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Volumn 463, Issue 3, 2012, Pages 429-447

Adipocyte differentiation-specific gene transcriptional response to C18 unsaturated fatty acids plus insulin

Author keywords

Adipocyte differentiation; Gene expression; Genistein; LCFAs; Linoleic acid; LY294002; Oil Red O staining; Oleic acid

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; DEXAMETHASONE; FATTY ACID BINDING PROTEIN 4; GENISTEIN; INSULIN; LINOLEIC ACID; LONG CHAIN FATTY ACID; OLEIC ACID; PALMITIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STEARIC ACID; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; 2 MORPHOLINO 8 PHENYLCHROMONE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; CHROMONE DERIVATIVE; MORPHOLINE DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE;

EID: 84862621832     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-011-1066-7     Document Type: Article
Times cited : (20)

References (62)
  • 2
    • 0025947445 scopus 로고
    • Regulation of adipose cell differentiation. II. Kinetics of induction of the aP2 gene by fatty acids and modulation by dexamethasone
    • Amri EZ, Ailhaud G, Grimaldi P (1991) Regulation of adipose cell differentiation. II. Kinetics of induction of the aP2 gene by fatty acids and modulation by dexamethasone. J Lipid Res 32(9):1457-1463
    • (1991) J Lipid Res , vol.32 , Issue.9 , pp. 1457-1463
    • Amri, E.Z.1    Ailhaud, G.2    Grimaldi, P.3
  • 3
    • 0025951065 scopus 로고
    • Regulation of adipose cell differentiation. I. Fatty acids are inducers of the aP2 gene expression
    • Amri EZ, Bertrand B, Ailhaud G, Grimaldi P (1991) Regulation of adipose cell differentiation. I. Fatty acids are inducers of the aP2 gene expression. J Lipid Res 32(9):1449-1456
    • (1991) J Lipid Res , vol.32 , Issue.9 , pp. 1449-1456
    • Amri, E.Z.1    Bertrand, B.2    Ailhaud, G.3    Grimaldi, P.4
  • 4
    • 0028909362 scopus 로고
    • Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes. Homology to peroxisome proliferatoractivated receptors
    • Amri EZ, Bonino F, Ailhaud G, Abumrad NA, Grimaldi PA (1995) Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes. Homology to peroxisome proliferatoractivated receptors. J Biol Chem 270(5):2367-2371
    • (1995) J Biol Chem , vol.270 , Issue.5 , pp. 2367-2371
    • Amri, E.Z.1    Bonino, F.2    Ailhaud, G.3    Abumrad, N.A.4    Grimaldi, P.A.5
  • 5
    • 0029866946 scopus 로고    scopus 로고
    • Fatty acids regulate the expression of lipoprotein lipase gene and activity in preadipose and adipose cells
    • Amri EZ, Teboul L, Vannier C, Grimaldi PA, Ailhaud G (1996) Fatty acids regulate the expression of lipoprotein lipase gene and activity in preadipose and adipose cells. Biochem J 314(Pt 2):541-546
    • (1996) Biochem J , vol.314 , Issue.PART 2 , pp. 541-546
    • Amri, E.Z.1    Teboul, L.2    Vannier, C.3    Grimaldi, P.A.4    Ailhaud, G.5
  • 6
    • 0036183630 scopus 로고    scopus 로고
    • The mechanisms of action of PPARs
    • Berger J, Moller DE (2002) The mechanisms of action of PPARs. Annu Rev Med 53:409-435
    • (2002) Annu Rev Med , vol.53 , pp. 409-435
    • Berger, J.1    Moller, D.E.2
  • 7
    • 85047691476 scopus 로고    scopus 로고
    • How does blood glucose control with insulin save lives in intensive care?
    • doi:10.1172/JCI200423506
    • Berghe GVd (2004) How does blood glucose control with insulin save lives in intensive care? J Clin Invest 114(9):1187-1195. doi:10.1172/JCI200423506
    • (2004) J Clin Invest , vol.114 , Issue.9 , pp. 1187-1195
    • Berghe, G.Vd.1
  • 8
    • 0030897118 scopus 로고    scopus 로고
    • Endogenous synthesis cannot compensate for absence of dietary oleic acid in rats
    • Bourre JM, Dumont OL, Clement ME, Durand GA (1997) Endogenous synthesis cannot compensate for absence of dietary oleic acid in rats. J Nutr 127(3):488-493
    • (1997) J Nutr , vol.127 , Issue.3 , pp. 488-493
    • Bourre, J.M.1    Dumont, O.L.2    Clement, M.E.3    Durand, G.A.4
  • 9
    • 0028308412 scopus 로고
    • Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp 70 S6 kinase, DNA synthesis, and glucose transporter translocation
    • Cheatham B, Vlahos CJ, Cheatham L, Wang L, Blenis J, Kahn CR (1994) Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp 70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol Cell Biol 14(7):4902-4911
    • (1994) Mol Cell Biol , vol.14 , Issue.7 , pp. 4902-4911
    • Cheatham, B.1    Vlahos, C.J.2    Cheatham, L.3    Wang, L.4    Blenis, J.5    Kahn, C.R.6
  • 10
    • 0033793133 scopus 로고    scopus 로고
    • Peroxisome proliferatoractivated receptors (PPARs): Nuclear receptors at the crossroads between lipid metabolism and inflammation
    • Chinetti G, Fruchart JC, Staels B (2000) Peroxisome proliferatoractivated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation. Inflamm Res 49 (10):497-505
    • (2000) Inflamm Res , vol.49 , Issue.10 , pp. 497-505
    • Chinetti, G.1    Fruchart, J.C.2    Staels, B.3
  • 11
    • 0035156845 scopus 로고    scopus 로고
    • Fatty acids modulate porcine adipocyte differentiation and transcripts for transcription factors and adipocyte-characteristic proteins*
    • Ding S, Mersmann HJ (2001) Fatty acids modulate porcine adipocyte differentiation and transcripts for transcription factors and adipocyte-characteristic proteins*. J Nutr Biochem 12(2):101-108
    • (2001) J Nutr Biochem , vol.12 , Issue.2 , pp. 101-108
    • Ding, S.1    Mersmann, H.J.2
  • 12
    • 0036626851 scopus 로고    scopus 로고
    • Modulation of adipocyte determination and differentiation-dependent factor 1 byselected polyunsaturated fatty acids
    • Ding ST, McNeel RL, Mersmann HJ (2002) Modulation of adipocyte determination and differentiation-dependent factor 1 byselected polyunsaturated fatty acids. Vitro Cell Dev Biol Anim 38(6):352-357
    • (2002) Vitro Cell Dev Biol Anim , vol.38 , Issue.6 , pp. 352-357
    • Ding, S.T.1    McNeel, R.L.2    Mersmann, H.J.3
  • 13
    • 0026739556 scopus 로고
    • Fatty acid regulation of gene expression. Transcriptional and post-transcriptional mechanisms
    • Distel RJ, Robinson GS, Spiegelman BM (1992) Fatty acid regulation of gene expression. Transcriptional and post-transcriptional mechanisms. J Biol Chem 267(9):5937-5941
    • (1992) J Biol Chem , vol.267 , Issue.9 , pp. 5937-5941
    • Distel, R.J.1    Robinson, G.S.2    Spiegelman, B.M.3
  • 14
    • 29244459130 scopus 로고    scopus 로고
    • Insulin and oleic acid increase PPARgamma2 expression in cultured mouse hepatocytes
    • doi:10.1016/j.bbrc.2005.12.008
    • Edvardsson U, Ljungberg A, Oscarsson J (2006) Insulin and oleic acid increase PPARgamma2 expression in cultured mouse hepatocytes. Biochem Biophys Res Commun 340(1):111-117. doi:10.1016/j.bbrc.2005.12.008
    • (2006) Biochem Biophys Res Commun , vol.340 , Issue.1 , pp. 111-117
    • Edvardsson, U.1    Ljungberg, A.2    Oscarsson, J.3
  • 15
    • 0018267913 scopus 로고
    • Role of tyrosyl and arginyl residues in rat liver microsomal stearylcoenzyme A desaturase
    • Enoch HG, Strittmatter P (1978) Role of tyrosyl and arginyl residues in rat liver microsomal stearylcoenzyme A desaturase. Biochemistry 17(23):4927-4932
    • (1978) Biochemistry , vol.17 , Issue.23 , pp. 4927-4932
    • Enoch, H.G.1    Strittmatter, P.2
  • 16
    • 0033607176 scopus 로고    scopus 로고
    • Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes
    • Foretz M, Guichard C, Ferre P, Foufelle F (1999) Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes. Proc Natl Acad Sci U S A 96(22):12737-12742
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.22 , pp. 12737-12742
    • Foretz, M.1    Guichard, C.2    Ferre, P.3    Foufelle, F.4
  • 18
    • 0030952937 scopus 로고    scopus 로고
    • Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta
    • Forman BM, Chen J, Evans RM (1997) Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci U S A 94(9):4312-4317
    • (1997) Proc Natl Acad Sci U S A , vol.94 , Issue.9 , pp. 4312-4317
    • Forman, B.M.1    Chen, J.2    Evans, R.M.3
  • 19
    • 0026551309 scopus 로고
    • Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor
    • Gottlicher M, Widmark E, Li Q, Gustafsson JA (1992) Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor. Proc Natl Acad Sci U S A 89(10):4653-4657
    • (1992) Proc Natl Acad Sci U S A , vol.89 , Issue.10 , pp. 4653-4657
    • Gottlicher, M.1    Widmark, E.2    Li, Q.3    Gustafsson, J.A.4
  • 20
    • 0032960137 scopus 로고    scopus 로고
    • Long chain fatty acids as modulators of gene transcription in preadipose cells
    • Grimaldi PA, Teboul L, Gaillard D, Armengod AV, Amri EZ (1999) Long chain fatty acids as modulators of gene transcription in preadipose cells. Mol Cell Biochem 192(1-2):63-68
    • (1999) Mol Cell Biochem , vol.192 , Issue.1-2 , pp. 63-68
    • Grimaldi, P.A.1    Teboul, L.2    Gaillard, D.3    Armengod, A.V.4    Amri, E.Z.5
  • 21
    • 0036401857 scopus 로고    scopus 로고
    • Fatty acid transport across membranes: Relevance to nutrition and metabolic pathology
    • doi:10.1146/annurev.nutr.22.020402.130846
    • Hajri T, Abumrad NA (2002) Fatty acid transport across membranes: relevance to nutrition and metabolic pathology. Annu Rev Nutr 22:383-415. doi:10.1146/annurev.nutr.22.020402.130846
    • (2002) Annu Rev Nutr , vol.22 , pp. 383-415
    • Hajri, T.1    Abumrad, N.A.2
  • 23
    • 0034996015 scopus 로고    scopus 로고
    • Differential effects of flavonoids on 3T3-L1 adipogenesis and lipolysis
    • Harmon AW, Harp JB (2001) Differential effects of flavonoids on 3T3-L1 adipogenesis and lipolysis. Am J Physiol Cell Physiol 280 (4):C807-C813
    • (2001) Am J Physiol Cell Physiol , vol.280 , Issue.4
    • Harmon, A.W.1    Harp, J.B.2
  • 24
    • 0036799766 scopus 로고    scopus 로고
    • Genistein inhibits CCAAT/enhancer-binding protein beta (C/EBPbeta) activity and 3T3-L1 adipogenesis by increasing C/EBP homologous protein expression
    • doi:10.1042/BJ20020300
    • Harmon AW, Patel YM, Harp JB (2002) Genistein inhibits CCAAT/enhancer-binding protein beta (C/EBPbeta) activity and 3T3-L1 adipogenesis by increasing C/EBP homologous protein expression. Biochem J 367(Pt 1):203-208. doi:10.1042/BJ20020300
    • (2002) Biochem J , vol.367 , Issue.PART 1 , pp. 203-208
    • Harmon, A.W.1    Patel, Y.M.2    Harp, J.B.3
  • 25
    • 0033609911 scopus 로고    scopus 로고
    • Identification of wortmanninsensitive targets in 3T3-L1 adipocytes. DissociationoOf insulinstimulated glucose uptake and glut4 translocation
    • Hausdorff SF, Fingar DC, Morioka K, Garza LA, Whiteman EL, Summers SA, Birnbaum MJ (1999) Identification of wortmanninsensitive targets in 3T3-L1 adipocytes. DissociationoOf insulinstimulated glucose uptake and glut4 translocation. J Biol Chem 274(35):24677-24684
    • (1999) J Biol Chem , vol.274 , Issue.35 , pp. 24677-24684
    • Hausdorff, S.F.1    Fingar, D.C.2    Morioka, K.3    Garza, L.A.4    Whiteman, E.L.5    Summers, S.A.6    Birnbaum, M.J.7
  • 26
    • 10744224568 scopus 로고    scopus 로고
    • The phytoestrogen genistein enhances osteogenesis and represses adipogenic differentiation of human primary bone marrow stromal cells
    • doi:10.1210/en.2003-1014
    • Heim M, Frank O, Kampmann G, Sochocky N, Pennimpede T, Fuchs P, Hunziker W, Weber P, Martin I, Bendik I (2004) The phytoestrogen genistein enhances osteogenesis and represses adipogenic differentiation of human primary bone marrow stromal cells. Endocrinology 145(2):848-859. doi:10.1210/en.2003-1014
    • (2004) Endocrinology , vol.145 , Issue.2 , pp. 848-859
    • Heim, M.1    Frank, O.2    Kampmann, G.3    Sochocky, N.4    Pennimpede, T.5    Fuchs, P.6    Hunziker, W.7    Weber, P.8    Martin, I.9    Bendik, I.10
  • 27
    • 0001141551 scopus 로고    scopus 로고
    • Fatty acid transporters in animal cells
    • Hui TY, Bernlohr DA (1997) Fatty acid transporters in animal cells. Front Biosci 2:d222-d231
    • (1997) Front Biosci , vol.2
    • Hui, T.Y.1    Bernlohr, D.A.2
  • 29
    • 27744455616 scopus 로고    scopus 로고
    • Genistein, EGCG, and capsaicin inhibit adipocyte differentiation process via activating AMP-activated protein kinase
    • doi:10.1016/j.bbrc.2005.09.195
    • Hwang JT, Park IJ, Shin JI, Lee YK, Lee SK, Baik HW, Ha J, Park OJ (2005) Genistein, EGCG, and capsaicin inhibit adipocyte differentiation process via activating AMP-activated protein kinase. Biochem Biophys Res Commun 338(2):694-699. doi:10.1016/j.bbrc.2005.09.195
    • (2005) Biochem Biophys Res Commun , vol.338 , Issue.2 , pp. 694-699
    • Hwang, J.T.1    Park, I.J.2    Shin, J.I.3    Lee, Y.K.4    Lee, S.K.5    Baik, H.W.6    Ha, J.7    Park, O.J.8
  • 30
    • 0027447461 scopus 로고
    • Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers
    • Keller H, Dreyer C, Medin J, Mahfoudi A, Ozato K, Wahli W (1993) Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers. Proc Natl Acad Sci U S A 90(6):2160-2164
    • (1993) Proc Natl Acad Sci U S A , vol.90 , Issue.6 , pp. 2160-2164
    • Keller, H.1    Dreyer, C.2    Medin, J.3    Mahfoudi, A.4    Ozato, K.5    Wahli, W.6
  • 31
    • 76749093608 scopus 로고    scopus 로고
    • Antiobesity mechanisms of action of conjugated linoleic acid
    • doi:10.1016/j.jnutbio.2009.08.003
    • Kennedy A, Martinez K, Schmidt S, Mandrup S, LaPoint K, McIntosh M (2010) Antiobesity mechanisms of action of conjugated linoleic acid. J Nutr Biochem 21(3):171-179. doi:10.1016/j.jnutbio.2009.08.003
    • (2010) J Nutr Biochem , vol.21 , Issue.3 , pp. 171-179
    • Kennedy, A.1    Martinez, K.2    Schmidt, S.3    Mandrup, S.4    LaPoint, K.5    McIntosh, M.6
  • 32
    • 0032516081 scopus 로고    scopus 로고
    • ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand
    • Kim JB, Wright HM, Wright M, Spiegelman BM (1998) ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand. Proc Natl Acad Sci U S A 95(8):4333-4337
    • (1998) Proc Natl Acad Sci U S A , vol.95 , Issue.8 , pp. 4333-4337
    • Kim, J.B.1    Wright, H.M.2    Wright, M.3    Spiegelman, B.M.4
  • 33
    • 78149482135 scopus 로고    scopus 로고
    • The inhibitory effect of genistein on hepatic steatosis is linked to visceral adipocyte metabolism in mice with diet-induced non-alcoholic fatty liver disease
    • doi:10.1017/S0007114510002266
    • Kim MH, Kang KS, Lee YS The inhibitory effect of genistein on hepatic steatosis is linked to visceral adipocyte metabolism in mice with diet-induced non-alcoholic fatty liver disease. Br J Nutr 104 (9):1333-1342. doi:10.1017/S0007114510002266
    • Br J Nutr , vol.104 , Issue.9 , pp. 1333-1342
    • Kim, M.H.1    Kang, K.S.2    Lee, Y.S.3
  • 34
    • 78049453745 scopus 로고    scopus 로고
    • Genistein and daidzein repress adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells via Wnt/beta-catenin signalling or lipolysis
    • doi:10.1111/j.1365-2184.2010.00709.x
    • Kim MH, Park JS, Seo MS, Jung JW, Lee YS, Kang KS Genistein and daidzein repress adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells via Wnt/beta-catenin signalling or lipolysis. Cell Prolif 43(6):594-605. doi:10.1111/j.1365-2184.2010.00709.x
    • Cell Prolif , vol.43 , Issue.6 , pp. 594-605
    • Kim, M.H.1    Park, J.S.2    Seo, M.S.3    Jung, J.W.4    Lee, Y.S.5    Kang, K.S.6
  • 35
    • 42649139910 scopus 로고    scopus 로고
    • Regulation of lipid accumulation in 3T3-L1 cells: Insulinindependent and combined effects of fatty acids and insulin
    • Kokta TASAL, Papasani MR, Szasz JI, Dodson MV, Hill RA (2008) Regulation of lipid accumulation in 3T3-L1 cells: insulinindependent and combined effects of fatty acids and insulin. Animal 2(1):92-99
    • (2008) Animal , vol.2 , Issue.1 , pp. 92-99
    • Kokta, T.A.S.A.L.1    Papasani, M.R.2    Szasz, J.I.3    Dodson, M.V.4    Hill, R.A.5
  • 36
    • 14244263906 scopus 로고    scopus 로고
    • Genistein activates the 3′,5&prime- cyclic adenosine monophosphate signaling pathway in vascular endothelial cells and protects endothelial barrier function
    • doi:10.1210/en.2004-1221
    • Liu D, Jiang H, Grange RW (2005) Genistein activates the 3′,5&prime- cyclic adenosine monophosphate signaling pathway in vascular endothelial cells and protects endothelial barrier function. Endocrinology 146(3):1312-1320. doi:10.1210/en.2004-1221
    • (2005) Endocrinology , vol.146 , Issue.3 , pp. 1312-1320
    • Liu, D.1    Jiang, H.2    Grange, R.W.3
  • 37
    • 0029062839 scopus 로고
    • Transcriptional regulation of gene-expression during adipocyte differentiation
    • Macdougald OA, Lane MD (1995) Transcriptional regulation of gene-expression during adipocyte differentiation. Annu Rev Biochem 64:345-373
    • (1995) Annu Rev Biochem , vol.64 , pp. 345-373
    • Macdougald, O.A.1    Lane, M.D.2
  • 38
    • 20444381246 scopus 로고    scopus 로고
    • Regulation of adipocyte differentiation and function by polyunsaturated fatty acids
    • Madsen L, Petersen RK, Kristiansen K (2005) Regulation of adipocyte differentiation and function by polyunsaturated fatty acids. Biochim Biophys Acta 1740(2):266-286
    • (2005) Biochim Biophys Acta , vol.1740 , Issue.2 , pp. 266-286
    • Madsen, L.1    Petersen, R.K.2    Kristiansen, K.3
  • 39
    • 0032871502 scopus 로고    scopus 로고
    • Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol
    • Ntambi JM (1999) Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol. J Lipid Res 40(9):1549-1558
    • (1999) J Lipid Res , vol.40 , Issue.9 , pp. 1549-1558
    • Ntambi, J.M.1
  • 40
    • 0024297268 scopus 로고
    • Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase
    • Ntambi JM, Buhrow SA, Kaestner KH, Christy RJ, Sibley E, Kelly TJ Jr, Lane MD (1988) Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase. J Biol Chem 263(33):17291-17300
    • (1988) J Biol Chem , vol.263 , Issue.33 , pp. 17291-17300
    • Ntambi, J.M.1    Buhrow, S.A.2    Kaestner, K.H.3    Christy, R.J.4    Sibley, E.5    Kelly Jr., T.J.6    Lane, M.D.7
  • 41
    • 0029992478 scopus 로고    scopus 로고
    • A model cell line to study regulation of stearoyl-CoA desaturase gene 1 expression by insulin and polyunsaturated fatty acids
    • doi:10.1006/bbrc.1996.0520
    • Ntambi JM, Sessler AM, Takova T (1996) A model cell line to study regulation of stearoyl-CoA desaturase gene 1 expression by insulin and polyunsaturated fatty acids. Biochem Biophys Res Commun 220(3):990-995. doi:10.1006/bbrc.1996.0520
    • (1996) Biochem Biophys Res Commun , vol.220 , Issue.3 , pp. 990-995
    • Ntambi, J.M.1    Sessler, A.M.2    Takova, T.3
  • 42
    • 0030785197 scopus 로고    scopus 로고
    • Fatty acids involved in signal cross-talk between cell membrane and nucleus
    • Nunez EA (1997) Fatty acids involved in signal cross-talk between cell membrane and nucleus. Prostaglandins Leukot Essent Fatty Acids 57(4-5):429-434
    • (1997) Prostaglandins Leukot Essent Fatty Acids , vol.57 , Issue.4-5 , pp. 429-434
    • Nunez, E.A.1
  • 43
    • 0035932990 scopus 로고    scopus 로고
    • Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR
    • doi:10.1073/pnas.11113869898/11/6027
    • Ou J, Tu H, Shan B, Luk A, DeBose-Boyd RA, Bashmakov Y, Goldstein JL, Brown MS (2001) Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR. Proc Natl Acad Sci U S A 98(11):6027-6032. doi:10.1073/pnas.11113869898/11/6027
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.11 , pp. 6027-6032
    • Ou, J.1    Tu, H.2    Shan, B.3    Luk, A.4    DeBose-Boyd, R.A.5    Bashmakov, Y.6    Goldstein, J.L.7    Brown, M.S.8
  • 44
    • 58149139398 scopus 로고    scopus 로고
    • Genistein inhibits differentiation of primary human adipocytes
    • doi:10.1016/j.jnutbio.2008.01.006
    • Park HJ, Della-Fera MA, Hausman DB, Rayalam S, Ambati S, Baile CA (2009) Genistein inhibits differentiation of primary human adipocytes. J Nutr Biochem 20(2):140-148. doi:10.1016/j.jnutbio.2008.01.006
    • (2009) J Nutr Biochem , vol.20 , Issue.2 , pp. 140-148
    • Park, H.J.1    Della-Fera, M.A.2    Hausman, D.B.3    Rayalam, S.4    Ambati, S.5    Baile, C.A.6
  • 45
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29 (9):-
    • (2001) Nucleic Acids Res , vol.29 , Issue.9
    • Pfaffl, M.W.1
  • 47
    • 0026793195 scopus 로고
    • Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with oil Red-O
    • Ramirezzacarias JL, Castromunozledo F, Kuriharcuch W (1992) Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with oil Red-O. Histochemistry 97(6):493-497
    • (1992) Histochemistry , vol.97 , Issue.6 , pp. 493-497
    • Ramirezzacarias, J.L.1    Castromunozledo, F.2    Kuriharcuch, W.3
  • 49
    • 0035856949 scopus 로고    scopus 로고
    • Insulin signalling and the regulation of glucose and lipid metabolism
    • doi:10.1038/414799a414799a
    • Saltiel AR, Kahn CR (2001) Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414(6865):799-806. doi:10.1038/ 414799a414799a
    • (2001) Nature , vol.414 , Issue.6865 , pp. 799-806
    • Saltiel, A.R.1    Kahn, C.R.2
  • 50
    • 0029860445 scopus 로고    scopus 로고
    • Regulation of stearoyl-CoA desaturase 1 mRNA stability by polyunsaturated fatty acids in 3T3-L1 adipocytes
    • Sessler AM, Kaur N, Palta JP, Ntambi JM (1996) Regulation of stearoyl-CoA desaturase 1 mRNA stability by polyunsaturated fatty acids in 3T3-L1 adipocytes. J Biol Chem 271(47):29854-29858
    • (1996) J Biol Chem , vol.271 , Issue.47 , pp. 29854-29858
    • Sessler, A.M.1    Kaur, N.2    Palta, J.P.3    Ntambi, J.M.4
  • 52
    • 34247891519 scopus 로고    scopus 로고
    • Genistein downregulates SREBP-1 regulated gene expression by inhibiting site-1 protease expression in HepG2 cells
    • Shin ES, Lee HH, Cho SY, Park HW, Lee SJ, Lee TR (2007) Genistein downregulates SREBP-1 regulated gene expression by inhibiting site-1 protease expression in HepG2 cells. J Nutr 137 (5):1127-1131
    • (2007) J Nutr , vol.137 , Issue.5 , pp. 1127-1131
    • Shin, E.S.1    Lee, H.H.2    Cho, S.Y.3    Park, H.W.4    Lee, S.J.5    Lee, T.R.6
  • 53
    • 0036228690 scopus 로고    scopus 로고
    • Insulin causes fatty acid transport protein translocation and enhanced fatty acid uptake in adipocytes
    • Stahl A, Evans JG, Pattel S, Hirsch D, Lodish HF (2002) Insulin causes fatty acid transport protein translocation and enhanced fatty acid uptake in adipocytes. Dev Cell 2(4):477-488
    • (2002) Dev Cell , vol.2 , Issue.4 , pp. 477-488
    • Stahl, A.1    Evans, J.G.2    Pattel, S.3    Hirsch, D.4    Lodish, H.F.5
  • 54
    • 70350464323 scopus 로고    scopus 로고
    • Minireview: Pref-1: Role in adipogenesis and mesenchymal cell fate
    • Sul HS (2009) Minireview: Pref-1: role in adipogenesis and mesenchymal cell fate. Mol Endocrinol 23(11):1717-1725
    • (2009) Mol Endocrinol , vol.23 , Issue.11 , pp. 1717-1725
    • Sul, H.S.1
  • 55
    • 0032823204 scopus 로고    scopus 로고
    • Both wortmannin and simvastatin inhibit the adipogenesis in 3T3-L1 cells during the late phase of differentiation
    • Tomiyama K, Nishio E, Watanabe Y (1999) Both wortmannin and simvastatin inhibit the adipogenesis in 3T3-L1 cells during the late phase of differentiation. Jpn J Pharmacol 80(4):375-378
    • (1999) Jpn J Pharmacol , vol.80 , Issue.4 , pp. 375-378
    • Tomiyama, K.1    Nishio, E.2    Watanabe, Y.3
  • 56
    • 0028180070 scopus 로고
    • mPPAR gamma 2: Tissue-specific regulator of an adipocyte enhancer
    • Tontonoz P, Hu E, Graves RA, Budavari AI, Spiegelman BM (1994) mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer. Genes Dev 8(10):1224-1234
    • (1994) Genes Dev , vol.8 , Issue.10 , pp. 1224-1234
    • Tontonoz, P.1    Hu, E.2    Graves, R.A.3    Budavari, A.I.4    Spiegelman, B.M.5
  • 57
    • 0029043699 scopus 로고
    • Wortmannin inhibits insulin-induced Ras and mitogen-activated protein kinase activation related to adipocyte differentiation in 3T3-L1 fibroblasts
    • doi:10.1006/bbrc.1995.1698
    • Uehara T, Tokumitsu Y, Nomura Y (1995) Wortmannin inhibits insulin-induced Ras and mitogen-activated protein kinase activation related to adipocyte differentiation in 3T3-L1 fibroblasts. Biochem Biophys Res Commun 210(2):574-580. doi:10.1006/bbrc.1995.1698
    • (1995) Biochem Biophys Res Commun , vol.210 , Issue.2 , pp. 574-580
    • Uehara, T.1    Tokumitsu, Y.2    Nomura, Y.3
  • 58
    • 0028170210 scopus 로고
    • A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
    • Vlahos CJ, Matter WF, Hui KY, Brown RF (1994) A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem 269(7):5241-5248
    • (1994) J Biol Chem , vol.269 , Issue.7 , pp. 5241-5248
    • Vlahos, C.J.1    Matter, W.F.2    Hui, K.Y.3    Brown, R.F.4
  • 59
    • 0031560238 scopus 로고    scopus 로고
    • Localization of a polyunsaturated fatty acid response region in stearoyl-CoA desaturase gene 1
    • Waters KM, Miller CW, Ntambi JM (1997) Localization of a polyunsaturated fatty acid response region in stearoyl-CoA desaturase gene 1. Biochim Biophys Acta 1349(1):33-42
    • (1997) Biochim Biophys Acta , vol.1349 , Issue.1 , pp. 33-42
    • Waters, K.M.1    Miller, C.W.2    Ntambi, J.M.3
  • 60
    • 0029905399 scopus 로고    scopus 로고
    • Induction of peroxisome proliferator-activated receptor gamma during the conversion of 3T3 fibroblasts into adipocytes is mediated by C/EBPbeta, C/EBPdelta, and glucocorticoids
    • Wu Z, Bucher NL, Farmer SR (1996) Induction of peroxisome proliferator-activated receptor gamma during the conversion of 3T3 fibroblasts into adipocytes is mediated by C/EBPbeta, C/EBPdelta, and glucocorticoids. Mol Cell Biol 16(8):4128-4136
    • (1996) Mol Cell Biol , vol.16 , Issue.8 , pp. 4128-4136
    • Wu, Z.1    Bucher, N.L.2    Farmer, S.R.3
  • 62
    • 65649118867 scopus 로고    scopus 로고
    • Genistein suppresses adipogenesis of 3T3-L1 cells via multiple signal pathways
    • doi:10.1002/ptr.2724
    • Zhang M, Ikeda K, Xu JW, Yamori Y, Gao XM, Zhang BL (2009) Genistein suppresses adipogenesis of 3T3-L1 cells via multiple signal pathways. Phytother Res 23(5):713-718. doi:10.1002/ptr.2724
    • (2009) Phytother Res , vol.23 , Issue.5 , pp. 713-718
    • Zhang, M.1    Ikeda, K.2    Xu, J.W.3    Yamori, Y.4    Gao, X.M.5    Zhang, B.L.6


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