Modification of interface between regulatory and essential light chains hampers phosphorylation-dependent activation of smooth muscle myosin

Journal of Biological Chemistry

Volumn 287, Issue 26, 2012, Pages 22068-22079

  Ni, Shaowei ^a   Hong, Feng ^a   Haldeman, Brian D ^a   Baker, Josh E ^a   Facemyer, Kevin C ^a   Cremo, Christine R ^a  

^a UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC MECHANISMS; ATP BINDING; ATP-ASE ACTIVITY; ESSENTIAL LIGHT CHAINS; HEAVY CHAIN; HEAVY MEROMYOSIN; INCREASED FLEXIBILITY; MYOSIN II; REGULATORY DOMAIN; REGULATORY LIGHT CHAINS; SCALLOP MYOSIN; SMOOTH MUSCLES; STRUCTURAL FUNCTION; WILD TYPES;

MOLECULAR DYNAMICS; MUSCLE; PHOSPHORYLATION; PROTEINS; SHELLFISH;

INTERFACE STATES;

ACTIN; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; MEROMYOSIN; MYOSIN; MYOSIN II;

ALLOSTERISM; ANIMAL TISSUE; ARTICLE; BINDING SITE; CHICKEN; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME REGULATION; ESSENTIAL LIGHT CHAIN; MOLECULAR DYNAMICS; MOTOR PERFORMANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; PROTEIN STRUCTURE; REGULATORY LIGHT CHAIN; REGULATORY MECHANISM; SEQUENCE ALIGNMENT; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE RELAXATION; STRUCTURE ACTIVITY RELATION;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CELL LINE; CHICKENS; HUMANS; INSECTS; KINETICS; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; MUSCLE, SMOOTH; MUTATION; MYOSIN LIGHT CHAINS; MYOSIN SUBFRAGMENTS; PHOSPHORYLATION; SEQUENCE HOMOLOGY, AMINO ACID; SMOOTH MUSCLE MYOSINS;

EID: 84862637853     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.343491     Document Type: Article

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