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE; KLUYVERA; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; OPERON; PLASMID; SALMONELLA TYPHIMURIUM;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS, LOCAL; BACTERIAL PROTEINS; DETERGENTS; DISINFECTANTS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ENTEROBACTERIACEAE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE TRANSFER, HORIZONTAL; GROWTH SUBSTANCES; MICROBIAL SENSITIVITY TESTS; PLASMIDS; QUINOXALINES; SUBSTRATE SPECIFICITY;

EID: 34447547677     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkm167     Document Type: Article

References (12)

1. Wegener HC. Antibiotics in animal feed and their role in resistance development. Curr Opin Microbiol 2003; 6: 439-45.
2. Hansen LH, Sørensen SJ, Jøorgensen HS et al. The prevalence of the OqxAB multidrug efflux pump amongst olaquindox-resistant Escherichia coli in pigs. Microb Drug Resist 2005; 11: 378-82.
3. Sørensen AH, Hansen LH, Johannesen E et al. Conjugative plasmid conferring resistance to olaquindox. Antimicrob Agents Chemother 2003; 47: 798-9.
4. Hansen LH, Johannesen E, Burmolle M et al. Plasmid-encoded multidrug efflux pump conferring resistance to olaquindox in Escherichia coli. Antimicrob Agents Chemother 2004; 48: 3332-7.
5. Miller JH. Experiments in Molecular Genetics. Cold Spring Harbor: Cold Spring Harbor Laboratory Press, 1972.
6. Olsen JE, Brown DJ, Thomsen LE et al. Differences in the carriage and the ability to utilize the serotype associated virulence plasmid in strains of Salmonella enterica serotype Typhimurium investigated by use of a self-transferable virulence plasmid, pOG669. Microb Pathog 2004; 36: 337-47.
7. Burmølie M, Hansen LH, Sørensen SJ. Use of a whole-cell biosensor and flow cytometry to detect AHL production by an indigenous soil community during decomposition of litter. Microb Ecol 2005; 50 221-9.
8. Li XZ, Nikaido H. Efflux-mediated drug resistance in bacteria. Drugs 2004; 64: 159-204.
9. Campbell L, Zirwas MJ. Triclosan. Dermatitis 2006; 17: 204-7.
10. Fralick JA. Evidence that TolC is required for functioning of the Mar/AcrAB efflux pump of Escherichia coli. J Bacteriol 1996; 178 5803-5.
11. Altschul SF, Madden TL, Schaffer AA et al. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Res 1997; 25: 3389-402.
12. NPS-1, and a tripartite antibiotic efflux system of the resistance-nodulation-division family. Mol Genet Genomics 2003; 268: 570-84.