Evaluation of substrate and inhibitor binding to yeast and human isoprenylcysteine carboxyl methyltransferases (Icmts) using biotinylated benzophenone-containing photoaffinity probes

Biochemical and Biophysical Research Communications

Volumn 423, Issue 1, 2012, Pages 98-103

  Hahne, Kalub ^a,e   Vervacke, Jeffrey S ^b,c   Shrestha, Liza ^d,e   Donelson, James L ^d,e   Gibbs, Richard A ^d,e   Distefano, Mark D ^b,c   Hrycyna, Christine A ^a,e  

^a PURDUE UNIVERSITY   (United States)

^b University of Minnesota   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

^d PURDUE UNIVERSITY   (United States)

^e Purdue University   (United States)

Author keywords

A Factor; Benzophenone; Icmt; Methyltransferase; Photocrosslinking; Ste14p

Indexed keywords

BENZOPHENONE; FACTOR A; N ACETYL S FARNESYL L CYSTEINE; PHEROMONE; PROTEIN S ISOPRENYLCYSTEINE O METHYLTRANSFERASE; UNCLASSIFIED DRUG;

ALKYLATION; AMINO ACID COMPOSITION; ARTICLE; BINDING SITE; BIOTINYLATION; CROSS LINKING; ENZYME ANALYSIS; ENZYME BINDING; ENZYME SPECIFICITY; HUMAN; MOLECULAR PROBE; NONHUMAN; PHOTOACTIVATION; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

ACETYLCYSTEINE; BENZOPHENONES; BINDING SITES; BIOTINYLATION; ENZYME INHIBITORS; HUMANS; PEPTIDES; PHOTOAFFINITY LABELS; PROTEIN METHYLTRANSFERASES; SACCHAROMYCES CEREVISIAE; SUBSTRATE SPECIFICITY;

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 84862654302     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.05.089     Document Type: Article

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