Bacteria on external fixators: Which prep is best?

Journal of Trauma and Acute Care Surgery

Volumn 72, Issue 3, 2012, Pages 760-764

  Stinner, Daniel J ^b   Beltran, Michael J ^a   Masini, Brendan D ^a   Wenke, Joseph C ^b   Hsu, Joseph R ^a  

^a BROOKE ARMY MEDICAL CENTER   (United States)

^b US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

Author keywords

External fixation; Infection; Invasive distraction; Surgical prep; Surgical site infection

Indexed keywords

CHLORHEXIDINE GLUCONATE; POVIDONE IODINE; TOPICAL ANTIINFECTIVE AGENT;

ARTICLE; ASEPSIS; BACTERIAL COUNT; BACTERIUM ADHERENCE; CAMERA; COMPUTER PROGRAM; EXTERNAL FIXATOR; IMAGING SYSTEM; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; EQUIPMENT; FRACTURE; FRACTURE FIXATION; HUMAN; INSTRUMENTATION; ISOLATION AND PURIFICATION; MICROBIOLOGY; RANDOMIZED CONTROLLED TRIAL; STAPHYLOCOCCUS INFECTION; SURGICAL INFECTION;

ANTI-INFECTIVE AGENTS, LOCAL; COLONY COUNT, MICROBIAL; EQUIPMENT CONTAMINATION; EXTERNAL FIXATORS; FRACTURE FIXATION; FRACTURES, BONE; HUMANS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; SURGICAL WOUND INFECTION;

EID: 84862643437     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0b013e31823c97f5     Document Type: Article

References (17)

1. Harris AM, Althausen PL, Kellam J, Bosse MJ, Castillo R; Lower Extremity Assessment Project (LEAP) Study Group. Complications following limb-threatening lower extremity trauma. J Orthop Trauma. 2009;23:1-6.
2. Masini BD, Owens BD, Hsu JR, Wenke JC. Rehospitalization after combat injury. J Trauma. 2011;71(1 suppl):S147-S50.
3. Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. Guidelines for prevention of surgical site infection, 1999: Hospital infection control practices advisory committee. Infect Control Hosp Epidemiol. 1999;20: 250-278.
4. Pape HC, Hildebrand F, Pertschy S, et al. Changes in the management of femoral shaft fractures in polytrauma patients: from early total care to damage control orthopedic surgery. J Trauma. 2002;53:452-462.
5. Sirkin M, Sanders R, DiPasquale T, Herscovici D Jr. A staged protocol for soft tissue management in the treatment of complex pilon fractures. J Orthop Trauma. 1999;13:78-84.
6. Egol KA, Tejwani NC, Capla EL, Wolinsky PL, Koval KJ. Staged management of high-energy proximal tibia fractures (OTA types 41). The results of a prospective, standardized protocol. J Orthop Trauma. 2005;19:448-455.
7. Hak DJ, Wiater PJ, Williams RM, Pierson CL. The effectiveness of standard povidone iodine surgical preparation in decontaminating external fixator components. Injury. 2005;36:1449-1452.
8. Svoboda SJ, Bice TG, Gooden HA, Brooks DE, Thomas DB, Wenke JC. Comparison of bulb syringe and pulsed lavage irrigation with use of a bioluminescent musculoskeletal wound model. J Bone Joint Surg Am. 2006;88:2167-2174.
9. Rocchetta HL, Boylan CJ, Foley JW, et al. Validation of a noninvasive, real-time imaging technology using bioluminescent Escherichia coli in the neutropenic mouse thigh model of infection. Antimicrob Agents Chemother. 2001;45:129-137.
10. Kadurugamuwa JL, Sin L, Albert E, et al. Direct continuous method for monitoring biofilm infection in a mouse model. Infect Immun. 2003;71: 882-890.
11. Charles CA, Ricotti CA, Davis SC, Mertz PM, Kirsner RS. Use of tissue-engineered skin to study in vitro biofilm development. Dermatol Surg. 2009;35:1334-1341.
12. Coester LM, Nepola JV, Allen J, Marsh L. The effects of silver coated external fixation pins. Iowa Orthop J. 2006;26:48-53.
13. Holt J, Hertzberg B, Weinhold P, Storm W, Schoenfisch M, Dahners L. Decreasing bacterial colonization of external fixation pins through nitric oxide release coatings. J Orthop Trauma. 2011;25:432-437.
14. Watson JT, Occhietti MJ, Moed BR, Karges DE, Cramer KE, Parmar VS. Perioperative External Fixator Management During Secondary Surgical Procedures. Presented at: Orthopaedic Trauma Association Annual Meeting; Charlotte, North Carolina; 1999.
15. Darouiche RO, Wall MJ Jr, Itani KM, Otterson MF, Webb AL, Carrick MM, et al. Chlorhexidine-alcohol versus povidone-iodine for surgical site antisepsis. N Engl J Med. 2010;362:18-26.
16. Bibbo C, Patel DV, Gehrmann RM, Linn SS. Chlorhexidine provides superior skin decontamination in foot and ankle surgery: a prospective randomized study. Clin Ortop Relat Res. 2005;438:204-208.
17. Noorani A, Rabey N, Walsh SR, Davies RJ. Systematic review and meta-analysis of preoperative antisepsis with chlorhexidine versus povidone-iodine in clean-contaminated surgery. Br J Surg. 2010;97: 1614-1620.