Molecular targeting of CEACAM6 using antibody probes of different sizes

Journal of Controlled Release

Volumn 161, Issue 1, 2012, Pages 18-24

  Niu, Gang ^a   Murad, Yanal M ^b   Gao, Haokao ^a   Hu, Shuo ^a   Guo, Ning ^a   Jacobson, Orit ^a   Nguyen, Thanh Dung ^b   Zhang, Jianbing ^b   Chen, Xiaoyuan ^a  

^a NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING   (United States)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

64Cu; CEACAM6; Heavy chain antibody; Pancreatic cancer; Positron emission tomography (PET)

Indexed keywords

CEACAM6; CELL ADHESION MOLECULES; DIFFERENT SIZES; EX-VIVO; HEAVY-CHAIN ANTIBODIES; HUMAN MALIGNANCIES; IMMUNOSTAINING; MOLECULAR TARGETING; MONOCLONAL ANTIBODIES (MAB); PANCREATIC CANCERS; PANCREATIC TUMORS; POTENTIAL TARGETS; SINGLE DOMAINS; THERAPEUTIC INDEX; TUMOR DETECTION; TUMOR TARGETING; TUMOR UPTAKE; WHOLE-BODY;

DISEASES; MEDICAL IMAGING; MONOCLONAL ANTIBODIES; POSITRON EMISSION TOMOGRAPHY; TUMORS;

CHEMICAL DETECTION;

2A3 MFC ANTIBODY; 2A3 MONOCLONAL ANTIBODY; 9A6 MONOCLONAL ANTIBODY; ANTIBODY; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 6; COPPER 64; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG HALF LIFE; EX VIVO STUDY; FEMALE; FLOW CYTOMETRY; HEAVY CHAIN; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LIVER; MOLECULAR PROBE; MOLECULAR SIZE; MOLECULARLY TARGETED THERAPY; MOUSE; NONHUMAN; PANCREAS TUMOR; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN TARGETING; SURFACE PLASMON RESONANCE; TUMOR XENOGRAFT;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; CELL ADHESION MOLECULES; CELL LINE; CELL LINE, TUMOR; COPPER RADIOISOTOPES; FEMALE; GPI-LINKED PROTEINS; HUMANS; MICE; MICE, NUDE; MOLECULAR IMAGING; NEOPLASM TRANSPLANTATION; PANCREATIC NEOPLASMS; POSITRON-EMISSION TOMOGRAPHY; SPLEEN; TRANSPLANTATION, HETEROLOGOUS;

EID: 84862632888     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.04.043     Document Type: Article

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